| Synonyms: | |
| Status: | Approved (1991) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | J05AD01 |
| UNII: | 364P9RVW4X |
Structure
| InChI Key | ZJAOAACCNHFJAH-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | CH3O5P |
| Molecular Weight | 126.0 |
| AlogP | -0.16 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 94.83 |
| Molecular species | ACID |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 7.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Hydrolase
|
- | 800-56000 | 400-13900 | - | - | |
|
Enzyme
Transferase
|
- | 2500-2500 | - | - | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC34 family of sodium phosphate co-transporters
|
- | - | - | - | 84 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Infections | 3 | D007239 | ClinicalTrials |
| Cytomegalovirus Retinitis | 3 | D017726 | ClinicalTrials |
| Cytomegalovirus Infections | 3 | D003586 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 4428-95-9 |
| ChEBI | 127780 |
| ChEMBL | CHEMBL666 |
| DrugBank | DB00529 |
| DrugCentral | 1241 |
| EPA CompTox | DTXSID0048478 |
| FDA SRS | 364P9RVW4X |
| Human Metabolome Database | HMDB0014670 |
| Guide to Pharmacology | 5497 |
| KEGG | C06456 |
| PDB | PPF |
| PharmGKB | PA449706 |
| PubChem | 3415 |
| SureChEMBL | SCHEMBL23633 |
| ZINC | ZINC000008101109 |
CONTENTS