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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
Small Molecules
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
RETAGLIPTIN
3
Small molecule
Investigational
Unknown
Unknown
Renal Insufficiency; Diabetes Mellitus, Type 2
Unknown
RETAGLIPTIN
×
Maximum Phase:
3
First Approval:
None
UNII:
328C4R3P9L
Molecule Type:
Small molecule
Molecular Formula:
C19H18F6N4O3
Molecular Weight:
464.37
AlogP:
2.41
PSA:
90.45
HBD:
1.0
HBA:
#RotB:
5.0
Source:
RAPASTINEL
3
Protein
Investigational
Unknown
Unknown
Obsessive-Compulsive Disorder; Depressive Disorder, Major
Glutamate [NMDA] receptor partial agonist
RAPASTINEL
×
Maximum Phase:
3
First Approval:
None
UNII:
6A1X56B95E
Molecule Type:
Protein
Molecular Formula:
C18H31N5O6
Molecular Weight:
413.48
AlogP:
-2.97
PSA:
179.29
HBD:
5.0
HBA:
#RotB:
7.0
Source:
DARUSENTAN
3
Small molecule
Investigational
Unknown
Unknown
Hypertension
Endothelin receptor ET-A antagonist
DARUSENTAN
×
Maximum Phase:
3
First Approval:
None
UNII:
33JD57L6RW
Molecule Type:
Small molecule
Molecular Formula:
C22H22N2O6
Molecular Weight:
410.43
AlogP:
2.92
PSA:
100.0
HBD:
1.0
HBA:
#RotB:
9.0
Source:
ALBINTERFERON ALFA-2B
3
Protein
Investigational
Unknown
Unknown
Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic
Interferon alpha/beta receptor agonist
ALBINTERFERON ALFA-2B
×
Maximum Phase:
3
First Approval:
None
UNII:
4DVS4AG4DF
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HYALURONIDASE (OVINE)
3
Enzyme
Investigational
Unknown
Unknown
Unknown
Hyaluronic acid hydrolytic enzyme
HYALURONIDASE (OVINE)
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VERCIRNON SODIUM
3
Small molecule
Investigational
Unknown
Unknown
Crohn Disease
Unknown
VERCIRNON SODIUM
×
Maximum Phase:
3
First Approval:
None
UNII:
9NQF0M8R0M
Molecule Type:
Small molecule
Molecular Formula:
C22H20ClN2NaO4S
Molecular Weight:
466.92
AlogP:
4.3
PSA:
90.18
HBD:
1.0
HBA:
#RotB:
5.0
Source:
ALFERMINOGENE TADENOVEC
3
Gene
Investigational
Unknown
Unknown
Unknown
Unknown
ALFERMINOGENE TADENOVEC
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Gene
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DROPROPIZINE
3
Small molecule
Investigational
Unknown
Unknown
Cough; Inflammation; Rhinitis
Unknown
DROPROPIZINE
×
Maximum Phase:
3
First Approval:
None
UNII:
U0K8WHL37U
Molecule Type:
Small molecule
Molecular Formula:
C13H20N2O2
Molecular Weight:
236.32
AlogP:
0.16
PSA:
46.94
HBD:
2.0
HBA:
#RotB:
4.0
Source:
LAZERTINIB
3
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Unknown
LAZERTINIB
×
Maximum Phase:
3
First Approval:
None
UNII:
4A2Y23XK11
Molecule Type:
Small molecule
Molecular Formula:
C30H34N8O3
Molecular Weight:
554.66
AlogP:
4.1
PSA:
109.67
HBD:
2.0
HBA:
#RotB:
10.0
Source:
ROSIPTOR
3
Small molecule
Investigational
Unknown
Unknown
Dermatitis, Atopic; Pulmonary Disease, Chronic Obstructive; Cystitis, Interstitial
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 activator
ROSIPTOR
×
Maximum Phase:
3
First Approval:
None
UNII:
6R5034F862
Molecule Type:
Small molecule
Molecular Formula:
C20H35NO2
Molecular Weight:
321.5
AlogP:
3.1
PSA:
66.48
HBD:
3.0
HBA:
#RotB:
3.0
Source:
EPROTIROME
3
Small molecule
Investigational
Unknown
Unknown
Hypercholesterolemia; Lipid Metabolism Disorders; Hyperlipoproteinemia Type II
Thyroid hormone receptor beta-1 agonist
EPROTIROME
×
Maximum Phase:
3
First Approval:
None
UNII:
958AQ7B6R1
Molecule Type:
Small molecule
Molecular Formula:
C18H17Br2NO5
Molecular Weight:
487.14
AlogP:
5.25
PSA:
95.86
HBD:
3.0
HBA:
#RotB:
6.0
Source:
KEYHOLE LIMPET HEMOCYANIN
3
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
KEYHOLE LIMPET HEMOCYANIN
×
Maximum Phase:
3
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MITOMYCIN A
3
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular
Unknown
MITOMYCIN A
×
Maximum Phase:
3
First Approval:
None
UNII:
87TMG6FJHV
Molecule Type:
Small molecule
Molecular Formula:
C16H19N3O6
Molecular Weight:
349.34
AlogP:
-0.96
PSA:
130.1
HBD:
2.0
HBA:
#RotB:
4.0
Source:
ST. JOHN'S WORT
3
Unknown
Investigational
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity; Irritable Bowel Syndrome; Tobacco Use Disorder; Breast Neoplasms; Depressive Disorder; Genital Neoplasms, Male; Head and Neck Neoplasms; Kidney Neoplasms; Pain; Raynaud Disease
Unknown
ST. JOHN'S WORT
×
Maximum Phase:
3
First Approval:
None
UNII:
UFH8805FKA
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PENPULIMAB
3
Antibody
Investigational
Unknown
Unknown
Hodgkin Disease; Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Lung Neoplasms; Nasopharyngeal Neoplasms
Programmed cell death protein 1 inhibitor
PENPULIMAB
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INDIGO
3
Small molecule
Investigational
Unknown
Unknown
Anus Neoplasms; Dermatitis, Atopic; Psoriasis; Leukemia, Promyelocytic, Acute
Unknown
INDIGO
×
Maximum Phase:
3
First Approval:
None
UNII:
1G5BK41P4F
Molecule Type:
Small molecule
Molecular Formula:
C16H10N2O2
Molecular Weight:
262.27
AlogP:
2.81
PSA:
58.2
HBD:
2.0
HBA:
#RotB:
0.0
Source:
PEGAPTANIB OCTASODIUM
3
Unknown
Investigational
Unknown
Unknown
Retinal Neovascularization; Wet Macular Degeneration
Vascular endothelial growth factor A inhibitor
PEGAPTANIB OCTASODIUM
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INGENOL
3
Small molecule
Investigational
Unknown
Unknown
Keratosis, Actinic
Unknown
INGENOL
×
Maximum Phase:
3
First Approval:
None
UNII:
IC77UZI9G8
Molecule Type:
Small molecule
Molecular Formula:
C20H28O5
Molecular Weight:
348.44
AlogP:
0.82
PSA:
97.99
HBD:
4.0
HBA:
#RotB:
1.0
Source:
KARENITECIN
3
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Brain Neoplasms; Lung Neoplasms; Melanoma; Ovarian Neoplasms
Unknown
KARENITECIN
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C25H28N2O4Si
Molecular Weight:
448.6
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
KISSPEPTIN-10
3
Protein
Investigational
Unknown
Unknown
Pregnancy; Hypogonadism; Infertility
Unknown
KISSPEPTIN-10
×
Maximum Phase:
3
First Approval:
None
UNII:
FS1N52VS3S
Molecule Type:
Protein
Molecular Formula:
C63H83N17O14
Molecular Weight:
1302.46
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
RANIMUSTINE
3
Small molecule
Investigational
Unknown
Unknown
Leukemia-Lymphoma, Adult T-Cell; Neoplasms
Unknown
RANIMUSTINE
×
Maximum Phase:
3
First Approval:
None
UNII:
RYH2T97J77
Molecule Type:
Small molecule
Molecular Formula:
C10H18ClN3O7
Molecular Weight:
327.72
AlogP:
-1.63
PSA:
140.92
HBD:
4.0
HBA:
#RotB:
6.0
Source:
BOCOCIZUMAB
3
Antibody
Investigational
Unknown
Unknown
Hypercholesterolemia; Cardiovascular Diseases; Hyperlipidemias; Hyperlipoproteinemia Type II
Subtilisin/kexin type 9 inhibitor
BOCOCIZUMAB
×
Maximum Phase:
3
First Approval:
None
UNII:
45M75JVK38
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HETROMBOPAG OLAMINE
3
Unknown
Investigational
Unknown
Unknown
Anemia, Aplastic; Purpura, Thrombocytopenic, Idiopathic
Unknown
HETROMBOPAG OLAMINE
×
Maximum Phase:
3
First Approval:
None
UNII:
V45T2I862X
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AMBROXOL
3
Small molecule
Investigational
Unknown
Unknown
Cough; Dementia; Gaucher Disease; Parkinson Disease; Pharyngitis; Respiratory Tract Diseases
Unknown
AMBROXOL
×
Maximum Phase:
3
First Approval:
None
UNII:
200168S0CL
Molecule Type:
Small molecule
Molecular Formula:
C13H18Br2N2O
Molecular Weight:
378.11
AlogP:
3.19
PSA:
58.28
HBD:
3.0
HBA:
#RotB:
3.0
Source:
MELARSOPROL
3
Small molecule
Investigational
Unknown
Unknown
Leishmaniasis; Trypanosomiasis
Unknown
MELARSOPROL
×
Maximum Phase:
3
First Approval:
None
UNII:
ZF3786Q2E8
Molecule Type:
Small molecule
Molecular Formula:
C12H15AsN6OS2
Molecular Weight:
398.35
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
ALBUVIRTIDE
3
Protein
Investigational
Unknown
Unknown
HIV Infections; Acquired Immunodeficiency Syndrome
Unknown
ALBUVIRTIDE
×
Maximum Phase:
3
First Approval:
None
UNII:
MG9PC54E43
Molecule Type:
Protein
Molecular Formula:
C204H306N54O72
Molecular Weight:
4667.0
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
SMALLPOX VACCINE
3
Unknown
Investigational
Unknown
Unknown
Fever; HIV Infections; Smallpox
Unknown
SMALLPOX VACCINE
×
Maximum Phase:
3
First Approval:
None
UNII:
4SV59689SK
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
UMIFENOVIR
3
Small molecule
Investigational
Unknown
Unknown
Influenza, Human; Virus Diseases
Hemagglutinin negative modulator
UMIFENOVIR
×
Maximum Phase:
3
First Approval:
None
UNII:
93M09WW4RU
Molecule Type:
Small molecule
Molecular Formula:
C22H25BrN2O3S
Molecular Weight:
477.42
AlogP:
5.18
PSA:
54.7
HBD:
1.0
HBA:
#RotB:
7.0
Source:
GARLIC
3
Unknown
Investigational
Unknown
Unknown
Hypercholesterolemia; Lymphoma, Follicular; Stomatitis, Denture; Alopecia Areata
Unknown
GARLIC
×
Maximum Phase:
3
First Approval:
None
UNII:
V1V998DC17
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LORMETAZEPAM
3
Small molecule
Investigational
Unknown
Unknown
Anxiety; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders
Unknown
LORMETAZEPAM
×
Maximum Phase:
3
First Approval:
None
UNII:
GU56C842ZA
Molecule Type:
Small molecule
Molecular Formula:
C16H12Cl2N2O2
Molecular Weight:
335.19
AlogP:
3.13
PSA:
52.9
HBD:
1.0
HBA:
#RotB:
1.0
Source:
NABIXIMOLS
3
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Squamous Cell; Liver Diseases; Neoplasms; Autistic Disorder; Marijuana Abuse; Peripheral Nervous System Diseases; Stress Disorders, Post-Traumatic; Cerebral Palsy; Fever; Multiple Sclerosis; Neuralgia; Pain; Tourette Syndrome
Unknown
NABIXIMOLS
×
Maximum Phase:
3
First Approval:
None
UNII:
K4H93P747O
Molecule Type:
Small molecule
Molecular Formula:
C42H60O4
Molecular Weight:
628.94
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
HUNTERASE
3
Enzyme
Investigational
Unknown
Unknown
Unknown
Unknown
HUNTERASE
×
Maximum Phase:
3
First Approval:
None
UNII:
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SHR-1210
3
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
SHR-1210
×
Maximum Phase:
3
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GV-971
3
Unknown
Investigational
Unknown
Unknown
Alzheimer Disease
Unknown
GV-971
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ANAPRAZOLE
3
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ANAPRAZOLE
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C21H24N2O4S
Molecular Weight:
400.5
AlogP:
3.53
PSA:
73.44
HBD:
1.0
HBA:
#RotB:
8.0
Source:
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Molecular Formula
Molecular Weight
ALogP
PSA