Display Options:
Total: 1496
Small molecule
Approved
OTHER
ORAL
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Chondrocalcinosis; Alcoholism; Brain Injuries; Diabetes Mellitus, Type 2; Influenza in Birds; Neoplasms; Cellulitis; Heart Failure; Heart Failure, Systolic; Infections; Obesity; Urinary Tract Infections; Gout
Solute carrier family 22 member 11 inhibitor
Small molecule
Approved
OTHER
ORAL
Amphetamine-Related Disorders; HIV Infections; Multiple Myeloma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations
Aldehyde dehydrogenase inhibitor
Small molecule
Approved
OTHER
TOPICAL
Unknown
Tyrosinase inhibitor
Small molecule
Approved
OTHER
FOR RX COMPOUNDING; INJECTION; ORAL; RECTAL; TOPICAL; VAGINAL
Fibromyalgia; HIV Infections; Insulin Resistance; Diabetes Mellitus, Type 1; Infections; Lymphoma, Large-Cell, Anaplastic; Obesity; Tobacco Use Disorder; Addison Disease; Adrenal Cortex Neoplasms; Aging; Atrial Fibrillation; Borderline Personality Disorder; Central Nervous System Neoplasms; Conjunctivitis, Allergic; Heart Failure; Leukemia, Mast-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Large B-Cell, Diffuse; Melanoma; Memory Disorders; Multiple Myeloma; Myocardial Infarction; Neoplasms; Opioid-Related Disorders; Phobic Disorders; Wounds and Injuries; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Alcoholism; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Bronchopulmonary Dysplasia; Dermatitis; Eczema; Heart Arrest; Hypotension; Hypoxia; Influenza, Human; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Lymphoma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Oral Submucous Fibrosis; Pneumonia, Viral; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Asthma; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Eye Diseases; Hemorrhoids; Herpes Labialis; Inflammation; Nasal Obstruction; Osteoarthritis; Otitis Externa; Pneumonia
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
INJECTION; ORAL
Osteomyelitis; Melanoma; Acquired Immunodeficiency Syndrome; Diabetic Foot; Tuberculosis, Multidrug-Resistant; Ulcer; HIV Infections; Silicosis; Tuberculosis; Tuberculosis, Pulmonary
Enoyl-[acyl-carrier-protein] reductase inhibitor
Small molecule
Approved
OTHER
INJECTION; ORAL
Osteomyelitis; Psoriasis; Rheumatic Heart Disease; HIV Infections; Syphilis; Yaws; Bacterial Infections
Bacterial penicillin-binding protein inhibitor
Unknown
Approved
OTHER
INJECTION
Adenocarcinoma, Follicular; Thyroid Neoplasms; Head and Neck Neoplasms
Thyroid stimulating hormone receptor agonist
Small molecule
Approved
OTHER
INJECTION; SUBCUTANEOUS
Muscular Dystrophy, Facioscapulohumeral; HIV Wasting Syndrome; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Weight Loss; Hypogonadism
Androgen Receptor agonist
Small molecule
Approved
OTHER
SUBCUTANEOUS
Fanconi Anemia; HIV Infections; Inflammation; Leukemia, Plasma Cell; Malaria; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Anemia, Aplastic; Anemia, Sickle Cell; Blast Crisis; Burkitt Lymphoma; Carcinoma, Merkel Cell; Central Serous Chorioretinopathy; Colitis, Ulcerative; Colorectal Neoplasms; Constriction, Pathologic; Coronary Disease; Ependymoma; Fibromatosis, Aggressive; Hematologic Neoplasms; Hemoglobinuria, Paroxysmal; Histiocytosis, Langerhans-Cell; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelomonocytic, Juvenile; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Mesothelioma; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic-Myeloproliferative Diseases; Myocardial Infarction; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteopetrosis; Ovarian Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Schizophrenia; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Urticaria; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Arthritis, Psoriatic; Asthma; Brain Neoplasms; Carcinoma, Squamous Cell; Cardiovascular Diseases; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Crohn Disease; Dermatitis, Atopic; Dermatomyositis; Gestational Trophoblastic Disease; Giant Cell Arteritis; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Head and Neck Neoplasms; Hearing Loss, Sensorineural; Hodgkin Disease; Hydatidiform Mole; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Macular Edema; Medulloblastoma; Multiple Sclerosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive; Osteoarthritis; Osteosarcoma; Pemphigoid, Bullous; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy, Ectopic; Retroperitoneal Fibrosis; Sarcoidosis; Sarcoma; Spondylitis, Ankylosing; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveitis; Uveitis, Intermediate; Vasculitis; Vitiligo; Vitreoretinopathy, Proliferative; Adenoma; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Breast Neoplasms; Choriocarcinoma; Communicable Diseases; Immune System Diseases; Lung Neoplasms; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Mycosis Fungoides; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psoriasis
Dihydrofolate reductase inhibitor
Small molecule
Approved
OTHER
INJECTION; ORAL
Urinary Bladder, Overactive; Peptic Ulcer
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
OTHER
ORAL
Astrocytoma; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Leukemia, Lymphoid; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Amidophosphoribosyltransferase inhibitor
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections; Cystitis; Urinary Tract Infections
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Andersen Syndrome; Hypotension, Orthostatic; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures
Carbonic anhydrase II inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial dihydropteroate synthase inhibitor
Small molecule
Approved
OTHER
ORAL
Amyotrophic Lateral Sclerosis; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Sandhoff Disease; Tay-Sachs Disease; Toxoplasmosis, Cerebral; Anemia; Chorioretinitis; Depressive Disorder; HIV Infections; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth; Schistosomiasis; Schizophrenia; Toxoplasmosis, Congenital; Malaria; Toxoplasmosis
Dihydrofolate reductase inhibitor
Small molecule
Approved
OTHER
ORAL; SUBLINGUAL
Dementia, Vascular; Cardiovascular Diseases
Adrenergic receptor alpha antagonist
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections; Eye Infections
Bacterial dihydropteroate synthase inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
OTHER
ORAL
Anemia; Cocaine-Related Disorders; Leukemia; Lymphoma; Neuroblastoma; Anemia, Sickle Cell; Optic Neuritis; Pancreatic Neoplasms; Polyneuropathies; Thalassemia; Wounds and Injuries; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
OTHER
INJECTION
Unknown
DNA inhibitor
Small molecule
Approved
CANCER; OTHER
INJECTION; ORAL; TOPICAL
Hematologic Neoplasms; Arthritis, Rheumatoid; Crohn Disease; Epidermolysis Bullosa Acquisita; Pancreatic Neoplasms; Sezary Syndrome; Graft vs Host Disease; Lymphoma; Mycosis Fungoides; Lymphoma, T-Cell; Psoriasis
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Stroke; Epilepsy; Seizures
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
OTHER
INJECTION; ORAL
Acquired Immunodeficiency Syndrome; Anemia; Blast Crisis; Brain Neoplasms; Chordoma; Genetic Diseases, Inborn; HIV Infections; Immunologic Deficiency Syndromes; Liver Neoplasms; Melanoma; Neoplasms, Germ Cell and Embryonal; Osteogenesis Imperfecta; Ovarian Neoplasms; Retinoblastoma; Wiskott-Aldrich Syndrome; X-Linked Combined Immunodeficiency Diseases; Anemia, Sickle Cell; beta-Thalassemia; Breast Neoplasms, Male; Central Nervous System Neoplasms; Epidermolysis Bullosa; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Immune System Diseases; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Juvenile; Leukemia, Plasma Cell; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Lymphoma, AIDS-Related; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Plasmacytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Sandhoff Disease; Severe Combined Immunodeficiency; Signs and Symptoms; Tay-Sachs Disease; Thalassemia; Wolman Disease; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Breast Neoplasms; Graft vs Host Disease; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Sarcoma; Sarcoma, Ewing; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
INTRALYMPHATIC; INTRAUTERINE
Osteoarthritis; Carcinoma, Hepatocellular; Liver Neoplasms; Thrombosis; Neoplasms
Diagnostic agent
Small molecule
Approved
OTHER
ORAL
Unknown
Nematode GABA-A receptor positive modulator
Small molecule
Approved
OTHER
ORAL; TRANSDERMAL
Stress Disorders, Post-Traumatic; Alcoholism; Fatigue; Hypotension, Orthostatic; Neoplasms; Opioid-Related Disorders; Postoperative Complications; Amphetamine-Related Disorders; Brain Injuries; Cocaine-Related Disorders; Feeding and Eating Disorders; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Substance-Related Disorders; Alzheimer Disease; Anemia, Sickle Cell; Anxiety; Asthenia; Bipolar Disorder; Brain Neoplasms; Delirium; Dementia; Depressive Disorder; Depressive Disorder, Major; Hematologic Neoplasms; Multiple Sclerosis; Tobacco Use Disorder; Attention Deficit Disorder with Hyperactivity; Narcolepsy
Dopamine transporter inhibitor
Small molecule
Approved
MUSCULOSKELETAL; OTHER
ORAL
Diabetes Mellitus, Type 2; Esophageal Stenosis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glucose Intolerance; Hematologic Diseases; Inflammation; Lymphoma, B-Cell; Parkinson Disease; Red-Cell Aplasia, Pure; Respiratory Syncytial Virus Infections; Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; AIDS-Associated Nephropathy; Amyotrophic Lateral Sclerosis; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Bell Palsy; Blast Crisis; Burkitt Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Churg-Strauss Syndrome; Embolism, Cholesterol; Gastrointestinal Stromal Tumors; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hearing Loss; Hearing Loss, Sensorineural; Hemangioma; Hemophilia A; Hepatitis, Alcoholic; Hepatitis, Autoimmune; Hepatitis C; HIV Infections; Hypersensitivity; Idiopathic Pulmonary Fibrosis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Kidney Neoplasms; Leukemia, Lymphoid; Lichen Planus, Oral; Lung Diseases; Lung Neoplasms; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasms; Nephritis, Interstitial; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Pneumonia, Viral; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Primary Myelofibrosis; Pulmonary Fibrosis; Purpura, Schoenlein-Henoch; Sarcoma; Stiff-Person Syndrome; Takayasu Arteritis; Thrombocythemia, Essential; Thymus Neoplasms; Vestibular Neuronitis; Alzheimer Disease; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Neoplasms; Cardiomyopathies; Central Nervous System Neoplasms; Cystic Fibrosis; Deafness; Giant Cell Arteritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Heart Failure; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Hypereosinophilic Syndrome; Kidney Diseases; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lupus Nephritis; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Microscopic Polyangiitis; Multiple Myeloma; Muscular Dystrophy, Duchenne; Myasthenia Gravis; Nasal Polyps; Neuroblastoma; Pain; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Purpura, Thrombotic Thrombocytopenic; Renal Insufficiency, Chronic; Retroperitoneal Fibrosis; Rhinitis, Allergic, Perennial; Sarcoidosis, Pulmonary; Sciatica; Severe Acute Respiratory Syndrome; Sinusitis; Tuberculosis; Urticaria; Uveitis; Uveitis, Intermediate; Vasculitis; Waldenstrom Macroglobulinemia; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Berylliosis; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Dermatomyositis; Erythema Multiforme; Herpes Zoster Ophthalmicus; Hypercalcemia; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Pneumonia; Polymyositis; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Unknown
Dopamine D2 receptor antagonist
Small molecule
Approved
OTHER
ORAL
Unknown
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
OTHER
RECTAL
Cardiotoxicity; Genital Neoplasms, Female; Headache; Migraine Disorders; Nausea; Anxiety; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
Dopamine D2 receptor antagonist
Small molecule
Approved
OTHER
ORAL
Breast Neoplasms; Hypogonadism; Neoplasms; Orchitis
Androgen Receptor agonist
Small molecule
Approved
OTHER
ORAL
Hypertension
Synaptic vesicular amine transporter inhibitor
Small molecule
Approved
OTHER
RECTAL
Delirium; Glioblastoma; Neonatal Abstinence Syndrome; Severe Acute Respiratory Syndrome; Conduct Disorder; Porphyrias; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
D2-like dopamine receptor antagonist
Small molecule
Approved
OTHER
OPHTHALMIC
Glaucoma
Acetylcholinesterase inhibitor