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Therapeutic Area
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
TUROFEXORATE ISOPROPYL
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Bile acid receptor FXR agonist
TUROFEXORATE ISOPROPYL
×
Maximum Phase:
1
First Approval:
None
UNII:
S6KDM312I5
Molecule Type:
Small molecule
Molecular Formula:
C25H24F2N2O3
Molecular Weight:
438.47
AlogP:
5.17
PSA:
62.4
HBD:
1.0
HBA:
#RotB:
3.0
Source:
IM-156 FREE BASE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
IM-156 FREE BASE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C13H16F3N5O
Molecular Weight:
315.3
AlogP:
2.55
PSA:
84.23
HBD:
4.0
HBA:
#RotB:
2.0
Source:
MCAF5352A
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
MCAF5352A
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ZIRCONIUM ZR-89-DESFERRIOXAMINE-IAB22M2C
1
Unknown
Investigational
Unknown
Unknown
Glioblastoma; Lymphoma, Non-Hodgkin
Unknown
ZIRCONIUM ZR-89-DESFERRIOXAMINE-IAB22M2C
×
Maximum Phase:
1
First Approval:
None
UNII:
J6AJI0OZ1O
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
REBAUDIOSIDE A
1
Oligosaccharide
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
REBAUDIOSIDE A
×
Maximum Phase:
1
First Approval:
None
UNII:
B3FUD0528F
Molecule Type:
Oligosaccharide
Molecular Formula:
C44H70O23
Molecular Weight:
967.02
AlogP:
-5.11
PSA:
374.13
HBD:
14.0
HBA:
#RotB:
12.0
Source:
BIO89-100
1
Unknown
Investigational
Unknown
Unknown
Hypertriglyceridemia; Non-alcoholic Fatty Liver Disease
Unknown
BIO89-100
×
Maximum Phase:
1
First Approval:
None
UNII:
UO870O6MFS
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ONAPRISTONE
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Neoplasms; Prostatic Neoplasms
Progesterone receptor antagonist
ONAPRISTONE
×
Maximum Phase:
1
First Approval:
None
UNII:
H6H7G23O3N
Molecule Type:
Small molecule
Molecular Formula:
C29H39NO3
Molecular Weight:
449.64
AlogP:
5.16
PSA:
60.77
HBD:
2.0
HBA:
#RotB:
5.0
Source:
BEMOTRIZINOL
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BEMOTRIZINOL
×
Maximum Phase:
1
First Approval:
None
UNII:
PWZ1720CBH
Molecule Type:
Small molecule
Molecular Formula:
C38H49N3O5
Molecular Weight:
627.83
AlogP:
9.48
PSA:
106.82
HBD:
2.0
HBA:
#RotB:
18.0
Source:
BALAFILCON A
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BALAFILCON A
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
UNESBULIN
1
Small molecule
Investigational
Unknown
Unknown
Diffuse Intrinsic Pontine Glioma; Leiomyosarcoma; Neoplasms; Ovarian Neoplasms
Unknown
UNESBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
Z4HZ70S62Q
Molecule Type:
Small molecule
Molecular Formula:
C19H13F5N6
Molecular Weight:
420.35
AlogP:
4.75
PSA:
81.65
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PEGTIBATINASE
1
Enzyme
Investigational
Unknown
Unknown
Homocystinuria
Unknown
PEGTIBATINASE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BGT226
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BGT226
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SELITRECTINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Neurotrophic tyrosine kinase receptor inhibitor
SELITRECTINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
0J45910S3X
Molecule Type:
Small molecule
Molecular Formula:
C20H21FN6O
Molecular Weight:
380.43
AlogP:
2.67
PSA:
75.42
HBD:
1.0
HBA:
#RotB:
0.0
Source:
LEVONORGESTREL BUTANOATE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LEVONORGESTREL BUTANOATE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAVOLIMAB
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Unknown
TAVOLIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
4LU9B48U4D
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HYDROXYNORKETAMINE, (2R,6R)
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HYDROXYNORKETAMINE, (2R,6R)
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C12H14ClNO2
Molecular Weight:
239.7
AlogP:
1.61
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
1.0
Source:
NT-219
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NT-219
×
Maximum Phase:
1
First Approval:
None
UNII:
K1WT1A1UP5
Molecule Type:
Small molecule
Molecular Formula:
C16H14BrNO5S
Molecular Weight:
412.26
AlogP:
3.11
PSA:
113.18
HBD:
6.0
HBA:
#RotB:
4.0
Source:
FGF-1 141
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
FGF-1 141
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ORILANOLIMAB
1
Antibody
Investigational
Unknown
Unknown
Anemia, Hemolytic, Autoimmune
Unknown
ORILANOLIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
1LTT6HMX9N
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BTA-9881
1
Small molecule
Investigational
Unknown
Unknown
Respiratory Syncytial Virus Infections
Unknown
BTA-9881
×
Maximum Phase:
1
First Approval:
None
UNII:
9VR1J6U4XG
Molecule Type:
Small molecule
Molecular Formula:
C21H15ClN4O2
Molecular Weight:
390.83
AlogP:
2.94
PSA:
66.4
HBD:
0.0
HBA:
#RotB:
2.0
Source:
FENAMIC ACID
1
Small molecule
Investigational
Unknown
Unknown
Pancreatic Neoplasms
Unknown
FENAMIC ACID
×
Maximum Phase:
1
First Approval:
None
UNII:
952VN06WBB
Molecule Type:
Small molecule
Molecular Formula:
C13H11NO2
Molecular Weight:
213.24
AlogP:
3.13
PSA:
49.33
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PAC-1
1
Small molecule
Investigational
Unknown
Unknown
Astrocytoma; Glioblastoma; Neuroendocrine Tumors
Unknown
PAC-1
×
Maximum Phase:
1
First Approval:
None
UNII:
9LIS8N0B2C
Molecule Type:
Small molecule
Molecular Formula:
C23H28N4O2
Molecular Weight:
392.5
AlogP:
2.39
PSA:
68.17
HBD:
2.0
HBA:
#RotB:
8.0
Source:
SALCAPROZATE SODIUM
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus; Diabetes Mellitus, Type 2
Unknown
SALCAPROZATE SODIUM
×
Maximum Phase:
1
First Approval:
None
UNII:
1YTW0422YU
Molecule Type:
Small molecule
Molecular Formula:
C15H20NNaO4
Molecular Weight:
301.32
AlogP:
2.55
PSA:
86.63
HBD:
3.0
HBA:
#RotB:
9.0
Source:
TAK-733
1
Small molecule
Investigational
Unknown
Unknown
Melanoma; Neoplasms
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
TAK-733
×
Maximum Phase:
1
First Approval:
None
UNII:
5J61HSP0QJ
Molecule Type:
Small molecule
Molecular Formula:
C17H15F2IN4O4
Molecular Weight:
504.23
AlogP:
1.07
PSA:
109.38
HBD:
3.0
HBA:
#RotB:
5.0
Source:
MEDI-547
1
Unknown
Investigational
Unknown
Unknown
Neoplasms
Unknown
MEDI-547
×
Maximum Phase:
1
First Approval:
None
UNII:
D21E6RU881
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MOSUNETUZUMAB
1
Antibody
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular
B-lymphocyte antigen CD20 binding agent
MOSUNETUZUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
LDJ89SS0YG
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BAY-1217389
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Dual specificity protein kinase TTK inhibitor
BAY-1217389
×
Maximum Phase:
1
First Approval:
None
UNII:
M964LB1114
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
QC-12
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
QC-12
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IMC-EB10
1
Antibody
Investigational
Unknown
Unknown
Leukemia, Myeloid
Tyrosine-protein kinase receptor FLT3 inhibitor
IMC-EB10
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ALTIRATINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Hepatocyte growth factor receptor inhibitor
ALTIRATINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
T678746713
Molecule Type:
Small molecule
Molecular Formula:
C26H21F3N4O4
Molecular Weight:
510.47
AlogP:
5.0
PSA:
109.42
HBD:
3.0
HBA:
#RotB:
8.0
Source:
SAD448
1
Small molecule
Investigational
Unknown
Unknown
Ocular Hypertension
Cannabinoid CB1 receptor agonist
SAD448
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DS-1062A
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
DS-1062A
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-1390
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Unknown
AZD-1390
×
Maximum Phase:
1
First Approval:
None
UNII:
CI43QFE22O
Molecule Type:
Small molecule
Molecular Formula:
C27H32FN5O2
Molecular Weight:
477.58
AlogP:
4.93
PSA:
65.18
HBD:
0.0
HBA:
#RotB:
7.0
Source:
E7107
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
E7107
×
Maximum Phase:
1
First Approval:
None
UNII:
R60DZX1E2N
Molecule Type:
Small molecule
Molecular Formula:
C40H66N2O9
Molecular Weight:
718.97
AlogP:
5.05
PSA:
152.53
HBD:
4.0
HBA:
#RotB:
10.0
Source:
TELINAVIR
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections
HIV-1 protease inhibitor
TELINAVIR
×
Maximum Phase:
1
First Approval:
None
UNII:
IZF55EH3CG
Molecule Type:
Small molecule
Molecular Formula:
C33H44N6O5
Molecular Weight:
604.75
AlogP:
2.76
PSA:
166.75
HBD:
5.0
HBA:
#RotB:
13.0
Source:
1
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86
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Molecular Formula
Molecular Weight
ALogP
PSA