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DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
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Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
CEP-9722
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Mantle-Cell; Neoplasms
Unknown
CEP-9722
×
Maximum Phase:
1
First Approval:
None
UNII:
B68083E4YG
Molecule Type:
Small molecule
Molecular Formula:
C24H26N4O3
Molecular Weight:
418.5
AlogP:
2.62
PSA:
68.88
HBD:
1.0
HBA:
#RotB:
3.0
Source:
LGD-6972
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
LGD-6972
×
Maximum Phase:
1
First Approval:
None
UNII:
6IJ842I0Z2
Molecule Type:
Small molecule
Molecular Formula:
C43H46N2O5S
Molecular Weight:
702.92
AlogP:
8.83
PSA:
112.57
HBD:
3.0
HBA:
#RotB:
11.0
Source:
CHF4227
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Estrogen receptor modulator
CHF4227
×
Maximum Phase:
1
First Approval:
None
UNII:
1O98089Q9M
Molecule Type:
Small molecule
Molecular Formula:
C30H33NO4
Molecular Weight:
471.6
AlogP:
5.81
PSA:
51.16
HBD:
1.0
HBA:
#RotB:
8.0
Source:
(NORTH)-METHANOCARBATHYMIDINE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
(NORTH)-METHANOCARBATHYMIDINE
×
Maximum Phase:
1
First Approval:
None
UNII:
LTM5S02010
Molecule Type:
Small molecule
Molecular Formula:
C12H16N2O4
Molecular Weight:
252.27
AlogP:
-0.85
PSA:
95.32
HBD:
3.0
HBA:
#RotB:
2.0
Source:
LISAVANBULIN
1
Small molecule
Investigational
Unknown
Unknown
Glioblastoma; Neoplasms
Unknown
LISAVANBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
5PT0QP06X5
Molecule Type:
Small molecule
Molecular Formula:
C26H29N9O3
Molecular Weight:
515.58
AlogP:
2.69
PSA:
190.77
HBD:
4.0
HBA:
#RotB:
13.0
Source:
GSK159802
1
Small molecule
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
GSK159802
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LY2881835
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Free fatty acid receptor 1 agonist
LY2881835
×
Maximum Phase:
1
First Approval:
None
UNII:
LAD0ZG7FFO
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MEZIGDOMIDE
1
Small molecule
Investigational
Unknown
Unknown
Multiple Myeloma
Unknown
MEZIGDOMIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C32H30FN5O4
Molecular Weight:
567.62
AlogP:
3.36
PSA:
105.98
HBD:
1.0
HBA:
#RotB:
7.0
Source:
SEL-120
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SEL-120
×
Maximum Phase:
1
First Approval:
None
UNII:
SDM3M518PJ
Molecule Type:
Small molecule
Molecular Formula:
C15H18Br2N4
Molecular Weight:
414.14
AlogP:
3.23
PSA:
33.09
HBD:
1.0
HBA:
#RotB:
1.0
Source:
RG7893
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Sodium channel protein type IX alpha subunit blocker
RG7893
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SHETA-2
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SHETA-2
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C20H23N3O2S2
Molecular Weight:
401.56
AlogP:
6.18
PSA:
67.53
HBD:
2.0
HBA:
#RotB:
3.0
Source:
NIKKOMYCIN
1
Small molecule
Investigational
Unknown
Unknown
Coccidioidomycosis
Unknown
NIKKOMYCIN
×
Maximum Phase:
1
First Approval:
None
UNII:
9Z22C3QQCJ
Molecule Type:
Small molecule
Molecular Formula:
C20H25N5O10
Molecular Weight:
495.45
AlogP:
-3.48
PSA:
250.32
HBD:
8.0
HBA:
#RotB:
8.0
Source:
ETACONAZOLE
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Prostatic Neoplasms
Unknown
ETACONAZOLE
×
Maximum Phase:
1
First Approval:
None
UNII:
3MT15AE9VG
Molecule Type:
Small molecule
Molecular Formula:
C14H15Cl2N3O2
Molecular Weight:
328.2
AlogP:
3.26
PSA:
49.17
HBD:
0.0
HBA:
#RotB:
4.0
Source:
VLX-1005
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
VLX-1005
×
Maximum Phase:
1
First Approval:
None
UNII:
JKU4XCC48Y
Molecule Type:
Small molecule
Molecular Formula:
C21H19N3O4S2
Molecular Weight:
441.53
AlogP:
4.42
PSA:
100.55
HBD:
3.0
HBA:
#RotB:
7.0
Source:
KW-2450
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Neoplasms
Insulin-like growth factor I receptor inhibitor
KW-2450
×
Maximum Phase:
1
First Approval:
None
UNII:
2TRH1EX32K
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK-2239633
1
Small molecule
Investigational
Unknown
Unknown
Asthma
Unknown
GSK-2239633
×
Maximum Phase:
1
First Approval:
None
UNII:
07ODS257BP
Molecule Type:
Small molecule
Molecular Formula:
C21H19ClN4O5S2
Molecular Weight:
506.99
AlogP:
3.54
PSA:
122.55
HBD:
3.0
HBA:
#RotB:
8.0
Source:
RODATRISTAT ETHYL
1
Small molecule
Investigational
Unknown
Unknown
Hypertension, Pulmonary
Tryptophan 5-hydroxylase 1 inhibitor
RODATRISTAT ETHYL
×
Maximum Phase:
1
First Approval:
None
UNII:
507FY6OL37
Molecule Type:
Small molecule
