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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
PHENFORMIN
1
Small molecule
Investigational
Unknown
Unknown
Melanoma; Diabetes Mellitus
Unknown
PHENFORMIN
×
Maximum Phase:
1
First Approval:
None
UNII:
DD5K7529CE
Molecule Type:
Small molecule
Molecular Formula:
C10H15N5
Molecular Weight:
205.26
AlogP:
0.24
PSA:
97.78
HBD:
5.0
HBA:
#RotB:
3.0
Source:
PTI-6D2
1
Antibody
Investigational
Unknown
Unknown
Melanoma
Melanin binding agent
PTI-6D2
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LU AF82422
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LU AF82422
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BLXA4
1
Small molecule
Investigational
Unknown
Unknown
Inflammation
Unknown
BLXA4
×
Maximum Phase:
1
First Approval:
None
UNII:
LXE89WJ787
Molecule Type:
Small molecule
Molecular Formula:
C22H32O5
Molecular Weight:
376.49
AlogP:
3.63
PSA:
97.99
HBD:
4.0
HBA:
#RotB:
13.0
Source:
NARNATUMAB
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Macrophage-stimulating protein receptor inhibitor
NARNATUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
R42YK40U9M
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HIP2B
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
HIP2B
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SEVITERONEL
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Breast Neoplasms, Male; Neoplasms; Prostatic Neoplasms, Castration-Resistant
Unknown
SEVITERONEL
×
Maximum Phase:
1
First Approval:
None
UNII:
8S5OIN36X4
Molecule Type:
Small molecule
Molecular Formula:
C18H17F4N3O3
Molecular Weight:
399.34
AlogP:
4.05
PSA:
80.26
HBD:
2.0
HBA:
#RotB:
7.0
Source:
AGN-201904
1
Small molecule
Investigational
Unknown
Unknown
Peptic Ulcer
Unknown
AGN-201904
×
Maximum Phase:
1
First Approval:
None
UNII:
G0835O03ZM
Molecule Type:
Small molecule
Molecular Formula:
C25H25N3O8S2
Molecular Weight:
559.62
AlogP:
3.07
PSA:
146.91
HBD:
1.0
HBA:
#RotB:
10.0
Source:
GSK-625433
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GSK-625433
×
Maximum Phase:
1
First Approval:
None
UNII:
2YAD6KT0NT
Molecule Type:
Small molecule
Molecular Formula:
C26H32N4O5S
Molecular Weight:
512.63
AlogP:
4.02
PSA:
106.78
HBD:
1.0
HBA:
#RotB:
8.0
Source:
TRV-120027
1
Protein
Investigational
Unknown
Unknown
Heart Failure; Severe Acute Respiratory Syndrome
Unknown
TRV-120027
×
Maximum Phase:
1
First Approval:
None
UNII:
J1J4P3PQZD
Molecule Type:
Protein
Molecular Formula:
C43H67N13O10
Molecular Weight:
926.09
AlogP:
-1.91
PSA:
355.05
HBD:
13.0
HBA:
#RotB:
26.0
Source:
MIRZOTAMAB CLEZUTOCLAX
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Unknown
MIRZOTAMAB CLEZUTOCLAX
×
Maximum Phase:
1
First Approval:
None
UNII:
TY49T0B03B
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MITAZALIMAB
1
Antibody
Investigational
Unknown
Unknown
Carcinoma, Pancreatic Ductal; Neoplasms
Unknown
MITAZALIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
Q9J81E7VFM
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ASP-4058
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ASP-4058
×
Maximum Phase:
1
First Approval:
None
UNII:
01J7526K2Q
Molecule Type:
Small molecule
Molecular Formula:
C19H12F6N4O2
Molecular Weight:
442.32
AlogP:
5.63
PSA:
76.83
HBD:
1.0
HBA:
#RotB:
4.0
Source:
XL-844
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Neoplasms
Serine/threonine-protein kinase Chk1 inhibitor
XL-844
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RG-7603
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin
Serine/threonine-protein kinase mTOR inhibitor
RG-7603
×
Maximum Phase:
1
First Approval:
None
UNII:
579255I6O9
Molecule Type:
Small molecule
Molecular Formula:
C24H32N6O3
Molecular Weight:
452.56
AlogP:
2.27
PSA:
91.85
HBD:
2.0
HBA:
#RotB:
5.0
Source:
NEOSAXITOXIN
1
Small molecule
Investigational
Unknown
Unknown
Pain
Unknown
NEOSAXITOXIN
×
Maximum Phase:
1
First Approval:
None
UNII:
6YRL8BWD9H
Molecule Type:
Small molecule
Molecular Formula:
C10H17N7O5
Molecular Weight:
315.29
AlogP:
-3.54
PSA:
193.75
HBD:
7.0
HBA:
#RotB:
2.0
Source:
SNS-062
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SNS-062
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK2879552
1
Small molecule
Investigational
Unknown
Unknown
Leukemia; Myelodysplastic Syndromes; Small Cell Lung Carcinoma
Unknown
GSK2879552
×
Maximum Phase:
1
First Approval:
None
UNII:
GT77Z6Y09Z
Molecule Type:
Small molecule
Molecular Formula:
C23H28N2O2
Molecular Weight:
364.49
AlogP:
3.74
PSA:
52.57
HBD:
2.0
HBA:
#RotB:
7.0
Source:
IRL-1620
1
Protein
Investigational
Unknown
Unknown
Unknown
Unknown
IRL-1620
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
N-HYDROXY-NOR-ARGININE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
N-HYDROXY-NOR-ARGININE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BPN-14967
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BPN-14967
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK-1795091
1
Unknown
Investigational
Unknown
Unknown
Neoplasms
Unknown
GSK-1795091
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TEMANOGREL
1
Small molecule
Investigational
Unknown
Unknown
Acute Coronary Syndrome
Serotonin 2a (5-HT2a) receptor inverse agonist
TEMANOGREL
×
Maximum Phase:
1
First Approval:
None
UNII:
F42Z27575A
Molecule Type:
Small molecule
Molecular Formula:
C24H28N4O4
Molecular Weight:
436.51
AlogP:
3.06
PSA:
77.85
HBD:
1.0
HBA:
#RotB:
8.0
Source:
VEBRELTINIB
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Unknown
VEBRELTINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C20H15F3N8
Molecular Weight:
424.39
AlogP:
3.49
PSA:
78.72
HBD:
0.0
HBA:
#RotB:
4.0
Source:
HMN-214
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Serine/threonine-protein kinase PLK1 inhibitor
HMN-214
×
Maximum Phase:
1
First Approval:
None
UNII:
94E9UR0RFR
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAK-960
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Serine/threonine-protein kinase PLK1 inhibitor
TAK-960
×
Maximum Phase:
1
First Approval:
None
UNII:
3831VFM1ZB
Molecule Type:
Small molecule
Molecular Formula:
C27H34F3N7O3
Molecular Weight:
561.61
AlogP:
3.55
PSA:
102.93
HBD:
2.0
HBA:
#RotB:
6.0
Source:
NONA-L-ARGININE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
NONA-L-ARGININE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DSTP3086S
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
DSTP3086S
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ARC1905
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
ARC1905
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AV-412
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AV-412
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GDC-0927
1
Unknown
Investigational
Unknown
Unknown
Breast Neoplasms
Unknown
GDC-0927
×
Maximum Phase:
1
First Approval:
None
UNII:
ST9B0EMC0H
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CALANOLIDE A
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
CALANOLIDE A
×
Maximum Phase:
1
First Approval:
None
UNII:
S5A9TQN46W
Molecule Type:
Small molecule
Molecular Formula:
C22H26O5
Molecular Weight:
370.45
AlogP:
4.38
PSA:
68.9
HBD:
1.0
HBA:
#RotB:
2.0
Source:
GS-9901
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular
Unknown
GS-9901
×
Maximum Phase:
1
First Approval:
None
UNII:
U09Q76B8VK
Molecule Type:
Small molecule
Molecular Formula:
C22H17ClFN9O
Molecular Weight:
477.89
AlogP:
2.96
PSA:
161.42
HBD:
3.0
HBA:
#RotB:
5.0
Source:
MLN-591RL
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
MLN-591RL
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IBI-188
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms
Unknown
IBI-188
×
Maximum Phase:
1
First Approval:
None
UNII:
BDN84I1TFE
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
1
2
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Maximum Phase
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Molecular Formula
Molecular Weight
ALogP
PSA