Display Options:
Total: 6532
Small molecule
Approved
Unknown
ORAL
Alcoholism; Borderline Personality Disorder; Alzheimer Disease; Bipolar Disorder; Depressive Disorder; Psychomotor Agitation; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Depressive Disorder, Major; Psychotic Disorders; Schizophrenia
Dopamine D2 receptor partial agonist
Small molecule
Approved
Unknown
Unknown
Carcinoma, Renal Cell; HIV Infections; Leukemia, Myeloid, Acute; Lupus Nephritis; Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Triple Negative Breast Neoplasms; Anemia, Hemolytic, Autoimmune; Hematologic Neoplasms; Leukemia; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Multiple Myeloma; Plasmacytoma; Neoplasms
26S proteasome inhibitor
Small molecule
Approved
Unknown
Unknown
Liver Diseases; Cystic Fibrosis
Cystic fibrosis transmembrane conductance regulator stabiliser
Small molecule
Unknown
Unknown
Unknown
Hepatitis C, Chronic
Nonstructural protein 5A inhibitor
Small molecule
Approved
Unknown
Unknown
Bacterial Infections; Renal Insufficiency; Systemic Inflammatory Response Syndrome; Urinary Tract Infections; Infections; Pneumonia; Pyelonephritis
Unknown
Small molecule
Approved
Unknown
Unknown
Esophageal Neoplasms; Graft vs Host Disease; Liver Diseases; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Carcinoma, Basal Cell; Leukemia; Medulloblastoma; Multiple Myeloma; Neoplasms
Unknown
Small molecule
Approved
Unknown
INHALATION
Bipolar Disorder; Depressive Disorder, Major; Cystic Fibrosis; Severe Acute Respiratory Syndrome; Death, Sudden, Cardiac; Heart Failure; Obsessive-Compulsive Disorder; Pulmonary Disease, Chronic Obstructive; Reperfusion Injury; Stress Disorders, Post-Traumatic; Tinea Pedis; Burns; Colorectal Neoplasms; Keratosis, Actinic; Respiratory Insufficiency
Unknown
Small molecule
Approved
Unknown
Unknown
Hepatitis B, Chronic; Infections; Renal Insufficiency, Chronic; Hepatitis C; Hepatitis C, Chronic; Severe Acute Respiratory Syndrome; Virus Diseases
Unknown
Small molecule
Approved
Unknown
SUBCUTANEOUS
Obesity; Neurofibroma; Lipoma
Cell membrane disrupting agent
Small molecule
Approved
Unknown
Unknown
Hyperkalemia
Potassium chelating agent
Small molecule
Approved
Unknown
ORAL
Hepatitis B, Chronic; HIV Infections
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Small molecule
Approved
Unknown
Unknown
Amyotrophic Lateral Sclerosis; Insulin Resistance; Hepatitis D; Leukemia, Lymphocytic, Chronic, B-Cell; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic; HIV Infections; Severe Acute Respiratory Syndrome; Virus Diseases
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Small molecule
Approved
OTHER
INTRAVENOUS
Renal Insufficiency; Anemia, Iron-Deficiency; Renal Insufficiency, Chronic
Supplement
Small molecule
Unknown
Unknown
Unknown
Glioblastoma; Glioma; Liver Diseases; Carcinoma, Non-Small-Cell Lung; Neoplasms
Unknown
Small molecule
Approved
Unknown
ORAL
Heart Failure, Diastolic; Heart Failure, Systolic; Hypotension; Lymphoma; Multiple Organ Failure; Non-ST Elevated Myocardial Infarction; Aging; Angina, Stable; Atrial Fibrillation; Coronary Disease; Diabetic Nephropathies; Heart Failure; Hypotension, Orthostatic; Mitral Valve Stenosis; Neoplasms; Shock, Septic; Tachycardia; Cardiovascular Diseases
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 blocker
Small molecule
Approved
Unknown
INHALATION
Status Asthmaticus; Pulmonary Disease, Chronic Obstructive
Unknown
Small molecule
Approved
Unknown
ORAL
Prostatic Neoplasms; Sexual Dysfunction, Physiological; Sexual Dysfunctions, Psychological
Unknown
Small molecule
Approved
Unknown
ORAL
Irritable Bowel Syndrome
Mu opioid receptor agonist
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Postoperative Nausea and Vomiting; Nausea
Unknown
Small molecule
Approved
Unknown
ORAL
Melanoma
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
Small molecule
Approved
Unknown
ORAL
Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis
Prostanoid IP receptor agonist
Small molecule
Approved
Unknown
Unknown
Child Development Disorders, Pervasive; Anxiety Disorders; Bipolar Disorder; Depressive Disorder; Depressive Disorder, Major; Schizophrenia; Psychotic Disorders
Unknown
Small molecule
Approved
Unknown
Unknown
Adenocarcinoma; Adenocarcinoma of Lung; Carcinoma; Carcinoma, Squamous Cell; Colorectal Neoplasms; Glioblastoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms
Unknown
Small molecule
Approved
Unknown
INTRAVENOUS
Leukemia, Lymphocytic, Chronic, B-Cell; Sarcoma, Ewing; Breast Neoplasms; Chondrosarcoma, Mesenchymal; Endocrine Gland Neoplasms; Fallopian Tube Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Liposarcoma, Myxoid; Meningioma; Mesothelioma; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Soft Tissue Neoplasms; Ovarian Neoplasms; Sarcoma; Leiomyosarcoma; Liposarcoma; Neoplasms
DNA inhibitor
Small molecule
Unknown
Unknown
Unknown
Carcinoma, Pancreatic Ductal; Esophageal Neoplasms; Leukemia, Myeloid, Acute; Multiple Myeloma; Sarcoma; Skin Neoplasms; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Craniopharyngioma; Leukemia, Myelomonocytic, Chronic; Ovarian Neoplasms; Thyroid Neoplasms; Colorectal Neoplasms; Melanoma; Neoplasms
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
Small molecule
Approved
Unknown
ORAL
Gout; Hyperuricemia
Solute carrier family 22 member 12 inhibitor
Small molecule
Approved
Unknown
Unknown
Anemia, Sickle Cell; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; HIV Infections; Leukemia, Myelomonocytic, Chronic; Liver Neoplasms; Lung Neoplasms; Lymphoma, Mantle-Cell; Melanoma; Nasopharyngeal Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Prostatic Neoplasms; Rectal Neoplasms; Skin Neoplasms; Breast Neoplasms; Carcinoma, Renal Cell; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Glioma; Graft vs Host Disease; Hematologic Neoplasms; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Myelodysplastic Syndromes; Neuroendocrine Tumors; Pancreatic Neoplasms; Plasmacytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Stomach Neoplasms; Thyroid Neoplasms; Waldenstrom Macroglobulinemia; Hodgkin Disease; Multiple Myeloma; Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Blood Coagulation Disorders; Hemorrhage; Ischemic Stroke; Peripheral Arterial Disease; Aortic Valve Stenosis; Atrial Fibrillation; Heart Diseases; Severe Acute Respiratory Syndrome; Stroke; Venous Thromboembolism; Thrombosis
Unknown
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Liver Diseases; Lymphoma; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Adenocarcinoma; Adenocarcinoma, Follicular; Adenocarcinoma of Lung; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Cholangiocarcinoma; Glioma; Meningeal Carcinomatosis; Mesothelioma; Neuroendocrine Tumors; Osteosarcoma; Sarcoma; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Melanoma; Urinary Bladder Neoplasms; Neoplasms; Thyroid Neoplasms
Unknown
Small molecule
Approved
Unknown
ORAL
Carcinoma, Ductal; Carcinoma, Pancreatic Ductal; Glioblastoma; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Kidney Diseases; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Chordoma; Colonic Neoplasms; Endometrial Neoplasms; Liposarcoma; Lymphoma; Lymphoma, Mantle-Cell; Melanoma; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Oligodendroglioma; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Ewing; Thymus Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Sarcoma; Breast Neoplasms; Neoplasms
CDK6/cyclin D1 inhibitor
Small molecule
Approved
Unknown
ORAL
Cholestasis; Obesity; Smith-Lemli-Opitz Syndrome; Barrett Esophagus; Diarrhea; Fatty Liver; Lipodystrophy, Familial Partial; Liver Cirrhosis, Biliary; Non-alcoholic Fatty Liver Disease; Liver Diseases; Peroxisomal Disorders
Unknown
Small molecule
Approved
Unknown
INTRAMUSCULAR
Psychotic Disorders; Autistic Disorder; Bipolar Disorder; Depressive Disorder, Major; Schizophrenia; Tourette Syndrome
Dopamine D2 receptor partial agonist
Small molecule
Approved
Unknown
INTRAVENOUS
Acute Coronary Syndrome; Coronary Disease; ST Elevation Myocardial Infarction; Ischemia; Thrombosis
Unknown