Molecular Formula:
C29H31ClF3N5O3
Molecular Weight:
590.05
AlogP:
5.57
PSA:
102.6
HBD:
2.0
HBA:
#RotB:
7.0
Source:
LY-3007113
1
Small molecule
Investigational
Unknown
Unknown
Unknown
MAP kinase p38 alpha inhibitor
LY-3007113
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
123I-IODOMETOMIDATE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
123I-IODOMETOMIDATE
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ZOTATIFIN
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Severe Acute Respiratory Syndrome
Unknown
ZOTATIFIN
×
Maximum Phase:
1
First Approval:
None
UNII:
2EWN8Z05CN
Molecule Type:
Small molecule
Molecular Formula:
C28H29N3O5
Molecular Weight:
487.56
AlogP:
2.78
PSA:
108.07
HBD:
2.0
HBA:
#RotB:
6.0
Source:
CLN-081
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
CLN-081
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C23H20N6O
Molecular Weight:
396.45
AlogP:
3.32
PSA:
98.72
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PHE377
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Vanilloid receptor antagonist
PHE377
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BIIF 1149 BS
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BIIF 1149 BS
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VS-4718
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Pancreatic Neoplasms
Focal adhesion kinase 1 inhibitor
VS-4718
×
Maximum Phase:
1
First Approval:
None
UNII:
L2BD0MW4OL
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PF-05105679
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PF-05105679
×
Maximum Phase:
1
First Approval:
None
UNII:
F2B10OFV7Y
Molecule Type:
Small molecule
Molecular Formula:
C26H21FN2O3
Molecular Weight:
428.46
AlogP:
5.48
PSA:
70.5
HBD:
1.0
HBA:
#RotB:
6.0
Source:
BRICICLIB SODIUM
1
Small molecule
Investigational
Unknown
Unknown
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Unknown
BRICICLIB SODIUM
×
Maximum Phase:
1
First Approval:
None
UNII:
7C9N0VM8NR
Molecule Type:
Small molecule
Molecular Formula:
C19H21Na2O10PS
Molecular Weight:
518.39
AlogP:
2.78
PSA:
137.82
HBD:
2.0
HBA:
#RotB:
10.0
Source:
ALOBRESIB
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Lymphoma; Prostatic Neoplasms, Castration-Resistant
Unknown
ALOBRESIB
×
Maximum Phase:
1
First Approval:
None
UNII:
3QBL0BLP3D
Molecule Type:
Small molecule
Molecular Formula:
C26H23N5O2
Molecular Weight:
437.5
AlogP:
4.79
PSA:
100.72
HBD:
2.0
HBA:
#RotB:
5.0
Source:
XL-844
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Neoplasms
Serine/threonine-protein kinase Chk1 inhibitor
XL-844
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FEDOVAPAGON
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FEDOVAPAGON
×
Maximum Phase:
1
First Approval:
None
UNII:
VX2GBO4I0V
Molecule Type:
Small molecule
Molecular Formula:
C27H34N4O3
Molecular Weight:
462.59
AlogP:
3.74
PSA:
72.96
HBD:
1.0
HBA:
#RotB:
4.0
Source:
PEGULICIANINE ACETATE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PEGULICIANINE ACETATE
×
Maximum Phase:
1
First Approval:
None
UNII:
F3F6208UMT
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TALADEGIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasm Metastasis; Neoplasms; Small Cell Lung Carcinoma; Idiopathic Pulmonary Fibrosis
Smoothened homolog antagonist
TALADEGIB
×
Maximum Phase:
1
First Approval:
None
UNII:
QY8BWX1LJ5
Molecule Type:
Small molecule
Molecular Formula:
C26H24F4N6O
Molecular Weight:
512.51
AlogP:
4.93
PSA:
67.15
HBD:
0.0
HBA:
#RotB:
4.0
Source:
PEN-866
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PEN-866
×
Maximum Phase:
1
First Approval:
None
UNII:
56DL1J49LR
Molecule Type:
Small molecule
Molecular Formula:
C49H49N7O9
Molecular Weight:
879.97
AlogP:
6.97
PSA:
207.03
HBD:
4.0
HBA:
#RotB:
9.0
Source:
SNS-062
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SNS-062
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AVE-9940
1
Small molecule
Investigational
Unknown
Unknown
Unknown
MAP kinase p38 alpha inhibitor
AVE-9940
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
D-FLUOROMETHYLTYROSINE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
D-FLUOROMETHYLTYROSINE
×
Maximum Phase:
1
First Approval:
None
UNII:
GSM7N3U4J8
Molecule Type:
Small molecule
Molecular Formula:
C10H12FNO3
Molecular Weight:
213.21
AlogP:
0.95
PSA:
72.55
HBD:
2.0
HBA:
#RotB:
5.0
Source:
1
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68
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Compound Name
Maximum Phase
Compound Structure
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Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA