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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
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Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
MDX-1342
1
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Leukemia, Lymphocytic, Chronic, B-Cell
B-lymphocyte antigen CD19 binding agent
MDX-1342
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
REBAUDIOSIDE A
1
Oligosaccharide
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
REBAUDIOSIDE A
×
Maximum Phase:
1
First Approval:
None
UNII:
B3FUD0528F
Molecule Type:
Oligosaccharide
Molecular Formula:
C44H70O23
Molecular Weight:
967.02
AlogP:
-5.11
PSA:
374.13
HBD:
14.0
HBA:
#RotB:
12.0
Source:
LODAPOLIMAB
1
Antibody
Investigational
Unknown
Unknown
Breast Neoplasms; Melanoma; Neoplasms; Pancreatic Neoplasms
Unknown
LODAPOLIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
NR4MAD6PPB
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MDM2
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
MDM2
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TUROFEXORATE ISOPROPYL
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Bile acid receptor FXR agonist
TUROFEXORATE ISOPROPYL
×
Maximum Phase:
1
First Approval:
None
UNII:
S6KDM312I5
Molecule Type:
Small molecule
Molecular Formula:
C25H24F2N2O3
Molecular Weight:
438.47
AlogP:
5.17
PSA:
62.4
HBD:
1.0
HBA:
#RotB:
3.0
Source:
MCAF5352A
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
MCAF5352A
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FARLETUZUMAB ECTERIBULIN
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Unknown
FARLETUZUMAB ECTERIBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RG-7795
1
Unknown
Investigational
Unknown
Unknown
Hepatitis C
Unknown
RG-7795
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LBY-135
1
Antibody
Investigational
Unknown
Unknown
Unknown
Tumor necrosis factor receptor superfamily member 10B agonist
LBY-135
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NANATINOSTAT
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
NANATINOSTAT
×
Maximum Phase:
1
First Approval:
None
UNII:
YTL7A418KQ
Molecule Type:
Small molecule
Molecular Formula:
C20H19FN6O2
Molecular Weight:
394.41
AlogP:
1.51
PSA:
103.27
HBD:
3.0
HBA:
#RotB:
5.0
Source:
TERGENPUMATUCEL-L
1
Cell
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Unknown
TERGENPUMATUCEL-L
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Cell
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAK-915
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
TAK-915
×
Maximum Phase:
1
First Approval:
None
UNII:
0M4DME62Y9
Molecule Type:
Small molecule
Molecular Formula:
C19H18F4N4O5
Molecular Weight:
458.37
AlogP:
2.98
PSA:
102.02
HBD:
2.0
HBA:
#RotB:
6.0
Source:
LONTUCIREV (REPLICATING ADENOVIRUS)
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LONTUCIREV (REPLICATING ADENOVIRUS)
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ONGERICIMAB
1
Antibody
Investigational
Unknown
Unknown
Hypercholesterolemia; Hyperlipidemias
Unknown
ONGERICIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
X126G5DZ36
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RECOMBINANT METHIONYL HUMAN BRAIN-DERIVED NEUROTROPHIC FACTOR
1
Unknown
Investigational
Unknown
Unknown
Hearing Loss, Sensorineural
Unknown
RECOMBINANT METHIONYL HUMAN BRAIN-DERIVED NEUROTROPHIC FACTOR
×
Maximum Phase:
1
First Approval:
None
UNII:
7171WSG8A2
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CEDELIZUMAB
1
Antibody
Investigational
Unknown
Unknown
Unknown
T-cell surface antigen CD4 inhibitor
CEDELIZUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NT-219
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NT-219
×
Maximum Phase:
1
First Approval:
None
UNII:
K1WT1A1UP5
Molecule Type:
Small molecule
Molecular Formula:
C16H14BrNO5S
Molecular Weight:
412.26
AlogP:
3.11
PSA:
113.18
HBD:
6.0
HBA:
#RotB:
4.0
Source:
GDC-0349
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GDC-0349
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BALAFILCON A
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BALAFILCON A
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CABIOTRAXETAN LUTETIUM LU-177
1
Unknown
Investigational
Unknown
Unknown
Lymphoma
Unknown
CABIOTRAXETAN LUTETIUM LU-177
×
Maximum Phase:
1
First Approval:
None
UNII:
5U8L0A8I80
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ABT-806I
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
ABT-806I
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
UNESBULIN
1
Small molecule
Investigational
Unknown
Unknown
Diffuse Intrinsic Pontine Glioma; Leiomyosarcoma; Neoplasms; Ovarian Neoplasms
Unknown
UNESBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
Z4HZ70S62Q
Molecule Type:
Small molecule
Molecular Formula:
C19H13F5N6
Molecular Weight:
420.35
AlogP:
4.75
PSA:
81.65
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PERAKIZUMAB
1
Antibody
Investigational
Unknown
Unknown
Arthritis, Psoriatic
Interleukin 17A inhibitor
PERAKIZUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
867X5909JO
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IRX4310
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Retinoic acid receptor antagonist
IRX4310
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
THELIATINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
THELIATINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
6ZZ3B7NZ0B
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HYDROXYNORKETAMINE, (2R,6R)
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HYDROXYNORKETAMINE, (2R,6R)
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C12H14ClNO2
Molecular Weight:
239.7
AlogP:
1.61
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
1.0
Source:
CAB
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
CAB
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CH5132799
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CH5132799
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PEGTIBATINASE
1
Enzyme
Investigational
Unknown
Unknown
Homocystinuria
Unknown
PEGTIBATINASE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MK-8245
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
MK-8245
×
Maximum Phase:
1
First Approval:
None
UNII:
537E7QE8LX
Molecule Type:
Small molecule
Molecular Formula:
C17H16BrFN6O4
Molecular Weight:
467.26
AlogP:
2.36
PSA:
119.4
HBD:
1.0
HBA:
#RotB:
6.0
Source:
CX-157
1
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major
Unknown
CX-157
×
Maximum Phase:
1
First Approval:
None
UNII:
O6L62LZJ0Q
Molecule Type:
Small molecule
Molecular Formula:
C14H8F4O4S
Molecular Weight:
348.27
AlogP:
3.71
PSA:
52.6
HBD:
0.0
HBA:
#RotB:
2.0
Source:
ULOCUPLUMAB
1
Antibody
Investigational
Unknown
Unknown
Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Follicular; Multiple Myeloma; Neoplasms; Waldenstrom Macroglobulinemia
C-X-C chemokine receptor type 4 inhibitor
ULOCUPLUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
7KNP87L4X4
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SELITRECTINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Neurotrophic tyrosine kinase receptor inhibitor
SELITRECTINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
0J45910S3X
Molecule Type:
Small molecule
Molecular Formula:
C20H21FN6O
Molecular Weight:
380.43
AlogP:
2.67
PSA:
75.42
HBD:
1.0
HBA:
#RotB:
0.0
Source:
BIO89-100
1
Unknown
Investigational
Unknown
Unknown
Hypertriglyceridemia; Non-alcoholic Fatty Liver Disease
Unknown
BIO89-100
×
Maximum Phase:
1
First Approval:
None
UNII:
UO870O6MFS
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ELTANEXOR
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ELTANEXOR
×
Maximum Phase:
1
First Approval:
None
UNII:
Q59IQJ9NTK
Molecule Type:
Small molecule
Molecular Formula:
C17H10F6N6O
Molecular Weight:
428.3
AlogP:
3.26
PSA:
99.58
HBD:
1.0
HBA:
#RotB:
4.0
Source:
1
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Molecular Formula
Molecular Weight
ALogP
PSA