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ENT (5)
EYE (23)
GASTROINTESTINAL (29)
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MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
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PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
CENOBAMATE
2020
Small molecule
Approved
Unknown
Unknown
Liver Diseases; Epilepsies, Partial; Epilepsy; Seizures
GABA-A receptor; anion channel positive allosteric modulator
CENOBAMATE
×
Maximum Phase:
4
First Approval:
2020
UNII:
P85X70RZWS
Molecule Type:
Small molecule
Molecular Formula:
C10H10ClN5O2
Molecular Weight:
267.68
AlogP:
1.16
PSA:
95.92
HBD:
1.0
HBA:
#RotB:
4.0
Source:
RIPRETINIB
2020
Small molecule
Approved
Unknown
Unknown
Gastrointestinal Stromal Tumors; Neoplasms
Platelet-derived growth factor receptor alpha inhibitor
RIPRETINIB
×
Maximum Phase:
4
First Approval:
2020
UNII:
9XW757O13D
Molecule Type:
Small molecule
Molecular Formula:
C24H21BrFN5O2
Molecular Weight:
510.37
AlogP:
5.67
PSA:
88.05
HBD:
3.0
HBA:
#RotB:
5.0
Source:
BEMPEDOIC ACID; EZETIMIBE
2020
Combination
Approved
Unknown
Unknown
Unknown
Unknown
BEMPEDOIC ACID; EZETIMIBE
×
Maximum Phase:
4
First Approval:
2020
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SELPERCATINIB
2020
Small molecule
Unknown
Unknown
Unknown
Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms
Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET inhibitor
SELPERCATINIB
×
Maximum Phase:
4
First Approval:
2020
UNII:
CEGM9YBNGD
Molecule Type:
Small molecule
Molecular Formula:
C29H31N7O3
Molecular Weight:
525.61
AlogP:
3.28
PSA:
112.04
HBD:
1.0
HBA:
#RotB:
8.0
Source:
MARIBAVIR
2021
Small molecule
approved
Unknown
Unknown
Cytomegalovirus Infections; Virus Diseases
Phosphotransferase pUL97 inhibitor
MARIBAVIR
×
Maximum Phase:
4
First Approval:
2021
UNII:
PTB4X93HE1
Molecule Type:
Small molecule
Molecular Formula:
C15H19Cl2N3O4
Molecular Weight:
376.24
AlogP:
1.77
PSA:
99.77
HBD:
4.0
HBA:
#RotB:
4.0
Source:
IBREXAFUNGERP
2021
Small molecule
Unknown
Unknown
Unknown
Mycoses; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Blastomycosis; Candidemia; Candidiasis, Invasive; Candidiasis, Vulvovaginal; Coccidioidomycosis; Histoplasmosis; Vulvovaginitis
1,3-beta-glucan synthase inhibitor
IBREXAFUNGERP
×
Maximum Phase:
4
First Approval:
2021
UNII:
A92JFM5XNU
Molecule Type:
Small molecule
Molecular Formula:
C44H67N5O4
Molecular Weight:
730.05
AlogP:
8.62
PSA:
125.38
HBD:
2.0
HBA:
#RotB:
8.0
Source:
CABOTEGRAVIR; RILPIVIRINE
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
CABOTEGRAVIR; RILPIVIRINE
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CELECOXIB; TRAMADOL HYDROCHLORIDE
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
CELECOXIB; TRAMADOL HYDROCHLORIDE
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VILOXAZINE HYDROCHLORIDE
2021
Small molecule
Unknown
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity
Norepinephrine transporter inhibitor
VILOXAZINE HYDROCHLORIDE
×
Maximum Phase:
4
First Approval:
2021
UNII:
OQW30I1332
Molecule Type:
Small molecule
Molecular Formula:
C13H20ClNO3
Molecular Weight:
273.76
AlogP:
1.45
PSA:
39.72
HBD:
1.0
HBA:
#RotB:
5.0
Source:
FOSDENOPTERIN HYDROBROMIDE
2021
Small molecule
Unknown
Unknown
Unknown
Metal Metabolism, Inborn Errors
Unknown
FOSDENOPTERIN HYDROBROMIDE
×
Maximum Phase:
4
First Approval:
2021
UNII:
X41B5W735T
Molecule Type:
Small molecule
Molecular Formula:
C10H19BrN5O10P
Molecular Weight:
480.17
AlogP:
-2.52
PSA:
201.28
HBD:
7.0
HBA:
#RotB:
0.0
Source:
FINASTERIDE; TADALAFIL
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
FINASTERIDE; TADALAFIL
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VERICIGUAT
2021
Small molecule
Approved
Unknown
Unknown
Coronary Disease; Cardiovascular Diseases; Heart Failure
Soluble guanylate cyclase activator
VERICIGUAT
×
Maximum Phase:
4
First Approval:
2021
UNII:
LV66ADM269
Molecule Type:
Small molecule
Molecular Formula:
C19H16F2N8O2
Molecular Weight:
426.39
AlogP:
2.56
PSA:
146.86
HBD:
3.0
HBA:
#RotB:
4.0
Source:
PONESIMOD
2021
Small molecule
Approved
Unknown
Unknown
Graft vs Host Disease; Psoriasis; Multiple Sclerosis
Sphingosine 1-phosphate receptor Edg-1 agonist
PONESIMOD
×
Maximum Phase:
4
First Approval:
2021
UNII:
5G7AKV2MKP
Molecule Type:
Small molecule
Molecular Formula:
C23H25ClN2O4S
Molecular Weight:
460.98
AlogP:
4.27
PSA:
82.36
HBD:
2.0
HBA:
#RotB:
8.0
Source:
BELUMOSUDIL MESYLATE
2021
Small molecule
Unknown
Unknown
Unknown
Graft vs Host Disease
Rho-associated protein kinase inhibitor
BELUMOSUDIL MESYLATE
×
Maximum Phase:
4
First Approval:
2021
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C27H28N6O5S
Molecular Weight:
548.63
AlogP:
4.82
PSA:
104.82
HBD:
3.0
HBA:
#RotB:
7.0
Source:
MOBOCERTINIB
2021
Small molecule
Unknown
Unknown
Unknown
Kidney Diseases; Liver Diseases; Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
MOBOCERTINIB
×
Maximum Phase:
4
First Approval:
2021
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C32H39N7O4
Molecular Weight:
585.71
AlogP:
5.08
PSA:
113.85
HBD:
2.0
HBA:
#RotB:
12.0
Source:
ODEVIXIBAT
2021
Small molecule
Approved
Unknown
Unknown
Cholestasis; Liver Cirrhosis, Biliary; Non-alcoholic Fatty Liver Disease; Alagille Syndrome; Biliary Atresia; Cholestasis, Intrahepatic; Pruritus
Ileal bile acid transporter inhibitor
ODEVIXIBAT
×
Maximum Phase:
4
First Approval:
2021
UNII:
2W150K0UUC
Molecule Type:
Small molecule
Molecular Formula:
C37H48N4O8S2
Molecular Weight:
740.95
AlogP:
5.88
PSA:
174.37
HBD:
5.0
HBA:
#RotB:
17.0
Source:
ATOGEPANT
2021
Small molecule
Approved
Unknown
Unknown
Migraine Disorders
Calcitonin gene-related peptide type 1 receptor antagonist
ATOGEPANT
×
Maximum Phase:
4
First Approval:
2021
UNII:
7CRV8RR151
Molecule Type:
Small molecule
Molecular Formula:
C29H23F6N5O3
Molecular Weight:
603.52
AlogP:
3.95
PSA:
104.29
HBD:
2.0
HBA:
#RotB:
4.0
Source:
AMPHETAMINE ASPARTATE ; AMPHETAMINE SULFATE; DEXTROAMPHETAMINE SACCHARATE; DEXTROAMPHETAMINE SULFATE
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
AMPHETAMINE ASPARTATE ; AMPHETAMINE SULFATE; DEXTROAMPHETAMINE SACCHARATE; DEXTROAMPHETAMINE SULFATE
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLANZAPINE; SAMIDORPHAN L-MALATE
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
OLANZAPINE; SAMIDORPHAN L-MALATE
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BENZOYL PEROXIDE; TRETINOIN
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
BENZOYL PEROXIDE; TRETINOIN
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BELZUTIFAN
2021
Small molecule
Approved
Unknown
Unknown
Carcinoma, Renal Cell; Hemangioblastoma; Neuroendocrine Tumors; von Hippel-Lindau Disease
Endothelial PAS domain-containing protein 1 inhibitor
BELZUTIFAN
×
Maximum Phase:
4
First Approval:
2021
UNII:
7K28NB895L
Molecule Type:
Small molecule
Molecular Formula:
C17H12F3NO4S
Molecular Weight:
383.35
AlogP:
3.29
PSA:
87.39
HBD:
1.0
HBA:
#RotB:
3.0
Source:
ESTRADIOL; NORETHINDRONE ACETATE; RELUGOLIX
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
ESTRADIOL; NORETHINDRONE ACETATE; RELUGOLIX
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
UMBRALISIB
2021
Small molecule
Approved
Unknown
Unknown
Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia
Unknown
UMBRALISIB
×
Maximum Phase:
4
First Approval:
2021
UNII:
38073MQB2A
Molecule Type:
Small molecule
Molecular Formula:
C31H24F3N5O3
Molecular Weight:
571.56
AlogP:
6.66
PSA:
109.06
HBD:
1.0
HBA:
#RotB:
6.0
Source:
INFIGRATINIB PHOSPHATE
2021
Small molecule
Unknown
Unknown
Unknown
Cholangiocarcinoma
Fibroblast growth factor receptor inhibitor
INFIGRATINIB PHOSPHATE
×
Maximum Phase:
4
First Approval:
2021
UNII:
58BH47BV6S
Molecule Type:
Small molecule
Molecular Formula:
C26H34Cl2N7O7P
Molecular Weight:
658.48
AlogP:
5.35
PSA:
95.09
HBD:
2.0
HBA:
#RotB:
8.0
Source:
DASIGLUCAGON HYDROCHLORIDE
2021
Unknown
Unknown
Unknown
Unknown
Diabetes Mellitus, Type 1; Hypoglycemia
Glucagon receptor agonist
DASIGLUCAGON HYDROCHLORIDE
×
Maximum Phase:
4
First Approval:
2021
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PEGCETACOPLAN
2021
Protein
Approved
Unknown
Unknown
Amyotrophic Lateral Sclerosis; Glomerulonephritis, Membranoproliferative; Macular Degeneration; Hemoglobinuria, Paroxysmal
Complement C3 inhibitor
PEGCETACOPLAN
×
Maximum Phase:
4
First Approval:
2021
UNII:
TO3JYR3BOU
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VOSORITIDE
2021
Protein
Investigational
Unknown
Unknown
Achondroplasia
Atrial natriuretic peptide receptor B binding agent
VOSORITIDE
×
Maximum Phase:
4
First Approval:
2021
UNII:
7SE5582Q2P
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DROSPIRENONE; ESTETROL
2021
Combination
Approved
Unknown
Unknown
Unknown
Unknown
DROSPIRENONE; ESTETROL
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Combination
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VILOXAZINE
2021
Small molecule
Approved
Unknown
Unknown
Depressive Disorder
Unknown
VILOXAZINE
×
Maximum Phase:
4
First Approval:
2021
UNII:
5I5Y2789ZF
Molecule Type:
Small molecule
Molecular Formula:
C13H19NO3
Molecular Weight:
237.3
AlogP:
1.45
PSA:
39.72
HBD:
1.0
HBA:
#RotB:
5.0
Source:
PIFLUFOLASTAT F18
2021
Small molecule
Unknown
Unknown
Unknown
Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Diagnostic agent
PIFLUFOLASTAT F18
×
Maximum Phase:
4
First Approval:
2021
UNII:
3934EF02T7
Molecule Type:
Small molecule
Molecular Formula:
C18H23FN4O8
Molecular Weight:
441.4
AlogP:
0.19
PSA:
195.02
HBD:
6.0
HBA:
#RotB:
13.0
Source:
INCLISIRAN SODIUM
2021
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
INCLISIRAN SODIUM
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CASIMERSEN
2021
Oligonucleotide
Approved
Unknown
Unknown
Muscular Dystrophies; Muscular Dystrophy, Duchenne
Dystrophin pre-mRNA positive modulator
CASIMERSEN
×
Maximum Phase:
4
First Approval:
2021
UNII:
X8UHF7SX0R
Molecule Type:
Oligonucleotide
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ASCIMINIB HYDROCHLORIDE
2021
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
ASCIMINIB HYDROCHLORIDE
×
Maximum Phase:
4
First Approval:
2021
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SERDEXMETHYLPHENIDATE
2021
Small molecule
Unknown
Unknown
Unknown
Unknown
Unknown
SERDEXMETHYLPHENIDATE
×
Maximum Phase:
4
First Approval:
2021
UNII:
0H8KZ470DW
Molecule Type:
Small molecule
Molecular Formula:
C25H30N3O8+
Molecular Weight:
500.53
AlogP:
1.05
PSA:
146.35
HBD:
3.0
HBA:
#RotB:
9.0
Source:
FOSDENOPTERIN
2021
Small molecule
Unknown
Unknown
Unknown
Unknown
Unknown
FOSDENOPTERIN
×
Maximum Phase:
4
First Approval:
2021
UNII:
4X7K2681Y7
Molecule Type:
Small molecule
Molecular Formula:
C10H14N5O8P
Molecular Weight:
363.22
AlogP:
-2.52
PSA:
201.28
HBD:
7.0
HBA:
#RotB:
0.0
Source:
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Compound Name
Maximum Phase
Compound Structure
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Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA