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Therapeutic Area
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CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
PAMAPIMOD
2
Small molecule
Investigational
Unknown
Unknown
Unknown
MAP kinase p38 alpha inhibitor
PAMAPIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
8S2C9V11K4
Molecule Type:
Small molecule
Molecular Formula:
C19H20F2N4O4
Molecular Weight:
406.39
AlogP:
1.94
PSA:
109.5
HBD:
3.0
HBA:
#RotB:
8.0
Source:
BRECANAVIR
2
Small molecule
Investigational
Unknown
Unknown
HIV Infections
HIV-1 protease inhibitor
BRECANAVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
E367I8C7FI
Molecule Type:
Small molecule
Molecular Formula:
C33H41N3O10S2
Molecular Weight:
703.84
AlogP:
3.87
PSA:
154.98
HBD:
2.0
HBA:
#RotB:
14.0
Source:
BMS-833923
2
Small molecule
Investigational
Unknown
Unknown
Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Esophageal Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Leukemia
Smoothened homolog antagonist
BMS-833923
×
Maximum Phase:
2
First Approval:
None
UNII:
41J7ZJ239R
Molecule Type:
Small molecule
Molecular Formula:
C30H27N5O
Molecular Weight:
473.58
AlogP:
6.32
PSA:
78.94
HBD:
3.0
HBA:
#RotB:
7.0
Source:
FOSLINANIB
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma; Neoplasms; Carcinoma, Hepatocellular
Unknown
FOSLINANIB
×
Maximum Phase:
2
First Approval:
None
UNII:
2X2DNM7NGX
Molecule Type:
Small molecule
Molecular Formula:
C16H13FNO6P
Molecular Weight:
365.25
AlogP:
2.81
PSA:
108.85
HBD:
3.0
HBA:
#RotB:
4.0
Source:
SUNOBINOP
2
Small molecule
Investigational
Unknown
Unknown
Pain; Sleep Initiation and Maintenance Disorders
Unknown
SUNOBINOP
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C26H33N3O3
Molecular Weight:
435.57
AlogP:
4.62
PSA:
75.43
HBD:
1.0
HBA:
#RotB:
3.0
Source:
BRYOSTATIN 1
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BRYOSTATIN 1
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TONAPOFYLLINE
2
Small molecule
Investigational
Unknown
Unknown
Liver Diseases; Heart Failure; Renal Insufficiency
Adenosine A1 receptor antagonist
TONAPOFYLLINE
×
Maximum Phase:
2
First Approval:
None
UNII:
83VNU4U44T
Molecule Type:
Small molecule
Molecular Formula:
C22H32N4O4
Molecular Weight:
416.52
AlogP:
3.16
PSA:
109.98
HBD:
2.0
HBA:
#RotB:
8.0
Source:
IDOXIFENE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Estrogen receptor modulator
IDOXIFENE
×
Maximum Phase:
2
First Approval:
None
UNII:
456UXE9867
Molecule Type:
Small molecule
Molecular Formula:
C28H30INO
Molecular Weight:
523.46
AlogP:
7.13
PSA:
12.47
HBD:
0.0
HBA:
#RotB:
8.0
Source:
LY2196044
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LY2196044
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LAZUVAPAGON
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LAZUVAPAGON
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C27H32N4O3
Molecular Weight:
460.58
AlogP:
3.59
PSA:
87.46
HBD:
2.0
HBA:
#RotB:
5.0
Source:
SIMUROSERTIB
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Cell division cycle 7-related protein kinase inhibitor
SIMUROSERTIB
×
Maximum Phase:
2
First Approval:
None
UNII:
LST350G3XU
Molecule Type:
Small molecule
Molecular Formula:
C17H19N5OS
Molecular Weight:
341.44
AlogP:
2.84
PSA:
77.67
HBD:
2.0
HBA:
#RotB:
2.0
Source:
MESDOPETAM
2
Small molecule
Investigational
Unknown
Unknown
Parkinson Disease
Unknown
MESDOPETAM
×
Maximum Phase:
2
First Approval:
None
UNII:
HD4QV8GX26
Molecule Type:
Small molecule
Molecular Formula:
C12H18FNO3S
Molecular Weight:
275.35
AlogP:
1.61
PSA:
55.4
HBD:
1.0
HBA:
#RotB:
7.0
Source:
RAZUPROTAFIB
2
Small molecule
Investigational
Unknown
Unknown
Retinal Vein Occlusion
Receptor-type tyrosine-protein phosphatase beta inhibitor
RAZUPROTAFIB
×
Maximum Phase:
2
First Approval:
None
UNII:
0WAX4UT396
Molecule Type:
Small molecule
Molecular Formula:
C26H26N4O6S3
Molecular Weight:
586.72
AlogP:
4.45
PSA:
146.72
HBD:
4.0
HBA:
#RotB:
11.0
Source:
OLOROFIM
2
Small molecule
Investigational
Unknown
Unknown
Aspergillosis; Leukemia, Myeloid, Acute; Liver Diseases; Mycoses
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibitor
OLOROFIM
×
Maximum Phase:
2
First Approval:
None
UNII:
T34SH2H9HI
Molecule Type:
Small molecule
Molecular Formula:
C28H27FN6O2
Molecular Weight:
498.56
AlogP:
4.08
PSA:
83.36
HBD:
1.0
HBA:
#RotB:
6.0
Source:
CARMOTEROL
2
Small molecule
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
CARMOTEROL
×
Maximum Phase:
2
First Approval:
None
UNII:
9810NUL4D1
Molecule Type:
Small molecule
Molecular Formula:
C21H24N2O4
Molecular Weight:
368.43
AlogP:
2.5
PSA:
94.58
HBD:
4.0
HBA:
#RotB:
7.0
Source:
DWP05195
2
Small molecule
Investigational
Unknown
Unknown
Neuralgia, Postherpetic
Vanilloid receptor antagonist
DWP05195
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DELTA 8-TETRAHYDROCANNOBINOL
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
DELTA 8-TETRAHYDROCANNOBINOL
×
Maximum Phase:
2
First Approval:
None
UNII:
B49D0HH807
Molecule Type:
Small molecule
Molecular Formula:
C21H30O2
Molecular Weight:
314.47
AlogP:
5.74
PSA:
29.46
HBD:
1.0
HBA:
#RotB:
4.0
Source:
TARTRATE
2
Small molecule
Investigational
Unknown
Unknown
Dementia
Unknown
TARTRATE
×
Maximum Phase:
2
First Approval:
None
UNII:
4J4Z8788N8
Molecule Type:
Small molecule
Molecular Formula:
C4H6O6
Molecular Weight:
150.09
AlogP:
-2.12
PSA:
115.06
HBD:
4.0
HBA:
#RotB:
3.0
Source:
(-)-EPICATECHIN
2
Small molecule
Investigational
Unknown
Unknown
Hypertension, Pulmonary; Muscular Dystrophy, Duchenne
Unknown
(-)-EPICATECHIN
×
Maximum Phase:
2
First Approval:
None
UNII:
34PHS7TU43
Molecule Type:
Small molecule
Molecular Formula:
C15H14O6
Molecular Weight:
290.27
AlogP:
1.55
PSA:
110.38
HBD:
5.0
HBA:
#RotB:
1.0
Source:
AMISELIMOD
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AMISELIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
358M5150LY
Molecule Type:
Small molecule
Molecular Formula:
C19H30F3NO3
Molecular Weight:
377.45
AlogP:
3.67
PSA:
75.71
HBD:
3.0
HBA:
#RotB:
12.0
Source:
PEGAMOTECAN
2
Small molecule
Investigational
Unknown
Unknown
Sarcoma
Unknown
PEGAMOTECAN
×
Maximum Phase:
2
First Approval:
None
UNII:
ZY7ZTE7LFH
Molecule Type:
Small molecule
Molecular Formula:
C52H48N6O14
Molecular Weight:
980.98
AlogP:
3.32
PSA:
251.64
HBD:
2.0
HBA:
#RotB:
15.0
Source:
RUZASVIR
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Nonstructural protein 5A inhibitor
RUZASVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
LX752BD95Y
Molecule Type:
Small molecule
Molecular Formula:
C49H56N10O7S
Molecular Weight:
929.12
AlogP:
8.45
PSA:
201.69
HBD:
4.0
HBA:
#RotB:
12.0
Source:
NAXIFYLLINE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Adenosine A1 receptor antagonist
NAXIFYLLINE
×
Maximum Phase:
2
First Approval:
None
UNII:
B3G45WC37L
Molecule Type:
Small molecule
Molecular Formula:
C18H24N4O3
Molecular Weight:
344.42
AlogP:
1.6
PSA:
85.21
HBD:
1.0
HBA:
#RotB:
5.0
Source:
CHIAURANIB
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular; Lymphoma, Non-Hodgkin; Neoplasms; Ovarian Neoplasms; Small Cell Lung Carcinoma
Serine/threonine-protein kinase Aurora-B inhibitor
CHIAURANIB
×
Maximum Phase:
