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ENT (5)
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GASTROINTESTINAL (29)
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NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
AZD2423
2
Small molecule
Investigational
Unknown
Unknown
Neuralgia; Pain; Pulmonary Disease, Chronic Obstructive
C-C chemokine receptor type 2 antagonist
AZD2423
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IBUTAMOREN MESYLATE
2
Small molecule
Investigational
Unknown
Unknown
Fibromyalgia
Ghrelin receptor agonist
IBUTAMOREN MESYLATE
×
Maximum Phase:
2
First Approval:
None
UNII:
R90JB6QJ2B
Molecule Type:
Small molecule
Molecular Formula:
C28H40N4O8S2
Molecular Weight:
624.78
AlogP:
1.77
PSA:
122.04
HBD:
2.0
HBA:
#RotB:
8.0
Source:
N-METHYL-D-ASPARTIC ACID (NMDA)
2
Small molecule
Investigational
Unknown
Unknown
Brain Injuries; Borderline Personality Disorder; Depressive Disorder, Major
Unknown
N-METHYL-D-ASPARTIC ACID (NMDA)
×
Maximum Phase:
2
First Approval:
None
UNII:
1903B9Q6PI
Molecule Type:
Small molecule
Molecular Formula:
C5H9NO4
Molecular Weight:
147.13
AlogP:
-0.87
PSA:
86.63
HBD:
3.0
HBA:
#RotB:
4.0
Source:
UPADACITINIB TARTRATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
UPADACITINIB TARTRATE
×
Maximum Phase:
2
First Approval:
None
UNII:
7KCW9IQM02
Molecule Type:
Small molecule
Molecular Formula:
C21H33F3N6O11
Molecular Weight:
602.52
AlogP:
2.91
PSA:
78.32
HBD:
2.0
HBA:
#RotB:
3.0
Source:
DOTANOC
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
DOTANOC
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TALSACLIDINE
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Muscarinic acetylcholine receptor M1 agonist
TALSACLIDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
1O8VSL798T
Molecule Type:
Small molecule
Molecular Formula:
C10H15NO
Molecular Weight:
165.24
AlogP:
0.73
PSA:
12.47
HBD:
0.0
HBA:
#RotB:
2.0
Source:
JNJ-26489112
2
Small molecule
Investigational
Unknown
Unknown
Epilepsy, Reflex
Unknown
JNJ-26489112
×
Maximum Phase:
2
First Approval:
None
UNII:
G1TI012DLT
Molecule Type:
Small molecule
Molecular Formula:
C9H11ClN2O4S
Molecular Weight:
278.72
AlogP:
0.27
PSA:
90.65
HBD:
2.0
HBA:
#RotB:
3.0
Source:
CHLOROGENIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Lung Neoplasms; Neoplasms; Glioblastoma; Glucose Intolerance
Unknown
CHLOROGENIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
318ADP12RI
Molecule Type:
Small molecule
Molecular Formula:
C16H18O9
Molecular Weight:
354.31
AlogP:
-0.65
PSA:
164.75
HBD:
6.0
HBA:
#RotB:
4.0
Source:
LIDORESTAT
2
Small molecule
Investigational
Unknown
Unknown
Diabetic Neuropathies
Unknown
LIDORESTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
R3734K0M7L
Molecule Type:
Small molecule
Molecular Formula:
C18H11F3N2O2S
Molecular Weight:
376.36
AlogP:
4.34
PSA:
55.12
HBD:
1.0
HBA:
#RotB:
4.0
Source:
GPX-100
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GPX-100
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DOLASTATIN 10
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
DOLASTATIN 10
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ETIOPURPURIN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ETIOPURPURIN
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C37H44N4O2
Molecular Weight:
576.79
AlogP:
8.81
PSA:
83.66
HBD:
2.0
HBA:
#RotB:
6.0
Source:
BECOCALCIDIOL
2
Small molecule
Investigational
Unknown
Unknown
Psoriasis
Vitamin D receptor agonist
BECOCALCIDIOL
×
Maximum Phase:
2
First Approval:
None
UNII:
N75R59YD0F
Molecule Type:
Small molecule
Molecular Formula:
C23H36O2
Molecular Weight:
344.54
AlogP:
5.17
PSA:
40.46
HBD:
2.0
HBA:
#RotB:
3.0
Source:
APD371
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
APD371
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ACORAFLOXACIN HYDROCHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Infections; Pneumonia, Bacterial
Unknown
ACORAFLOXACIN HYDROCHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
1NWW5SKQ0N
Molecule Type:
Small molecule
Molecular Formula:
C21H24ClF2N3O4
Molecular Weight:
455.89
AlogP:
2.96
PSA:
97.79
HBD:
2.0
HBA:
#RotB:
5.0
Source:
UPRIFOSBUVIR
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Unknown
UPRIFOSBUVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
JW31KPS26S
Molecule Type:
Small molecule
Molecular Formula:
C22H29ClN3O9P
Molecular Weight:
545.91
AlogP:
1.93
PSA:
158.18
HBD:
3.0
HBA:
#RotB:
10.0
Source:
AZD-4877
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms
Kinesin-like protein 1 inhibitor
AZD-4877
×
Maximum Phase:
2
First Approval:
None
UNII:
19ORU63E06
Molecule Type:
Small molecule
Molecular Formula:
C28H33N5O2S
Molecular Weight:
503.67
AlogP:
4.71
PSA:
94.11
HBD:
1.0
HBA:
#RotB:
9.0
Source:
PHENCYNONATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PHENCYNONATE
×
Maximum Phase:
2
First Approval:
None
UNII:
H84F112WBJ
Molecule Type:
Small molecule
Molecular Formula:
C22H31NO3
Molecular Weight:
357.49
AlogP:
3.34
PSA:
49.77
HBD:
1.0
HBA:
#RotB:
4.0
Source:
GSK-232802
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GSK-232802
×
Maximum Phase:
2
First Approval:
None
UNII:
AG92SGO434
Molecule Type:
Small molecule
Molecular Formula:
C24H28O3
Molecular Weight:
364.49
AlogP:
6.13
PSA:
57.53
HBD:
2.0
HBA:
#RotB:
3.0
Source:
TNP-470
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
TNP-470
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CP1-1189
2
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
CP1-1189
×
Maximum Phase:
2
First Approval:
None
UNII:
9JX1L8VH4Z
Molecule Type:
Small molecule
Molecular Formula:
C13H18N2O2
Molecular Weight:
234.3
AlogP:
2.17
PSA:
58.2
HBD:
2.0
HBA:
#RotB:
2.0
Source:
GSK2982772
2
Small molecule
Investigational
Unknown
Unknown
Immune System Diseases; Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Colitis, Ulcerative; Psoriasis
Unknown
GSK2982772
×
Maximum Phase:
2
First Approval:
None
UNII:
T5W3M0VO9B
Molecule Type:
Small molecule
Molecular Formula:
C20H19N5O3
Molecular Weight:
377.4
AlogP:
1.55
PSA:
100.21
HBD:
2.0
HBA:
#RotB:
4.0
Source:
PF-04457845
2
Small molecule
Investigational
Unknown
Unknown
Chronic Pain; Tourette Syndrome; Marijuana Abuse; Osteoarthritis, Knee; Stress Disorders, Post-Traumatic
Anandamide amidohydrolase inhibitor
PF-04457845
×
Maximum Phase:
2
First Approval:
None
UNII:
H4C81M8YYW
Molecule Type:
Small molecule
Molecular Formula:
C23H20F3N5O2
Molecular Weight:
455.44
AlogP:
5.39
PSA:
80.24
HBD:
1.0
HBA:
#RotB:
4.0
Source:
BICYCLOL
2
Small molecule
Investigational
Unknown
Unknown
Wounds and Injuries
Unknown
BICYCLOL
×
Maximum Phase:
2
First Approval:
None
UNII:
9734122TH2
Molecule Type:
Small molecule
Molecular Formula:
C19H18O9
Molecular Weight:
390.34
AlogP:
2.11
PSA:
101.91
HBD:
1.0
HBA:
#RotB:
5.0
Source:
ISPRONICLINE
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Attention Deficit Disorder with Hyperactivity; Memory Disorders; Schizophrenia
Neuronal acetylcholine receptor; alpha4/beta2 partial agonist
ISPRONICLINE
×
Maximum Phase:
2
First Approval:
None
UNII:
3E05NBH9V5
Molecule Type:
Small molecule
Molecular Formula:
C14H22N2O
Molecular Weight:
234.34
AlogP:
2.88
PSA:
34.15
HBD:
1.0
HBA:
#RotB:
6.0
Source:
ADL-5859
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Osteoarthritis, Knee; Pain
Unknown
ADL-5859
×
Maximum Phase:
2
First Approval:
None
UNII:
FA554TW3UP
Molecule Type:
Small molecule
Molecular Formula:
C24H28N2O3
Molecular Weight:
392.5
AlogP:
3.82
PSA:
61.8
HBD:
2.0
HBA:
#RotB:
4.0
Source:
IROSUSTAT
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Endometrial Neoplasms
Steryl-sulfatase inhibitor
IROSUSTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
366037O6O7
Molecule Type:
Small molecule
Molecular Formula:
C14H15NO5S
Molecular Weight:
309.34
AlogP:
1.64
PSA:
99.6
HBD:
1.0
HBA:
#RotB:
2.0
Source:
PF-03654764
2
Small molecule
Investigational
Unknown
Unknown
Rhinitis, Allergic, Seasonal
Histamine H3 receptor antagonist
PF-03654764
×
Maximum Phase:
2
First Approval:
None
UNII:
FPI2G03BJ1
Molecule Type:
Small molecule
Molecular Formula:
C20H28F2N2O
Molecular Weight:
350.45
AlogP:
3.77
PSA:
32.34
HBD:
1.0
HBA:
#RotB:
6.0
Source:
NOX-100
2
Small molecule
Investigational
Unknown
Unknown
Hypotension
Unknown
NOX-100
×
Maximum Phase:
2
First Approval:
None
UNII:
7WFB66H4LB
Molecule Type:
Small molecule
Molecular Formula:
C8H17NO5S2
Molecular Weight:
271.36
AlogP:
-2.43
PSA:
104.39
HBD:
6.0
HBA:
#RotB:
6.0
Source:
PF-06882961
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PF-06882961
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TRIPLATIN TETRANITRATE
2
Small molecule
Investigational
Unknown
Unknown
Lung Neoplasms; Pancreatic Neoplasms
Unknown
TRIPLATIN TETRANITRATE
×
Maximum Phase:
2
First Approval:
None
UNII:
HAJ1000ARC
Molecule Type:
Small molecule
Molecular Formula:
C12H50Cl2N14O12Pt3
Molecular Weight:
1238.76
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
VK5211
2
Small molecule
Investigational
Unknown
Unknown
Hip Fractures
Androgen Receptor modulator
VK5211
×
Maximum Phase:
2
First Approval:
None
UNII:
1EJT54415A
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
EFATUTAZONE
2
Small molecule
Investigational
Unknown
Unknown
Multiple Myeloma; Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Liposarcoma; Thyroid Neoplasms
Unknown
EFATUTAZONE
×
Maximum Phase:
2
First Approval:
None
UNII:
M17ILL71MC
Molecule Type:
Small molecule
Molecular Formula:
C27H26N4O4S
Molecular Weight:
502.6
AlogP:
5.04
PSA:
108.47
HBD:
2.0
HBA:
#RotB:
7.0
Source:
AZD2207
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Cannabinoid CB1 receptor antagonist
AZD2207
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C22H22Cl2F2N4O3+2
Molecular Weight:
499.35
AlogP:
3.67
PSA:
89.35
HBD:
4.0
HBA:
#RotB:
8.0
Source:
URIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Ischemic Stroke
Unknown
URIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
268B43MJ25
Molecule Type:
Small molecule
Molecular Formula:
C5H4N4O3
Molecular Weight:
168.11
AlogP:
-0.53
PSA:
115.15
HBD:
4.0
HBA:
#RotB:
0.0
Source:
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Molecular Formula
Molecular Weight
ALogP
PSA