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Total: 6532
Small molecule
Approved
OTHER
ORAL
Leukemia, Myeloid, Acute; Carcinoma, Non-Small-Cell Lung; Gastroesophageal Reflux; Severe Acute Respiratory Syndrome; Toxoplasmosis, Cerebral; Malaria, Falciparum; Malaria; Pneumocystis Infections; Pneumonia, Pneumocystis
Cytochrome b inhibitor
Small molecule
Approved
Unknown
Unknown
Asthma; Eye Manifestations; Lung Diseases, Obstructive; Nasal Obstruction
Unknown
Small molecule
Unknown
Unknown
Unknown
Rhabdomyosarcoma; Acute Coronary Syndrome; Oligodendroglioma; Ototoxicity; Renal Insufficiency, Chronic; Calcinosis; Dermatomyositis; Glioma; Head and Neck Neoplasms; Mesothelioma; Hepatoblastoma
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Bacterial DNA gyrase inhibitor
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Tuberculosis, Pulmonary; Crohn Disease; Infections; Mycobacterium Infections; Mycoses; HIV Infections; Mycobacterium avium-intracellulare Infection; Tuberculosis
Bacterial DNA-directed RNA polymerase inhibitor
Small molecule
Approved
IMMUNE SYSTEM; OTHER
INJECTION; ORAL
Esophageal Neoplasms; Alzheimer Disease; Asthma; Cachexia; Celiac Disease; Cystic Fibrosis; Glioblastoma; Heart Failure; Hepatitis B, Chronic; Hepatitis C, Chronic; Infections; Inflammatory Bowel Diseases; Leukemia, Myeloid, Acute; Lymphoma; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Myelodysplastic Syndromes; Neoplasm Metastasis; Neuralgia; Polycystic Ovary Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Syncytial Virus Infections; Sporotrichosis; Thrombosis; Aspergillosis, Allergic Bronchopulmonary; Burns; Carcinoma, Basal Cell; Carcinoma, Non-Small-Cell Lung; Coccidioidomycosis; Hematologic Diseases; Lung Neoplasms; Meningitis, Cryptococcal; Mycetoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Sinusitis; Tinea Pedis; Tinea Versicolor; Cryptococcosis; Histoplasmosis; Neoplasms; Ovarian Neoplasms; Aspergillosis; Blastomycosis; Candidiasis; Lung Diseases; Mycoses; Onychomycosis
Cytochrome P450 51 inhibitor
Small molecule
Approved
Unknown
Unknown
Melanosis; Skin Neoplasms; Sunburn
Unknown
Small molecule
Approved
Unknown
Unknown
Atrial Fibrillation; Death, Sudden, Cardiac; Heart Failure; Myocardial Infarction; Tachycardia, Ventricular; Ventricular Fibrillation; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Dystonic Disorders; Marijuana Abuse; Obesity; Prostatic Neoplasms; Parkinson Disease; Substance-Related Disorders; Anxiety; Attention Deficit Disorder with Hyperactivity; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders
Unknown
Small molecule
Approved
Unknown
Unknown
Sleep Apnea, Central; Amenorrhea; Hemorrhage; Polycystic Ovary Syndrome
Progesterone receptor agonist
Small molecule
Approved
Unknown
Unknown
Unknown
Diagnostic agent
Small molecule
Approved
OTHER
ORAL
Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases
Cyclooxygenase inhibitor
Small molecule
Approved
Unknown
Unknown
Osteomyelitis; Bacterial Infections; Eye Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Erectile Dysfunction; HIV Infections; Hyperlipidemias; Kidney Diseases; Pancreatitis; Aortic Aneurysm, Abdominal; beta-Thalassemia; Cardiomyopathy, Hypertrophic; Dystonic Disorders; Heart Diseases; Hyperaldosteronism; Liver Diseases; Raynaud Disease; Thalassemia; Atherosclerosis; Coronary Disease; Depressive Disorder; Diabetes Mellitus; Diabetes Mellitus, Type 2; Essential Hypertension; Heart Failure; Hypercholesterolemia; Hypertension; Myocardial Infarction; Myocardial Ischemia; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Malaria
Unknown
Small molecule
Unknown
Unknown
Unknown
Atrial Fibrillation; Heart Failure; Arrhythmias, Cardiac
Beta-1 adrenergic receptor antagonist
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Coronary Disease; Hemorrhage; Familial Primary Pulmonary Hypertension; Lecithin Cholesterol Acyltransferase Deficiency; Breast Neoplasms; Hypertension; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
OPHTHALMIC
Unknown
Unknown
Small molecule
Approved
OTHER
INJECTION; ORAL
Diabetes Mellitus, Type 2; Pre-Eclampsia; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Stroke
Sodium-(potassium)-chloride cotransporter 2 inhibitor
Small molecule
Approved
Unknown
Unknown
Depressive Disorder, Major; Depressive Disorder
Unknown
Small molecule
Unknown
Unknown
Unknown
Dysmenorrhea; Pulpitis; Stomach Ulcer; Toothache; Acute Pain; Arthritis, Rheumatoid; Migraine Disorders; Osteoarthritis; Pain
Cyclooxygenase inhibitor
Small molecule
Approved
OTHER
INJECTION; ORAL
Central Nervous System Neoplasms; Graft vs Host Disease; Multiple Myeloma; Myeloproliferative Disorders; Blast Crisis; Cholangitis, Sclerosing; Histiocytosis; Histiocytosis, Langerhans-Cell; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Mastocytosis, Systemic; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, T-Cell, Peripheral; Multiple Sclerosis, Relapsing-Remitting; Anemia; Immune System Diseases; Leukemia, Hairy Cell; Multiple Sclerosis; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
INTRAMUSCULAR; ORAL; SUBCUTANEOUS
Opioid-Related Disorders; Substance-Related Disorders; Dyskinesia, Drug-Induced; Huntington Disease; Lecithin Cholesterol Acyltransferase Deficiency; Schizotypal Personality Disorder; Amphetamine-Related Disorders; Child Development Disorders, Pervasive; Cocaine-Related Disorders; Stress Disorders, Post-Traumatic; Tourette Syndrome; Alzheimer Disease; Anxiety; Asperger Syndrome; Attention Deficit and Disruptive Behavior Disorders; Conduct Disorder; Dementia; Dementia, Vascular; Depressive Disorder; Depressive Disorder, Major; Developmental Disabilities; Intellectual Disability; Neurodevelopmental Disorders; Rett Syndrome; Aggression; Autistic Disorder; Bipolar Disorder; Psychotic Disorders; Schizophrenia
Dopamine D2 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Nasal Obstruction
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Amphetamine-Related Disorders; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Aortic Aneurysm, Abdominal; Breast Neoplasms; Neoplasms; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Hypertension; Marfan Syndrome; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Virus Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Digestive System Diseases
Serotonin 4 (5-HT4) receptor agonist
Small molecule
Approved
OTHER
ORAL
Bipolar Disorder; Anemia; Epilepsy; Seizures
Glutamate [NMDA] receptor antagonist
Small molecule
Approved
Unknown
Unknown
Osteomyelitis; Kidney Diseases; Otitis Media; Communicable Diseases; Graft vs Host Disease; Abscess; Cholecystitis, Acute; Diabetic Foot; Enterobacteriaceae Infections; Hematologic Neoplasms; Infections; Pancreatic Neoplasms; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pseudomonas Infections; Pyelonephritis; Sepsis; Shock, Septic; Urinary Tract Infections; Bacterial Infections
Unknown
Small molecule
Approved
IMMUNE SYSTEM; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS
ORAL
Alopecia; Child Development Disorders, Pervasive; Premature Birth; Psychotic Disorders; Abortion, Spontaneous; Anemia, Sickle Cell; Breast Neoplasms; Hyperemesis Gravidarum; Intervertebral Disc Displacement; Low Back Pain; Marijuana Abuse; Mucositis; Multiple Sclerosis; Neoplasms; Opioid-Related Disorders; Paget Disease, Extramammary; Postoperative Complications; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Substance-Related Disorders; Substance Withdrawal Syndrome; Tinnitus; Tobacco Use Disorder; Urinary Bladder Neoplasms; Wounds and Injuries; Alcohol Drinking; Alcoholism; Anxiety; Azoospermia; Carpal Tunnel Syndrome; Chronic Pain; Delirium; Dementia; Depressive Disorder; Diabetic Neuropathies; Dyspepsia; Epilepsies, Partial; Fibromyalgia; Head and Neck Neoplasms; Herpes Zoster; Hot Flashes; Intervertebral Disc Degeneration; Liver Cirrhosis; Neuralgia; Oropharyngeal Neoplasms; Pain; Pelvic Organ Prolapse; Postoperative Nausea and Vomiting; Pruritus; Schizophrenia; Scoliosis; Sleep Initiation and Maintenance Disorders; Tremor; Vomiting; Epilepsy; Neuralgia, Postherpetic; Restless Legs Syndrome; Seizures
Voltage-gated calcium channel modulator
Small molecule
Approved
OTHER
TOPICAL
Carcinoma, Squamous Cell; Keratosis, Actinic; Scleroderma, Localized; Vitiligo; Acne Vulgaris; Dermatitis, Atopic; Eczema; Radiodermatitis; Skin Diseases; Psoriasis
Vitamin D receptor agonist
Small molecule
Approved
CARDIOVASCULAR
ORAL
Bronchopulmonary Dysplasia
Unknown