LORCASERIN HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (2012)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 0QJF08GDPE
Parent Compound: LORCASERIN

Structure
InChI Key ITIHHRMYZPNGRC-QRPNPIFTSA-N
Smile C[C@H]1CNCCc2ccc(Cl)cc21.Cl
InChI
InChI=1S/C11H14ClN.ClH/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9;/h2-3,6,8,13H,4-5,7H2,1H3;1H/t8-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C11H15Cl2N
Molecular Weight 232.15
AlogP 2.59
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 0.0
Polar Surface Area 12.03
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 13.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Serotonin 2c (5-HT2c) receptor agonist Expert

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Obesity 2 D009765 ClinicalTrials
Smoking Cessation 2 D016540 ClinicalTrials

Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Nervous system disorders
19.48
General disorders and administration site conditions
19.21
Psychiatric disorders
10.02
Cardiac disorders
9.25
Gastrointestinal disorders
7.81
Vascular disorders
7.72
Musculoskeletal and connective tissue disorders
4.85
Investigations
3.61
Respiratory, thoracic and mediastinal disorders
3.56
Metabolism and nutrition disorders
2.85
Skin and subcutaneous tissue disorders
2.17

Cross References

Resources Reference
ChEBI 65350
ChEMBL CHEMBL2095211
EPA CompTox DTXSID60233650
FDA SRS 0QJF08GDPE
PubChem 11658860
SureChEMBL SCHEMBL16672993
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