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EMERGENCY MEDICINE (3)
ENT (5)
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GASTROINTESTINAL (29)
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MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
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PHARMACOLOGY (8)
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RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
ZONAMPANEL
2
Small molecule
Investigational
Unknown
Unknown
Ischemic Stroke; Stroke
Glutamate receptor ionotropic AMPA antagonist
ZONAMPANEL
×
Maximum Phase:
2
First Approval:
None
UNII:
9X33544ILS
Molecule Type:
Small molecule
Molecular Formula:
C13H9N5O6
Molecular Weight:
331.24
AlogP:
-0.13
PSA:
153.12
HBD:
2.0
HBA:
#RotB:
4.0
Source:
AZD7986
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AZD7986
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-986141
2
Small molecule
Investigational
Unknown
Unknown
Ischemic Stroke; Liver Diseases; Thrombosis
Proteinase activated receptor 4 antagonist
BMS-986141
×
Maximum Phase:
2
First Approval:
None
UNII:
W530IRZ40G
Molecule Type:
Small molecule
Molecular Formula:
C27H23N5O5S2
Molecular Weight:
561.65
AlogP:
5.63
PSA:
104.22
HBD:
0.0
HBA:
#RotB:
8.0
Source:
TOCOTRIENOL
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Colorectal Neoplasms; Ovarian Neoplasms; Ischemic Stroke
Unknown
TOCOTRIENOL
×
Maximum Phase:
2
First Approval:
None
UNII:
0867I0N41V
Molecule Type:
Small molecule
Molecular Formula:
C26H38O2
Molecular Weight:
382.59
AlogP:
7.68
PSA:
29.46
HBD:
1.0
HBA:
#RotB:
9.0
Source:
BMS-690514
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
BMS-690514
×
Maximum Phase:
2
First Approval:
None
UNII:
VKU5X213Q7
Molecule Type:
Small molecule
Molecular Formula:
C19H24N6O2
Molecular Weight:
368.44
AlogP:
1.38
PSA:
100.94
HBD:
3.0
HBA:
#RotB:
5.0
Source:
LY2801653
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LY2801653
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SEPANTRONIUM
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SEPANTRONIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
UZ77T1VFBM
Molecule Type:
Small molecule
Molecular Formula:
C20H19N4O3+
Molecular Weight:
363.4
AlogP:
1.34
PSA:
77.96
HBD:
0.0
HBA:
#RotB:
5.0
Source:
OLVEREMBATINIB
2
Small molecule
Investigational
Unknown
Unknown
Gastrointestinal Stromal Tumors; Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Bcr/Abl fusion protein inhibitor
OLVEREMBATINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
KV1M7Q3CBP
Molecule Type:
Small molecule
Molecular Formula:
C29H27F3N6O
Molecular Weight:
532.57
AlogP:
4.68
PSA:
77.15
HBD:
2.0
HBA:
#RotB:
4.0
Source:
EDICOTINIB
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms; Arthritis, Rheumatoid; Leukemia, Myeloid, Acute
Macrophage colony stimulating factor receptor inhibitor
EDICOTINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
3NU609VYNF
Molecule Type:
Small molecule
Molecular Formula:
C27H35N5O2
Molecular Weight:
461.61
AlogP:
5.97
PSA:
103.69
HBD:
2.0
HBA:
#RotB:
4.0
Source:
CH-1504 L-ISOMER
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid
Unknown
CH-1504 L-ISOMER
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C23H23N5O5
Molecular Weight:
449.47
AlogP:
1.79
PSA:
181.52
HBD:
5.0
HBA:
#RotB:
9.0
Source:
SODIUM ACID PYROPHOSPHATE
2
Small molecule
Investigational
Unknown
Unknown
Pseudoxanthoma Elasticum
Unknown
SODIUM ACID PYROPHOSPHATE
×
Maximum Phase:
2
First Approval:
None
UNII:
H5WVD9LZUD
Molecule Type:
Small molecule
Molecular Formula:
H2Na2O7P2
Molecular Weight:
221.94
AlogP:
-0.81
PSA:
124.29
HBD:
4.0
HBA:
#RotB:
2.0
Source:
SR16234
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms
Estrogen receptor alpha antagonist
SR16234
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C33H47NO3
Molecular Weight:
505.74
AlogP:
7.43
PSA:
41.93
HBD:
1.0
HBA:
#RotB:
9.0
Source:
ORILOTIMOD POTASSIUM
2
Small molecule
Investigational
Unknown
Unknown
Psoriasis
Unknown
ORILOTIMOD POTASSIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
Q8858ZSK4Y
Molecule Type:
Small molecule
Molecular Formula:
C16H18KN3O5
Molecular Weight:
371.43
AlogP:
0.47
PSA:
145.51
HBD:
5.0
HBA:
#RotB:
8.0
Source:
MOLIBRESIB
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma; Neoplasms
Bromodomain and extra-terminal motif (BET) inhibitor
MOLIBRESIB
×
Maximum Phase:
2
First Approval:
None
UNII:
5QIO6SRZ2R
Molecule Type:
Small molecule
Molecular Formula:
C22H22ClN5O2
Molecular Weight:
423.9
AlogP:
3.66
PSA:
81.4
HBD:
1.0
HBA:
#RotB:
5.0
Source:
GANDOTINIB
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Tyrosine-protein kinase JAK2 inhibitor
GANDOTINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
ANC71R916O
Molecule Type:
Small molecule
Molecular Formula:
C23H25ClFN7O
Molecular Weight:
469.95
AlogP:
4.03
PSA:
83.37
HBD:
2.0
HBA:
#RotB:
6.0
Source:
DONITRIPTAN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
G protein-coupled receptor 44 antagonist
DONITRIPTAN
×
Maximum Phase:
2
First Approval:
None
UNII:
70968BVH2J
Molecule Type:
Small molecule
Molecular Formula:
C23H25N5O2
Molecular Weight:
403.49
AlogP:
2.27
PSA:
98.38
HBD:
2.0
HBA:
#RotB:
6.0
Source:
POLAPREZINC
2
Small molecule
Investigational
Unknown
Unknown
Peripheral Arterial Disease; Persian Gulf Syndrome; Schizophrenia
Unknown
POLAPREZINC
×
Maximum Phase:
2
First Approval:
None
UNII:
8HO6PVN24W
Molecule Type:
Small molecule
Molecular Formula:
C9H14N4O3
Molecular Weight:
226.24
AlogP:
-1.13
PSA:
121.1
HBD:
4.0
HBA:
#RotB:
6.0
Source:
JNJ-40411813
2
Small molecule
Investigational
Unknown
Unknown
Perceptual Disorders; Depressive Disorder, Major; Schizophrenia; Seizures
Metabotropic glutamate receptor 2 positive allosteric modulator
JNJ-40411813
×
Maximum Phase:
2
First Approval:
None
UNII:
612BYT76F3
Molecule Type:
Small molecule
Molecular Formula:
C20H25ClN2O
Molecular Weight:
344.89
AlogP:
4.69
PSA:
25.24
HBD:
0.0
HBA:
#RotB:
5.0
Source:
PRITELIVIR
2
Small molecule
Investigational
Unknown
Unknown
Herpes Genitalis; Herpes Labialis; Infections
Helicase/primase inhibitor
PRITELIVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
07HQ1TJ4JE
Molecule Type:
Small molecule
Molecular Formula:
C18H18N4O3S2
Molecular Weight:
402.5
AlogP:
2.37
PSA:
106.25
HBD:
1.0
HBA:
#RotB:
5.0
Source:
ALBITIAZOLIUM
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ALBITIAZOLIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
HKM715W3UT
Molecule Type:
Small molecule
Molecular Formula:
C24H42N2O2S2+2
Molecular Weight:
454.75
AlogP:
4.67
PSA:
48.22
HBD:
2.0
HBA:
#RotB:
17.0
Source:
NERISPIRDINE
2
Small molecule
Investigational
Unknown
Unknown
Multiple Sclerosis; Spinal Cord Injuries
Sodium channel alpha subunit blocker
NERISPIRDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
G7M7YWO6CG
Molecule Type:
Small molecule
Molecular Formula:
C17H18FN3
Molecular Weight:
283.35
AlogP:
4.16
PSA:
21.06
HBD:
0.0
HBA:
#RotB:
4.0
Source:
N-ACETYLMANNOSAMINE
2
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases
Unknown
N-ACETYLMANNOSAMINE
×
Maximum Phase:
2
First Approval:
None
UNII:
A1O5EUP7KS
Molecule Type:
Small molecule
Molecular Formula:
C8H15NO6
Molecular Weight:
221.21
AlogP:
-3.08
PSA:
119.25
HBD:
5.0
HBA:
#RotB:
2.0
Source:
ONVANSERTIB
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Neoplasms; Carcinoma, Pancreatic Ductal; Prostatic Neoplasms, Castration-Resistant
Serine/threonine-protein kinase PLK1 inhibitor
ONVANSERTIB
×
Maximum Phase:
2
First Approval:
None
UNII:
67RM91WDHQ
Molecule Type:
Small molecule
Molecular Formula:
C24H27F3N8O3
Molecular Weight:
532.53
AlogP:
1.92
PSA:
134.66
HBD:
3.0
HBA:
#RotB:
7.0
Source:
NEOMYCIN
2
Small molecule
Investigational
Unknown
Unknown
Osteomyelitis; Neoplasms; Bacteremia; Crohn Disease; Pneumonia; Prediabetic State; Bacterial Infections; Eye Infections; Infections
Bacterial 70S ribosome inhibitor
NEOMYCIN
×
Maximum Phase:
2
First Approval:
None
UNII:
I16QD7X297
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HALOFUGINONE
2
Small molecule
Investigational
Unknown
Unknown
Muscular Dystrophy, Duchenne
Unknown
HALOFUGINONE
×
Maximum Phase:
2
First Approval:
None
UNII:
L31MM1385E
Molecule Type:
Small molecule
Molecular Formula:
C16H17BrClN3O3
Molecular Weight:
414.69
AlogP:
1.88
PSA:
84.22
HBD:
2.0
HBA:
#RotB:
4.0
Source:
EZLOPITANT
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Neurokinin 1 receptor antagonist
EZLOPITANT
×
Maximum Phase:
2
First Approval:
None
UNII:
3L098A8MPY
Molecule Type:
Small molecule
Molecular Formula:
C31H38N2O
Molecular Weight:
454.66
AlogP:
6.2
PSA:
24.5
HBD:
1.0
HBA:
#RotB:
8.0
Source:
SILIBININ
2
Small molecule
Investigational
Unknown
Unknown
Tobacco Use Disorder; Hepatitis C; Liver Failure; Prostatic Neoplasms, Castration-Resistant
Unknown
SILIBININ
×
Maximum Phase:
2
First Approval:
None
UNII:
4RKY41TBTF
Molecule Type:
Small molecule
Molecular Formula:
C25H22O10
Molecular Weight:
482.44
AlogP:
2.36
PSA:
155.14
HBD:
5.0
HBA:
#RotB:
4.0
Source:
ORG-25935
2
Small molecule
Investigational
Unknown
Unknown
Alcoholism; Panic Disorder; Schizophrenia
Glycine transporter 1 inhibitor
ORG-25935
×
Maximum Phase:
2
First Approval:
None
UNII:
55L20667O4
Molecule Type:
Small molecule
Molecular Formula:
C21H25NO3
Molecular Weight:
339.44
AlogP:
3.41
PSA:
49.77
HBD:
1.0
HBA:
#RotB:
6.0
Source:
KRT-232
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
KRT-232
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DARINAPARSIN
2
Small molecule
Investigational
Unknown
Unknown
Lymphoma; Neoplasms; Bone Marrow Neoplasms; Carcinoma, Hepatocellular; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Multiple Myeloma
Unknown
DARINAPARSIN
×
Maximum Phase:
2
First Approval:
None
UNII:
9XX54M675G
Molecule Type:
Small molecule
Molecular Formula:
C12H22AsN3O6S
Molecular Weight:
411.31
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
GIRIPLADIB
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Osteoarthritis
Cytosolic phospholipase A2 inhibitor
GIRIPLADIB
×
Maximum Phase:
2
First Approval:
None
UNII:
1W10Q5H7WD
Molecule Type:
Small molecule
Molecular Formula:
C41H36ClF3N2O4S
Molecular Weight:
745.26
AlogP:
9.49
PSA:
88.4
HBD:
2.0
HBA:
#RotB:
14.0
Source:
AMG-337
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Sarcoma, Clear Cell; Stomach Neoplasms
Hepatocyte growth factor receptor inhibitor
AMG-337
×
Maximum Phase:
2
First Approval:
None
UNII:
08WG8S0L8D
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
STRONTIUM
2
Small molecule
Investigational
Unknown
Unknown
Osteoporosis
Unknown
STRONTIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
YZS2RPE8LE
Molecule Type:
Small molecule
Molecular Formula:
H2Sr
Molecular Weight:
89.64
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
ISOXAFLUTOLE
2
Small molecule
Investigational
Unknown
Unknown
Herpes Labialis
Unknown
ISOXAFLUTOLE
×
Maximum Phase:
2
First Approval:
None
UNII:
0T9R0O0EYT
Molecule Type:
Small molecule
Molecular Formula:
C15H12F3NO4S
Molecular Weight:
359.33
AlogP:
3.21
PSA:
77.24
HBD:
0.0
HBA:
#RotB:
4.0
Source:
DIMIRACETAM
2
Small molecule
Investigational
Unknown
Unknown
Acquired Immunodeficiency Syndrome
Unknown
DIMIRACETAM
×
Maximum Phase:
2
First Approval:
None
UNII:
4AW7F70MZO
Molecule Type:
Small molecule
Molecular Formula:
C6H8N2O2
Molecular Weight:
140.14
AlogP:
-0.94
PSA:
49.41
HBD:
1.0
HBA:
#RotB:
0.0
Source:
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PSA