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DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
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Level 2
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
RADAFAXINE
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major
Unknown
RADAFAXINE
×
Maximum Phase:
2
First Approval:
None
UNII:
Q47741214K
Molecule Type:
Small molecule
Molecular Formula:
C13H18ClNO2
Molecular Weight:
255.74
AlogP:
2.27
PSA:
41.49
HBD:
2.0
HBA:
#RotB:
1.0
Source:
PIDOLIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PIDOLIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
SZB83O1W42
Molecule Type:
Small molecule
Molecular Formula:
C5H7NO3
Molecular Weight:
129.12
AlogP:
-0.65
PSA:
66.4
HBD:
2.0
HBA:
#RotB:
1.0
Source:
TENATUMOMAB
2
Antibody
Investigational
Unknown
Unknown
Unknown
Tenascin other
TENATUMOMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
7C201CLB71
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ONCOLYSIN S
2
Antibody
Investigational
Unknown
Unknown
Unknown
Neural cell adhesion molecule 1 binding agent
ONCOLYSIN S
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SRT-2104
2
Small molecule
Investigational
Unknown
Unknown
Atrophy; Colitis, Ulcerative; Muscular Atrophy; Pulmonary Disease, Chronic Obstructive; Sepsis; Diabetes Mellitus, Type 2; Psoriasis
NAD-dependent deacetylase sirtuin 1 activator
SRT-2104
×
Maximum Phase:
2
First Approval:
None
UNII:
4521NR0J09
Molecule Type:
Small molecule
Molecular Formula:
C26H24N6O2S2
Molecular Weight:
516.65
AlogP:
4.97
PSA:
84.65
HBD:
1.0
HBA:
#RotB:
6.0
Source:
BUDIODARONE
2
Small molecule
Investigational
Unknown
Unknown
Atrial Fibrillation
Unknown
BUDIODARONE
×
Maximum Phase:
2
First Approval:
None
UNII:
F5Y53150C8
Molecule Type:
Small molecule
Molecular Formula:
C27H31I2NO5
Molecular Weight:
703.35
AlogP:
6.48
PSA:
68.98
HBD:
0.0
HBA:
#RotB:
12.0
Source:
13-DEOXYDOXORUBICIN
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
13-DEOXYDOXORUBICIN
×
Maximum Phase:
2
First Approval:
None
UNII:
1S9VO1DQG5
Molecule Type:
Small molecule
Molecular Formula:
C27H31NO10
Molecular Weight:
529.54
AlogP:
0.82
PSA:
189.0
HBD:
6.0
HBA:
#RotB:
5.0
Source:
PEGVORHYALURONIDASE ALFA
2
Enzyme
Investigational
Unknown
Unknown
Cholangiocarcinoma; Esophageal Neoplasms; Neoplasms; Stomach Neoplasms; Adenocarcinoma; Carcinoma, Pancreatic Ductal; Pancreatic Neoplasms
Hyaluronic acid hydrolytic enzyme
PEGVORHYALURONIDASE ALFA
×
Maximum Phase:
2
First Approval:
None
UNII:
P01I4980ZS
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BLESELUMAB
2
Antibody
Investigational
Unknown
Unknown
Glomerulosclerosis, Focal Segmental; Psoriasis
Tumor necrosis factor receptor superfamily member 5 inhibitor
BLESELUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
AS3AZ5R46K
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OROTIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
OROTIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
61H4T033E5
Molecule Type:
Small molecule
Molecular Formula:
C5H4N2O4
Molecular Weight:
156.1
AlogP:
-1.24
PSA:
103.02
HBD:
3.0
HBA:
#RotB:
1.0
Source:
TERN-101
2
Unknown
Investigational
Unknown
Unknown
Non-alcoholic Fatty Liver Disease
Bile acid receptor FXR agonist
TERN-101
×
Maximum Phase:
2
First Approval:
None
UNII:
VVA2ZDV3LX
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HORSE CHESTNUT
2
Unknown
Investigational
Unknown
Unknown
Lymphedema
Unknown
HORSE CHESTNUT
×
Maximum Phase:
2
First Approval:
None
UNII:
3C18L6RJAZ
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ASTEGOLIMAB
2
Antibody
Investigational
Unknown
Unknown
Asthma; Dermatitis, Atopic; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome
Unknown
ASTEGOLIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
27TW751DTH
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LCV
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LCV
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DEXPRAMIPEXOLE DIHYDROCHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Amyotrophic Lateral Sclerosis
Unknown
DEXPRAMIPEXOLE DIHYDROCHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
795J01AE70
Molecule Type:
Small molecule
Molecular Formula:
C10H21Cl2N3OS
Molecular Weight:
302.27
AlogP:
1.58
PSA:
50.94
HBD:
2.0
HBA:
#RotB:
3.0
Source:
IMSIDOLIMAB
2
Antibody
Investigational
Unknown
Unknown
Acneiform Eruptions; Acne Vulgaris; Hidradenitis Suppurativa; Ichthyosis; Psoriasis
IL36 receptor antagonist
IMSIDOLIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-813160
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Pancreatic Ductal; Hyperplasia; Diabetic Nephropathies; Neoplasms
C-C chemokine receptor type 2 antagonist
BMS-813160
×
Maximum Phase:
2
First Approval:
None
UNII:
83U7957287
Molecule Type:
Small molecule
Molecular Formula:
C25H40N8O2
Molecular Weight:
484.65
AlogP:
2.25
PSA:
116.55
HBD:
3.0
HBA:
#RotB:
5.0
Source:
DEOXYCYTIDINE
2
Small molecule
Investigational
Unknown
Unknown
Leukemia; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms
Unknown
DEOXYCYTIDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
0W860991D6
Molecule Type:
Small molecule
Molecular Formula:
C9H13N3O4
Molecular Weight:
227.22
AlogP:
-1.53
PSA:
110.6
HBD:
3.0
HBA:
#RotB:
2.0
Source:
GSK2798745
2
Small molecule
Investigational
Unknown
Unknown
Cough; Macular Edema; Heart Failure; Pulmonary Edema
Transient receptor potential cation channel subfamily V member 4 antagonist
GSK2798745
×
Maximum Phase:
2
First Approval:
None
UNII:
63FJ7LF55O
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AFP-464
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Breast Neoplasms
Unknown
AFP-464
×
Maximum Phase:
2
First Approval:
None
UNII:
73JNH95XPX
Molecule Type:
Small molecule
Molecular Formula:
C26H35F3N4O9S2
Molecular Weight:
668.71
AlogP:
3.94
PSA:
137.37
HBD:
4.0
HBA:
#RotB:
9.0
Source:
RN6G
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
RN6G
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TANSHINONE IIA SULFONATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
TANSHINONE IIA SULFONATE
×
Maximum Phase:
2
First Approval:
None
UNII:
5CKR8JG9OW
Molecule Type:
Small molecule
Molecular Formula:
C19H17NaO6S
Molecular Weight:
396.4
AlogP:
3.49
PSA:
101.65
HBD:
1.0
HBA:
#RotB:
1.0
Source:
Q203
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
Q203
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-3759
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
AZD-3759
×
Maximum Phase:
2
First Approval:
None
UNII:
67SX9H68W2
Molecule Type:
Small molecule
Molecular Formula:
C22H23ClFN5O3
Molecular Weight:
459.91
AlogP:
4.31
PSA:
79.82
HBD:
1.0
HBA:
#RotB:
4.0
Source:
MIRAMISTIN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MIRAMISTIN
×
Maximum Phase:
2
First Approval:
None
UNII:
QL5J8F55LH
Molecule Type:
Small molecule
Molecular Formula:
C26H47ClN2O
Molecular Weight:
439.13
AlogP:
6.47
PSA:
29.1
HBD:
1.0
HBA:
#RotB:
18.0
Source:
MIBAMPATOR
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Glutamate receptor ionotropic AMPA positive allosteric modulator
MIBAMPATOR
×
Maximum Phase:
2
First Approval:
None
UNII:
A9V5BW73UU
Molecule Type:
Small molecule
Molecular Formula:
C21H30N2O4S2
Molecular Weight:
438.62
AlogP:
2.88
PSA:
92.34
HBD:
2.0
HBA:
#RotB:
10.0
Source:
INCLACUMAB
2
Antibody
Investigational
Unknown
Unknown
Peripheral Arterial Disease; Coronary Disease; Myocardial Infarction
P-selectin antagonist
INCLACUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
A6734I702L
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INODIFTAGENE VIXTEPLASMID
2
Gene
Investigational
Unknown
Unknown
Urinary Bladder Neoplasms
Unknown
INODIFTAGENE VIXTEPLASMID
×
Maximum Phase:
2
First Approval:
None
UNII:
98YK326XZ6
Molecule Type:
Gene
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VIPIVOTIDE TETRAXETAN GALLIUM GA-68
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Unknown
VIPIVOTIDE TETRAXETAN GALLIUM GA-68
×
Maximum Phase:
2
First Approval:
None
UNII:
7P5C02S4X8
Molecule Type:
Small molecule
Molecular Formula:
C49H68GaN9O16
Molecular Weight:
1107.06
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
POLYDEXTROSE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
POLYDEXTROSE
×
Maximum Phase:
2
First Approval:
None
UNII:
VH2XOU12IE
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
WNT-974
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Squamous Cell
Probable protein-cysteine N-palmitoyltransferase porcupine inhibitor
WNT-974
×
Maximum Phase:
2
First Approval:
None
UNII:
U27F40013Q
Molecule Type:
Small molecule
Molecular Formula:
C23H20N6O
Molecular Weight:
396.45
AlogP:
3.79
PSA:
93.55
HBD:
1.0
HBA:
#RotB:
5.0
Source:
LY-2090314
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Pancreatic Neoplasms; Leukemia
Glycogen synthase kinase-3 alpha inhibitor
LY-2090314
×
Maximum Phase:
2
First Approval:
None
UNII:
822M3GYM67
Molecule Type:
Small molecule
Molecular Formula:
C28H25FN6O3
Molecular Weight:
512.55
AlogP:
3.42
PSA:
91.95
HBD:
1.0
HBA:
#RotB:
2.0
Source:
JNJ-41443532
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
C-C chemokine receptor type 2 antagonist
JNJ-41443532
×
Maximum Phase:
2
First Approval:
None
UNII:
0OJB0LES1A
Molecule Type:
Small molecule
Molecular Formula:
C22H25F3N4O3S
Molecular Weight:
482.53
AlogP:
2.52
PSA:
94.56
HBD:
3.0
HBA:
#RotB:
6.0
Source:
ORM-12741
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Unknown
ORM-12741
×
Maximum Phase:
2
First Approval:
None
UNII:
D26C95A960
Molecule Type:
Small molecule
Molecular Formula:
C18H23NO2
Molecular Weight:
285.39
AlogP:
3.78
PSA:
25.61
HBD:
0.0
HBA:
#RotB:
2.0
Source:
PICTILISIB
2
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin; Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung
PI3-kinase class I inhibitor
PICTILISIB
×
Maximum Phase:
2
First Approval:
None
UNII:
ICY00EMP8P
Molecule Type:
Small molecule
Molecular Formula:
C23H27N7O3S2
Molecular Weight:
513.65
AlogP:
2.15
PSA:
107.55
HBD:
1.0
HBA:
#RotB:
5.0
Source:
1
2
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PSA