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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
THELIATINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
THELIATINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
6ZZ3B7NZ0B
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CG-200745
1
Small molecule
Investigational
Unknown
Unknown
Myelodysplastic Syndromes; Neoplasms; Pancreatic Neoplasms
Unknown
CG-200745
×
Maximum Phase:
1
First Approval:
None
UNII:
4I8MLM7L2H
Molecule Type:
Small molecule
Molecular Formula:
C24H33N3O4
Molecular Weight:
427.55
AlogP:
3.28
PSA:
90.9
HBD:
3.0
HBA:
#RotB:
13.0
Source:
SRX251
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Vasopressin V1a receptor antagonist
SRX251
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MCAF5352A
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
MCAF5352A
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
REBAUDIOSIDE A
1
Oligosaccharide
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
REBAUDIOSIDE A
×
Maximum Phase:
1
First Approval:
None
UNII:
B3FUD0528F
Molecule Type:
Oligosaccharide
Molecular Formula:
C44H70O23
Molecular Weight:
967.02
AlogP:
-5.11
PSA:
374.13
HBD:
14.0
HBA:
#RotB:
12.0
Source:
ATU027
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
ATU027
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MK-8245
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
MK-8245
×
Maximum Phase:
1
First Approval:
None
UNII:
537E7QE8LX
Molecule Type:
Small molecule
Molecular Formula:
C17H16BrFN6O4
Molecular Weight:
467.26
AlogP:
2.36
PSA:
119.4
HBD:
1.0
HBA:
#RotB:
6.0
Source:
GSK-1995057
1
Antibody
Investigational
Unknown
Unknown
Respiratory Tract Diseases
Tumor necrosis factor receptor R1 inhibitor
GSK-1995057
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ATB-346
1
Small molecule
Investigational
Unknown
Unknown
Chronic Pain; Stomach Ulcer; Osteoarthritis
Unknown
ATB-346
×
Maximum Phase:
1
First Approval:
None
UNII:
3096O7WP53
Molecule Type:
Small molecule
Molecular Formula:
C21H19NO3S
Molecular Weight:
365.45
AlogP:
4.19
PSA:
61.55
HBD:
1.0
HBA:
#RotB:
5.0
Source:
NT-219
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NT-219
×
Maximum Phase:
1
First Approval:
None
UNII:
K1WT1A1UP5
Molecule Type:
Small molecule
Molecular Formula:
C16H14BrNO5S
Molecular Weight:
412.26
AlogP:
3.11
PSA:
113.18
HBD:
6.0
HBA:
#RotB:
4.0
Source:
CX-157
1
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major
Unknown
CX-157
×
Maximum Phase:
1
First Approval:
None
UNII:
O6L62LZJ0Q
Molecule Type:
Small molecule
Molecular Formula:
C14H8F4O4S
Molecular Weight:
348.27
AlogP:
3.71
PSA:
52.6
HBD:
0.0
HBA:
#RotB:
2.0
Source:
ULOCUPLUMAB
1
Antibody
Investigational
Unknown
Unknown
Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Follicular; Multiple Myeloma; Neoplasms; Waldenstrom Macroglobulinemia
C-X-C chemokine receptor type 4 inhibitor
ULOCUPLUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
7KNP87L4X4
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SAR-439459
1
Unknown
Investigational
Unknown
Unknown
Liver Neoplasms; Multiple Myeloma; Neoplasms
Unknown
SAR-439459
×
Maximum Phase:
1
First Approval:
None
UNII:
7EFI23P78R
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TUROFEXORATE ISOPROPYL
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Bile acid receptor FXR agonist
TUROFEXORATE ISOPROPYL
×
Maximum Phase:
1
First Approval:
None
UNII:
S6KDM312I5
Molecule Type:
Small molecule
Molecular Formula:
C25H24F2N2O3
Molecular Weight:
438.47
AlogP:
5.17
PSA:
62.4
HBD:
1.0
HBA:
#RotB:
3.0
Source:
GSK-1614235
1
Unknown
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
GSK-1614235
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ATIPAMEZOLE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ATIPAMEZOLE
×
Maximum Phase:
1
First Approval:
None
UNII:
03N9U5JAF6
Molecule Type:
Small molecule
Molecular Formula:
C14H16N2
Molecular Weight:
212.3
AlogP:
2.86
PSA:
28.68
HBD:
1.0
HBA:
#RotB:
2.0
Source:
BALAFILCON A
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BALAFILCON A
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NORBUPRENORPHINE
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
NORBUPRENORPHINE
×
Maximum Phase:
1
First Approval:
None
UNII:
7E53B4O073
Molecule Type:
Small molecule
Molecular Formula:
C25H35NO4
Molecular Weight:
413.56
AlogP:
3.29
PSA:
70.95
HBD:
3.0
HBA:
#RotB:
2.0
Source:
BENDAMUSTINE DODECYL ESTER
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
BENDAMUSTINE DODECYL ESTER
×
Maximum Phase:
1
First Approval:
None
UNII:
22C7JIO84O
Molecule Type:
Small molecule
Molecular Formula:
C28H45Cl2N3O2
Molecular Weight:
526.59
AlogP:
7.64
PSA:
47.36
HBD:
0.0
HBA:
#RotB:
20.0
Source:
UNESBULIN
1
Small molecule
Investigational
Unknown
Unknown
Diffuse Intrinsic Pontine Glioma; Leiomyosarcoma; Neoplasms; Ovarian Neoplasms
Unknown
UNESBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
Z4HZ70S62Q
Molecule Type:
Small molecule
Molecular Formula:
C19H13F5N6
Molecular Weight:
420.35
AlogP:
4.75
PSA:
81.65
HBD:
2.0
HBA:
#RotB:
3.0
Source:
SELITRECTINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Neurotrophic tyrosine kinase receptor inhibitor
SELITRECTINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
0J45910S3X
Molecule Type:
Small molecule
Molecular Formula:
C20H21FN6O
Molecular Weight:
380.43
AlogP:
2.67
PSA:
75.42
HBD:
1.0
HBA:
#RotB:
0.0
Source:
BISTHIANOSTAT
1
Small molecule
Investigational
Unknown
Unknown
Multiple Myeloma
Unknown
BISTHIANOSTAT
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C15H18N4O3S2
Molecular Weight:
366.47
AlogP:
2.55
PSA:
104.21
HBD:
3.0
HBA:
#RotB:
8.0
Source:
TERPINEN-4-OL
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
TERPINEN-4-OL
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HYDROXYNORKETAMINE, (2R,6R)
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HYDROXYNORKETAMINE, (2R,6R)
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C12H14ClNO2
Molecular Weight:
239.7
AlogP:
1.61
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
1.0
Source:
PF-06840003
1
Small molecule
Investigational
Unknown
Unknown
Astrocytoma; Oligodendroglioma
Unknown
PF-06840003
×
Maximum Phase:
1
First Approval:
None
UNII:
5K1FUI0T2C
Molecule Type:
Small molecule
Molecular Formula:
C12H9FN2O2
Molecular Weight:
232.21
AlogP:
1.44
PSA:
61.96
HBD:
2.0
HBA:
#RotB:
1.0
Source:
IMA-026
1
Unknown
Investigational
Unknown
Unknown
Asthma
Unknown
IMA-026
×
Maximum Phase:
1
First Approval:
None
UNII:
P52JII7PAL
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TNB-486
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
TNB-486
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RG-7256
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Serine/threonine-protein kinase B-raf inhibitor
RG-7256
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DIRLOTAPIDE
1
Small molecule
Investigational
Unknown
Unknown
Obesity
Unknown
DIRLOTAPIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
578H0RMP25
Molecule Type:
Small molecule
Molecular Formula:
C40H33F3N4O3
Molecular Weight:
674.72
AlogP:
8.25
PSA:
83.44
HBD:
2.0
HBA:
#RotB:
9.0
Source:
PEGTIBATINASE
1
Enzyme
Investigational
Unknown
Unknown
Homocystinuria
Unknown
PEGTIBATINASE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BIO89-100
1
Unknown
Investigational
Unknown
Unknown
Hypertriglyceridemia; Non-alcoholic Fatty Liver Disease
Unknown
BIO89-100
×
Maximum Phase:
1
First Approval:
None
UNII:
UO870O6MFS
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RX-0201
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
RX-0201
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
E7107
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
E7107
×
Maximum Phase:
1
First Approval:
None
UNII:
R60DZX1E2N
Molecule Type:
Small molecule
Molecular Formula:
C40H66N2O9
Molecular Weight:
718.97
AlogP:
5.05
PSA:
152.53
HBD:
4.0
HBA:
#RotB:
10.0
Source:
TIBULIZUMAB
1
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Sjogren's Syndrome
Interleukin 17A inhibitor
TIBULIZUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
42HQ15W1ZF
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DELANZOMIB
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin; Multiple Myeloma
Unknown
DELANZOMIB
×
Maximum Phase:
1
First Approval:
None
UNII:
6IF28942WO
Molecule Type:
Small molecule
Molecular Formula:
C21H28BN3O5
Molecular Weight:
413.28
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
1
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Molecular Formula
Molecular Weight
ALogP
PSA