| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1975) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent Prodrug |
| UNII: | 826Y60901U |
| Parent Compound: | BETAMETHASONE |
Structure
| InChI Key | CIWBQSYVNNPZIQ-XYWKZLDCSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C28H37FO7 |
| Molecular Weight | 504.6 |
| AlogP | 3.82 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 106.97 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 36.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transcription factor
Nuclear receptor
Nuclear hormone receptor subfamily 3
Nuclear hormone receptor subfamily 3 group C
Nuclear hormone receptor subfamily 3 group C member 1
|
- | 5 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Periarthritis | 3 | D010489 | ClinicalTrials |
| Lichen Planus, Oral | 2 | D017676 | ClinicalTrials |
| Dermatitis, Atopic | 1 | D003876 | ClinicalTrials |
Related Entries
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 31276 |
| ChEMBL | CHEMBL1200384 |
| DrugCentral | 353 |
| EPA CompTox | DTXSID2022672 |
| FDA SRS | 826Y60901U |
| KEGG | D01637 |
| PubChem | 21800 |
| SureChEMBL | SCHEMBL7519 |
| ZINC | ZINC000004212137 |
CONTENTS