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Therapeutic Area
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
BECOCALCIDIOL
2
Small molecule
Investigational
Unknown
Unknown
Psoriasis
Vitamin D receptor agonist
BECOCALCIDIOL
×
Maximum Phase:
2
First Approval:
None
UNII:
N75R59YD0F
Molecule Type:
Small molecule
Molecular Formula:
C23H36O2
Molecular Weight:
344.54
AlogP:
5.17
PSA:
40.46
HBD:
2.0
HBA:
#RotB:
3.0
Source:
HDI
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
HDI
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
APD371
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
APD371
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ACORAFLOXACIN HYDROCHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Infections; Pneumonia, Bacterial
Unknown
ACORAFLOXACIN HYDROCHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
1NWW5SKQ0N
Molecule Type:
Small molecule
Molecular Formula:
C21H24ClF2N3O4
Molecular Weight:
455.89
AlogP:
2.96
PSA:
97.79
HBD:
2.0
HBA:
#RotB:
5.0
Source:
TREGALIZUMAB
2
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Psoriasis
T-cell surface antigen CD4 agonist
TREGALIZUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
43D26MK176
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK2982772
2
Small molecule
Investigational
Unknown
Unknown
Immune System Diseases; Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Colitis, Ulcerative; Psoriasis
Unknown
GSK2982772
×
Maximum Phase:
2
First Approval:
None
UNII:
T5W3M0VO9B
Molecule Type:
Small molecule
Molecular Formula:
C20H19N5O3
Molecular Weight:
377.4
AlogP:
1.55
PSA:
100.21
HBD:
2.0
HBA:
#RotB:
4.0
Source:
PF-04457845
2
Small molecule
Investigational
Unknown
Unknown
Chronic Pain; Tourette Syndrome; Marijuana Abuse; Osteoarthritis, Knee; Stress Disorders, Post-Traumatic
Anandamide amidohydrolase inhibitor
PF-04457845
×
Maximum Phase:
2
First Approval:
None
UNII:
H4C81M8YYW
Molecule Type:
Small molecule
Molecular Formula:
C23H20F3N5O2
Molecular Weight:
455.44
AlogP:
5.39
PSA:
80.24
HBD:
1.0
HBA:
#RotB:
4.0
Source:
TENELIXIMAB
2
Antibody
Investigational
Unknown
Unknown
Unknown
Tumor necrosis factor receptor superfamily member 5 partial agonist
TENELIXIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
G0MV33WQ6V
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ECROMEXIMAB
2
Antibody
Investigational
Unknown
Unknown
Melanoma
Ganglioside GD3 other
ECROMEXIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
M76FX2JZRM
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ADL-5859
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Osteoarthritis, Knee; Pain
Unknown
ADL-5859
×
Maximum Phase:
2
First Approval:
None
UNII:
FA554TW3UP
Molecule Type:
Small molecule
Molecular Formula:
C24H28N2O3
Molecular Weight:
392.5
AlogP:
3.82
PSA:
61.8
HBD:
2.0
HBA:
#RotB:
4.0
Source:
MAVRILIMUMAB
2
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Giant Cell Arteritis; Severe Acute Respiratory Syndrome
Granulocyte-macrophage colony-stimulating factor receptor antagonist
MAVRILIMUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
1158JD1P9A
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NOX-100
2
Small molecule
Investigational
Unknown
Unknown
Hypotension
Unknown
NOX-100
×
Maximum Phase:
2
First Approval:
None
UNII:
7WFB66H4LB
Molecule Type:
Small molecule
Molecular Formula:
C8H17NO5S2
Molecular Weight:
271.36
AlogP:
-2.43
PSA:
104.39
HBD:
6.0
HBA:
#RotB:
6.0
Source:
PF-06882961
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PF-06882961
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TRIPLATIN TETRANITRATE
2
Small molecule
Investigational
Unknown
Unknown
Lung Neoplasms; Pancreatic Neoplasms
Unknown
TRIPLATIN TETRANITRATE
×
Maximum Phase:
2
First Approval:
None
UNII:
HAJ1000ARC
Molecule Type:
Small molecule
Molecular Formula:
C12H50Cl2N14O12Pt3
Molecular Weight:
1238.76
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
EFATUTAZONE
2
Small molecule
Investigational
Unknown
Unknown
Multiple Myeloma; Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Liposarcoma; Thyroid Neoplasms
Unknown
EFATUTAZONE
×
Maximum Phase:
2
First Approval:
None
UNII:
M17ILL71MC
Molecule Type:
Small molecule
Molecular Formula:
C27H26N4O4S
Molecular Weight:
502.6
AlogP:
5.04
PSA:
108.47
HBD:
2.0
HBA:
#RotB:
7.0
Source:
AZD2207
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Cannabinoid CB1 receptor antagonist
AZD2207
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C22H22Cl2F2N4O3+2
Molecular Weight:
499.35
AlogP:
3.67
PSA:
89.35
HBD:
4.0
HBA:
#RotB:
8.0
Source:
AZD1386
2
Small molecule
Investigational
Unknown
Unknown
Chronic Pain; Neuralgia; Pain
Vanilloid receptor antagonist
AZD1386
×
Maximum Phase:
2
First Approval:
None
UNII:
210323T9CP
Molecule Type:
Small molecule
Molecular Formula:
C19H13ClF3N3O3
Molecular Weight:
423.78
AlogP:
3.25
PSA:
78.51
HBD:
2.0
HBA:
#RotB:
2.0
Source:
ONC-201
2
Small molecule
Investigational
Unknown
Unknown
Diffuse Intrinsic Pontine Glioma; Gliosarcoma; Leukemia; Multiple Myeloma; Neoplasms; Breast Neoplasms; Endometrial Neoplasms; Glioblastoma; Glioma; Neuroendocrine Tumors
Unknown
ONC-201
×
Maximum Phase:
2
First Approval:
None
UNII:
9U35A31JAI
Molecule Type:
Small molecule
Molecular Formula:
C24H26N4O
Molecular Weight:
386.5
AlogP:
3.17
PSA:
39.15
HBD:
0.0
HBA:
#RotB:
4.0
Source:
OXALOACETATE
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Amyotrophic Lateral Sclerosis; Myasthenia Gravis; Breast Carcinoma In Situ; Parkinson Disease
Unknown
OXALOACETATE
×
Maximum Phase:
2
First Approval:
None
UNII:
2F399MM81J
Molecule Type:
Small molecule
Molecular Formula:
C4H4O5
Molecular Weight:
132.07
AlogP:
-0.89
PSA:
91.67
HBD:
2.0
HBA:
#RotB:
3.0
Source:
AZD-8848
2
Small molecule
Investigational
Unknown
Unknown
Rhinitis, Allergic, Seasonal
Toll-like receptor 7 agonist
AZD-8848
×
Maximum Phase:
2
First Approval:
None
UNII:
322ZMR6920
Molecule Type:
Small molecule
Molecular Formula:
C29H43N7O5
Molecular Weight:
569.71
AlogP:
2.21
PSA:
140.83
HBD:
2.0
HBA:
#RotB:
16.0
Source:
CP-461
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Renal Cell; Crohn Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Melanoma; Prostatic Neoplasms, Castration-Resistant
Unknown
CP-461
×
Maximum Phase:
2
First Approval:
None
UNII:
68OJX9I7DT
Molecule Type:
Small molecule
Molecular Formula:
C25H22ClFN2O
Molecular Weight:
420.92
AlogP:
5.25
PSA:
41.99
HBD:
1.0
HBA:
#RotB:
5.0
Source:
SLX-4090
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2; Hyperlipidemias; Hyperlipoproteinemia Type I; Hypertriglyceridemia
Microsomal triglyceride transfer protein inhibitor
SLX-4090
×
Maximum Phase:
2
First Approval:
None
UNII:
F84YQX13FV
Molecule Type:
Small molecule
Molecular Formula:
C31H25F3N2O4
Molecular Weight:
546.55
AlogP:
7.19
PSA:
67.87
HBD:
1.0
HBA:
