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Therapeutic Area
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CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
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Primary Target
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Level 2
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Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
HX-1171
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HX-1171
×
Maximum Phase:
1
First Approval:
None
UNII:
70BK60I8RP
Molecule Type:
Small molecule
Molecular Formula:
C15H24O2
Molecular Weight:
236.35
AlogP:
4.28
PSA:
29.46
HBD:
1.0
HBA:
#RotB:
6.0
Source:
AZD-4785
1
Unknown
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Unknown
AZD-4785
×
Maximum Phase:
1
First Approval:
None
UNII:
D43WWD6RDZ
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
EPITINIB
1
Small molecule
Investigational
Unknown
Unknown
Glioblastoma; Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
EPITINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
WZ97ZE4UUG
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LUMILIXIMAB
1
Antibody
Investigational
Unknown
Unknown
Leukemia; Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell
Immunoglobulin epsilon Fc receptor antagonist
LUMILIXIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
8Z13S29R5A
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IMGN-388
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Vitronectin receptor alpha binding agent
IMGN-388
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
Y-39983
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Rho-associated protein kinase inhibitor
Y-39983
×
Maximum Phase:
1
First Approval:
None
UNII:
00ALI1GAY2
Molecule Type:
Small molecule
Molecular Formula:
C16H16N4O
Molecular Weight:
280.33
AlogP:
2.83
PSA:
83.8
HBD:
3.0
HBA:
#RotB:
3.0
Source:
FAZ-053
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
FAZ-053
×
Maximum Phase:
1
First Approval:
None
UNII:
V6W1OW12H2
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-984923
1
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Unknown
BMS-984923
×
Maximum Phase:
1
First Approval:
None
UNII:
3I1803DK5Z
Molecule Type:
Small molecule
Molecular Formula:
C22H15ClN2O2
Molecular Weight:
374.83
AlogP:
4.66
PSA:
51.22
HBD:
1.0
HBA:
#RotB:
2.0
Source:
CP-742,033
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CP-742,033
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CYC-065
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms
Unknown
CYC-065
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RG-7444
1
Antibody
Investigational
Unknown
Unknown
Unknown
Fibroblast growth factor receptor 3 inhibitor
RG-7444
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CENICRIVIROC MESYLATE
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
CENICRIVIROC MESYLATE
×
Maximum Phase:
1
First Approval:
None
UNII:
R96TV84T21
Molecule Type:
Small molecule
Molecular Formula:
C42H56N4O7S2
Molecular Weight:
793.06
AlogP:
8.74
PSA:
85.69
HBD:
1.0
HBA:
#RotB:
17.0
Source:
RG-7376
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Serine/threonine-protein kinase RAF inhibitor
RG-7376
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GUSUIBU
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
GUSUIBU
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLAPTESED PEGOL
1
Unknown
Investigational
Unknown
Unknown
Glioblastoma; Pancreatic Neoplasms
Unknown
OLAPTESED PEGOL
×
Maximum Phase:
1
First Approval:
None
UNII:
MTM792B442
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SBC-103
1
Enzyme
Investigational
Unknown
Unknown
Unknown
Unknown
SBC-103
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PEXMETINIB
1
Small molecule
Investigational
Unknown
Unknown
Myelodysplastic Syndromes
MAP kinase p38 alpha inhibitor
PEXMETINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
3750D0U8B5
Molecule Type:
Small molecule
Molecular Formula:
C31H33FN6O3
Molecular Weight:
556.64
AlogP:
6.07
PSA:
106.23
HBD:
3.0
HBA:
#RotB:
8.0
Source:
AGN-201904
1
Small molecule
Investigational
Unknown
Unknown
Peptic Ulcer
Unknown
AGN-201904
×
Maximum Phase:
1
First Approval:
None
UNII:
G0835O03ZM
Molecule Type:
Small molecule
Molecular Formula:
C25H25N3O8S2
Molecular Weight:
559.62
AlogP:
3.07
PSA:
146.91
HBD:
1.0
HBA:
#RotB:
10.0
Source:
GSK-690693
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
cAMP-dependent protein kinase (PKA) inhibitor
GSK-690693
×
Maximum Phase:
1
First Approval:
None
UNII:
GWH480321B
Molecule Type:
Small molecule
Molecular Formula:
C21H27N7O3
Molecular Weight:
425.49
AlogP:
1.58
PSA:
137.14
HBD:
3.0
HBA:
#RotB:
5.0
Source:
IGN-523
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute
Unknown
IGN-523
×
Maximum Phase:
1
First Approval:
None
UNII:
7OI79TB6KN
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DSTP3086S
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
DSTP3086S
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TRV-120027
1
Protein
Investigational
Unknown
Unknown
Heart Failure; Severe Acute Respiratory Syndrome
Unknown
TRV-120027
×
Maximum Phase:
1
First Approval:
None
UNII:
J1J4P3PQZD
Molecule Type:
Protein
Molecular Formula:
C43H67N13O10
Molecular Weight:
926.09
AlogP:
-1.91
PSA:
355.05
HBD:
13.0
HBA:
#RotB:
26.0
Source:
FGF-1
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
FGF-1
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK2879552
1
Small molecule
Investigational
Unknown
Unknown
Leukemia; Myelodysplastic Syndromes; Small Cell Lung Carcinoma
Unknown
GSK2879552
×
Maximum Phase:
1
First Approval:
None
UNII:
GT77Z6Y09Z
Molecule Type:
Small molecule
Molecular Formula:
C23H28N2O2
Molecular Weight:
364.49
AlogP:
3.74
PSA:
52.57
HBD:
2.0
HBA:
#RotB:
7.0
Source:
ASP-4058
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ASP-4058
×
Maximum Phase:
1
First Approval:
None
UNII:
01J7526K2Q
Molecule Type:
Small molecule
Molecular Formula:
C19H12F6N4O2
Molecular Weight:
442.32
AlogP:
5.63
PSA:
76.83
HBD:
1.0
HBA:
#RotB:
4.0
Source:
NONA-L-ARGININE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
NONA-L-ARGININE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TEMANOGREL
1
Small molecule
Investigational
Unknown
Unknown
Acute Coronary Syndrome
Serotonin 2a (5-HT2a) receptor inverse agonist
TEMANOGREL
×
Maximum Phase:
1
First Approval:
None
UNII:
F42Z27575A
Molecule Type:
Small molecule
Molecular Formula:
C24H28N4O4
Molecular Weight:
436.51
AlogP:
3.06
PSA:
77.85
HBD:
1.0
HBA:
#RotB:
8.0
Source:
SAR-260301
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
PI3-kinase p110-beta subunit inhibitor
SAR-260301
×
Maximum Phase:
1
First Approval:
None
UNII:
33639WNC7Q
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MEDI4276
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
MEDI4276
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
S-222611
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Epidermal growth factor receptor erbB1 inhibitor
S-222611
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RG-7603
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin
Serine/threonine-protein kinase mTOR inhibitor
RG-7603
×
Maximum Phase:
1
First Approval:
None
UNII:
579255I6O9
Molecule Type:
Small molecule
Molecular Formula:
C24H32N6O3
Molecular Weight:
452.56
AlogP:
2.27
PSA:
91.85
HBD:
2.0
HBA:
#RotB:
5.0
Source:
GSK-625433
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GSK-625433
×
Maximum Phase:
1
First Approval:
None
UNII:
2YAD6KT0NT
Molecule Type:
Small molecule
Molecular Formula:
C26H32N4O5S
Molecular Weight:
512.63
AlogP:
4.02
PSA:
106.78
HBD:
1.0
HBA:
#RotB:
8.0
Source:
HMN-214
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Serine/threonine-protein kinase PLK1 inhibitor
HMN-214
×
Maximum Phase:
1
First Approval:
None
UNII:
94E9UR0RFR
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ASTX-660
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma
Unknown
ASTX-660
×
Maximum Phase:
1
First Approval:
None
UNII:
2LHZ9ZC3YO
Molecule Type:
Small molecule
Molecular Formula:
C30H42FN5O3
Molecular Weight:
539.7
AlogP:
2.31
PSA:
81.17
HBD:
2.0
HBA:
#RotB:
7.0
Source:
FLUOCINOLONE
1
Small molecule
Investigational
Unknown
Unknown
Wet Macular Degeneration
Unknown
FLUOCINOLONE
×
Maximum Phase:
1
First Approval:
None
UNII:
CT1IX58L9S
Molecule Type:
Small molecule
Molecular Formula:
C21H26F2O6
Molecular Weight:
412.43
AlogP:
0.57
PSA:
115.06
HBD:
4.0
HBA:
#RotB:
2.0
Source:
1
2
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Maximum Phase
Compound Structure
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Inchi
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Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA