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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
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Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
BI113823
1
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis
Bradykinin B1 receptor antagonist
BI113823
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
REGN4659
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
REGN4659
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HU8F4
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
HU8F4
×
Maximum Phase:
1
First Approval:
None
UNII:
NL06848HBQ
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CALMANGAFODIPIR
1
Unknown
Investigational
Unknown
Unknown
Peripheral Nervous System Diseases
Unknown
CALMANGAFODIPIR
×
Maximum Phase:
1
First Approval:
None
UNII:
N0JZU0WGU5
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PEGTIBATINASE
1
Enzyme
Investigational
Unknown
Unknown
Homocystinuria
Unknown
PEGTIBATINASE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BALAFILCON A
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BALAFILCON A
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-794833
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Hepatocyte growth factor receptor inhibitor
BMS-794833
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LY-3200882
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
LY-3200882
×
Maximum Phase:
1
First Approval:
None
UNII:
19HY34R6UN
Molecule Type:
Small molecule
Molecular Formula:
C24H29N5O3
Molecular Weight:
435.53
AlogP:
4.67
PSA:
94.32
HBD:
2.0
HBA:
#RotB:
7.0
Source:
SIMOTAXEL
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
SIMOTAXEL
×
Maximum Phase:
1
First Approval:
None
UNII:
E1M30YOE59
Molecule Type:
Small molecule
Molecular Formula:
C46H57NO15S
Molecular Weight:
896.02
AlogP:
4.67
PSA:
230.52
HBD:
4.0
HBA:
#RotB:
11.0
Source:
CO-ZIDOCAPT
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CO-ZIDOCAPT
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C16H23ClN4O7S3
Molecular Weight:
515.04
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
GSK-369796
1
Small molecule
Investigational
Unknown
Unknown
Malaria
Unknown
GSK-369796
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C20H22ClN3O
Molecular Weight:
355.87
AlogP:
5.23
PSA:
57.18
HBD:
3.0
HBA:
#RotB:
4.0
Source:
DELANZOMIB
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin; Multiple Myeloma
Unknown
DELANZOMIB
×
Maximum Phase:
1
First Approval:
None
UNII:
6IF28942WO
Molecule Type:
Small molecule
Molecular Formula:
C21H28BN3O5
Molecular Weight:
413.28
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
HUMIK-BETA-1
1
Antibody
Investigational
Unknown
Unknown
Celiac Disease; HTLV-I Infections; Leukemia, Large Granular Lymphocytic
Interleukin-2 receptor beta chain inhibitor
HUMIK-BETA-1
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CLX-0921
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Peroxisome proliferator-activated receptor gamma agonist
CLX-0921
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TIBULIZUMAB
1
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Sjogren's Syndrome
Interleukin 17A inhibitor
TIBULIZUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
42HQ15W1ZF
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MONO-DGA-RFB4
1
Antibody
Investigational
Unknown
Unknown
Lymphoma
CD22 binding agent
MONO-DGA-RFB4
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PKI-166
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Epidermal growth factor receptor erbB1 inhibitor
PKI-166
×
Maximum Phase:
1
First Approval:
None
UNII:
9RIE5HW38P
Molecule Type:
Small molecule
Molecular Formula:
C20H18N4O
Molecular Weight:
330.39
AlogP:
4.5
PSA:
73.83
HBD:
3.0
HBA:
#RotB:
4.0
Source:
PTI-6D2
1
Antibody
Investigational
Unknown
Unknown
Melanoma
Melanin binding agent
PTI-6D2
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ASP-1951
1
Unknown
Investigational
Unknown
Unknown
Neoplasms
Unknown
ASP-1951
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MITAZALIMAB
1
Antibody
Investigational
Unknown
Unknown
Carcinoma, Pancreatic Ductal; Neoplasms
Unknown
MITAZALIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
Q9J81E7VFM
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INCAGN-02385
1
Unknown
Investigational
Unknown
Unknown
Melanoma
Unknown
INCAGN-02385
×
Maximum Phase:
1
First Approval:
None
UNII:
Z0A08C63DF
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
E7107
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
E7107
×
Maximum Phase:
1
First Approval:
None
UNII:
R60DZX1E2N
Molecule Type:
Small molecule
Molecular Formula:
C40H66N2O9
Molecular Weight:
718.97
AlogP:
5.05
PSA:
152.53
HBD:
4.0
HBA:
#RotB:
10.0
Source:
BTA-9881
1
Small molecule
Investigational
Unknown
Unknown
Respiratory Syncytial Virus Infections
Unknown
BTA-9881
×
Maximum Phase:
1
First Approval:
None
UNII:
9VR1J6U4XG
Molecule Type:
Small molecule
Molecular Formula:
C21H15ClN4O2
Molecular Weight:
390.83
AlogP:
2.94
PSA:
66.4
HBD:
0.0
HBA:
#RotB:
2.0
Source:
UNESBULIN
1
Small molecule
Investigational
Unknown
Unknown
Diffuse Intrinsic Pontine Glioma; Leiomyosarcoma; Neoplasms; Ovarian Neoplasms
Unknown
UNESBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
Z4HZ70S62Q
Molecule Type:
Small molecule
Molecular Formula:
C19H13F5N6
Molecular Weight:
420.35
AlogP:
4.75
PSA:
81.65
HBD:
2.0
HBA:
#RotB:
3.0
Source:
TAS-115
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Hepatocyte growth factor receptor inhibitor
TAS-115
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SALVINORIN A
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SALVINORIN A
×
Maximum Phase:
1
First Approval:
None
UNII:
T56W91NG6J
Molecule Type:
Small molecule
Molecular Formula:
C23H28O8
Molecular Weight:
432.47
AlogP:
3.0
PSA:
109.11
HBD:
0.0
HBA:
#RotB:
3.0
Source:
PHA-793887
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Cyclin-dependent kinase inhibitor
PHA-793887
×
Maximum Phase:
1
First Approval:
None
UNII:
MKS45S912B
Molecule Type:
Small molecule
Molecular Formula:
C19H31N5O2
Molecular Weight:
361.49
AlogP:
2.31
PSA:
81.33
HBD:
2.0
HBA:
#RotB:
4.0
Source:
ACT-462206
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ACT-462206
×
Maximum Phase:
1
First Approval:
None
UNII:
64ONO62P28
Molecule Type:
Small molecule
Molecular Formula:
C20H24N2O4S
Molecular Weight:
388.49
AlogP:
3.1
PSA:
75.71
HBD:
1.0
HBA:
#RotB:
5.0
Source:
GDC-0927
1
Unknown
Investigational
Unknown
Unknown
Breast Neoplasms
Unknown
GDC-0927
×
Maximum Phase:
1
First Approval:
None
UNII:
ST9B0EMC0H
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-7451
1
Small molecule
Investigational
Unknown
Unknown
Glioblastoma
Nerve growth factor receptor Trk-A inhibitor
AZD-7451
×
Maximum Phase:
1
First Approval:
None
UNII:
VNM956Y27V
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FOSIFLOXURIDINE NAFALBENAMIDE
1
Small molecule
Investigational
Unknown
Unknown
Colorectal Neoplasms; Neoplasms
Unknown
FOSIFLOXURIDINE NAFALBENAMIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
4YO6QT3SZ9
Molecule Type:
Small molecule
Molecular Formula:
C29H29FN3O9P
Molecular Weight:
613.54
AlogP:
3.4
PSA:
158.18
HBD:
3.0
HBA:
#RotB:
11.0
Source:
F105
1
Antibody
Investigational
Unknown
Unknown
HIV Infections
Envelope polyprotein GP160 inhibitor
F105
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
COM-701
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
COM-701
×
Maximum Phase:
1
First Approval:
None
UNII:
IAY02XUV7L
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TALETRECTINIB ADIPATE
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
TALETRECTINIB ADIPATE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C29H34FN5O5
Molecular Weight:
551.62
AlogP:
4.43
PSA:
77.47
HBD:
2.0
HBA:
#RotB:
7.0
Source:
GAMMA-AMINOBUTYRIC ACID
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 1; Epilepsy
Unknown
GAMMA-AMINOBUTYRIC ACID
×
Maximum Phase:
1
First Approval:
None
UNII:
2ACZ6IPC6I
Molecule Type:
Small molecule
Molecular Formula:
C4H9NO2
Molecular Weight:
103.12
AlogP:
-0.19
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
3.0
Source:
1
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Compound Name
Maximum Phase
Compound Structure
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Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA