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EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
NT-219
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NT-219
×
Maximum Phase:
1
First Approval:
None
UNII:
K1WT1A1UP5
Molecule Type:
Small molecule
Molecular Formula:
C16H14BrNO5S
Molecular Weight:
412.26
AlogP:
3.11
PSA:
113.18
HBD:
6.0
HBA:
#RotB:
4.0
Source:
DIINDOLYLMETHANE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
DIINDOLYLMETHANE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IRSOGLADINE MALEATE
1
Small molecule
Investigational
Unknown
Unknown
Gastritis; Peptic Ulcer; Stomach Ulcer
Unknown
IRSOGLADINE MALEATE
×
Maximum Phase:
1
First Approval:
None
UNII:
66GVU60EPQ
Molecule Type:
Small molecule
Molecular Formula:
C13H11Cl2N5O4
Molecular Weight:
372.17
AlogP:
2.01
PSA:
90.71
HBD:
2.0
HBA:
#RotB:
1.0
Source:
FK453
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Adenosine A1 receptor antagonist
FK453
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C23H25N3O2
Molecular Weight:
375.47
AlogP:
3.78
PSA:
57.84
HBD:
1.0
HBA:
#RotB:
5.0
Source:
ALOFANIB
1
Small molecule
Investigational
Unknown
Unknown
Stomach Neoplasms
Unknown
ALOFANIB
×
Maximum Phase:
1
First Approval:
None
UNII:
LQX7RFK8MZ
Molecule Type:
Small molecule
Molecular Formula:
C19H15N3O6S
Molecular Weight:
413.41
AlogP:
3.46
PSA:
139.5
HBD:
2.0
HBA:
#RotB:
6.0
Source:
KPT-8602
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
KPT-8602
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD8108
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Glutamate [NMDA] receptor antagonist
AZD8108
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CH5132799
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CH5132799
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CROCETIN
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CROCETIN
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MK-1064
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MK-1064
×
Maximum Phase:
1
First Approval:
None
UNII:
O812716S9E
Molecule Type:
Small molecule
Molecular Formula:
C24H20ClN5O3
Molecular Weight:
461.91
AlogP:
4.2
PSA:
99.12
HBD:
1.0
HBA:
#RotB:
7.0
Source:
CPI-1205
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Follicular; Neoplasms; Prostatic Neoplasms, Castration-Resistant
Unknown
CPI-1205
×
Maximum Phase:
1
First Approval:
None
UNII:
455J2479FY
Molecule Type:
Small molecule
Molecular Formula:
C27H33F3N4O3
Molecular Weight:
518.58
AlogP:
4.72
PSA:
79.36
HBD:
2.0
HBA:
#RotB:
7.0
Source:
XL-888
1
Small molecule
Investigational
Unknown
Unknown
Melanoma; Neoplasms; Skin Neoplasms
Unknown
XL-888
×
Maximum Phase:
1
First Approval:
None
UNII:
7M346920EV
Molecule Type:
Small molecule
Molecular Formula:
C29H37N5O3
Molecular Weight:
503.65
AlogP:
4.22
PSA:
117.42
HBD:
3.0
HBA:
#RotB:
9.0
Source:
BPN-14967
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BPN-14967
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SNS-062
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SNS-062
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MK-2201
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Serine/threonine-protein kinase AKT inhibitor
MK-2201
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MMV-390048
1
Small molecule
Investigational
Unknown
Unknown
Malaria; Malaria, Falciparum
Unknown
MMV-390048
×
Maximum Phase:
1
First Approval:
None
UNII:
0Z5T00JJ10
Molecule Type:
Small molecule
Molecular Formula:
C18H14F3N3O2S
Molecular Weight:
393.39
AlogP:
3.82
PSA:
85.94
HBD:
1.0
HBA:
#RotB:
3.0
Source:
TTP-607
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma; Neoplasms
Serine/threonine-protein kinase Aurora inhibitor
TTP-607
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
XANTHOHUMOL
1
Small molecule
Investigational
Unknown
Unknown
Crohn Disease
Unknown
XANTHOHUMOL
×
Maximum Phase:
1
First Approval:
None
UNII:
T4467YT1NT
Molecule Type:
Small molecule
Molecular Formula:
C21H22O5
Molecular Weight:
354.4
AlogP:
4.22
PSA:
86.99
HBD:
3.0
HBA:
#RotB:
6.0
Source:
GMI-1271
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GMI-1271
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAK-593
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Platelet-derived growth factor receptor inhibitor
TAK-593
×
Maximum Phase:
1
First Approval:
None
UNII:
H3I42X8XX7
Molecule Type:
Small molecule
Molecular Formula:
C23H23N7O3
Molecular Weight:
445.48
AlogP:
3.47
PSA:
115.44
HBD:
2.0
HBA:
#RotB:
6.0
Source:
AR-12
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma
3-phosphoinositide dependent protein kinase-1 inhibitor
AR-12
×
Maximum Phase:
1
First Approval:
None
UNII:
EX3O2Q61UV
Molecule Type:
Small molecule
Molecular Formula:
C26H19F3N4O
Molecular Weight:
460.46
AlogP:
5.76
PSA:
72.94
HBD:
2.0
HBA:
#RotB:
4.0
Source:
PHENFORMIN
1
Small molecule
Investigational
Unknown
Unknown
Melanoma; Diabetes Mellitus
Unknown
PHENFORMIN
×
Maximum Phase:
1
First Approval:
None
UNII:
DD5K7529CE
Molecule Type:
Small molecule
Molecular Formula:
C10H15N5
Molecular Weight:
205.26
AlogP:
0.24
PSA:
97.78
HBD:
5.0
HBA:
#RotB:
3.0
Source:
HEMAY-022
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms
Receptor protein-tyrosine kinase erbB-2 inhibitor
HEMAY-022
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PWT-33579
1
Small molecule
Investigational
Unknown
Unknown
Unknown
PI3-kinase p110-alpha subunit inhibitor
PWT-33579
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MIP-1095 I-123
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MIP-1095 I-123
×
Maximum Phase:
1
First Approval:
None
UNII:
HD4940602J
Molecule Type:
Small molecule
Molecular Formula:
C19H25IN4O8
Molecular Weight:
560.33
AlogP:
1.65
PSA:
194.16
HBD:
7.0
HBA:
#RotB:
13.0
Source:
VT-1598
1
Small molecule
Investigational
Unknown
Unknown
Coccidioidomycosis
Unknown
VT-1598
×
Maximum Phase:
1
First Approval:
None
UNII:
AV9K9X720D
Molecule Type:
Small molecule
Molecular Formula:
C31H20F4N6O2
Molecular Weight:
584.53
AlogP:
4.88
PSA:
109.74
HBD:
1.0
HBA:
#RotB:
8.0
Source:
FLUOROACETATE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FLUOROACETATE
×
Maximum Phase:
1
First Approval:
None
UNII:
AP1JV9U41M
Molecule Type:
Small molecule
Molecular Formula:
C2H3FO2
Molecular Weight:
78.04
AlogP:
0.04
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
1.0
Source:
N-METHANOCARBATHYMIDINE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
N-METHANOCARBATHYMIDINE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RO-4987655
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
RO-4987655
×
Maximum Phase:
1
First Approval:
None
UNII:
I3733P75ML
Molecule Type:
Small molecule
Molecular Formula:
C20H19F3IN3O5
Molecular Weight:
565.29
AlogP:
3.16
PSA:
100.13
HBD:
3.0
HBA:
#RotB:
8.0
Source:
(R)-IBUPROPHEN
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
(R)-IBUPROPHEN
×
Maximum Phase:
1
First Approval:
None
UNII:
99W8H60N62
Molecule Type:
Small molecule
Molecular Formula:
C13H18O2
Molecular Weight:
206.28
AlogP:
3.07
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
4.0
Source:
RO-3201195
1
Small molecule
Investigational
Unknown
Unknown
Unknown
MAP kinase p38 alpha inhibitor
RO-3201195
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C19H18FN3O4
Molecular Weight:
371.37
AlogP:
1.56
PSA:
110.6
HBD:
3.0
HBA:
#RotB:
7.0
Source:
RELACATIB
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
RELACATIB
×
Maximum Phase:
1
First Approval:
None
UNII:
BL51M8CB8R
Molecule Type:
Small molecule
Molecular Formula:
C27H32N4O6S
Molecular Weight:
540.64
AlogP:
2.9
PSA:
138.68
HBD:
2.0
HBA:
#RotB:
8.0
Source:
FRUCTOSE
1
Small molecule
Investigational
Unknown
Unknown
Hypoglycemia; Melanoma; Non-alcoholic Fatty Liver Disease; Obesity
Unknown
FRUCTOSE
×
Maximum Phase:
1
First Approval:
None
UNII:
B986VTP17J
Molecule Type:
Small molecule
Molecular Formula:
C6H12O6
Molecular Weight:
180.16
AlogP:
-3.22
PSA:
110.38
HBD:
5.0
HBA:
#RotB:
2.0
Source:
UNESBULIN
1
Small molecule
Investigational
Unknown
Unknown
Diffuse Intrinsic Pontine Glioma; Leiomyosarcoma; Neoplasms; Ovarian Neoplasms
Unknown
UNESBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
Z4HZ70S62Q
Molecule Type:
Small molecule
Molecular Formula:
C19H13F5N6
Molecular Weight:
420.35
AlogP:
4.75
PSA:
81.65
HBD:
2.0
HBA:
#RotB:
3.0
Source:
HSD-016
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HSD-016
×
Maximum Phase:
1
First Approval:
None
UNII:
C4I13768E1
Molecule Type:
Small molecule
Molecular Formula:
C21H21F7N2O3S
Molecular Weight:
514.46
AlogP:
4.51
PSA:
60.85
HBD:
1.0
HBA:
#RotB:
4.0
Source:
1
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89
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Header
Compound Name
Maximum Phase
Compound Structure
Smile
Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA