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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
QBW251
2
Small molecule
Investigational
Unknown
Unknown
Cystic Fibrosis; Pulmonary Disease, Chronic Obstructive
Cystic fibrosis transmembrane conductance regulator activator
QBW251
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MLNM-2201
2
Antibody
Investigational
Unknown
Unknown
Unknown
Integrin beta-2 inhibitor
MLNM-2201
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-986089
2
Protein
Investigational
Unknown
Unknown
Unknown
Unknown
BMS-986089
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BISEGLIPTIN
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Dipeptidyl peptidase IV inhibitor
BISEGLIPTIN
×
Maximum Phase:
2
First Approval:
None
UNII:
9U5KQ79OK6
Molecule Type:
Small molecule
Molecular Formula:
C18H26FN3O3
Molecular Weight:
351.42
AlogP:
1.69
PSA:
82.43
HBD:
1.0
HBA:
#RotB:
5.0
Source:
VERUBULIN
2
Small molecule
Investigational
Unknown
Unknown
Brain Neoplasms; Neoplasms; Glioblastoma
Tubulin disrupting agent
VERUBULIN
×
Maximum Phase:
2
First Approval:
None
UNII:
X97O9FTB92
Molecule Type:
Small molecule
Molecular Formula:
C17H17N3O
Molecular Weight:
279.34
AlogP:
3.71
PSA:
38.25
HBD:
0.0
HBA:
#RotB:
3.0
Source:
FLT
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
FLT
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TRELANSERIN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Serotonin 1b (5-HT1b) receptor antagonist
TRELANSERIN
×
Maximum Phase:
2
First Approval:
None
UNII:
QUD44MBL5S
Molecule Type:
Small molecule
Molecular Formula:
C24H24FN5O2S
Molecular Weight:
465.55
AlogP:
2.6
PSA:
84.46
HBD:
1.0
HBA:
#RotB:
6.0
Source:
PIPENDOXIFENE
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms
Unknown
PIPENDOXIFENE
×
Maximum Phase:
2
First Approval:
None
UNII:
TPC5Q8496G
Molecule Type:
Small molecule
Molecular Formula:
C29H32N2O3
Molecular Weight:
456.59
AlogP:
5.94
PSA:
57.86
HBD:
2.0
HBA:
#RotB:
7.0
Source:
GSK-1521498
2
Small molecule
Investigational
Unknown
Unknown
Alcoholism; Obesity
Mu opioid receptor antagonist
GSK-1521498
×
Maximum Phase:
2
First Approval:
None
UNII:
W0UTB622GK
Molecule Type:
Small molecule
Molecular Formula:
C24H20F2N4
Molecular Weight:
402.45
AlogP:
4.67
PSA:
53.6
HBD:
2.0
HBA:
#RotB:
5.0
Source:
IBERDOMIDE
2
Small molecule
Investigational
Unknown
Unknown
Renal Insufficiency; Multiple Myeloma
CRL4(CRBN) E3 ubiquitin ligase modulator
IBERDOMIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
8V66F27X44
Molecule Type:
Small molecule
Molecular Formula:
C25H27N3O5
Molecular Weight:
449.51
AlogP:
1.86
PSA:
88.18
HBD:
1.0
HBA:
#RotB:
6.0
Source:
HPPH
2
Small molecule
Investigational
Unknown
Unknown
Adenocarcinoma of Lung; Barrett Esophagus; Head and Neck Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Verrucous; Esophageal Neoplasms; Lung Neoplasms; Oropharyngeal Neoplasms; Squamous Cell Carcinoma of Head and Neck
Unknown
HPPH
×
Maximum Phase:
2
First Approval:
None
UNII:
DOB7Y3RSX0
Molecule Type:
Small molecule
Molecular Formula:
C39H48N4O4
Molecular Weight:
636.84
AlogP:
9.42
PSA:
120.96
HBD:
3.0
HBA:
#RotB:
11.0
Source:
MK-0457
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MK-0457
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
THR-18
2
Unknown
Investigational
Unknown
Unknown
Ischemic Stroke; Stroke
Unknown
THR-18
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GAMMA-TOCOPHEROL
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Inflammation
Unknown
GAMMA-TOCOPHEROL
×
Maximum Phase:
2
First Approval:
None
UNII:
8EF1Z1238F
Molecule Type:
Small molecule
Molecular Formula:
C28H48O2
Molecular Weight:
416.69
AlogP:
8.53
PSA:
29.46
HBD:
1.0
HBA:
#RotB:
12.0
Source:
TOZORAKIMAB
2
Antibody
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive; Asthma; Bronchitis, Chronic; Dermatitis, Atopic; Diabetic Nephropathies
Unknown
TOZORAKIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DIANEXIN
2
Protein
Investigational
Unknown
Unknown
Unknown
Unknown
DIANEXIN
×
Maximum Phase:
2
First Approval:
None
UNII:
S5HS95L6CN
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SERABELISIB
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Neoplasms; Carcinoma, Renal Cell; Endometrial Neoplasms
PI3-kinase p110-alpha subunit inhibitor
SERABELISIB
×
Maximum Phase:
2
First Approval:
None
UNII:
43J9Q56T3W
Molecule Type:
Small molecule
Molecular Formula:
C19H17N5O3
Molecular Weight:
363.38
AlogP:
2.2
PSA:
98.89
HBD:
1.0
HBA:
#RotB:
2.0
Source:
KRP203
2
Small molecule
Investigational
Unknown
Unknown
Hematologic Neoplasms; Colitis, Ulcerative; Lupus Erythematosus, Cutaneous
Sphingosine 1-phosphate receptor Edg-1 agonist
KRP203
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RAZUPENEM
2
Small molecule
Investigational
Unknown
Unknown
Infections
Bacterial penicillin-binding protein inhibitor
RAZUPENEM
×
Maximum Phase:
2
First Approval:
None
UNII:
26020H3Q1L
Molecule Type:
Small molecule
Molecular Formula:
C18H21N3O4S2
Molecular Weight:
407.52
AlogP:
1.76
PSA:
102.76
HBD:
3.0
HBA:
#RotB:
5.0
Source:
AZOXIMER BROMIDE
2
Small molecule
Investigational
Unknown
Unknown
Severe Acute Respiratory Syndrome
Unknown
AZOXIMER BROMIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
90G53638ZD
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PIMONIDAZOLE
2
Small molecule
Investigational
Unknown
Unknown
Rectal Neoplasms; Aortic Aneurysm, Thoracic; Prostatic Neoplasms, Castration-Resistant; Tuberculosis, Pulmonary
Unknown
PIMONIDAZOLE
×
Maximum Phase:
2
First Approval:
None
UNII:
46JO4D76R2
Molecule Type:
Small molecule
Molecular Formula:
C11H18N4O3
Molecular Weight:
254.29
AlogP:
0.64
PSA:
84.43
HBD:
1.0
HBA:
#RotB:
5.0
Source:
ACLIMOSTAT
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Methionine aminopeptidase 2 inhibitor
ACLIMOSTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
X150A3JK8R
Molecule Type:
Small molecule
Molecular Formula:
C26H42N2O6
Molecular Weight:
478.63
AlogP:
2.85
PSA:
76.3
HBD:
0.0
HBA:
#RotB:
8.0
Source:
RAFABEGRON
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Beta-3 adrenergic receptor agonist
RAFABEGRON
×
Maximum Phase:
2
First Approval:
None
UNII:
LN3E1Q0SU2
Molecule Type:
Small molecule
Molecular Formula:
C21H23ClN2O4
Molecular Weight:
402.88
AlogP:
3.54
PSA:
94.58
HBD:
4.0
HBA:
#RotB:
9.0
Source:
ORILOTIMOD
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ORILOTIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
Q66Z43C5XM
Molecule Type:
Small molecule
Molecular Formula:
C16H19N3O5
Molecular Weight:
333.34
AlogP:
0.47
PSA:
145.51
HBD:
5.0
HBA:
#RotB:
8.0
Source:
TU-100
2
Small molecule
Investigational
Unknown
Unknown
Constipation; Crohn Disease; Ileus; Irritable Bowel Syndrome
