| Synonyms: | |
| Status: | Approved (1957) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| UNII: | 3L5TQ84570 |
Structure
| InChI Key | OCJYIGYOJCODJL-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C25H27ClN2 |
| Molecular Weight | 390.96 |
| AlogP | 5.56 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 6.48 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 28.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC22 family of organic cation and anion transporters
|
- | - | - | - | 16 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Vertigo | 3 | D014717 | ClinicalTrials |
| Smoking Cessation | 2 | D016540 | ClinicalTrials |
| Carcinoma, Hepatocellular | 1 | D006528 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 569-65-3 |
| ChEBI | 6709 |
| ChEMBL | CHEMBL1623 |
| DrugBank | DB00737 |
| DrugCentral | 1649 |
| EPA CompTox | DTXSID0023242 |
| FDA SRS | 3L5TQ84570 |
| Human Metabolome Database | HMDB0014875 |
| Guide to Pharmacology | 2757 |
| KEGG | C07116 |
| PharmGKB | PA450338 |
| PubChem | 4034 |
| SureChEMBL | SCHEMBL4649 |
CONTENTS