2
First Approval:
None
UNII:
F40IRN5981
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INS316
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
INS316
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BALOXAVIR
2
Small molecule
Investigational
Unknown
Unknown
Influenza, Human
Polymerase acidic protein inhibitor
BALOXAVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
4G86Y4JT3F
Molecule Type:
Small molecule
Molecular Formula:
C24H19F2N3O4S
Molecular Weight:
483.5
AlogP:
2.98
PSA:
75.01
HBD:
1.0
HBA:
#RotB:
1.0
Source:
GSK2110183
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GSK2110183
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CIFORADENANT
2
Small molecule
Investigational
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity; Carcinoma, Non-Small-Cell Lung; Multiple Myeloma; Parkinson Disease
Adenosine A2a receptor antagonist
CIFORADENANT
×
Maximum Phase:
2
First Approval:
None
UNII:
8KFO2187CP
Molecule Type:
Small molecule
Molecular Formula:
C20H21N7O3
Molecular Weight:
407.43
AlogP:
2.12
PSA:
127.0
HBD:
1.0
HBA:
#RotB:
6.0
Source:
TOCLADESINE
2
Small molecule
Investigational
Unknown
Unknown
Colorectal Neoplasms; Multiple Myeloma
Unknown
TOCLADESINE
×
Maximum Phase:
2
First Approval:
None
UNII:
BQ94Z7E5OR
Molecule Type:
Small molecule
Molecular Formula:
C10H11ClN5O6P
Molecular Weight:
363.65
AlogP:
-0.16
PSA:
154.84
HBD:
3.0
HBA:
#RotB:
1.0
Source:
ANTIMONY CATION (5+)
2
Small molecule
Investigational
Unknown
Unknown
Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous
Unknown
ANTIMONY CATION (5+)
×
Maximum Phase:
2
First Approval:
None
UNII:
841L03HG64
Molecule Type:
Small molecule
Molecular Formula:
Sb+5
Molecular Weight:
121.76
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
SSR-150106
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid
Unknown
SSR-150106
×
Maximum Phase:
2
First Approval:
None
UNII:
5WX0OAF07I
Molecule Type:
Small molecule
Molecular Formula:
C23H21F3N2
Molecular Weight:
382.43
AlogP:
5.59
PSA:
16.13
HBD:
0.0
HBA:
#RotB:
4.0
Source:
VALOPICITABINE DIHYDROCHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C, Chronic
Unknown
VALOPICITABINE DIHYDROCHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
7KNU786IT4
Molecule Type:
Small molecule
Molecular Formula:
C15H26Cl2N4O6
Molecular Weight:
429.3
AlogP:
-1.64
PSA:
162.92
HBD:
4.0
HBA:
#RotB:
5.0
Source:
PEGCANTRATINIB
2
Small molecule
Investigational
Unknown
Unknown
Neuralgia; Dermatitis, Atopic; Psoriasis
Nerve growth factor receptor Trk-A inhibitor
PEGCANTRATINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
VG44NU1168
Molecule Type:
Small molecule
Molecular Formula:
C30H24N4O6
Molecular Weight:
536.54
AlogP:
4.12
PSA:
104.03
HBD:
1.0
HBA:
#RotB:
3.0
Source:
MK-0777
2
Small molecule
Investigational
Unknown
Unknown
Anxiety; Anxiety Disorders; Schizophrenia
Unknown
MK-0777
×
Maximum Phase:
2
First Approval:
None
UNII:
1FI3KTC550
Molecule Type:
Small molecule
Molecular Formula:
C20H22FN7O
Molecular Weight:
395.44
AlogP:
3.42
PSA:
83.02
HBD:
0.0
HBA:
#RotB:
5.0
Source:
SODIUM PROPIONATE
2
Small molecule
Investigational
Unknown
Unknown
Eye Infections
Unknown
SODIUM PROPIONATE
×
Maximum Phase:
2
First Approval:
None
UNII:
DK6Y9P42IN
Molecule Type:
Small molecule
Molecular Formula:
C3H5NaO2
Molecular Weight:
96.06
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
1
2
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134
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Compound Name
Maximum Phase
Compound Structure
Smile
Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA