DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 92


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Neoplasms; Multiple Sclerosis; Aggression; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Neuralgia; Psychomotor Agitation; Schizophrenia; Epilepsy; Seizures Sodium channel alpha subunit blocker


Small molecule Approved OTHER INTRAMUSCULAR; ORAL; ORALLY DISINTEGRATING Amphetamine-Related Disorders; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Fragile X Syndrome; Obsessive-Compulsive Disorder; Trichotillomania; Alcoholism; Alzheimer Disease; Anorexia Nervosa; Anxiety; Child Development Disorders, Pervasive; Dementia; Depression, Postpartum; Mental Disorders; Stress Disorders, Post-Traumatic; Tic Disorders; Aggression; Autistic Disorder; Bipolar Disorder; Depressive Disorder; Depressive Disorder, Major; Psychomotor Agitation; Psychotic Disorders; Schizophrenia; Tourette Syndrome Dopamine D2 receptor partial agonist

Small molecule

Approved

OTHER

INTRAMUSCULAR; ORAL; ORALLY DISINTEGRATING

Amphetamine-Related Disorders; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Fragile X Syndrome; Obsessive-Compulsive Disorder; Trichotillomania; Alcoholism; Alzheimer Disease; Anorexia Nervosa; Anxiety; Child Development Disorders, Pervasive; Dementia; Depression, Postpartum; Mental Disorders; Stress Disorders, Post-Traumatic; Tic Disorders; Aggression; Autistic Disorder; Bipolar Disorder; Depressive Disorder; Depressive Disorder, Major; Psychomotor Agitation; Psychotic Disorders; Schizophrenia; Tourette Syndrome

Dopamine D2 receptor partial agonist


Small molecule Approved CANCER; GASTROINTESTINAL; OTHER INTRAVENOUS; ORAL Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting Neurokinin 1 receptor antagonist

Small molecule

Approved

CANCER; GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting

Neurokinin 1 receptor antagonist


Small molecule Approved OTHER ORAL Diarrhea; Neuronal Ceroid-Lipofuscinoses; Cystic Fibrosis; HIV Infections; Spastic Paraplegia, Hereditary; Gangliosidoses, GM2; Glycogen Storage Disease; Niemann-Pick Disease, Type C; Sandhoff Disease; Gaucher Disease; Glycogen Storage Disease Type II; Niemann-Pick Diseases Ceramide glucosyltransferase inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Marijuana Abuse; Anxiety Disorders; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved EMERGENCY MEDICINE; MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Carcinoma, Squamous Cell; Cough; Essential Tremor; Marijuana Abuse; Oropharyngeal Neoplasms; Pregnancy; Refractive Errors; Tobacco Use Disorder; Alcoholism; Complex Regional Pain Syndromes; Dental Anxiety; Diabetes Mellitus; Dry Eye Syndromes; Irritable Bowel Syndrome; Nausea; Pancreatitis, Chronic; Pruritus; Urinary Bladder, Overactive; Anxiety; Breast Neoplasms; Burning Mouth Syndrome; Chronic Pain; Dementia; Depressive Disorder; Diabetic Neuropathies; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Fractures, Bone; Headache; Herpes Zoster; Intervertebral Disc Degeneration; Migraine Disorders; Mononeuropathies; Muscle Cramp; Neuralgia, Postherpetic; Neurotic Disorders; Opioid-Related Disorders; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Prostatitis; Radiculopathy; Restless Legs Syndrome; Schizophrenia; Sleep Initiation and Maintenance Disorders; Anxiety Disorders; Epilepsy; Fibromyalgia; Neuralgia; Seizures; Spinal Cord Injuries Voltage-gated calcium channel modulator

Small molecule

Approved

EMERGENCY MEDICINE; MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Carcinoma, Squamous Cell; Cough; Essential Tremor; Marijuana Abuse; Oropharyngeal Neoplasms; Pregnancy; Refractive Errors; Tobacco Use Disorder; Alcoholism; Complex Regional Pain Syndromes; Dental Anxiety; Diabetes Mellitus; Dry Eye Syndromes; Irritable Bowel Syndrome; Nausea; Pancreatitis, Chronic; Pruritus; Urinary Bladder, Overactive; Anxiety; Breast Neoplasms; Burning Mouth Syndrome; Chronic Pain; Dementia; Depressive Disorder; Diabetic Neuropathies; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Fractures, Bone; Headache; Herpes Zoster; Intervertebral Disc Degeneration; Migraine Disorders; Mononeuropathies; Muscle Cramp; Neuralgia, Postherpetic; Neurotic Disorders; Opioid-Related Disorders; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Prostatitis; Radiculopathy; Restless Legs Syndrome; Schizophrenia; Sleep Initiation and Maintenance Disorders; Anxiety Disorders; Epilepsy; Fibromyalgia; Neuralgia; Seizures; Spinal Cord Injuries

Voltage-gated calcium channel modulator


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Neuralgia; Epilepsy; Dementia; Depressive Disorder; Epilepsia Partialis Continua; Low Back Pain; Pain; Schizophrenia; Anxiety; Lennox Gastaut Syndrome; Seizures GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Marijuana Abuse; Burns; Migraine with Aura; Migraine without Aura; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Substance-Related Disorders; Tobacco Use Disorder; Bipolar Disorder; Depressive Disorder; Sleep Wake Disorders; Sleep Initiation and Maintenance Disorders Melatonin receptor agonist

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Marijuana Abuse; Burns; Migraine with Aura; Migraine without Aura; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Substance-Related Disorders; Tobacco Use Disorder; Bipolar Disorder; Depressive Disorder; Sleep Wake Disorders; Sleep Initiation and Maintenance Disorders

Melatonin receptor agonist


Small molecule Approved Unknown ORAL Alzheimer Disease; Amyotrophic Lateral Sclerosis; Restless Legs Syndrome; Supranuclear Palsy, Progressive; Parkinson Disease Unknown


Small molecule Approved OTHER ORAL Alcohol Drinking; Alzheimer Disease; Amphetamine-Related Disorders; Cocaine-Related Disorders; Friedreich Ataxia; Machado-Joseph Disease; Marijuana Abuse; Parkinson Disease; Psychotic Disorders; Schizophrenia; Substance-Related Disorders; Acute Coronary Syndrome; Alcoholism; Dry Eye Syndromes; Lung Neoplasms; Neoplasms; Smoking Cessation; Eye Diseases; Tobacco Use Disorder Neuronal acetylcholine receptor; alpha4/beta2 partial agonist

Small molecule

Approved

OTHER

ORAL

Alcohol Drinking; Alzheimer Disease; Amphetamine-Related Disorders; Cocaine-Related Disorders; Friedreich Ataxia; Machado-Joseph Disease; Marijuana Abuse; Parkinson Disease; Psychotic Disorders; Schizophrenia; Substance-Related Disorders; Acute Coronary Syndrome; Alcoholism; Dry Eye Syndromes; Lung Neoplasms; Neoplasms; Smoking Cessation; Eye Diseases; Tobacco Use Disorder

Neuronal acetylcholine receptor; alpha4/beta2 partial agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Obsessive-Compulsive Disorder; Anxiety; Autistic Disorder; Bipolar Disorder; Dementia; Depressive Disorder; Mood Disorders; Psychotic Disorders; Schizophrenia Dopamine D2 receptor antagonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Pain; Epilepsy; Lennox Gastaut Syndrome; Seizures Sodium channel alpha subunit blocker


Small molecule Approved Unknown ORAL Back Pain; Chronic Pain; Diabetic Neuropathies; Hallux Valgus; Joint Diseases; Low Back Pain; Neoplasms; Neuralgia; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Unknown


Small molecule Approved MUSCULOSKELETAL; OTHER ORAL Tourette Syndrome; Movement Disorders; Chorea; Huntington Disease Synaptic vesicular amine transporter inhibitor


Small molecule Approved OTHER ORAL Fibromyalgia; Hepatitis C, Chronic; Depressive Disorder; Depressive Disorder, Major Norepinephrine transporter inhibitor


Small molecule Approved OTHER; PEDIATRICS ORAL Tourette Syndrome; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Obesity; Tuberous Sclerosis; Epilepsies, Partial; Epilepsy; Epilepsy, Complex Partial; Spasms, Infantile Gamma-amino-N-butyrate transaminase inhibitor


Small molecule Approved OTHER ORAL Liver Diseases; Stress Disorders, Post-Traumatic; Bipolar Disorder; Psychotic Disorders; Schizophrenia Dopamine D2 receptor antagonist


Small molecule Approved Unknown SUBLINGUAL; TRANSDERMAL Bipolar Disorder; Psychotic Disorders; Schizophrenia Unknown


Small molecule Approved MUSCULOSKELETAL ORAL Astrocytoma; Breast Neoplasms; Cerebral Hemorrhage; Glioblastoma; Renal Insufficiency; Rett Syndrome; Asthma; Optic Neuritis; Schizophrenia; Severe Acute Respiratory Syndrome; Stroke; Uveitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Unknown

Small molecule

Approved

MUSCULOSKELETAL

ORAL

Astrocytoma; Breast Neoplasms; Cerebral Hemorrhage; Glioblastoma; Renal Insufficiency; Rett Syndrome; Asthma; Optic Neuritis; Schizophrenia; Severe Acute Respiratory Syndrome; Stroke; Uveitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Unknown


Small molecule Approved MUSCULOSKELETAL ORAL Cerebral Palsy; Motor Neuron Disease; Optic Neuritis; Renal Insufficiency; Carpal Tunnel Syndrome; Guillain-Barre Syndrome; Memory, Short-Term; Muscular Atrophy, Spinal; Prostatic Diseases; Sleep Apnea, Obstructive; Trauma, Nervous System; Wounds and Injuries; Ischemic Stroke; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle Spasticity; Spinal Cord Injuries; Stroke; Multiple Sclerosis Voltage-gated potassium channel blocker

Small molecule

Approved

MUSCULOSKELETAL

ORAL

Cerebral Palsy; Motor Neuron Disease; Optic Neuritis; Renal Insufficiency; Carpal Tunnel Syndrome; Guillain-Barre Syndrome; Memory, Short-Term; Muscular Atrophy, Spinal; Prostatic Diseases; Sleep Apnea, Obstructive; Trauma, Nervous System; Wounds and Injuries; Ischemic Stroke; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle Spasticity; Spinal Cord Injuries; Stroke; Multiple Sclerosis

Voltage-gated potassium channel blocker


Small molecule Approved OTHER; UROLOGY AND KIDNEY ORAL Esophageal Achalasia; Kidney Diseases; Liver Diseases; Polycystic Ovary Syndrome; Cerebral Hemorrhage; Heart Failure; Hypertrophy, Left Ventricular; Pain; Prediabetic State; Urinary Bladder, Neurogenic; Cystitis, Interstitial; Kidney Calculi; Polyuria; Urinary Bladder, Overactive; Urinary Incontinence; Urinary Incontinence, Urge Beta-3 adrenergic receptor agonist

Small molecule

Approved

OTHER; UROLOGY AND KIDNEY

ORAL

Esophageal Achalasia; Kidney Diseases; Liver Diseases; Polycystic Ovary Syndrome; Cerebral Hemorrhage; Heart Failure; Hypertrophy, Left Ventricular; Pain; Prediabetic State; Urinary Bladder, Neurogenic; Cystitis, Interstitial; Kidney Calculi; Polyuria; Urinary Bladder, Overactive; Urinary Incontinence; Urinary Incontinence, Urge

Beta-3 adrenergic receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INTRAVENOUS; ORAL Amyotrophic Lateral Sclerosis; Kidney Diseases; Alcoholism; Brain Neoplasms; Fibromyalgia; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis; Paraganglioma; Anxiety; Dementia; Depressive Disorder; Diabetic Neuropathies; Erythromelalgia; Migraine Disorders; Schizophrenia; Sciatica; Status Epilepticus; Epilepsies, Partial; Epilepsy; Seizures Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INTRAVENOUS; ORAL

Amyotrophic Lateral Sclerosis; Kidney Diseases; Alcoholism; Brain Neoplasms; Fibromyalgia; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis; Paraganglioma; Anxiety; Dementia; Depressive Disorder; Diabetic Neuropathies; Erythromelalgia; Migraine Disorders; Schizophrenia; Sciatica; Status Epilepticus; Epilepsies, Partial; Epilepsy; Seizures

Sodium channel alpha subunit blocker