Unknown
TU-100
×
Maximum Phase:
2
First Approval:
None
UNII:
N3KQ8A1E0X
Molecule Type:
Small molecule
Molecular Formula:
C20H13NO3
Molecular Weight:
315.33
AlogP:
2.61
PSA:
54.45
HBD:
0.0
HBA:
#RotB:
0.0
Source:
INSM-18
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Insulin-like growth factor I receptor inhibitor
INSM-18
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CIRAPARANTAG
2
Small molecule
Investigational
Unknown
Unknown
Venous Thromboembolism
Apixaban sequestering agent
CIRAPARANTAG
×
Maximum Phase:
2
First Approval:
None
UNII:
U2R67KV65Q
Molecule Type:
Small molecule
Molecular Formula:
C22H48N12O2
Molecular Weight:
512.71
AlogP:
-3.2
PSA:
240.52
HBD:
10.0
HBA:
#RotB:
18.0
Source:
PHOSPHATIDYL SERINE
2
Small molecule
Investigational
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity
Unknown
PHOSPHATIDYL SERINE
×
Maximum Phase:
2
First Approval:
None
UNII:
394XK0IH40
Molecule Type:
Small molecule
Molecular Formula:
C42H82NO10P
Molecular Weight:
792.09
AlogP:
11.51
PSA:
171.68
HBD:
3.0
HBA:
#RotB:
42.0
Source:
PF-5190457
2
Small molecule
Investigational
Unknown
Unknown
Alcohol Drinking; Diabetes Mellitus, Type 2; Alcoholism
Ghrelin receptor inverse agonist
PF-5190457
×
Maximum Phase:
2
First Approval:
None
UNII:
FF33NL9U5G
Molecule Type:
Small molecule
Molecular Formula:
C29H32N6OS
Molecular Weight:
512.68
AlogP:
4.62
PSA:
66.63
HBD:
0.0
HBA:
#RotB:
4.0
Source:
POZIOTINIB
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Stomach Neoplasms; Adenocarcinoma of Lung; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Head and Neck Neoplasms
Epidermal growth factor receptor inhibitor
POZIOTINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
OEI6OOU6IK
Molecule Type:
Small molecule
Molecular Formula:
C23H21Cl2FN4O3
Molecular Weight:
491.35
AlogP:
5.38
PSA:
76.58
HBD:
1.0
HBA:
#RotB:
6.0
Source:
FASITIBANT
2
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis; Osteoarthritis, Knee
Unknown
FASITIBANT
×
Maximum Phase:
2
First Approval:
None
UNII:
0WL827Z7AE
Molecule Type:
Small molecule
Molecular Formula:
C36H49Cl2N6O6S+
Molecular Weight:
764.8
AlogP:
4.05
PSA:
144.16
HBD:
2.0
HBA:
#RotB:
12.0
Source:
AMITIFADINE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Monoamine transporter inhibitor
AMITIFADINE
×
Maximum Phase:
2
First Approval:
None
UNII:
GE0J375F8F
Molecule Type:
Small molecule
Molecular Formula:
C11H11Cl2N
Molecular Weight:
228.12
AlogP:
2.85
PSA:
12.03
HBD:
1.0
HBA:
#RotB:
1.0
Source:
PEPTIDE YY HUMAN (3-36)
2
Protein
Investigational
Unknown
Unknown
Feeding and Eating Disorders; Obesity
Unknown
PEPTIDE YY HUMAN (3-36)
×
Maximum Phase:
2
First Approval:
None
UNII:
7PQZ90ULIR
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
JNJ-17216498
2
Small molecule
Investigational
Unknown
Unknown
Narcolepsy
Histamine H3 receptor antagonist
JNJ-17216498
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INARIGIVIR
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
INARIGIVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
TQ0A9FIV71
Molecule Type:
Small molecule
Molecular Formula:
C20H26N7O10PS
Molecular Weight:
587.51
AlogP:
-1.05
PSA:
228.16
HBD:
5.0
HBA:
#RotB:
9.0
Source:
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Compound Structure
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Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA