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Total: 6532
Small molecule
Approved
OTHER
INJECTION
Cardiomyopathy, Dilated; Hypertension
Angiotensin-converting enzyme inhibitor
Small molecule
Approved
Unknown
Unknown
Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Coronary Disease; Brain Neoplasms; Aortic Aneurysm, Thoracic; Stroke; Subarachnoid Hemorrhage; Hypertension; Muscle Cramp; Pre-Eclampsia; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Tinea Pedis
Unknown
Small molecule
Approved
Unknown
Unknown
Cocaine-Related Disorders; Parkinson Disease
Unknown
Small molecule
Approved
OTHER
INJECTION
Osteonecrosis; Pruritus; Psychomotor Agitation; Amnesia; Colorectal Neoplasms; Depressive Disorder, Major; Inflammation; Premature Birth; Renal Insufficiency; Scoliosis; Sepsis; Shock; Shock, Septic; Sleep Initiation and Maintenance Disorders; Coronary Disease; Depressive Disorder, Treatment-Resistant; Hypotension; Intestinal Polyps; Leukemia; Lung Neoplasms; Migraine Disorders; Obesity, Morbid; Sleep Apnea, Obstructive; Strabismus; Tonsillitis; Wounds and Injuries; Adenomatous Polyposis Coli; Back Pain; Brain Injuries; Breast Neoplasms; Esophageal Neoplasms; Heart Diseases; Hypertension; Intracranial Aneurysm; Liver Cirrhosis; Neoplasms; Obesity; Pain; Pancreatic Neoplasms; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Status Epilepticus; Stroke; Subarachnoid Hemorrhage
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
Unknown
Unknown
Atrial Fibrillation; Death, Sudden, Cardiac; Heart Failure; Myocardial Infarction; Ventricular Fibrillation; Arrhythmias, Cardiac
Unknown
Small molecule
Approved
Unknown
Unknown
Cystic Fibrosis; Hepatitis C; HIV Infections; Migraine Disorders; Metrorrhagia; Osteoporosis; Neural Tube Defects; Acne Vulgaris
Progesterone receptor agonist
Small molecule
Approved
OTHER
ORAL
Anxiety; Bipolar Disorder; Dementia; Depressive Disorder; Developmental Disabilities; Intellectual Disability; Psychotic Disorders; Schizophrenia
Dopamine D2 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Gliosarcoma; Leukoencephalopathy, Progressive Multifocal; Pneumonia, Viral; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Malaria, Falciparum; Schistosomiasis haematobia; Malaria
Unknown
Small molecule
Approved
Unknown
Unknown
Coronary Artery Disease
Unknown
Small molecule
Approved
EYE; OTHER
IMPLANTATION; OPHTHALMIC; ORAL
Central Nervous System Neoplasms; Kidney Diseases; Melanoma; Mesothelioma; Neuroblastoma; Carcinoma, Hepatocellular; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Glioblastoma; Graft vs Host Disease; Lymphoma; Ovarian Neoplasms; Peritoneal Neoplasms; Conjunctivitis; Cytomegalovirus Infections; Infections; Acquired Immunodeficiency Syndrome; Cytomegalovirus Retinitis; Eye Infections; HIV Infections; Primary Immunodeficiency Diseases; Retinitis; Virus Diseases
Human herpesvirus 1 DNA polymerase inhibitor
Small molecule
Approved
Unknown
Unknown
Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Renal Colic; Diabetic Retinopathy; Hypoxia; Conjunctivitis, Viral; Heart Diseases; Miosis; Osteoarthritis, Knee; Pancreatitis; Periodontitis; Pre-Eclampsia; Retinopathy of Prematurity; Rotator Cuff Injuries; Scoliosis; Tonsillitis; Abdominal Pain; Back Pain; Breast Neoplasms; Cataract; Deglutition Disorders; Headache; Inflammation; Kidney Calculi; Migraine Disorders; Pain; Wounds and Injuries; Eye Diseases; Rheumatic Diseases
Unknown
Small molecule
Unknown
Unknown
Unknown
Pain
Kappa opioid receptor antagonist
Small molecule
Approved
GASTROINTESTINAL; OTHER
ORAL
Pancreatic Neoplasms; Alzheimer Disease; Anemia; Arthritis, Rheumatoid; Carcinoma, Medullary; Central Serous Chorioretinopathy; Child Development Disorders, Pervasive; Chronic Pain; Clostridium Infections; Colitis, Ulcerative; Communicable Diseases; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erectile Dysfunction; Glaucoma; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Laryngomalacia; Melanoma; Mitochondrial Diseases; Muscular Atrophy, Spinal; Neoplasms; Psoriasis; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Cystic Fibrosis; Gastrinoma; Granuloma; Head and Neck Neoplasms; Idiopathic Pulmonary Fibrosis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Ulcer; Zollinger-Ellison Syndrome; Barrett Esophagus; Cough; Cysticercosis; Diabetes Mellitus, Type 1; Dyspepsia; Esophagitis, Peptic; Exocrine Pancreatic Insufficiency; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Multiple Sclerosis, Relapsing-Remitting; Osteoarthritis; Pain; Spondylitis, Ankylosing; Stomach Neoplasms; Wounds and Injuries; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Infections; Peptic Ulcer; Stomach Ulcer
Potassium-transporting ATPase inhibitor
Small molecule
Unknown
Unknown
Unknown
Glaucoma
Unknown
Small molecule
Approved
OTHER
INJECTION; INTRAVENOUS
Inflammation; Ischemia; Leukemia, Lymphocytic, Chronic, B-Cell; Cardiomyopathies; Coronary Disease; Pain; Respiratory Distress Syndrome; ST Elevation Myocardial Infarction; Takotsubo Cardiomyopathy; Angina, Stable; Atrial Fibrillation; Coronary Stenosis; Myocardial Infarction; Neoplasms; Tachycardia, Ventricular; Cardiovascular Diseases; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome
Adenosine receptor agonist
Small molecule
Approved
OTHER
TRANSDERMAL
Schizophrenia; Amphetamine-Related Disorders; Prostatic Neoplasms; Tobacco Use Disorder; Borderline Personality Disorder; Cocaine-Related Disorders; Depressive Disorder; Depressive Disorder, Major; Parkinson Disease
Monoamine oxidase B inhibitor
Small molecule
Approved
Unknown
Unknown
Anxiety; Dementia; Obsessive-Compulsive Disorder; Schizophrenia; Depressive Disorder
Unknown
Small molecule
Approved
Unknown
Unknown
Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Osteomyelitis; Colorectal Neoplasms; Bacterial Infections
Unknown
Small molecule
Approved
OTHER
INJECTION; INTRAVENOUS; IV (INFUSION)
Adenocarcinoma; Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Anus Neoplasms; Appendiceal Neoplasms; Carcinoma, Renal Cell; Carcinoma, Verrucous; Gallbladder Neoplasms; Genital Neoplasms, Female; HIV Infections; Hypopharyngeal Neoplasms; Insulinoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Multiple Myeloma; Pancreatic Neoplasms; Parathyroid Neoplasms; Pericardial Effusion; Pleural Effusion; Skin Diseases; Somatostatinoma; Vaginal Neoplasms; Vulvar Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Brain Stem Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoid Tumor; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Islet Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinosarcoma; Cystadenoma, Serous; Gastrointestinal Stromal Tumors; Glioma; Gliosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Follicular; Myelodysplastic Syndromes; Myeloproliferative Disorders; Oligodendroglioma; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Salivary Gland Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Thrombosis; Thymoma; Ureteral Neoplasms; Wilms Tumor; Adenocarcinoma of Lung; Anemia; Astrocytoma; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Cholangiocarcinoma; Choroid Plexus Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Gestational Trophoblastic Disease; Glioblastoma; Head and Neck Neoplasms; Hepatoblastoma; Hodgkin Disease; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lung Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neuroectodermal Tumors, Primitive; Oropharyngeal Neoplasms; Pain; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retinoblastoma; Retroviridae Infections; Sarcoma; Seminoma; Sex Cord-Gonadal Stromal Tumors; Skin Neoplasms; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Carcinoma, Ovarian Epithelial; Neoplasms; Ovarian Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Hypertension
Sulfonylurea receptor 2, Kir6.2 opener
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Neoplasms; HIV Infections; Liver Abscess; Syphilis; Bacterial Infections; Bronchitis; Bronchitis, Chronic; Gonorrhea; Infections; Otitis Media; Pharyngitis; Tonsillitis; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Adrenal Hyperplasia, Congenital; Ovarian Neoplasms; Polycystic Ovary Syndrome; Prostatic Neoplasms, Castration-Resistant; Carcinoma; Neoplasms; Prostatic Neoplasms
Androgen Receptor antagonist
Small molecule
Approved
OTHER
ORAL
Unknown
Beta-1 adrenergic receptor antagonist
Small molecule
Approved
Unknown
Unknown
Spondylitis, Ankylosing
Unknown
Small molecule
Approved
Unknown
Unknown
Erectile Dysfunction; Substance-Related Disorders; Alcoholism; Cocaine-Related Disorders; Heart Diseases; Stress Disorders, Post-Traumatic; Tobacco Use Disorder; Diabetes Mellitus; Heart Failure; Hypercholesterolemia; Kidney Calculi; Myocardial Infarction; Myocardial Ischemia; Prostatic Hyperplasia; Severe Acute Respiratory Syndrome; Hypertension
Unknown
Small molecule
Approved
Unknown
Unknown
Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Constipation
Neutralises acid
Small molecule
Approved
Unknown
Unknown
Psychotic Disorders
Dopamine D2 receptor antagonist
Small molecule
Approved
OTHER
ORAL
Sleep Initiation and Maintenance Disorders
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
Unknown
Unknown
Blast Crisis; Carcinoma, Hepatocellular; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Neutropenia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Neoplasms
Unknown