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Therapeutic Area
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
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Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
ITX-5061
1
Small molecule
Investigational
Unknown
Unknown
Hepatitis C
Unknown
ITX-5061
×
Maximum Phase:
1
First Approval:
None
UNII:
J4RA8K2Q2A
Molecule Type:
Small molecule
Molecular Formula:
C30H38ClN3O7S
Molecular Weight:
620.17
AlogP:
4.05
PSA:
123.27
HBD:
2.0
HBA:
#RotB:
10.0
Source:
LB-102
1
Small molecule
Investigational
Unknown
Unknown
Schizophrenia
Unknown
LB-102
×
Maximum Phase:
1
First Approval:
None
UNII:
N81WKW91XF
Molecule Type:
Small molecule
Molecular Formula:
C18H29N3O4S
Molecular Weight:
383.51
AlogP:
1.74
PSA:
87.74
HBD:
2.0
HBA:
#RotB:
8.0
Source:
GSK-369796
1
Small molecule
Investigational
Unknown
Unknown
Malaria
Unknown
GSK-369796
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C20H22ClN3O
Molecular Weight:
355.87
AlogP:
5.23
PSA:
57.18
HBD:
3.0
HBA:
#RotB:
4.0
Source:
HKI-357
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HKI-357
×
Maximum Phase:
1
First Approval:
None
UNII:
39R3638KZ6
Molecule Type:
Small molecule
Molecular Formula:
C31H29ClFN5O3
Molecular Weight:
574.06
AlogP:
6.68
PSA:
99.51
HBD:
2.0
HBA:
#RotB:
11.0
Source:
BGT226
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BGT226
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PROPYL GALLATE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PROPYL GALLATE
×
Maximum Phase:
1
First Approval:
None
UNII:
8D4SNN7V92
Molecule Type:
Small molecule
Molecular Formula:
C10H12O5
Molecular Weight:
212.2
AlogP:
1.37
PSA:
86.99
HBD:
3.0
HBA:
#RotB:
3.0
Source:
TELENZEPINE
1
Small molecule
Investigational
Unknown
Unknown
Obesity
Unknown
TELENZEPINE
×
Maximum Phase:
1
First Approval:
None
UNII:
0990EG3K10
Molecule Type:
Small molecule
Molecular Formula:
C19H22N4O2S
Molecular Weight:
370.48
AlogP:
2.53
PSA:
55.89
HBD:
1.0
HBA:
#RotB:
2.0
Source:
ILX23-7553
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Vitamin D receptor agonist
ILX23-7553
×
Maximum Phase:
1
First Approval:
None
UNII:
O13QTC8612
Molecule Type:
Small molecule
Molecular Formula:
C27H38O3
Molecular Weight:
410.6
AlogP:
4.85
PSA:
60.69
HBD:
3.0
HBA:
#RotB:
3.0
Source:
LY2881835
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Free fatty acid receptor 1 agonist
LY2881835
×
Maximum Phase:
1
First Approval:
None
UNII:
LAD0ZG7FFO
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LIFIRAFENIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Serine/threonine-protein kinase B-raf inhibitor
LIFIRAFENIB
×
Maximum Phase:
1
First Approval:
None
UNII:
8762XZS5ZF
Molecule Type:
Small molecule
Molecular Formula:
C25H17F3N4O3
Molecular Weight:
478.43
AlogP:
5.3
PSA:
89.13
HBD:
2.0
HBA:
#RotB:
3.0
Source:
IMD-2560
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
IMD-2560
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BTA-9881
1
Small molecule
Investigational
Unknown
Unknown
Respiratory Syncytial Virus Infections
Unknown
BTA-9881
×
Maximum Phase:
1
First Approval:
None
UNII:
9VR1J6U4XG
Molecule Type:
Small molecule
Molecular Formula:
C21H15ClN4O2
Molecular Weight:
390.83
AlogP:
2.94
PSA:
66.4
HBD:
0.0
HBA:
#RotB:
2.0
Source:
DELANZOMIB
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin; Multiple Myeloma
Unknown
DELANZOMIB
×
Maximum Phase:
1
First Approval:
None
UNII:
6IF28942WO
Molecule Type:
Small molecule
Molecular Formula:
C21H28BN3O5
Molecular Weight:
413.28
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
BMS-214662
1
Small molecule
Investigational
Unknown
Unknown
Anemia, Refractory, with Excess of Blasts; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Unknown
BMS-214662
×
Maximum Phase:
1
First Approval:
None
UNII:
L2U9GFD244
Molecule Type:
Small molecule
Molecular Formula:
C25H23N5O2S2
Molecular Weight:
489.63
AlogP:
4.17
PSA:
93.09
HBD:
1.0
HBA:
#RotB:
6.0
Source:
FENAMIC ACID
1
Small molecule
Investigational
Unknown
Unknown
Pancreatic Neoplasms
Unknown
FENAMIC ACID
×
Maximum Phase:
1
First Approval:
None
UNII:
952VN06WBB
Molecule Type:
Small molecule
Molecular Formula:
C13H11NO2
Molecular Weight:
213.24
AlogP:
3.13
PSA:
49.33
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PLX8394
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PLX8394
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
EPZ-5676
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
EPZ-5676
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LISAVANBULIN
1
Small molecule
Investigational
Unknown
Unknown
Glioblastoma; Neoplasms
Unknown
LISAVANBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
5PT0QP06X5
Molecule Type:
Small molecule
Molecular Formula:
C26H29N9O3
Molecular Weight:
515.58
AlogP:
2.69
PSA:
190.77
HBD:
4.0
HBA:
#RotB:
13.0
Source:
HYPERICIN
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections; Lymphoma, T-Cell, Cutaneous
Unknown
HYPERICIN
×
Maximum Phase:
1
First Approval:
None
UNII:
7V2F1075HD
Molecule Type:
Small molecule
Molecular Formula:
C30H16O8
Molecular Weight:
504.45
AlogP:
5.08
PSA:
155.52
HBD:
6.0
HBA:
#RotB:
0.0
Source:
RG7893
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Sodium channel protein type IX alpha subunit blocker
RG7893
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK159802
1
Small molecule
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
GSK159802
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CIS-UROCANIC ACID
1
Small molecule
Investigational
Unknown
Unknown
Dry Eye Syndromes
Unknown
CIS-UROCANIC ACID
×
Maximum Phase:
1
First Approval:
None
UNII:
5LM7WD7VIC
Molecule Type:
Small molecule
Molecular Formula:
C6H6N2O2
Molecular Weight:
138.13
AlogP:
0.51
PSA:
65.98
HBD:
2.0
HBA:
#RotB:
2.0
Source:
E7107
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
E7107
×
Maximum Phase:
1
First Approval:
None
UNII:
R60DZX1E2N
Molecule Type:
Small molecule
Molecular Formula:
C40H66N2O9
Molecular Weight:
718.97
AlogP:
5.05
PSA:
152.53
HBD:
4.0
HBA:
#RotB:
10.0
Source:
VLX-1005
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
VLX-1005
×
Maximum Phase:
1
First Approval:
None
UNII:
JKU4XCC48Y
Molecule Type:
Small molecule
Molecular Formula:
C21H19N3O4S2
Molecular Weight:
441.53
AlogP:
4.42
PSA:
100.55
HBD:
3.0
HBA:
#RotB:
7.0
Source:
SIBOFIMLOC
1
Small molecule
Investigational
Unknown
Unknown
Crohn Disease
Unknown
SIBOFIMLOC
×
Maximum Phase:
1
First Approval:
None
UNII:
00OF00QZC4
Molecule Type:
Small molecule
Molecular Formula:
C35H39NO11
Molecular Weight:
649.69
AlogP:
-2.02
PSA:
200.61
HBD:
8.0
HBA:
#RotB:
2.0
Source:
RALANITEN ACETATE
1
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms
Unknown
RALANITEN ACETATE
×
Maximum Phase:
1
First Approval:
None
UNII:
L10K286T2H
Molecule Type:
Small molecule
Molecular Formula:
C27H33ClO8
Molecular Weight:
521.01
AlogP:
4.44
PSA:
97.36
HBD:
0.0
HBA:
#RotB:
13.0
Source:
HYODEOXYCHOLIC_ACID
1
Small molecule
Investigational
Unknown
Unknown
Hypercholesterolemia
LXR-alpha agonist
HYODEOXYCHOLIC_ACID
×
Maximum Phase:
1
First Approval:
None
UNII:
7A33Y6EHYK
Molecule Type:
Small molecule
Molecular Formula:
C24H40O4
Molecular Weight:
392.58
AlogP:
4.48
PSA:
77.76
HBD:
3.0
HBA:
#RotB:
4.0
Source:
QC-12
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
QC-12
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PF-114
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Unknown
PF-114
×
Maximum Phase:
1
First Approval:
None
UNII:
I8C3R768IZ
Molecule Type:
Small molecule
Molecular Formula:
C29H27F3N6O
Molecular Weight:
532.57
AlogP:
4.46
PSA:
65.77
HBD:
1.0
HBA:
#RotB:
4.0
Source:
ALTIRATINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Hepatocyte growth factor receptor inhibitor
ALTIRATINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
T678746713
Molecule Type:
Small molecule
Molecular Formula:
C26H21F3N4O4
Molecular Weight:
510.47
AlogP:
5.0
PSA:
109.42
HBD:
3.0
HBA:
#RotB:
8.0
Source:
AZELOPRAZOLE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AZELOPRAZOLE
×
Maximum Phase:
1
First Approval:
None
UNII:
MIR2G6L61B
Molecule Type:
Small molecule
Molecular Formula:
C22H27N3O4S
Molecular Weight:
429.54
AlogP:
3.66
PSA:
86.33
HBD:
1.0
HBA:
#RotB:
6.0
Source:
ZOTATIFIN
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Severe Acute Respiratory Syndrome
Unknown
ZOTATIFIN
×
Maximum Phase:
1
First Approval:
None
UNII:
2EWN8Z05CN
Molecule Type:
Small molecule
Molecular Formula:
C28H29N3O5
Molecular Weight:
487.56
AlogP:
2.78
PSA:
108.07
HBD:
2.0
HBA:
#RotB:
6.0
Source:
RODATRISTAT ETHYL
1
Small molecule
Investigational
Unknown
Unknown
Hypertension, Pulmonary
Tryptophan 5-hydroxylase 1 inhibitor
RODATRISTAT ETHYL
×
Maximum Phase:
1
First Approval:
None
UNII:
507FY6OL37
Molecule Type:
Small molecule
Molecular Formula:
C29H31ClF3N5O3
Molecular Weight:
590.05
AlogP:
5.57
PSA:
102.6
HBD:
2.0
HBA:
#RotB:
7.0
Source:
VINPOCETINE
1
Small molecule
Investigational
Unknown
Unknown
Epilepsy; Attention Deficit Disorder with Hyperactivity
Unknown
VINPOCETINE
×
Maximum Phase:
1
First Approval:
None
UNII:
543512OBTC
Molecule Type:
Small molecule
Molecular Formula:
C22H26N2O2
Molecular Weight:
350.46
AlogP:
4.15
PSA:
34.47
HBD:
0.0
HBA:
#RotB:
3.0
Source:
PYRUVATE SODIUM
1
Small molecule
Investigational
Unknown
Unknown
Asthma; Cystic Fibrosis
Unknown
PYRUVATE SODIUM
×
Maximum Phase:
1
First Approval:
None
UNII:
POD38AIF08
Molecule Type:
Small molecule
Molecular Formula:
C3H3NaO3
Molecular Weight:
110.04
AlogP:
-0.34
PSA:
54.37
HBD:
1.0
HBA:
#RotB:
1.0
Source:
1
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Compound Name
Maximum Phase
Compound Structure
Smile
Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA