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Therapeutic Area
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
EXEPORFINIUM
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
EXEPORFINIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
R41ECT47G6
Molecule Type:
Small molecule
Molecular Formula:
C44H50N6O2+2
Molecular Weight:
694.92
AlogP:
8.94
PSA:
75.82
HBD:
2.0
HBA:
#RotB:
12.0
Source:
PEXACERFONT
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major; Anxiety Disorders; Irritable Bowel Syndrome
Corticotropin releasing factor receptor 1 antagonist
PEXACERFONT
×
Maximum Phase:
2
First Approval:
None
UNII:
LF1VBG4ZUK
Molecule Type:
Small molecule
Molecular Formula:
C18H24N6O
Molecular Weight:
340.43
AlogP:
3.33
PSA:
77.23
HBD:
1.0
HBA:
#RotB:
5.0
Source:
LAS100977
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LAS100977
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
C-1311
2
Small molecule
Investigational
Unknown
Unknown
Unknown
DNA topoisomerase II inhibitor
C-1311
×
Maximum Phase:
2
First Approval:
None
UNII:
MZ4Y5H4OAB
Molecule Type:
Small molecule
Molecular Formula:
C20H22N4O2
Molecular Weight:
350.42
AlogP:
2.9
PSA:
69.87
HBD:
2.0
HBA:
#RotB:
6.0
Source:
ILACIRNON
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerulosclerosis, Focal Segmental
C-C chemokine receptor type 2 antagonist
ILACIRNON
×
Maximum Phase:
2
First Approval:
None
UNII:
380F68J5PH
Molecule Type:
Small molecule
Molecular Formula:
C20H13ClF3N5O3S
Molecular Weight:
495.87
AlogP:
4.37
PSA:
117.7
HBD:
2.0
HBA:
#RotB:
5.0
Source:
AR-12286
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AR-12286
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAS-109
2
Small molecule
Investigational
Unknown
Unknown
Colorectal Neoplasms
Unknown
TAS-109
×
Maximum Phase:
2
First Approval:
None
UNII:
00M634HD2V
Molecule Type:
Small molecule
Molecular Formula:
C10H12N4O4
Molecular Weight:
252.23
AlogP:
-1.78
PSA:
134.39
HBD:
3.0
HBA:
#RotB:
2.0
Source:
BBV-152 ANTIGEN ADJUVATED WITH ALGEL-IMDG
2
Unknown
Investigational
Unknown
Unknown
Severe Acute Respiratory Syndrome
Unknown
BBV-152 ANTIGEN ADJUVATED WITH ALGEL-IMDG
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HEMIN
2
Small molecule
Investigational
Unknown
Unknown
Coproporphyria, Hereditary; Myelodysplastic Syndromes; Pancreatitis; Porphyria, Acute Intermittent; Porphyrias
Unknown
HEMIN
×
Maximum Phase:
2
First Approval:
None
UNII:
743LRP9S7N
Molecule Type:
Small molecule
Molecular Formula:
C34H32ClFeN4O4
Molecular Weight:
651.95
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
MT-3724
2
Unknown
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin
80S Ribosome inhibitor
MT-3724
×
Maximum Phase:
2
First Approval:
None
UNII:
R23ZRN6GWR
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SULFORAPHANE
2
Small molecule
Investigational
Unknown
Unknown
Melanoma; Skin Aging; Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Aging; Child Development Disorders, Pervasive; Depressive Disorder; Diabetes Mellitus, Type 2; Lung Neoplasms; Prostatic Neoplasms; Psychotic Disorders; Schizophrenia; Autistic Disorder
Unknown
SULFORAPHANE
×
Maximum Phase:
2
First Approval:
None
UNII:
41684WL1GL
Molecule Type:
Small molecule
Molecular Formula:
C6H11NOS2
Molecular Weight:
177.29
AlogP:
1.25
PSA:
29.43
HBD:
0.0
HBA:
#RotB:
5.0
Source:
NVN1000
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NVN1000
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PIPERINE
2
Small molecule
Investigational
Unknown
Unknown
Deglutition Disorders; Pain
Unknown
PIPERINE
×
Maximum Phase:
2
First Approval:
None
UNII:
U71XL721QK
Molecule Type:
Small molecule
Molecular Formula:
C17H19NO3
Molecular Weight:
285.34
AlogP:
3.0
PSA:
38.77
HBD:
0.0
HBA:
#RotB:
3.0
Source:
3,5-DIIODOTHYROPROPIONIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Hypercholesterolemia; Heart Failure
Unknown
3,5-DIIODOTHYROPROPIONIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
1HTO2X0SJ9
Molecule Type:
Small molecule
Molecular Formula:
C15H12I2O4
Molecular Weight:
510.07
AlogP:
4.41
PSA:
66.76
HBD:
2.0
HBA:
#RotB:
5.0
Source:
HBM9161
2
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
HBM9161
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LY2624803
2
Small molecule
Investigational
Unknown
Unknown
Sleep Initiation and Maintenance Disorders
Histamine H1 receptor antagonist
LY2624803
×
Maximum Phase:
2
First Approval:
None
UNII:
63J9EQ81YC
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LY3016859
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LY3016859
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TIRABRUTINIB
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Sjogren's Syndrome; Urticaria
Tyrosine-protein kinase BTK inhibitor
TIRABRUTINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
LXG44NDL2T
Molecule Type:
Small molecule
Molecular Formula:
C25H22N6O3
Molecular Weight:
454.49
AlogP:
2.75
PSA:
108.27
HBD:
1.0
HBA:
#RotB:
4.0
Source:
GTX-758
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Estrogen receptor alpha agonist
GTX-758
×
Maximum Phase:
2
First Approval:
None
UNII:
406GR1485Z
Molecule Type:
Small molecule
Molecular Formula:
C19H13F2NO3
Molecular Weight:
341.31
AlogP:
4.35
PSA:
60.77
HBD:
2.0
HBA:
#RotB:
3.0
Source:
CENERIMOD
2
Small molecule
Investigational
Unknown
Unknown
Liver Diseases; Lupus Erythematosus, Systemic
Sphingosine 1-phosphate receptor Edg-1 modulator
CENERIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
Y333RS1786
Molecule Type:
Small molecule
Molecular Formula:
C25H31N3O5
Molecular Weight:
453.54
AlogP:
4.07
PSA:
110.73
HBD:
2.0
HBA:
#RotB:
9.0
Source:
CX-072
2
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
CX-072
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HUMAN C-PEPTIDE
2
Protein
Investigational
Unknown
Unknown
Unknown
Unknown
HUMAN C-PEPTIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
O2J76Y002M
Molecule Type:
Protein
Molecular Formula:
C129H211N35O48
Molecular Weight:
3020.3
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
ENCALERET
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ENCALERET
×
Maximum Phase:
2
First Approval:
None
UNII:
EF8081AQ6G
Molecule Type:
Small molecule
Molecular Formula:
C29H33ClFNO4
Molecular Weight:
514.04
AlogP:
6.2
PSA:
78.79
HBD:
3.0
HBA:
#RotB:
11.0
Source:
AZD-8871
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AZD-8871
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TRAXOPRODIL
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major; Parkinson Disease; Stroke
Glutamate NMDA receptor; GRIN1/GRIN2B antagonist
TRAXOPRODIL
×
Maximum Phase:
2
First Approval:
None
UNII:
UTC046R5HM
Molecule Type:
Small molecule
Molecular Formula:
C20H25NO3
Molecular Weight:
327.42
AlogP:
2.8
PSA:
63.93
HBD:
3.0
HBA:
#RotB:
4.0
Source:
INO-1001
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
INO-1001
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ABX-1431
2
Small molecule
Investigational
Unknown
Unknown
Dyspepsia; Pain; Tourette Syndrome
Monoglyceride lipase inhibitor
ABX-1431
×
Maximum Phase:
2
First Approval:
None
UNII:
FB39E94UXK
Molecule Type:
Small molecule
Molecular Formula:
C20H22F9N3O2
Molecular Weight:
507.4
AlogP:
5.05
PSA:
36.02
HBD:
0.0
HBA:
#RotB:
4.0
Source:
CIPARGAMIN
2
Small molecule
Investigational
Unknown
Unknown
Malaria, Falciparum; Malaria
P-type ATPase inhibitor
CIPARGAMIN
×
Maximum Phase:
2
First Approval:
None
UNII:
Z7Q4FWA04P
Molecule Type:
Small molecule
Molecular Formula:
C19H14Cl2FN3O
Molecular Weight:
390.25
AlogP:
4.34
PSA:
56.92
HBD:
3.0
HBA:
#RotB:
0.0
Source:
DEOXYSPERGUALIN
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
DEOXYSPERGUALIN
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD6765
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AZD6765
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
QAX576
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
QAX576
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TALNETANT
2
Small molecule
Investigational
Unknown
Unknown
Irritable Bowel Syndrome; Schizophrenia
Neurokinin 3 receptor antagonist
TALNETANT
×
Maximum Phase:
2
First Approval:
None
UNII:
CZ3T9T146K
Molecule Type:
Small molecule
Molecular Formula:
C25H22N2O2
Molecular Weight:
382.46
AlogP:
5.49
PSA:
62.22
HBD:
2.0
HBA:
#RotB:
5.0
Source:
GLPG-0974
2
Small molecule
Investigational
Unknown
Unknown
Colitis, Ulcerative
Free fatty acid receptor 2 antagonist
GLPG-0974
×
Maximum Phase:
2
First Approval:
None
UNII:
X7REK61AIS
Molecule Type:
Small molecule
Molecular Formula:
C25H25ClN2O4S
Molecular Weight:
485.01
AlogP:
5.05
PSA:
77.92
HBD:
1.0
HBA:
#RotB:
8.0
Source:
ACT-709478
2
Small molecule
Investigational
Unknown
Unknown
Epilepsy, Reflex
Voltage-gated T-type calcium channel blocker
ACT-709478
×
Maximum Phase:
2
First Approval:
None
UNII:
3Z7U1U8Z9E
Molecule Type:
Small molecule
Molecular Formula:
C22H18F3N5O
Molecular Weight:
425.41
AlogP:
3.97
PSA:
83.6
HBD:
1.0
HBA:
#RotB:
6.0
Source:
MEDI-507
2
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
MEDI-507
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
1
2
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136
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138
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Compound Name
Maximum Phase
Compound Structure
Smile
Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA