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Total: 10647
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Alzheimer Disease; Urinary Bladder Neoplasms; Astrocytoma; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Medulloblastoma; Nasopharyngeal Neoplasms; Neoplasms; Ovarian Neoplasms; Sarcoma; Shock; Wounds and Injuries; Alopecia; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glioma; Head and Neck Neoplasms; HIV Infections; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Melanoma; Muscular Atrophy, Spinal; Myelodysplastic Syndromes; Neuralgia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retinitis Pigmentosa; Small Cell Lung Carcinoma; Supranuclear Palsy, Progressive; Thyroid Neoplasms; Anxiety; Dementia; Depressive Disorder; Paraparesis, Tropical Spastic; Schizophrenia; Status Epilepticus; Anorexia; Bipolar Disorder; Epilepsy; Epilepsy, Absence; Epilepsy, Complex Partial; Migraine Disorders; Mitochondrial Diseases; Seizures; Vomiting
Succinate semialdehyde dehydrogenase inhibitor
Small molecule
Approved
OTHER
OPHTHALMIC; ORAL
Optic Neuropathy, Ischemic; Corneal Edema; Hemangioma; Hypertension, Portal; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension
Beta-1 adrenergic receptor antagonist
Small molecule
Approved
OTHER
INJECTION
Rhabdomyosarcoma; Carcinoma, Basal Cell; Carcinoma, Endometrioid; Carcinoma, Merkel Cell; Cystadenoma, Serous; Digestive System Neoplasms; Genital Neoplasms, Female; Kidney Diseases; Klatskin Tumor; Liver Diseases; Xerostomia; Carcinoid Tumor; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Digestive System Diseases; Ganglioneuroblastoma; Gastrointestinal Stromal Tumors; Glioma; Granuloma, Lethal Midline; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, AIDS-Related; Lymphoma, Follicular; Lymphoma, Large-Cell, Anaplastic; Myelodysplastic Syndromes; Nausea; Neoplasm Metastasis; Penile Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Thymoma; Thyroid Neoplasms; Tongue Neoplasms; Triple Negative Breast Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Adrenal Cortex Neoplasms; Anemia; Anus Neoplasms; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Cholangiocarcinoma; Choriocarcinoma; Choroid Plexus Neoplasms; Colorectal Neoplasms; Endodermal Sinus Tumor; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Gestational Trophoblastic Disease; Head and Neck Neoplasms; Hepatoblastoma; Hodgkin Disease; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Laryngeal Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Malaria; Mediastinal Neoplasms; Medulloblastoma; Melanoma; Mesothelioma; Mouth Neoplasms; Mucositis; Multiple Myeloma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neuroectodermal Tumors, Primitive; Oropharyngeal Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Pleural Effusion; Postoperative Nausea and Vomiting; Retinoblastoma; Sarcoma; Seminoma; Sex Cord-Gonadal Stromal Tumors; Skin Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Stomatitis; Teratoma; Testicular Neoplasms; Thymus Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Vulvar Neoplasms; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
INTRAVESICAL
HIV Infections; Melanoma; Neoplasms; Osteoarthritis; Contracture; Cystitis, Interstitial; Reflex, Abnormal; Urinary Bladder, Overactive; Urinary Incontinence, Urge; Arthralgia; Cystitis; Infections; Myalgia
Unknown
Small molecule
Approved
Unknown
Unknown
Dermatitis, Atopic; HIV Infections; Malaria; Neoplasms; Psoriasis; Arrhythmias, Cardiac; beta-Thalassemia; Death, Sudden, Cardiac; Heart Diseases; Hypotension, Orthostatic; Obesity; Prader-Willi Syndrome; Premature Birth; Tachycardia, Ventricular; Ventricular Fibrillation; Atherosclerosis; Atrial Fibrillation; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 2; Heart Failure; Hypercholesterolemia; Hypertension; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; ST Elevation Myocardial Infarction; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Protein
Approved
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant; Hypertension; Breast Neoplasms; Leptospirosis; Urinary Bladder, Overactive; Diabetes Insipidus; Enuresis; Renal Colic
Unknown
Small molecule
Approved
OTHER
INJECTION
Unknown
Diagnostic agent
Small molecule
Approved
OTHER
ORAL
Substance-Related Disorders; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
Unknown
Unknown
Tuberculosis, Pulmonary; Bacterial Infections; Infections; Pharyngitis
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Cyclooxygenase inhibitor
Small molecule
Approved
OTHER
OPHTHALMIC
Mycoses; Keratitis; Eye Infections; Infections
Ergosterol sequestering agent
Protein
Approved
MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY
INJECTION; NASAL
Menopause; Osteoporosis; Hypercalcemia; Osteitis Deformans; Osteoporosis, Postmenopausal
Calcitonin receptor agonist
Small molecule
Approved
Unknown
Unknown
Anxiety; Pain
Unknown
Small molecule
Approved
Unknown
Unknown
Anorexia Nervosa; Adenomyosis; Alzheimer Disease; Diabetes Mellitus, Type 1; Intellectual Disability; Obesity; Ovarian Hyperstimulation Syndrome; Parkinson Disease
Unknown
Small molecule
Approved
Unknown
Unknown
Acute Lung Injury; Brain Injuries; Shock; Shock, Septic; Heart Failure; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Dry Eye Syndromes; Eye Manifestations; Nasal Obstruction
Unknown
Small molecule
Approved
Unknown
Unknown
Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Anemia, Refractory; Leukemia, Myeloid; Myelodysplastic Syndromes; Hepatitis B, Chronic; Leukemia; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency, Chronic; Sarcoma, Kaposi; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Neoplasms
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Lung Diseases, Obstructive
Unknown
Small molecule
Approved
OTHER
ORAL
Psychotic Disorders; Hypertension; Pheochromocytoma
Tyrosine 3-hydroxylase inhibitor
Small molecule
Approved
OTHER
ORAL; TOPICAL
Carcinoma, Non-Small-Cell Lung; Pemphigoid, Benign Mucous Membrane; Pemphigus; Pulmonary Fibrosis; Rosacea; Sarcoidosis; Stroke; Fever; HIV Infections; Malaria; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Severe Acute Respiratory Syndrome; Acne Vulgaris; Dermatitis Herpetiformis; Leprosy
Dihydropteroate synthase 1 inhibitor
Small molecule
Unknown
Unknown
Unknown
Alzheimer Disease; Dementia; Depressive Disorder, Major; Phobia, Social; Renal Colic; Amyotrophic Lateral Sclerosis; Bipolar Disorder; Depressive Disorder; Pain; Motion Sickness; Nausea; Postoperative Nausea and Vomiting
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
OTHER
TOPICAL
Unknown
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections; Bronchitis, Chronic; Infections; Otitis Media; Pharyngitis; Pneumonia; Sprains and Strains; Tonsillitis; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
Unknown
Unknown
Rheumatic Diseases
Cyclooxygenase inhibitor
Small molecule
Approved
Unknown
Unknown
Cardiovascular Diseases
Unknown
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial penicillin-binding protein inhibitor
Protein
Approved
OTHER
INJECTION
Unknown
Insulin receptor agonist
Small molecule
Approved
Unknown
Unknown
Hypotension, Orthostatic; Orthostatic Intolerance; Gastrointestinal Hemorrhage; Hyperemesis Gravidarum; Hypoglycemia; Intestinal Obstruction; Myelodysplastic Syndromes; Pain; Wounds and Injuries; Gastroenteritis; Gastroparesis; Gastroschisis; Headache; HIV Infections; Migraine Disorders; Nausea; Neoplasms; Sepsis; Vomiting; Digestive System Diseases
Unknown
Protein
Approved
OTHER
INJECTION
Unknown
Insulin receptor agonist
Small molecule
Approved
OTHER
INHALATION
Heart Diseases; Opioid-Related Disorders; Hernia, Inguinal; Respiratory Insufficiency; Severe Acute Respiratory Syndrome
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Anxiety; Dementia; Schizophrenia; Depressive Disorder
Unknown