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Therapeutic Area
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CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
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Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
RG6029
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Sodium channel protein type IX alpha subunit blocker
RG6029
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
KB-004
1
Antibody
Investigational
Unknown
Unknown
Glioblastoma; Myelodysplastic Syndromes; Primary Myelofibrosis
Ephrin type-A receptor 3 inhibitor
KB-004
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GDC-0152
1
Protein
Investigational
Unknown
Unknown
Neoplasms
Unknown
GDC-0152
×
Maximum Phase:
1
First Approval:
None
UNII:
4KW1M48SHS
Molecule Type:
Protein
Molecular Formula:
C25H34N6O3S
Molecular Weight:
498.65
AlogP:
2.81
PSA:
116.32
HBD:
3.0
HBA:
#RotB:
8.0
Source:
TB
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
TB
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
D6-25-HYDROXYVITAMIN D3
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
D6-25-HYDROXYVITAMIN D3
×
Maximum Phase:
1
First Approval:
None
UNII:
378HY809HV
Molecule Type:
Small molecule
Molecular Formula:
C27H44O2
Molecular Weight:
406.68
AlogP:
6.73
PSA:
40.46
HBD:
2.0
HBA:
#RotB:
6.0
Source:
TRANSTORINE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
TRANSTORINE
×
Maximum Phase:
1
First Approval:
None
UNII:
H030S2S85J
Molecule Type:
Small molecule
Molecular Formula:
C10H7NO3
Molecular Weight:
189.17
AlogP:
1.23
PSA:
70.16
HBD:
2.0
HBA:
#RotB:
1.0
Source:
ABC-008
1
Unknown
Investigational
Unknown
Unknown
Myositis, Inclusion Body
Unknown
ABC-008
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-791826
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BMS-791826
×
Maximum Phase:
1
First Approval:
None
UNII:
60BN6CDL0K
Molecule Type:
Small molecule
Molecular Formula:
C28H26FN5O3S
Molecular Weight:
531.61
AlogP:
5.73
PSA:
97.31
HBD:
1.0
HBA:
#RotB:
6.0
Source:
TRODUSQUEMINE
1
Small molecule
Investigational
Unknown
Unknown
Obesity
Unknown
TRODUSQUEMINE
×
Maximum Phase:
1
First Approval:
None
UNII:
KKC12PIF16
Molecule Type:
Small molecule
Molecular Formula:
C37H72N4O5S
Molecular Weight:
685.07
AlogP:
5.53
PSA:
145.94
HBD:
6.0
HBA:
#RotB:
20.0
Source:
RXDX-105
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
RXDX-105
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK2981278
1
Small molecule
Investigational
Unknown
Unknown
Psoriasis
Unknown
GSK2981278
×
Maximum Phase:
1
First Approval:
None
UNII:
L49V5G013I
Molecule Type:
Small molecule
Molecular Formula:
C25H35NO5S
Molecular Weight:
461.62
AlogP:
4.4
PSA:
76.07
HBD:
1.0
HBA:
#RotB:
10.0
Source:
BEXMARILIMAB
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Unknown
BEXMARILIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PF-04418948
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PF-04418948
×
Maximum Phase:
1
First Approval:
None
UNII:
I7Z38E70VF
Molecule Type:
Small molecule
Molecular Formula:
C23H20FNO5
Molecular Weight:
409.41
AlogP:
3.59
PSA:
76.07
HBD:
1.0
HBA:
#RotB:
6.0
Source:
VLX-1005
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
VLX-1005
×
Maximum Phase:
1
First Approval:
None
UNII:
JKU4XCC48Y
Molecule Type:
Small molecule
Molecular Formula:
C21H19N3O4S2
Molecular Weight:
441.53
AlogP:
4.42
PSA:
100.55
HBD:
3.0
HBA:
#RotB:
7.0
Source:
RG-7841
1
Unknown
Investigational
Unknown
Unknown
Neoplasms
Lymphocyte antigen 6E binding agent
RG-7841
×
Maximum Phase:
1
First Approval:
None
UNII:
ONS92I2A7F
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD5312
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
AZD5312
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PFK-158
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
PFK-158
×
Maximum Phase:
1
First Approval:
None
UNII:
2HOK1JQ203
Molecule Type:
Small molecule
Molecular Formula:
C18H11F3N2O
Molecular Weight:
328.29
AlogP:
4.54
PSA:
42.85
HBD:
0.0
HBA:
#RotB:
3.0
Source:
G1T28-1
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Cyclin-dependent kinase 4 inhibitor
G1T28-1
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SAFINGOL
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
SAFINGOL
×
Maximum Phase:
1
First Approval:
None
UNII:
OWA98U788S
Molecule Type:
Small molecule
Molecular Formula:
C18H39NO2
Molecular Weight:
301.52
AlogP:
4.15
PSA:
66.48
HBD:
3.0
HBA:
#RotB:
16.0
Source:
.ALPHA.-PYRROLIDINONONANOPHENONE
1
Small molecule
Investigational
Unknown
Unknown
Melanoma
Unknown
.ALPHA.-PYRROLIDINONONANOPHENONE
×
Maximum Phase:
1
First Approval:
None
UNII:
S3FKL8RY1D
Molecule Type:
Small molecule
Molecular Formula:
C19H29NO
Molecular Weight:
287.45
AlogP:
4.69
PSA:
20.31
HBD:
0.0
HBA:
#RotB:
9.0
Source:
NG-NITRO-L-ARGININE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
NG-NITRO-L-ARGININE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PROFILNINE SD
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
PROFILNINE SD
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LETRAZURIL
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LETRAZURIL
×
Maximum Phase:
1
First Approval:
None
UNII:
U8736VCB22
Molecule Type:
Small molecule
Molecular Formula:
C17H9Cl2FN4O2
Molecular Weight:
391.19
AlogP:
3.02
PSA:
91.54
HBD:
1.0
HBA:
#RotB:
3.0
Source:
ANSOFAXINE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ANSOFAXINE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK-945237
1
Small molecule
Investigational
Unknown
Unknown
Infections
Unknown
GSK-945237
×
Maximum Phase:
1
First Approval:
None
UNII:
U9T63BZ3AS
Molecule Type:
Small molecule
Molecular Formula:
C24H26FN5O3
Molecular Weight:
451.5
AlogP:
2.05
PSA:
81.51
HBD:
1.0
HBA:
#RotB:
5.0
Source:
RG7893
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Sodium channel protein type IX alpha subunit blocker
RG7893
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IMC-EB10
1
Antibody
Investigational
Unknown
Unknown
Leukemia, Myeloid
Tyrosine-protein kinase receptor FLT3 inhibitor
IMC-EB10
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ETIGILIMAB
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
T-cell immunoreceptor with Ig and ITIM domains inhibitor
ETIGILIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
FC1ZF28VIT
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IMGN-632
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute
Unknown
IMGN-632
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ON123300
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
ON123300
×
Maximum Phase:
1
First Approval:
None
UNII:
QJ8RO3296G
Molecule Type:
Small molecule
Molecular Formula:
C24H27N7O
Molecular Weight:
429.53
AlogP:
3.27
PSA:
90.08
HBD:
1.0
HBA:
#RotB:
4.0
Source:
VESENCUMAB
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Neuropilin-1 inhibitor
VESENCUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
7SF22186WT
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PAPAIN
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
PAPAIN
×
Maximum Phase:
1
First Approval:
None
UNII:
A236A06Y32
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ACHN-975
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ACHN-975
×
Maximum Phase:
1
First Approval:
None
UNII:
48CET2EN53
Molecule Type:
Small molecule
Molecular Formula:
C20H23N3O4
Molecular Weight:
369.42
AlogP:
0.01
PSA:
124.68
HBD:
5.0
HBA:
#RotB:
5.0
Source:
BORNEOL
1
Small molecule
Investigational
Unknown
Unknown
Angina, Stable
Unknown
BORNEOL
×
Maximum Phase:
1
First Approval:
None
UNII:
M89NIB437X
Molecule Type:
Small molecule
Molecular Formula:
C10H18O
Molecular Weight:
154.25
AlogP:
2.19
PSA:
20.23
HBD:
1.0
HBA:
#RotB:
0.0
Source:
CARBOMER 980
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
CARBOMER 980
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
1
2
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106
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Compound Name
Maximum Phase
Compound Structure
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Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA