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Total: 6532
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
TRANSDERMAL
Alzheimer Disease; Fibromyalgia; Stroke; Parkinson Disease; Restless Legs Syndrome
D2-like dopamine receptor agonist
Small molecule
Approved
Unknown
Unknown
Osteoporosis; Idiopathic Pulmonary Fibrosis; Essential Hypertension; Stroke; Hypertension; Marfan Syndrome; Severe Acute Respiratory Syndrome; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Colonic Neoplasms; Breast Neoplasms; Chordoma; Huntington Disease; Alzheimer Disease; Cerebellar Ataxia; Giant Cell Tumors; Glioma; Graft vs Host Disease; Hypertension, Pulmonary; Leukemia, Myeloid, Acute; Melanoma; Neurilemmoma; Parkinson Disease; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Synovitis, Pigmented Villonodular; Gastrointestinal Stromal Tumors; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Sarcoma; Neoplasms
Unknown
Small molecule
Approved
UROLOGY AND KIDNEY
INTRAVENOUS
Adenocarcinoma; Astrocytoma; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma; Colonic Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Genital Neoplasms, Female; Glioma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Neoplasms; Oligodendroglioma; Peritoneal Neoplasms; Prostatic Neoplasms; Urethral Neoplasms; Uterine Cervical Neoplasms; Adenoma; Arthritis, Rheumatoid; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Glioblastoma; Gliosarcoma; Hodgkin Disease; Insulinoma; Ischemia; Kidney Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Peripheral Arterial Disease; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Small Cell Lung Carcinoma; Somatostatinoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Hepatoblastoma; Lymphoma; Lymphoma, Mantle-Cell; Neoplasm Metastasis; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Carcinoma, Renal Cell; Neoplasms
FK506-binding protein 1A inhibitor
Small molecule
Approved
OTHER
INTRAVENOUS
Astrocytoma; Gliosarcoma; Head and Neck Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Verrucous; Colorectal Neoplasms; Fallopian Tube Neoplasms; Hypopharyngeal Neoplasms; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Melanoma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Tongue Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Endometrial Neoplasms; Breast Neoplasms; Neoplasms
Tubulin inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Parkinson Disease; Scleroderma, Systemic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Bcr/Abl fusion protein
Small molecule
Approved
Unknown
Unknown
Colorectal Neoplasms; Asthma; Dermatitis; Dermatitis, Atopic; Eczema; Rhinitis; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria; Hypersensitivity
Unknown
Small molecule
Approved
Unknown
Unknown
Heart Failure; Hypertension; Alzheimer Disease; Autistic Disorder; Hypertension, Portal; Lesch-Nyhan Syndrome; Liver Cirrhosis; Phenylketonurias; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic
Unknown
Small molecule
Approved
Unknown
ORAL
Urinary Bladder Neoplasms; Carcinoma, Renal Cell; Endometrial Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Thyroid Neoplasms; Adenocarcinoma; Brain Neoplasms; Carcinoma, Ductal; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Esophageal Neoplasms; Glioma; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pituitary Neoplasms; Stomach Neoplasms; Uterine Cervical Neoplasms; Brain Diseases; Breast Neoplasms; Head and Neck Neoplasms; Sarcoma; Neoplasms
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Hypertriglyceridemia; AIDS Dementia Complex; Arthritis, Rheumatoid; Cognitive Dysfunction; Graft vs Host Disease; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Stroke; Acquired Immunodeficiency Syndrome; Infections; Autoimmune Diseases; HIV Infections; Virus Diseases
C-C chemokine receptor type 5 antagonist
Small molecule
Approved
CARDIOVASCULAR; OTHER; RESPIRATORY
ORAL
Anemia, Sickle Cell; Altitude Sickness; Asthma; Hypoplastic Left Heart Syndrome; Severe Acute Respiratory Syndrome; Idiopathic Pulmonary Fibrosis; Vascular Diseases; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension
Endothelin receptor, ET-A/ET-B antagonist
Small molecule
Unknown
Unknown
Unknown
Staphylococcal Infections; Infections; Impetigo
70S ribosome inhibitor
Small molecule
Approved
Unknown
Unknown
Hypertension; Stroke
Renin inhibitor
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Esophageal Neoplasms; Glioma; Multiple Sclerosis; Neoplasms; Schizophrenia; Sleep Initiation and Maintenance Disorders; Stroke; Brain Injuries; Depressive Disorder; Disorders of Excessive Somnolence; Fatigue; Obesity; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Sleep Apnea, Obstructive; Sleep Wake Disorders
Dopamine transporter inhibitor
Small molecule
Approved
OTHER
ORAL
Head and Neck Neoplasms; Paraparesis, Tropical Spastic; Hepatitis C; Leukemia, Biphenotypic, Acute; HTLV-I Infections; Liver Cirrhosis, Biliary; Multiple Sclerosis, Relapsing-Remitting; Acquired Immunodeficiency Syndrome; HIV Infections; Infections; Virus Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Amphetamine-Related Disorders; Cocaine-Related Disorders; Multiple Sclerosis; Bipolar Disorder; Depressive Disorder; Feeding and Eating Disorders; Attention Deficit Disorder with Hyperactivity
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS
ORAL
Pain; Epilepsy; Lennox Gastaut Syndrome; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
HEMATOLOGY; OTHER
ORAL
Myelodysplastic Syndromes; Anemia, Aplastic; Hepatitis C, Chronic; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia
Thrombopoietin receptor agonist
Small molecule
Approved
Unknown
Unknown
Arthritis; Back Pain; Bursitis; Contusions; Muscle Cramp; Myalgia; Pain; Sprains and Strains; Tendinopathy; Wounds and Injuries
Unknown
Small molecule
Approved
Unknown
Unknown
Brain Injuries; Multiple Myeloma; Nasopharyngeal Neoplasms; Genital Neoplasms, Female; Nausea; Neoplasms; Postoperative Nausea and Vomiting
Unknown
Small molecule
Approved
MUSCULOSKELETAL; OTHER
ORAL
Tourette Syndrome; Movement Disorders; Huntington Disease
Synaptic vesicular amine transporter inhibitor
Small molecule
Approved
Unknown
Unknown
Autonomic Dysreflexia; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive; Polyuria; Urinary Incontinence
Unknown
Small molecule
Approved
OTHER
ORAL
Prostatitis; Kidney Calculi; Prostatic Neoplasms, Castration-Resistant; Prostatic Hyperplasia
Alpha-1a adrenergic receptor antagonist
Small molecule
Approved
Unknown
IV (INFUSION)
Hematologic Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Myelodysplastic Syndromes; Amyloidosis, Familial; Breast Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Hairy Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, T-Cell, Peripheral; Multiple Myeloma; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Waldenstrom Macroglobulinemia; Immunoblastic Lymphadenopathy; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Neoplasms
Unknown
Small molecule
Approved
Unknown
ORAL
Back Pain; Chronic Pain; Diabetic Neuropathies; Hallux Valgus; Joint Diseases; Low Back Pain; Neoplasms; Neuralgia; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain
Unknown
Small molecule
Unknown
Unknown
Unknown
Colonic Polyps
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Coronary Disease
Unknown
Small molecule
Unknown
Unknown
Unknown
Fallopian Tube Neoplasms; Ileus; Ovarian Neoplasms; Peritoneal Neoplasms; Urinary Bladder Neoplasms; Constipation
Mu opioid receptor antagonist
Small molecule
Approved
OTHER
ORAL
Fibromyalgia; Hepatitis C, Chronic; Depressive Disorder; Depressive Disorder, Major
Norepinephrine transporter inhibitor
Small molecule
Approved
Unknown
Unknown
Intestinal Obstruction; Kidney Diseases; Liver Diseases; Opioid-Related Disorders; Gastroparesis; Pancreatitis; Constipation; Ileus
Unknown
Small molecule
Approved
Unknown
INTRAVENOUS
Colonic Neoplasms; Rectal Neoplasms; Esophageal Neoplasms; Anemia; Colorectal Neoplasms; Osteosarcoma
Unknown
Small molecule
Approved
CARDIOVASCULAR; OTHER
INTRAVENOUS
Vascular Diseases; Scoliosis; Hypertension; Hypertension, Malignant; Cardiovascular Diseases
Voltage-gated L-type calcium channel blocker
Small molecule
Approved
EYE
OPHTHALMIC
Dry Eye Syndromes; Cataract; Panuveitis; Uveitis; Inflammation; Uveitis, Anterior
Glucocorticoid receptor agonist