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ENT (5)
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NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
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PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
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Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
LEXIBULIN
2
Small molecule
Investigational
Unknown
Unknown
Glioblastoma; Multiple Myeloma
Tubulin inhibitor
LEXIBULIN
×
Maximum Phase:
2
First Approval:
None
UNII:
2GTU230HA1
Molecule Type:
Small molecule
Molecular Formula:
C24H30N6O2
Molecular Weight:
434.54
AlogP:
4.95
PSA:
101.06
HBD:
3.0
HBA:
#RotB:
9.0
Source:
DUVOGLUSTAT
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
DUVOGLUSTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
FZ56898FLE
Molecule Type:
Small molecule
Molecular Formula:
C6H13NO4
Molecular Weight:
163.17
AlogP:
-2.97
PSA:
92.95
HBD:
5.0
HBA:
#RotB:
1.0
Source:
SIMPINICLINE
2
Small molecule
Investigational
Unknown
Unknown
Gastroparesis; Dry Eye Syndromes; Irritable Bowel Syndrome
Neuronal acetylcholine receptor; alpha3/beta4 agonist
SIMPINICLINE
×
Maximum Phase:
2
First Approval:
None
UNII:
09936A4QSN
Molecule Type:
Small molecule
Molecular Formula:
C10H13N3
Molecular Weight:
175.23
AlogP:
1.1
PSA:
37.81
HBD:
1.0
HBA:
#RotB:
2.0
Source:
CALDARET
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CALDARET
×
Maximum Phase:
2
First Approval:
None
UNII:
9L3Y3IJ2HI
Molecule Type:
Small molecule
Molecular Formula:
C11H16N2O3S
Molecular Weight:
256.33
AlogP:
0.65
PSA:
69.64
HBD:
2.0
HBA:
#RotB:
2.0
Source:
BIRICODAR
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BIRICODAR
×
Maximum Phase:
2
First Approval:
None
UNII:
3KG76X4KJK
Molecule Type:
Small molecule
Molecular Formula:
C34H41N3O7
Molecular Weight:
603.72
AlogP:
5.02
PSA:
117.15
HBD:
0.0
HBA:
#RotB:
15.0
Source:
DERAZANTINIB
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Cholangiocarcinoma
Fibroblast growth factor receptor inhibitor
DERAZANTINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
N9B0H171MJ
Molecule Type:
Small molecule
Molecular Formula:
C29H29FN4O
Molecular Weight:
468.58
AlogP:
5.49
PSA:
59.07
HBD:
2.0
HBA:
#RotB:
9.0
Source:
TAK-653
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder
Glutamate receptor ionotropic AMPA positive allosteric modulator
TAK-653
×
Maximum Phase:
2
First Approval:
None
UNII:
9E3TOE5RIZ
Molecule Type:
Small molecule
Molecular Formula:
C19H23N3O3S
Molecular Weight:
373.48
AlogP:
3.11
PSA:
71.33
HBD:
0.0
HBA:
#RotB:
3.0
Source:
SELICICLIB
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Neoplasms; Carcinoma, Non-Small-Cell Lung; Cystic Fibrosis; Pituitary ACTH Hypersecretion
Cyclin-dependent kinase 1 inhibitor
SELICICLIB
×
Maximum Phase:
2
First Approval:
None
UNII:
0ES1C2KQ94
Molecule Type:
Small molecule
Molecular Formula:
C19H26N6O
Molecular Weight:
354.46
AlogP:
3.2
PSA:
87.89
HBD:
3.0
HBA:
#RotB:
8.0
Source:
TECALCET HYDROCHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Calcium sensing receptor modulator
TECALCET HYDROCHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
3HP28R98LC
Molecule Type:
Small molecule
Molecular Formula:
C18H23Cl2NO
Molecular Weight:
340.29
AlogP:
4.63
PSA:
21.26
HBD:
1.0
HBA:
#RotB:
7.0
Source:
ISLATRAVIR
2
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
ISLATRAVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
QPQ082R25D
Molecule Type:
Small molecule
Molecular Formula:
C12H12FN5O3
Molecular Weight:
293.26
AlogP:
-0.81
PSA:
119.31
HBD:
3.0
HBA:
#RotB:
2.0
Source:
CX 4945
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CX 4945
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PAQUINIMOD
2
Small molecule
Investigational
Unknown
Unknown
Lupus Erythematosus, Systemic; Scleroderma, Systemic
Unknown
PAQUINIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
HB76GLG27V
Molecule Type:
Small molecule
Molecular Formula:
C21H22N2O3
Molecular Weight:
350.42
AlogP:
3.47
PSA:
62.54
HBD:
1.0
HBA:
#RotB:
4.0
Source:
CARBON MONOXIDE
2
Small molecule
Investigational
Unknown
Unknown
Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Ileus; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome
Unknown
CARBON MONOXIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
7U1EE4V452
Molecule Type:
Small molecule
Molecular Formula:
CO
Molecular Weight:
28.01
AlogP:
-0.04
PSA:
19.9
HBD:
0.0
HBA:
#RotB:
0.0
Source:
AL-12182
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Prostanoid FP receptor agonist
AL-12182
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C25H35ClO6
Molecular Weight:
467.0
AlogP:
4.47
PSA:
85.22
HBD:
2.0
HBA:
#RotB:
13.0
Source:
CANNABIDIVARIN
2
Small molecule
Investigational
Unknown
Unknown
Epilepsy; Child Development Disorders, Pervasive; Prader-Willi Syndrome
Unknown
CANNABIDIVARIN
×
Maximum Phase:
2
First Approval:
None
UNII:
I198VBV98I
Molecule Type:
Small molecule
Molecular Formula:
C19H26O2
Molecular Weight:
286.42
AlogP:
5.07
PSA:
40.46
HBD:
2.0
HBA:
#RotB:
4.0
Source:
GSK2881078
2
Small molecule
Investigational
Unknown
Unknown
Cachexia
Androgen Receptor modulator
GSK2881078
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PERFOSFAMIDE
2
Small molecule
Investigational
Unknown
Unknown
Multiple Myeloma; Neuroblastoma
Unknown
PERFOSFAMIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
U880A4FUDA
Molecule Type:
Small molecule
Molecular Formula:
C7H15Cl2N2O4P
Molecular Weight:
293.09
AlogP:
1.7
PSA:
71.03
HBD:
2.0
HBA:
#RotB:
6.0
Source:
SLV-334
2
Small molecule
Investigational
Unknown
Unknown
Brain Injuries
Unknown
SLV-334
×
Maximum Phase:
2
First Approval:
None
UNII:
3613ZP748K
Molecule Type:
Small molecule
Molecular Formula:
C33H36N2O6
Molecular Weight:
556.66
AlogP:
4.97
PSA:
124.01
HBD:
3.0
HBA:
#RotB:
10.0
Source:
CALCIUM PHOSPHATE, TRIBASIC
2
Small molecule
Investigational
Unknown
Unknown
Dental Caries
Unknown
CALCIUM PHOSPHATE, TRIBASIC
×
Maximum Phase:
2
First Approval:
None
UNII:
K4C08XP666
Molecule Type:
Small molecule
Molecular Formula:
Ca3O8P2
Molecular Weight:
310.17
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
BIIB061
2
Small molecule
Investigational
Unknown
Unknown
Multiple Sclerosis
Unknown
BIIB061
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAURINE
2
Small molecule
Investigational
Unknown
Unknown
Homocystinuria; Multiple Sclerosis; Bipolar Disorder; Diabetes Mellitus, Type 2; Mental Disorders; Hypertension
Unknown
TAURINE
×
Maximum Phase:
2
First Approval:
None
UNII:
1EQV5MLY3D
Molecule Type:
Small molecule
Molecular Formula:
C2H7NO3S
Molecular Weight:
125.15
AlogP:
-1.17
PSA:
80.39
HBD:
2.0
HBA:
#RotB:
2.0
Source:
LX-2931
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid
Unknown
LX-2931
×
Maximum Phase:
2
First Approval:
None
UNII:
C5AGI979T7
Molecule Type:
Small molecule
Molecular Formula:
C9H15N3O5
Molecular Weight:
245.24
AlogP:
-1.64
PSA:
142.19
HBD:
6.0
HBA:
#RotB:
5.0
Source:
PLOVAMER ACETATE
2
Small molecule
Investigational
Unknown
Unknown
Multiple Sclerosis, Relapsing-Remitting
HLA class II histocompatibility antigen, DRB1-15 beta chain modulator
PLOVAMER ACETATE
×
Maximum Phase:
2
First Approval:
None
UNII:
5511VZ6NRQ
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INDEGLITAZAR
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus
Peroxisome proliferator-activated receptor agonist
INDEGLITAZAR
×
Maximum Phase:
2
First Approval:
None
UNII:
JMC809G4ZH
Molecule Type:
Small molecule
Molecular Formula:
C19H19NO6S
Molecular Weight:
389.43
AlogP:
2.91
PSA:
94.83
HBD:
1.0
HBA:
#RotB:
7.0
Source:
FUCOXANTHIN
2
Small molecule
Investigational
Unknown
Unknown
Metabolic Syndrome
Unknown
FUCOXANTHIN
×
Maximum Phase:
2
First Approval:
None
UNII:
06O0TC0VSM
Molecule Type:
Small molecule
Molecular Formula:
C40H56O6
Molecular Weight:
632.88
AlogP:
8.14
PSA:
96.36
HBD:
2.0
HBA:
#RotB:
10.0
Source:
DANICOPAN
2
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases; Liver Diseases; Glomerulonephritis, Membranoproliferative; Hemoglobinuria, Paroxysmal
Complement factor D inhibitor
DANICOPAN
×
Maximum Phase:
2
First Approval:
None
UNII:
JM8C1SFX0U
Molecule Type:
Small molecule
Molecular Formula:
C26H23BrFN7O3
Molecular Weight:
580.42
AlogP:
3.74
PSA:
122.97
HBD:
1.0
HBA:
#RotB:
6.0
Source:
RILZABRUTINIB
2
Small molecule
Investigational
Unknown
Unknown
Immunoglobulin G4-Related Disease; Pemphigus; Purpura, Thrombocytopenic, Idiopathic
Tyrosine-protein kinase BTK inhibitor
RILZABRUTINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
5G1WE425BI
Molecule Type:
Small molecule
Molecular Formula:
C36H40FN9O3
Molecular Weight:
665.77
AlogP:
4.42
PSA:
138.66
HBD:
1.0
HBA:
#RotB:
8.0
Source:
ASM-024
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Pulmonary Disease, Chronic Obstructive
Muscarinic acetylcholine receptor M1 antagonist
ASM-024
×
Maximum Phase:
2
First Approval:
None
UNII:
R67KC9COEN
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CAPRAVIRINE
2
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
CAPRAVIRINE
×
Maximum Phase:
2
First Approval:
None
UNII:
VHC779598X
Molecule Type:
Small molecule
Molecular Formula:
C20H20Cl2N4O2S
Molecular Weight:
451.38
AlogP:
5.5
PSA:
83.03
HBD:
1.0
HBA:
#RotB:
7.0
Source:
AFEGOSTAT
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AFEGOSTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
G23AP190YS
Molecule Type:
Small molecule
Molecular Formula:
C6H13NO3
Molecular Weight:
147.17
AlogP:
-2.08
PSA:
72.72
HBD:
4.0
HBA:
#RotB:
1.0
Source:
TROXACITABINE
2
Small molecule
Investigational
Unknown
Unknown
Leukemia
DNA polymerase (alpha/delta/epsilon) inhibitor
TROXACITABINE
×
Maximum Phase:
2
First Approval:
None
UNII:
60KQZ0388Y
Molecule Type:
Small molecule
Molecular Formula:
C8H11N3O4
Molecular Weight:
213.19
AlogP:
-1.31
PSA:
99.6
HBD:
2.0
HBA:
#RotB:
2.0
Source:
NESBUVIR
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C
Unknown
NESBUVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
EYK815W3Z8
Molecule Type:
Small molecule
Molecular Formula:
C22H23FN2O5S
Molecular Weight:
446.5
AlogP:
3.23
PSA:
99.85
HBD:
2.0
HBA:
#RotB:
7.0
Source:
TAK-954
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
TAK-954
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VX-702
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid
MAP kinase p38 alpha inhibitor
VX-702
×
Maximum Phase:
2
First Approval:
None
UNII:
527E7SK68P
Molecule Type:
Small molecule
Molecular Formula:
C19H12F4N4O2
Molecular Weight:
404.32
AlogP:
3.62
PSA:
102.31
HBD:
2.0
HBA:
#RotB:
4.0
Source:
MSDC-0160
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MSDC-0160
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
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PSA