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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
OCTANOIC ACID
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Essential Tremor; Gallbladder Neoplasms; Leukemia, Myeloid, Acute; Small Cell Lung Carcinoma; Myelodysplastic Syndromes; Sarcoma, Myeloid
Unknown
OCTANOIC ACID
×
Maximum Phase:
1
First Approval:
None
UNII:
OBL58JN025
Molecule Type:
Small molecule
Molecular Formula:
C8H16O2
Molecular Weight:
144.21
AlogP:
2.43
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
6.0
Source:
RG7185
1
Small molecule
Investigational
Unknown
Unknown
Unknown
G protein-coupled receptor 44 antagonist
RG7185
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SCIO-323
1
Small molecule
Investigational
Unknown
Unknown
Unknown
MAP kinase p38 alpha inhibitor
SCIO-323
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C27H30FN3O4
Molecular Weight:
479.55
AlogP:
3.69
PSA:
71.85
HBD:
0.0
HBA:
#RotB:
6.0
Source:
PEGLOXENATIDE
1
Protein
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
PEGLOXENATIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RGB-286638
1
Small molecule
Investigational
Unknown
Unknown
Hematologic Neoplasms
Cyclin-dependent kinase 1 inhibitor
RGB-286638
×
Maximum Phase:
1
First Approval:
None
UNII:
1GAJ98SC2X
Molecule Type:
Small molecule
Molecular Formula:
C29H35N7O4
Molecular Weight:
545.64
AlogP:
2.42
PSA:
115.06
HBD:
3.0
HBA:
#RotB:
8.0
Source:
GARIVULIMAB
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Unknown
GARIVULIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLAPTESED PEGOL
1
Unknown
Investigational
Unknown
Unknown
Glioblastoma; Pancreatic Neoplasms
Unknown
OLAPTESED PEGOL
×
Maximum Phase:
1
First Approval:
None
UNII:
MTM792B442
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-986120
1
Unknown
Investigational
Unknown
Unknown
Thrombosis
Unknown
BMS-986120
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
KPT-9274
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin
Unknown
KPT-9274
×
Maximum Phase:
1
First Approval:
None
UNII:
9T56TV18X7
Molecule Type:
Small molecule
Molecular Formula:
C35H29F3N4O3
Molecular Weight:
610.64
AlogP:
7.08
PSA:
101.46
HBD:
2.0
HBA:
#RotB:
7.0
Source:
PRT-2607
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Tyrosine-protein kinase SYK inhibitor
PRT-2607
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AVID-200
1
Unknown
Investigational
Unknown
Unknown
Neoplasms; Scleroderma, Diffuse
Unknown
AVID-200
×
Maximum Phase:
1
First Approval:
None
UNII:
6EX05GL2VK
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IMC-3C5
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Vascular endothelial growth factor receptor 3 inhibitor
IMC-3C5
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
METHYLSELENOCYSTEINE
1
Small molecule
Investigational
Unknown
Unknown
Adenoma; Lymphoma; Prostatic Neoplasms
Unknown
METHYLSELENOCYSTEINE
×
Maximum Phase:
1
First Approval:
None
UNII:
TWK220499Z
Molecule Type:
Small molecule
Molecular Formula:
C4H9NO2Se
Molecular Weight:
182.08
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
AZADIRACHTA INDICA
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
AZADIRACHTA INDICA
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK-625433
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GSK-625433
×
Maximum Phase:
1
First Approval:
None
UNII:
2YAD6KT0NT
Molecule Type:
Small molecule
Molecular Formula:
C26H32N4O5S
Molecular Weight:
512.63
AlogP:
4.02
PSA:
106.78
HBD:
1.0
HBA:
#RotB:
8.0
Source:
DS-8273A
1
Unknown
Investigational
Unknown
Unknown
Colorectal Neoplasms; Lymphoma; Melanoma
Unknown
DS-8273A
×
Maximum Phase:
1
First Approval:
None
UNII:
G674PEN33T
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CP-742,033
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CP-742,033
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MMI-0100
1
Protein
Investigational
Unknown
Unknown
Inflammation
Unknown
MMI-0100
×
Maximum Phase:
1
First Approval:
None
UNII:
6VP6PBL1ZH
Molecule Type:
Protein
Molecular Formula:
C98H171N37O26
Molecular Weight:
2283.68
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
AGN-201904
1
Small molecule
Investigational
Unknown
Unknown
Peptic Ulcer
Unknown
AGN-201904
×
Maximum Phase:
1
First Approval:
None
UNII:
G0835O03ZM
Molecule Type:
Small molecule
Molecular Formula:
C25H25N3O8S2
Molecular Weight:
559.62
AlogP:
3.07
PSA:
146.91
HBD:
1.0
HBA:
#RotB:
10.0
Source:
ASP-4058
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ASP-4058
×
Maximum Phase:
1
First Approval:
None
UNII:
01J7526K2Q
Molecule Type:
Small molecule
Molecular Formula:
C19H12F6N4O2
Molecular Weight:
442.32
AlogP:
5.63
PSA:
76.83
HBD:
1.0
HBA:
#RotB:
4.0
Source:
RG-7603
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin
Serine/threonine-protein kinase mTOR inhibitor
RG-7603
×
Maximum Phase:
1
First Approval:
None
UNII:
579255I6O9
Molecule Type:
Small molecule
Molecular Formula:
C24H32N6O3
Molecular Weight:
452.56
AlogP:
2.27
PSA:
91.85
HBD:
2.0
HBA:
#RotB:
5.0
Source:
SYM-023
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
SYM-023
×
Maximum Phase:
1
First Approval:
None
UNII:
9GEU9XHE20
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TRV-120027
1
Protein
Investigational
Unknown
Unknown
Heart Failure; Severe Acute Respiratory Syndrome
Unknown
TRV-120027
×
Maximum Phase:
1
First Approval:
None
UNII:
J1J4P3PQZD
Molecule Type:
Protein
Molecular Formula:
C43H67N13O10
Molecular Weight:
926.09
AlogP:
-1.91
PSA:
355.05
HBD:
13.0
HBA:
#RotB:
26.0
Source:
AQ-13
1
Unknown
Investigational
Unknown
Unknown
Malaria
Unknown
AQ-13
×
Maximum Phase:
1
First Approval:
None
UNII:
PKT9732S5K
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NEMIRALISIB
1
Small molecule
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
PI3-kinase p110-delta subunit inhibitor
NEMIRALISIB
×
Maximum Phase:
1
First Approval:
None
UNII:
OEP8JJ3OZR
Molecule Type:
Small molecule
Molecular Formula:
C26H28N6O
Molecular Weight:
440.55
AlogP:
4.89
PSA:
76.98
HBD:
2.0
HBA:
#RotB:
5.0
Source:
LS 11
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LS 11
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAFETINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
TAFETINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
H4X2M2NN5N
Molecule Type:
Small molecule
Molecular Formula:
C24H29FN4O2
Molecular Weight:
424.52
AlogP:
3.73
PSA:
77.23
HBD:
3.0
HBA:
#RotB:
6.0
Source:
LHC-165
1
Unknown
Investigational
Unknown
Unknown
Neoplasms
Unknown
LHC-165
×
Maximum Phase:
1
First Approval:
None
UNII:
RD02U4QLM1
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DSTP3086S
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
DSTP3086S
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CYC-065
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms
Unknown
CYC-065
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-4785
1
Unknown
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Unknown
AZD-4785
×
Maximum Phase:
1
First Approval:
None
UNII:
D43WWD6RDZ
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CEP-37440
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
ALK tyrosine kinase receptor inhibitor
CEP-37440
×
Maximum Phase:
1
First Approval:
None
UNII:
O3MNS8782H
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NONA-L-ARGININE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
NONA-L-ARGININE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IMGN-388
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Vitronectin receptor alpha binding agent
IMGN-388
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
Y-39983
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Rho-associated protein kinase inhibitor
Y-39983
×
Maximum Phase:
1
First Approval:
None
UNII:
00ALI1GAY2
Molecule Type:
Small molecule
Molecular Formula:
C16H16N4O
Molecular Weight:
280.33
AlogP:
2.83
PSA:
83.8
HBD:
3.0
HBA:
#RotB:
3.0
Source:
1
2
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119
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PSA