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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
Small Molecules
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
LHC-165
1
Unknown
Investigational
Unknown
Unknown
Neoplasms
Unknown
LHC-165
×
Maximum Phase:
1
First Approval:
None
UNII:
RD02U4QLM1
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ASTX-660
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma
Unknown
ASTX-660
×
Maximum Phase:
1
First Approval:
None
UNII:
2LHZ9ZC3YO
Molecule Type:
Small molecule
Molecular Formula:
C30H42FN5O3
Molecular Weight:
539.7
AlogP:
2.31
PSA:
81.17
HBD:
2.0
HBA:
#RotB:
7.0
Source:
TEBOTELIMAB
1
Antibody
Investigational
Unknown
Unknown
Breast Neoplasms; Carcinoma, Hepatocellular; Endometrial Neoplasms; Stomach Neoplasms; Carcinoma, Squamous Cell
Lymphocyte activation gene 3 protein inhibitor
TEBOTELIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
L62556GPXB
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DOTAMTATE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
DOTAMTATE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
C65H91N17O16PbS2
Molecular Weight:
1637.88
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
BENZOYLPHENYLUREA
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
BENZOYLPHENYLUREA
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C14H12N2O2
Molecular Weight:
240.26
AlogP:
2.41
PSA:
63.4
HBD:
1.0
HBA:
#RotB:
2.0
Source:
RGB-286638
1
Small molecule
Investigational
Unknown
Unknown
Hematologic Neoplasms
Cyclin-dependent kinase 1 inhibitor
RGB-286638
×
Maximum Phase:
1
First Approval:
None
UNII:
1GAJ98SC2X
Molecule Type:
Small molecule
Molecular Formula:
C29H35N7O4
Molecular Weight:
545.64
AlogP:
2.42
PSA:
115.06
HBD:
3.0
HBA:
#RotB:
8.0
Source:
FN-1501
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute
Unknown
FN-1501
×
Maximum Phase:
1
First Approval:
None
UNII:
6MC966B505
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LS 11
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LS 11
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BI 639667
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BI 639667
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C22H18FN5O3S
Molecular Weight:
451.48
AlogP:
2.78
PSA:
106.84
HBD:
1.0
HBA:
#RotB:
5.0
Source:
IMD-0354
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
IMD-0354
×
Maximum Phase:
1
First Approval:
None
UNII:
76145IS906
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GT-0918
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Severe Acute Respiratory Syndrome
Androgen Receptor antagonist
GT-0918
×
Maximum Phase:
1
First Approval:
None
UNII:
QX6O64GP40
Molecule Type:
Small molecule
Molecular Formula:
C24H19F4N5O2S
Molecular Weight:
517.51
AlogP:
5.19
PSA:
86.26
HBD:
0.0
HBA:
#RotB:
6.0
Source:
VANDORTUZUMAB VEDOTIN
1
Antibody
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Metalloreductase STEAP1 binding agent
VANDORTUZUMAB VEDOTIN
×
Maximum Phase:
1
First Approval:
None
UNII:
44OUQ00D1U
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK-3050002
1
Unknown
Investigational
Unknown
Unknown
Colitis, Ulcerative; Immune System Diseases
Unknown
GSK-3050002
×
Maximum Phase:
1
First Approval:
None
UNII:
1PQB4AA2CT
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CYC-065
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms
Unknown
CYC-065
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLAPTESED PEGOL
1
Unknown
Investigational
Unknown
Unknown
Glioblastoma; Pancreatic Neoplasms
Unknown
OLAPTESED PEGOL
×
Maximum Phase:
1
First Approval:
None
UNII:
MTM792B442
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PF-04605412
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Fibronectin receptor alpha inhibitor
PF-04605412
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK-625433
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GSK-625433
×
Maximum Phase:
1
First Approval:
None
UNII:
2YAD6KT0NT
Molecule Type:
Small molecule
Molecular Formula:
C26H32N4O5S
Molecular Weight:
512.63
AlogP:
4.02
PSA:
106.78
HBD:
1.0
HBA:
#RotB:
8.0
Source:
LY-3031207
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LY-3031207
×
Maximum Phase:
1
First Approval:
None
UNII:
NQ7VQ61PBC
Molecule Type:
Small molecule
Molecular Formula:
C16H19ClN4O2
Molecular Weight:
334.81
AlogP:
2.98
PSA:
86.88
HBD:
3.0
HBA:
#RotB:
4.0
Source:
CP-742,033
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CP-742,033
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZADIRACHTA INDICA
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
AZADIRACHTA INDICA
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DSTP3086S
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
DSTP3086S
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AGN-201904
1
Small molecule
Investigational
Unknown
Unknown
Peptic Ulcer
Unknown
AGN-201904
×
Maximum Phase:
1
First Approval:
None
UNII:
G0835O03ZM
Molecule Type:
Small molecule
Molecular Formula:
C25H25N3O8S2
Molecular Weight:
559.62
AlogP:
3.07
PSA:
146.91
HBD:
1.0
HBA:
#RotB:
10.0
Source:
ALVIRCEPT SUDOTOX
1
Protein
Investigational
Unknown
Unknown
HIV Infections
Unknown
ALVIRCEPT SUDOTOX
×
Maximum Phase:
1
First Approval:
None
UNII:
Q67R7N520V
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PI-0824
1
Unknown
Investigational
Unknown
Unknown
Pemphigus
Unknown
PI-0824
×
Maximum Phase:
1
First Approval:
None
UNII:
UG5KU6AQ0Z
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CTT-1057
1
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Unknown
CTT-1057
×
Maximum Phase:
1
First Approval:
None
UNII:
QMH3V8VSPB
Molecule Type:
Small molecule
Molecular Formula:
C28H40FN4O14P
Molecular Weight:
706.61
AlogP:
0.84
PSA:
295.06
HBD:
9.0
HBA:
#RotB:
25.0
Source:
MK-3281
1
Small molecule
Investigational
Unknown
Unknown
Hepatitis C
Unknown
MK-3281
×
Maximum Phase:
1
First Approval:
None
UNII:
3593C180JO
Molecule Type:
Small molecule
Molecular Formula:
C29H37N3O3
Molecular Weight:
475.63
AlogP:
5.31
PSA:
57.94
HBD:
1.0
HBA:
#RotB:
6.0
Source:
GASTRIN
1
Protein
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 1
Unknown
GASTRIN
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Protein
Molecular Formula:
C97H126N20O32S
Molecular Weight:
2116.25
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
LU AF-82422
1
Unknown
Investigational
Unknown
Unknown
Parkinson Disease
Unknown
LU AF-82422
×
Maximum Phase:
1
First Approval:
None
UNII:
52V6AS6U0A
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CAL-263
1
Small molecule
Investigational
Unknown
Unknown
Rhinitis, Allergic, Seasonal
PI3-kinase p110-delta subunit inhibitor
CAL-263
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PALOMID-529
1
Small molecule
Investigational
Unknown
Unknown
Macular Degeneration
Serine/threonine-protein kinase mTOR inhibitor
PALOMID-529
×
Maximum Phase:
1
First Approval:
None
UNII:
XV9409EWG4
Molecule Type:
Small molecule
Molecular Formula:
C24H22O6
Molecular Weight:
406.43
AlogP:
4.6
PSA:
78.13
HBD:
1.0
HBA:
#RotB:
6.0
Source:
LY-3007113
1
Small molecule
Investigational
Unknown
Unknown
Unknown
MAP kinase p38 alpha inhibitor
LY-3007113
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DM-1157
1
Small molecule
Investigational
Unknown
Unknown
Malaria
Unknown
DM-1157
×
Maximum Phase:
1
First Approval:
None
UNII:
6X58GJ0RMS
Molecule Type:
Small molecule
Molecular Formula:
C28H31ClN6
Molecular Weight:
487.05
AlogP:
5.32
PSA:
65.97
HBD:
2.0
HBA:
#RotB:
9.0
Source:
L-FUCOSE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
L-FUCOSE
×
Maximum Phase:
1
First Approval:
None
UNII:
28RYY2IV3F
Molecule Type:
Small molecule
Molecular Formula:
C6H12O5
Molecular Weight:
164.16
AlogP:
-2.19
PSA:
90.15
HBD:
4.0
HBA:
#RotB:
0.0
Source:
PHIP
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
PHIP
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GLPG0259
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GLPG0259
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
1
2
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112
113
114
115
116
117
118
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305
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Compound Name
Maximum Phase
Compound Structure
Smile
Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA