Trade Names: | |
Synonyms: | |
Status: | Approved (1959) |
Entry Type: | Small molecule |
Molecule Category: | Salt Prodrug |
UNII: | LEC9GKY20K |
Parent Compound: | METHYLPREDNISOLONE |
InChI Key | FQISKWAFAHGMGT-SGJOWKDISA-M |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C26H33NaO8 |
Molecular Weight | 496.53 |
AlogP | 2.22 |
Hydrogen Bond Acceptor | 7.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 6.0 |
Polar Surface Area | 138.2 |
Molecular species | ACID |
Aromatic Rings | 0.0 |
Heavy Atoms | 34.0 |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Glucocorticoid receptor agonist | FDA |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Inflammation | 4 | D007249 | ClinicalTrials |
Asthma | 4 | D001249 | ClinicalTrials |
Multiple Sclerosis, Chronic Progressive | 3 | D020528 | ClinicalTrials |
Deafness | 3 | D003638 | ClinicalTrials |
Graft vs Host Disease | 3 | D006086 | ClinicalTrials |
Glomerulonephritis, IGA | 3 | D005922 | ClinicalTrials |
Leukemia, Myeloid, Acute | 3 | D015470 | ClinicalTrials |
Vestibular Neuronitis | 3 | D020338 | ClinicalTrials |
Pneumonia | 3 | D011014 | ClinicalTrials |
Multiple Sclerosis, Chronic Progressive | 3 | D020528 | ClinicalTrials |
Severe Acute Respiratory Syndrome | 3 | D045169 | ClinicalTrials |
Pain | 3 | D010146 | ClinicalTrials |
Glomerulonephritis | 3 | D005921 | ClinicalTrials |
Graft vs Host Disease | 3 | D006086 | ClinicalTrials |
Severe Acute Respiratory Syndrome | 3 | D045169 | ClinicalTrials |
Leukemia, Lymphocytic, Chronic, B-Cell | 2 | D015451 | ClinicalTrials |
Leukemia, Mast-Cell | 2 | D007946 | ClinicalTrials |
Lymphoma, Non-Hodgkin | 2 | D008228 | ClinicalTrials |
Multiple Myeloma | 2 | D009101 | ClinicalTrials |
Chemical and Drug Induced Liver Injury | 2 | D056486 | ClinicalTrials |
Pneumonia, Bacterial | 2 | D018410 | ClinicalTrials |
Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2 | D054198 | ClinicalTrials |
Immune System Diseases | 1 | D007154 | ClinicalTrials |
Epilepsy | 1 | D004827 | ClinicalTrials |
Myelodysplastic Syndromes | 1 | D009190 | ClinicalTrials |
Lupus Erythematosus, Systemic | 0 | D008180 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 6890 |
ChEMBL | CHEMBL1201081 |
EPA CompTox | DTXSID2023303 |
FDA SRS | LEC9GKY20K |
PubChem | 23680530 |
SureChEMBL | SCHEMBL40947 |