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EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
Small Molecules
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
APX-3330
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
DNA-(apurinic or apyrimidinic site) lyase inhibitor
APX-3330
×
Maximum Phase:
2
First Approval:
None
UNII:
11267UI968
Molecule Type:
Small molecule
Molecular Formula:
C21H30O6
Molecular Weight:
378.47
AlogP:
4.11
PSA:
89.9
HBD:
1.0
HBA:
#RotB:
12.0
Source:
AZD-3759
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
AZD-3759
×
Maximum Phase:
2
First Approval:
None
UNII:
67SX9H68W2
Molecule Type:
Small molecule
Molecular Formula:
C22H23ClFN5O3
Molecular Weight:
459.91
AlogP:
4.31
PSA:
79.82
HBD:
1.0
HBA:
#RotB:
4.0
Source:
PTEROSTILBENE
2
Small molecule
Investigational
Unknown
Unknown
Acute Kidney Injury; Endometrial Hyperplasia; Endometrial Neoplasms
Unknown
PTEROSTILBENE
×
Maximum Phase:
2
First Approval:
None
UNII:
26R60S6A5I
Molecule Type:
Small molecule
Molecular Formula:
C16H16O3
Molecular Weight:
256.3
AlogP:
3.58
PSA:
38.69
HBD:
1.0
HBA:
#RotB:
4.0
Source:
MIRAMISTIN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MIRAMISTIN
×
Maximum Phase:
2
First Approval:
None
UNII:
QL5J8F55LH
Molecule Type:
Small molecule
Molecular Formula:
C26H47ClN2O
Molecular Weight:
439.13
AlogP:
6.47
PSA:
29.1
HBD:
1.0
HBA:
#RotB:
18.0
Source:
MIBAMPATOR
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Glutamate receptor ionotropic AMPA positive allosteric modulator
MIBAMPATOR
×
Maximum Phase:
2
First Approval:
None
UNII:
A9V5BW73UU
Molecule Type:
Small molecule
Molecular Formula:
C21H30N2O4S2
Molecular Weight:
438.62
AlogP:
2.88
PSA:
92.34
HBD:
2.0
HBA:
#RotB:
10.0
Source:
JNJ-17166864
2
Small molecule
Investigational
Unknown
Unknown
Rhinitis, Allergic, Seasonal
Unknown
JNJ-17166864
×
Maximum Phase:
2
First Approval:
None
UNII:
VF9KM790TY
Molecule Type:
Small molecule
Molecular Formula:
C21H25Cl2N2O2+
Molecular Weight:
408.35
AlogP:
5.0
PSA:
38.33
HBD:
1.0
HBA:
#RotB:
5.0
Source:
PICEID
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PICEID
×
Maximum Phase:
2
First Approval:
None
UNII:
XM261C37CQ
Molecule Type:
Small molecule
Molecular Formula:
C20H22O8
Molecular Weight:
390.39
AlogP:
0.45
PSA:
139.84
HBD:
6.0
HBA:
#RotB:
5.0
Source:
VERINURAD
2
Small molecule
Investigational
Unknown
Unknown
Gout; Heart Failure; Hyperuricemia; Renal Insufficiency, Chronic
Solute carrier family 22 member 12 inhibitor
VERINURAD
×
Maximum Phase:
2
First Approval:
None
UNII:
12WJ62D047
Molecule Type:
Small molecule
Molecular Formula:
C20H16N2O2S
Molecular Weight:
348.43
AlogP:
4.73
PSA:
73.98
HBD:
1.0
HBA:
#RotB:
4.0
Source:
VIPIVOTIDE TETRAXETAN GALLIUM GA-68
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Unknown
VIPIVOTIDE TETRAXETAN GALLIUM GA-68
×
Maximum Phase:
2
First Approval:
None
UNII:
7P5C02S4X8
Molecule Type:
Small molecule
Molecular Formula:
C49H68GaN9O16
Molecular Weight:
1107.06
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
POLYDEXTROSE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
POLYDEXTROSE
×
Maximum Phase:
2
First Approval:
None
UNII:
VH2XOU12IE
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NM404
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NM404
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
WNT-974
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Squamous Cell
Probable protein-cysteine N-palmitoyltransferase porcupine inhibitor
WNT-974
×
Maximum Phase:
2
First Approval:
None
UNII:
U27F40013Q
Molecule Type:
Small molecule
Molecular Formula:
C23H20N6O
Molecular Weight:
396.45
AlogP:
3.79
PSA:
93.55
HBD:
1.0
HBA:
#RotB:
5.0
Source:
LY-2090314
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Pancreatic Neoplasms; Leukemia
Glycogen synthase kinase-3 alpha inhibitor
LY-2090314
×
Maximum Phase:
2
First Approval:
None
UNII:
822M3GYM67
Molecule Type:
Small molecule
Molecular Formula:
C28H25FN6O3
Molecular Weight:
512.55
AlogP:
3.42
PSA:
91.95
HBD:
1.0
HBA:
#RotB:
2.0
Source:
JNJ-41443532
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
C-C chemokine receptor type 2 antagonist
JNJ-41443532
×
Maximum Phase:
2
First Approval:
None
UNII:
0OJB0LES1A
Molecule Type:
Small molecule
Molecular Formula:
C22H25F3N4O3S
Molecular Weight:
482.53
AlogP:
2.52
PSA:
94.56
HBD:
3.0
HBA:
#RotB:
6.0
Source:
PF-00489791
2
Small molecule
Investigational
Unknown
Unknown
Diabetic Nephropathies; Hypertension; Hypertension, Pulmonary; Raynaud Disease
Phosphodiesterase 5A inhibitor
PF-00489791
×
Maximum Phase:
2
First Approval:
None
UNII:
2S27T3DSZ3
Molecule Type:
Small molecule
Molecular Formula:
C20H28N8O4S
Molecular Weight:
476.56
AlogP:
1.46
PSA:
144.23
HBD:
2.0
HBA:
#RotB:
10.0
Source:
ORM-12741
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Unknown
ORM-12741
×
Maximum Phase:
2
First Approval:
None
UNII:
D26C95A960
Molecule Type:
Small molecule
Molecular Formula:
C18H23NO2
Molecular Weight:
285.39
AlogP:
3.78
PSA:
25.61
HBD:
0.0
HBA:
#RotB:
2.0
Source:
PICTILISIB
2
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin; Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung
PI3-kinase class I inhibitor
PICTILISIB
×
Maximum Phase:
2
First Approval:
None
UNII:
ICY00EMP8P
Molecule Type:
Small molecule
Molecular Formula:
C23H27N7O3S2
Molecular Weight:
513.65
AlogP:
2.15
PSA:
107.55
HBD:
1.0
HBA:
#RotB:
5.0
Source:
UC1010
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
UC1010
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DEXTOFISOPAM
2
Small molecule
Investigational
Unknown
Unknown
Irritable Bowel Syndrome
Unknown
DEXTOFISOPAM
×
Maximum Phase:
2
First Approval:
None
UNII:
EZ15I5D6C1
Molecule Type:
Small molecule
Molecular Formula:
C22H26N2O4
Molecular Weight:
382.46
AlogP:
4.44
PSA:
61.64
HBD:
0.0
HBA:
#RotB:
6.0
Source:
APILIMOD
2
Small molecule
Investigational
Unknown
Unknown
Common Variable Immunodeficiency; Crohn Disease; Severe Acute Respiratory Syndrome
1-phosphatidylinositol 3-phosphate 5-kinase inhibitor
APILIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
GFW2K84S4L
Molecule Type:
Small molecule
Molecular Formula:
C23H26N6O2
Molecular Weight:
418.5
AlogP:
3.08
PSA:
84.76
HBD:
1.0
HBA:
#RotB:
8.0
Source:
GW468816
2
Small molecule
Investigational
Unknown
Unknown
Tobacco Use Disorder
Glutamate [NMDA] receptor antagonist
GW468816
×
Maximum Phase:
2
First Approval:
None
UNII:
3WGI8FOO62
Molecule Type:
Small molecule
Molecular Formula:
C20H17ClN2O3
Molecular Weight:
368.82
AlogP:
3.8
PSA:
69.64
HBD:
2.0
HBA:
#RotB:
2.0
Source:
PF-4191834
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Osteoarthritis, Knee
Arachidonate 5-lipoxygenase inhibitor
PF-4191834
×
Maximum Phase:
2
First Approval:
None
UNII:
YX55DXP4T1
Molecule Type:
Small molecule
Molecular Formula:
C22H23N3O2S
Molecular Weight:
393.51
AlogP:
3.77
PSA:
70.14
HBD:
1.0
HBA:
#RotB:
5.0
Source:
SQ109
2
Small molecule
Investigational
Unknown
Unknown
Helicobacter Infections; Tuberculosis
Unknown
SQ109
×
Maximum Phase:
2
First Approval:
None
UNII:
9AU7XUV31A
Molecule Type:
Small molecule
Molecular Formula:
C22H38N2
Molecular Weight:
330.56
AlogP:
4.68
PSA:
24.06
HBD:
2.0
HBA:
#RotB:
9.0
Source:
FLUOROFURANYLNORPROGESTERONE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FLUOROFURANYLNORPROGESTERONE
×
Maximum Phase:
2
First Approval:
None
UNII:
K56K9G4PPM
Molecule Type:
Small molecule
Molecular Formula:
C25H29FO5
Molecular Weight:
428.5
AlogP:
4.72
PSA:
65.74
HBD:
0.0
HBA:
#RotB:
3.0
Source:
TONABERSAT
2
Small molecule
Investigational
Unknown
Unknown
Migraine with Aura; Migraine without Aura
Unknown
TONABERSAT
×
Maximum Phase:
2
First Approval:
None
UNII:
2XD9773ZMN
Molecule Type:
Small molecule
Molecular Formula:
C20H19ClFNO4
Molecular Weight:
391.83
AlogP:
3.68
PSA:
75.63
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PROPIONIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PROPIONIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
JHU490RVYR
Molecule Type:
Small molecule
Molecular Formula:
C3H6O2
Molecular Weight:
74.08
AlogP:
0.48
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
1.0
Source:
TIPEPIDINE
2
Small molecule
Investigational
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity; Cough; Depressive Disorder
Unknown
TIPEPIDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
2260ZP67IT
Molecule Type:
Small molecule
Molecular Formula:
C15H17NS2
Molecular Weight:
275.44
AlogP:
4.34
PSA:
3.24
HBD:
0.0
HBA:
#RotB:
2.0
Source:
ME-401
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ME-401
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INECALCITOL
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute
Vitamin D receptor agonist
INECALCITOL
×
Maximum Phase:
2
First Approval:
None
UNII:
05FZV98342
Molecule Type:
Small molecule
Molecular Formula:
C26H40O3
Molecular Weight:
400.6
AlogP:
4.76
PSA:
60.69
HBD:
3.0
HBA:
#RotB:
3.0
Source:
AZD5672
2
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases; Arthritis, Rheumatoid
C-C chemokine receptor type 5 antagonist
AZD5672
×
Maximum Phase:
2
First Approval:
None
UNII:
61XQN688TW
Molecule Type:
Small molecule
Molecular Formula:
C31H43F2N3O5S2
Molecular Weight:
639.83
AlogP:
4.07
PSA:
95.07
HBD:
0.0
HBA:
#RotB:
11.0
Source:
ETHION
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ETHION
×
Maximum Phase:
2
First Approval:
None
UNII:
2TI07NO12Y
Molecule Type:
Small molecule
Molecular Formula:
C9H22O4P2S4
Molecular Weight:
384.49
AlogP:
5.01
PSA:
36.92
HBD:
0.0
HBA:
#RotB:
12.0
Source:
OC000459
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Dermatitis, Atopic; Eosinophilic Esophagitis; Rhinitis, Allergic, Seasonal
G protein-coupled receptor 44 antagonist
OC000459
×
Maximum Phase:
2
First Approval:
None
UNII:
04XB9TB8OL
Molecule Type:
Small molecule
Molecular Formula:
C21H17FN2O2
Molecular Weight:
348.38
AlogP:
4.31
PSA:
55.12
HBD:
1.0
HBA:
#RotB:
4.0
Source:
GALUNISERTIB
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Glioma; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Carcinoma, Hepatocellular; Glioblastoma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms
TGF-beta receptor type I inhibitor
GALUNISERTIB
×
Maximum Phase:
2
First Approval:
None
UNII:
3OKH1W5LZE
Molecule Type:
Small molecule
Molecular Formula:
C22H19N5O
Molecular Weight:
369.43
AlogP:
3.51
PSA:
86.69
HBD:
1.0
HBA:
#RotB:
3.0
Source:
SONEDENOSON
2
Small molecule
Investigational
Unknown
Unknown
Diabetic Foot
Adenosine A2a receptor agonist
SONEDENOSON
×
Maximum Phase:
2
First Approval:
None
UNII:
2OT4KAG5JL
Molecule Type:
Small molecule
Molecular Formula:
C18H20ClN5O5
Molecular Weight:
421.84
AlogP:
0.29
PSA:
148.77
HBD:
4.0
HBA:
#RotB:
6.0
Source:
OLEIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Glioma; Multiple Sclerosis; Adenoma
Unknown
OLEIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
2UMI9U37CP
Molecule Type:
Small molecule
Molecular Formula:
C18H34O2
Molecular Weight:
282.47
AlogP:
6.11
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
15.0
Source:
1
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Molecular Weight
ALogP
PSA