Display Options:
Total: 1496
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Chronic Pain; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Fractures, Bone; Rhinitis, Allergic, Perennial
Histamine H1 receptor antagonist
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PREGNANCY AND GYNECOLOGY
ORAL; VAGINAL
Atrophy; Menopause
Estrogen receptor agonist
Protein
Approved
OTHER
SINGLE-USE
Psoriasis; Cystic Fibrosis; Leukemia; Lymphoma, Non-Hodgkin; Neuroblastoma; Osteosarcoma; Prostatic Neoplasms, Castration-Resistant; Retinal Degeneration; Rhabdomyosarcoma; Sarcoma, Ewing; Uveitis; Uveitis, Anterior; Xerostomia; Arthritis, Reactive; Bronchiolitis Obliterans; Fallopian Tube Neoplasms; Friedreich Ataxia; Hepatitis C, Chronic; HIV Infections; Leukocyte-Adhesion Deficiency Syndrome; Liver Cirrhosis; Meningitis, Cryptococcal; Mesothelioma; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycosis Fungoides; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Breast Neoplasms; Candidemia; Idiopathic Pulmonary Fibrosis; Lymphoma; Melanoma; Pulmonary Fibrosis; Granulomatous Disease, Chronic; Osteopetrosis
Interferon gamma receptor agonist
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Amphetamine-Related Disorders; Gastrointestinal Stromal Tumors; Epilepsy; Obesity; Cocaine-Related Disorders; Parkinson Disease
Catechol O-methyltransferase inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
HIV Infections; Central Nervous System Neoplasms; Head and Neck Neoplasms; Heart Failure; Leukoplakia, Oral; Non-alcoholic Fatty Liver Disease; Pituitary ACTH Hypersecretion; Sarcoma; Atherosclerosis; Insulin Resistance; Diabetes Mellitus; Diabetes Mellitus, Type 2
Peroxisome proliferator-activated receptor gamma agonist
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY
INJECTION; ORAL
Neoplasms; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic
Vitamin D receptor agonist
Small molecule
Approved
CANCER; OTHER
INTRAVENOUS; ORAL
Desmoplastic Small Round Cell Tumor; Cytomegalovirus Infections; Ependymoma; Fallopian Tube Neoplasms; Meningitis, Aseptic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Biliary Tract Neoplasms; Brain Diseases; Brain Stem Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Colorectal Neoplasms; Ganglioneuroblastoma; Gastrointestinal Stromal Tumors; Glioma; Hereditary Breast and Ovarian Cancer Syndrome; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Medulloblastoma; Myelodysplastic Syndromes; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Neurofibromatosis 1; Ovarian Neoplasms; Pancreatic Neoplasms; Pinealoma; Pituitary Neoplasms; Rectal Neoplasms; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Spinal Cord Neoplasms; Astrocytoma; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Diffuse Intrinsic Pontine Glioma; Gliosarcoma; Melanoma; Neoplasm Metastasis; Neuroendocrine Tumors; Oligodendroglioma; Optic Nerve Glioma; Sarcoma, Ewing; Glioblastoma; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
ORAL
Long QT Syndrome; Heart Failure; Arrhythmias, Cardiac; Atrial Fibrillation
HERG blocker
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases
Human immunodeficiency virus type 1 protease inhibitor
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Osteomyelitis; Cataract; Tuberculosis; Bacterial Infections; Conjunctivitis, Bacterial; Eye Infections; Infections
DNA gyrase inhibitor
Small molecule
Approved
OTHER
INJECTION
Unknown
Diagnostic agent
Protein
Approved
CARDIOVASCULAR; OTHER
INJECTION; INTRAVENOUS
Venous Thrombosis; Acute Coronary Syndrome; Acute Disease; Aortic Valve Stenosis; Cardiovascular Diseases; Coronary Disease; Heart Diseases; Hematologic Diseases; Hemorrhage; Myocardial Infarction; Subarachnoid Hemorrhage; Angina, Unstable; Syndrome; Thrombocytopenia; Thrombosis
Thrombin inhibitor
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS
ORAL
Neoplasms; Multiple Sclerosis; Aggression; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Neuralgia; Psychomotor Agitation; Schizophrenia; Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
OTHER
ORAL
Diabetes Mellitus; Diabetes Mellitus, Type 2
Sulfonylurea receptor 1, Kir6.2 blocker
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Carcinoma, Intraductal, Noninfiltrating; Tobacco Use Disorder; Anxiety; Breast Neoplasms, Male; Diabetes Mellitus; Persian Gulf Syndrome; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Adenomyosis; Alcoholism; Alzheimer Disease; Bipolar Disorder; Borderline Personality Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Serous Chorioretinopathy; Cocaine-Related Disorders; Endometrial Neoplasms; Endometriosis; Fallopian Tube Neoplasms; Hepatitis C; HIV Infections; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Stress Disorders, Post-Traumatic; Abortion, Spontaneous; Depressive Disorder; Depressive Disorder, Major; Leiomyoma; Meningioma; Pituitary ACTH Hypersecretion; Cushing Syndrome
Glucocorticoid receptor antagonist
Protein
Approved
OTHER; PREGNANCY AND GYNECOLOGY
INJECTION
Arthritis, Rheumatoid; Endometriosis; Infertility; Ovarian Hyperstimulation Syndrome; Prostatic Hyperplasia
Unknown
Small molecule
Approved
MUSCULOSKELETAL; OTHER
ORAL
Lupus Erythematosus, Systemic; Dysmenorrhea; Pharyngitis; Toothache; Low Back Pain; Migraine Disorders; Pain; Prostatic Neoplasms; Shoulder Pain; Spondylitis, Ankylosing; Tuberculosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases
Cyclooxygenase-2 inhibitor
Enzyme
Approved
OTHER
UNKNOWN
Respiratory Distress Syndrome; Brain Ischemia; Cerebral Infarction; Nervous System Diseases; Pleural Effusion; Death, Sudden, Cardiac; Ischemic Stroke; Pulmonary Embolism; Retinal Artery Occlusion; ST Elevation Myocardial Infarction; Stroke; Myocardial Infarction; Thrombosis
Plasminogen activator
Small molecule
Approved
OTHER
INTRAVENOUS; ORAL
Burns; Cystic Fibrosis; Meningitis; Abscess; Cellulitis; Gram-Positive Bacterial Infections; Optic Nerve Diseases; Pneumonia, Bacterial; Pneumonia, Pneumococcal; Skin Diseases; Staphylococcal Infections; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Bacteremia; Bacterial Infections; Infections; Osteomyelitis; Pneumonia
Bacterial 70S ribosome inhibitor
Small molecule
Approved
HEMATOLOGY; OTHER; UROLOGY AND KIDNEY
INTRAVENOUS
Renal Insufficiency; Hematologic Neoplasms; Hypertension, Pulmonary; Anemia; Anemia, Iron-Deficiency; Renal Insufficiency, Chronic
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Cocaine-Related Disorders; Hearing Loss, Noise-Induced; Tobacco Use Disorder; Essential Tremor; Hearing Loss; Migraine Disorders; Obesity; Parkinson Disease; Alcoholism; Epilepsy, Complex Partial; Feeding and Eating Disorders; Psychotic Disorders; Schizophrenia; Smoking Cessation; Weight Gain; Epilepsy; Seizures
Sodium channel alpha subunit blocker
Protein
Approved
OTHER
INJECTION; SUBCUTANEOUS
Diabetic Retinopathy; Atherosclerosis; Coronary Disease; Cystic Fibrosis; Hypercholesterolemia; Hyperglycemia; Hypertension; Leukemia; Lymphoma; Myocardial Infarction; Prediabetic State; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2
Insulin receptor agonist
Small molecule
Approved
CARDIOVASCULAR; HEMATOLOGY; OTHER
INJECTION; INTRAVENOUS
Angina, Unstable; Ischemic Stroke; Thrombocytopenia; Thrombosis
Thrombin inhibitor
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
TRANSDERMAL
Amphetamine-Related Disorders; Cocaine-Related Disorders; Down Syndrome; Substance-Related Disorders; Anxiety; Brain Injuries; Cognitive Dysfunction; Delirium; Dementia, Vascular; Depressive Disorder; Neurobehavioral Manifestations; Schizophrenia; Supranuclear Palsy, Progressive; Alzheimer Disease; Dementia; Parkinson Disease
Cholinesterases; ACHE & BCHE inhibitor
Small molecule
Approved
EYE; OTHER
OPHTHALMIC; TOPICAL
Vitiligo; Alopecia; Graves Ophthalmopathy; Glaucoma; Glaucoma, Open-Angle; Hypotrichosis; Ocular Hypertension
Prostanoid FP receptor agonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
ORAL
Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Non-Small-Cell Lung; Common Cold; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Eczema; Pruritus; Rhinitis, Allergic, Perennial; Hypersensitivity; Rhinitis, Allergic, Seasonal; Urticaria
Histamine H1 receptor antagonist
Protein
Approved
OTHER
INTRAVENOUS; SUBCUTANEOUS
Acute Kidney Injury; Brain Injuries; Brain Ischemia; Dysgerminoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Breast Neoplasms; Kidney Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Myocardial Infarction; Small Cell Lung Carcinoma; Anemia; Neoplasms; Renal Insufficiency, Chronic
Erythropoietin receptor agonist
Antibody
Approved
CANCER; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
INJECTION; INTRAVENOUS
Neoplasms, Neuroepithelial; Anemia; Arthritis, Rheumatoid; Fallopian Tube Neoplasms; Fanconi Anemia; Kidney Diseases; Leukemia, Prolymphocytic, T-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Renal Insufficiency; Vasculitis; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; beta-Thalassemia; Crohn Disease; Diabetes Mellitus, Type 1; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis; Hodgkin Disease; Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphoid; Leukemia, Prolymphocytic; Liver Diseases; Lymphoma, Large B-Cell, Diffuse; Mycosis Fungoides; Myeloproliferative Disorders; Myositis, Inclusion Body; Neoplasms; Osteopetrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Severe Combined Immunodeficiency; Sezary Syndrome; Thalassemia; Waldenstrom Macroglobulinemia; Anemia, Sickle Cell; Granuloma, Lethal Midline; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, T-Cell, Peripheral; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Sclerosis
CAMPATH-1 antigen inhibitor
Small molecule
Approved
OTHER
INTRAVENOUS
Breast Neoplasms; Ischemic Stroke; Myocardial Infarction
Diagnostic agent
Protein
Approved
DERMATOLOGY; OTHER
UNKNOWN
Carcinoma, Renal Cell; Fallopian Tube Neoplasms; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Astrocytoma; Carcinoid Tumor; Carcinoma, Squamous Cell; Cholangiocarcinoma; Craniopharyngioma; Glioma; Head and Neck Neoplasms; Hematologic Neoplasms; HIV Infections; Kidney Neoplasms; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Neurofibroma, Plexiform; Neurofibromatosis 1; Skin Neoplasms; Uterine Cervical Neoplasms; Acquired Immunodeficiency Syndrome; Carcinoma, Hepatocellular; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Hepatitis D; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Cirrhosis; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasm Metastasis; Osteosarcoma; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Hepatitis C, Chronic; Melanoma
Interferon alpha/beta receptor agonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Urinary Tract Infections; Bronchitis, Chronic; Infections; Pharyngitis; Tonsillitis
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER
ORAL
Cystic Fibrosis; Diabetes Mellitus, Type 2; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Infertility, Female; Leukemia, Lymphocytic, Chronic, B-Cell; Non-alcoholic Fatty Liver Disease; Bulimia; Bulimia Nervosa; Depressive Disorder; Endometrial Neoplasms; Hidradenitis Suppurativa; Hyperandrogenism; Metrorrhagia; Osteoporosis; Premenstrual Syndrome; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Migraine Disorders; Neural Tube Defects; Polycystic Ovary Syndrome; Pregnancy; Turner Syndrome; Acne Vulgaris; Neoplasms
Estrogen receptor alpha agonist
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Exfoliation Syndrome; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension
Prostanoid FP receptor agonist
Small molecule
Approved
OTHER; PREGNANCY AND GYNECOLOGY
ORAL
Osteoarthritis, Knee; Pancreatitis; Osteoarthritis; Pain; Pharyngitis; Rheumatic Diseases
Cyclooxygenase-2 inhibitor
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Aging; Amyotrophic Lateral Sclerosis; Bulbo-Spinal Atrophy, X-Linked; Prostatitis; Severe Acute Respiratory Syndrome; Alopecia; Hypogonadism; Prostatic Neoplasms, Castration-Resistant; Prostatic Hyperplasia; Prostatic Neoplasms
Steroid 5-alpha-reductase inhibitor