Trade Names: | |
Synonyms: | |
Status: | Approved (1971) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | MZ1131787D |
Parent Compound: | NAPHAZOLINE |
InChI Key | DJDFFEBSKJCGHC-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C14H15ClN2 |
Molecular Weight | 246.74 |
AlogP | 2.38 |
Hydrogen Bond Acceptor | 2.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 2.0 |
Polar Surface Area | 24.39 |
Molecular species | BASE |
Aromatic Rings | 2.0 |
Heavy Atoms | 16.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Adrenergic receptor
|
12 | 0 | - | - | - | |
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 101 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Common Cold | 4 | D003139 | ClinicalTrials |
Influenza, Human | 3 | D007251 | ClinicalTrials |
Inflammation | 3 | D007249 | ClinicalTrials |
Pterygium | 3 | D011625 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 7470 |
ChEMBL | CHEMBL1706 |
EPA CompTox | DTXSID7045788 |
FDA SRS | MZ1131787D |
Guide to Pharmacology | 7310 |
KEGG | C07898 |
PubChem | 11079 |
SureChEMBL | SCHEMBL24153 |
ZINC | ZINC00125006 |