#RotB:
5.0
Source:
PF-06823859
2
Unknown
Investigational
Unknown
Unknown
Dermatomyositis
Interferon beta inhibitor
PF-06823859
×
Maximum Phase:
2
First Approval:
None
UNII:
K2Q0JXS9B4
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MDX-070
2
Antibody
Investigational
Unknown
Unknown
Unknown
Glutamate carboxypeptidase II other
MDX-070
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CURCUMINOIDS
2
Unknown
Investigational
Unknown
Unknown
Uveitis; Arthritis, Rheumatoid
Unknown
CURCUMINOIDS
×
Maximum Phase:
2
First Approval:
None
UNII:
R7T2XCO5ZU
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZ9773
2
Antibody
Investigational
Unknown
Unknown
Unknown
TNF-alpha inhibitor
AZ9773
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DOCUSATE
2
Small molecule
Investigational
Unknown
Unknown
Constipation; Gastroparesis
Surfactant laxative
DOCUSATE
×
Maximum Phase:
2
First Approval:
None
UNII:
M7P27195AG
Molecule Type:
Small molecule
Molecular Formula:
C20H38O7S
Molecular Weight:
422.58
AlogP:
4.15
PSA:
106.97
HBD:
1.0
HBA:
#RotB:
16.0
Source:
AG-13958
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Vascular endothelial growth factor receptor inhibitor
AG-13958
×
Maximum Phase:
2
First Approval:
None
UNII:
BK72RP7F7D
Molecule Type:
Small molecule
Molecular Formula:
C26H22FN7O
Molecular Weight:
467.51
AlogP:
5.31
PSA:
100.52
HBD:
3.0
HBA:
#RotB:
6.0
Source:
IMM-101
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
IMM-101
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CCX140
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CCX140
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RINUCUMAB
2
Antibody
Investigational
Unknown
Unknown
Macular Degeneration
Platelet-derived growth factor receptor beta inhibitor
RINUCUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
10E3O6YI4W
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FORODESINE HYDROCHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Lymphoid; Lymphoma; Lymphoma, T-Cell, Peripheral; Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell
Purine nucleoside phosphorylase inhibitor
FORODESINE HYDROCHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
6SN82Y9U73
Molecule Type:
Small molecule
Molecular Formula:
C11H15ClN4O4
Molecular Weight:
302.72
AlogP:
-2.02
PSA:
134.26
HBD:
6.0
HBA:
#RotB:
2.0
Source:
[18F]D
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
[18F]D
×
Maximum Phase:
2
First Approval:
None
UNII:
Y1H4D2VKZD
Molecule Type:
Small molecule
Molecular Formula:
C22H27FN4O2
Molecular Weight:
398.48
AlogP:
3.77
PSA:
59.73
HBD:
0.0
HBA:
#RotB:
8.0
Source:
BMS-741672
2
Small molecule
Investigational
Unknown
Unknown
Neuralgia
C-C chemokine receptor type 2 antagonist
BMS-741672
×
Maximum Phase:
2
First Approval:
None
UNII:
3UAA36FHF1
Molecule Type:
Small molecule
Molecular Formula:
C24H33F3N6O3S
Molecular Weight:
542.63
AlogP:
2.84
PSA:
107.53
HBD:
2.0
HBA:
#RotB:
7.0
Source:
VUPANORSEN
2
Oligonucleotide
Investigational
Unknown
Unknown
Hyperlipoproteinemia Type II; Lipodystrophy, Familial Partial
Angiopoietin like 3 (ANGPTL3) mRNA antisense inhibitor
VUPANORSEN
×
Maximum Phase:
2
First Approval:
None
UNII:
A7YG62NHZ6
Molecule Type:
Oligonucleotide
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
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Molecular Formula
Molecular Weight
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PSA