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Total: 6532
Small molecule
Approved
Unknown
Unknown
Hypotension, Orthostatic; Orthostatic Intolerance
Unknown
Small molecule
Approved
OTHER
ORAL
Amphetamine-Related Disorders; HIV Infections; Multiple Myeloma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations
Aldehyde dehydrogenase inhibitor
Small molecule
Approved
Unknown
Unknown
Cardiovascular Diseases
Unknown
Small molecule
Approved
OTHER
ORAL
Chondrocalcinosis; Alcoholism; Brain Injuries; Diabetes Mellitus, Type 2; Influenza in Birds; Neoplasms; Cellulitis; Heart Failure; Heart Failure, Systolic; Infections; Obesity; Urinary Tract Infections; Gout
Solute carrier family 22 member 11 inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Histamine H2 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Urinary Bladder, Neurogenic; Digestive System Diseases
Unknown
Small molecule
Approved
OTHER
TOPICAL
Ischemic Stroke; Mucositis; Multiple Sclerosis; Neoplasms; Prostatic Neoplasms; Graves Ophthalmopathy; Myalgia; Thyrotoxicosis; Alzheimer Disease; Chagas Disease; Colorectal Neoplasms; HIV Infections; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Stomatitis; Tuberculosis; Urinary Bladder Neoplasms; Dandruff; Dermatitis, Seborrheic; Pruritus; Tinea
Unknown
Small molecule
Approved
Unknown
Unknown
Obesity; Vascular Diseases; Hypertension; Hypotension, Orthostatic; Infections; Mucositis; Neoplasms; Orthostatic Intolerance; Ovarian Cysts; Pain; Stomatitis; Acute Lung Injury; Bronchiolitis; Cognitive Dysfunction; Mydriasis; Shock, Septic; Stress Disorders, Post-Traumatic; Common Cold; Eye Diseases; Fecal Incontinence; Hypotension; Influenza, Human; Ischemic Stroke; Respiratory Tract Infections; Rhinitis, Allergic, Seasonal; Stroke; Cardiovascular Diseases; Eye Manifestations; Nasal Obstruction
Unknown
Small molecule
Approved
Unknown
Unknown
Hypoglycemia; Obesity; Presbyopia; Mydriasis; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Glucosephosphate Dehydrogenase Deficiency; Obesity; Severe Acute Respiratory Syndrome; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Malaria
Unknown
Small molecule
Approved
OTHER
FOR RX COMPOUNDING; INJECTION; ORAL; RECTAL; TOPICAL; VAGINAL
Fibromyalgia; HIV Infections; Insulin Resistance; Diabetes Mellitus, Type 1; Infections; Lymphoma, Large-Cell, Anaplastic; Obesity; Tobacco Use Disorder; Addison Disease; Adrenal Cortex Neoplasms; Aging; Atrial Fibrillation; Borderline Personality Disorder; Central Nervous System Neoplasms; Conjunctivitis, Allergic; Heart Failure; Leukemia, Mast-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Large B-Cell, Diffuse; Melanoma; Memory Disorders; Multiple Myeloma; Myocardial Infarction; Neoplasms; Opioid-Related Disorders; Phobic Disorders; Wounds and Injuries; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Alcoholism; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Bronchopulmonary Dysplasia; Dermatitis; Eczema; Heart Arrest; Hypotension; Hypoxia; Influenza, Human; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Lymphoma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Oral Submucous Fibrosis; Pneumonia, Viral; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Asthma; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Eye Diseases; Hemorrhoids; Herpes Labialis; Inflammation; Nasal Obstruction; Osteoarthritis; Otitis Externa; Pneumonia
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
INJECTION; ORAL
Osteomyelitis; Melanoma; Acquired Immunodeficiency Syndrome; Diabetic Foot; Tuberculosis, Multidrug-Resistant; Ulcer; HIV Infections; Silicosis; Tuberculosis; Tuberculosis, Pulmonary
Enoyl-[acyl-carrier-protein] reductase inhibitor
Small molecule
Approved
Unknown
Unknown
Arthritis, Rheumatoid; Neoplasms; Adenocarcinoma; Biliary Tract Diseases; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Nasopharyngeal Neoplasms
Unknown
Small molecule
Approved
OTHER
INJECTION; ORAL
Osteomyelitis; Psoriasis; Rheumatic Heart Disease; HIV Infections; Syphilis; Yaws; Bacterial Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Unknown
Unknown
Unknown
Cardiovascular Diseases; Prostatic Neoplasms, Castration-Resistant; Pheochromocytoma
Adrenergic receptor alpha antagonist
Small molecule
Approved
Unknown
Unknown
Bradycardia; Myalgia; Stroke
Unknown
Small molecule
Approved
OTHER
TOPICAL
Unknown
Tyrosinase inhibitor
Small molecule
Approved
Unknown
Unknown
Anemia, Sickle Cell; Constipation; Neck Pain; Osteoarthritis; Myopia; Toothache; Cough; Pain
Unknown
Small molecule
Approved
OTHER
ORAL
Astrocytoma; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Leukemia, Lymphoid; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Amidophosphoribosyltransferase inhibitor
Small molecule
Approved
Unknown
Unknown
Digestive System Diseases
Unknown
Small molecule
Approved
OTHER
SUBCUTANEOUS
Fanconi Anemia; HIV Infections; Inflammation; Leukemia, Plasma Cell; Malaria; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Anemia, Aplastic; Anemia, Sickle Cell; Blast Crisis; Burkitt Lymphoma; Carcinoma, Merkel Cell; Central Serous Chorioretinopathy; Colitis, Ulcerative; Colorectal Neoplasms; Constriction, Pathologic; Coronary Disease; Ependymoma; Fibromatosis, Aggressive; Hematologic Neoplasms; Hemoglobinuria, Paroxysmal; Histiocytosis, Langerhans-Cell; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelomonocytic, Juvenile; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Mesothelioma; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic-Myeloproliferative Diseases; Myocardial Infarction; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteopetrosis; Ovarian Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Schizophrenia; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Urticaria; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Arthritis, Psoriatic; Asthma; Brain Neoplasms; Carcinoma, Squamous Cell; Cardiovascular Diseases; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Crohn Disease; Dermatitis, Atopic; Dermatomyositis; Gestational Trophoblastic Disease; Giant Cell Arteritis; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Head and Neck Neoplasms; Hearing Loss, Sensorineural; Hodgkin Disease; Hydatidiform Mole; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Macular Edema; Medulloblastoma; Multiple Sclerosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive; Osteoarthritis; Osteosarcoma; Pemphigoid, Bullous; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy, Ectopic; Retroperitoneal Fibrosis; Sarcoidosis; Sarcoma; Spondylitis, Ankylosing; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveitis; Uveitis, Intermediate; Vasculitis; Vitiligo; Vitreoretinopathy, Proliferative; Adenoma; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Breast Neoplasms; Choriocarcinoma; Communicable Diseases; Immune System Diseases; Lung Neoplasms; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Mycosis Fungoides; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psoriasis
Dihydrofolate reductase inhibitor
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections; Eye Infections
Bacterial dihydropteroate synthase inhibitor
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections; Cystitis; Urinary Tract Infections
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Chalazion; Osteomyelitis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Burns; Lymphoma, Non-Hodgkin; Candidiasis, Vulvovaginal; Conjunctivitis, Inclusion; Helicobacter Infections; Periodontitis; Vaginosis, Bacterial; Bacterial Infections; Eye Infections; Infections
Bacterial 70S ribosome inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Unknown
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Unknown
Unknown
Unknown
Pain
Unknown
Small molecule
Approved
OTHER
ORAL
Andersen Syndrome; Hypotension, Orthostatic; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures
Carbonic anhydrase II inhibitor
Small molecule
Approved
OTHER
INJECTION; ORAL
Urinary Bladder, Overactive; Peptic Ulcer
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
Unknown
Unknown
Digestive System Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Polycystic Kidney Diseases; Lung Neoplasms; Rectal Neoplasms; Breast Neoplasms; Cerebral Hemorrhage; Heart Diseases; Heart Failure; Neoplasms; Pre-Eclampsia; Stroke; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Ovarian Neoplasms; Uterine Cervical Neoplasms; Hypertension
Unknown
Small molecule
Approved
OTHER
ORAL; SUBLINGUAL
Dementia, Vascular; Cardiovascular Diseases
Adrenergic receptor alpha antagonist
Small molecule
Approved
OTHER
ORAL
Anemia; Cocaine-Related Disorders; Leukemia; Lymphoma; Neuroblastoma; Anemia, Sickle Cell; Optic Neuritis; Pancreatic Neoplasms; Polyneuropathies; Thalassemia; Wounds and Injuries; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
OTHER
INJECTION
Unknown
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Amyotrophic Lateral Sclerosis; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Sandhoff Disease; Tay-Sachs Disease; Toxoplasmosis, Cerebral; Anemia; Chorioretinitis; Depressive Disorder; HIV Infections; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth; Schistosomiasis; Schizophrenia; Toxoplasmosis, Congenital; Malaria; Toxoplasmosis
Dihydrofolate reductase inhibitor