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Therapeutic Area
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EMERGENCY MEDICINE (3)
ENT (5)
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GASTROINTESTINAL (29)
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MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
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Mechanism of Action
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
DANUGLIPRON
2
Small molecule
Investigational
Unknown
Unknown
Liver Diseases; Diabetes Mellitus, Type 2; Obesity
Glucagon-like peptide 1 receptor agonist
DANUGLIPRON
×
Maximum Phase:
2
First Approval:
None
UNII:
DN9IUI24GP
Molecule Type:
Small molecule
Molecular Formula:
C31H30FN5O4
Molecular Weight:
555.61
AlogP:
4.89
PSA:
113.5
HBD:
1.0
HBA:
#RotB:
9.0
Source:
ARAMCHOL
2
Small molecule
Investigational
Unknown
Unknown
Liver Diseases; Fatty Liver; Gallstones; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease
Unknown
ARAMCHOL
×
Maximum Phase:
2
First Approval:
None
UNII:
QE1Q24M65Y
Molecule Type:
Small molecule
Molecular Formula:
C44H79NO5
Molecular Weight:
702.12
AlogP:
10.61
PSA:
106.86
HBD:
4.0
HBA:
#RotB:
23.0
Source:
QUINAGOLIDE
2
Small molecule
Investigational
Unknown
Unknown
Ovarian Hyperstimulation Syndrome
Dopamine D2 receptor agonist
QUINAGOLIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
80Q9QWN15M
Molecule Type:
Small molecule
Molecular Formula:
C20H33N3O3S
Molecular Weight:
395.57
AlogP:
2.14
PSA:
72.88
HBD:
2.0
HBA:
#RotB:
7.0
Source:
NEZULCITINIB
2
Small molecule
Investigational
Unknown
Unknown
Acute Lung Injury; Severe Acute Respiratory Syndrome
Unknown
NEZULCITINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C30H37N7O2
Molecular Weight:
527.67
AlogP:
3.8
PSA:
104.38
HBD:
3.0
HBA:
#RotB:
6.0
Source:
PLITIDEPSIN
2
Small molecule
Investigational
Unknown
Unknown
Liposarcoma; Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms, Castration-Resistant; Multiple Myeloma; Neoplasms; Severe Acute Respiratory Syndrome
Elongation factor 1-alpha 2 inhibitor
PLITIDEPSIN
×
Maximum Phase:
2
First Approval:
None
UNII:
Y76ID234HW
Molecule Type:
Small molecule
Molecular Formula:
C57H87N7O15
Molecular Weight:
1110.36
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
BGT-226
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Hamartoma Syndrome, Multiple; Neoplasms
PI3-kinase class I inhibitor
BGT-226
×
Maximum Phase:
2
First Approval:
None
UNII:
ZXE7F2GMJJ
Molecule Type:
Small molecule
Molecular Formula:
C28H25F3N6O2
Molecular Weight:
534.54
AlogP:
4.38
PSA:
77.21
HBD:
1.0
HBA:
#RotB:
4.0
Source:
GLYCERYL TRIOLEATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GLYCERYL TRIOLEATE
×
Maximum Phase:
2
First Approval:
None
UNII:
O05EC62663
Molecule Type:
Small molecule
Molecular Formula:
C57H104O6
Molecular Weight:
885.45
AlogP:
18.1
PSA:
78.9
HBD:
0.0
HBA:
#RotB:
50.0
Source:
SQUARIC ACID DIBUTYL ESTER
2
Small molecule
Investigational
Unknown
Unknown
Herpes Labialis
Unknown
SQUARIC ACID DIBUTYL ESTER
×
Maximum Phase:
2
First Approval:
None
UNII:
4RTO57VG65
Molecule Type:
Small molecule
Molecular Formula:
C12H18O4
Molecular Weight:
226.27
AlogP:
1.64
PSA:
52.6
HBD:
0.0
HBA:
#RotB:
8.0
Source:
POLYSTYRENE SULFONATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
POLYSTYRENE SULFONATE
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ORG-34517
2
Small molecule
Investigational
Unknown
Unknown
Alcoholism; Depressive Disorder; Depressive Disorder, Major
Glucocorticoid receptor antagonist
ORG-34517
×
Maximum Phase:
2
First Approval:
None
UNII:
17VAN37K4Y
Molecule Type:
Small molecule
Molecular Formula:
C28H30O4
Molecular Weight:
430.54
AlogP:
5.07
PSA:
55.76
HBD:
1.0
HBA:
#RotB:
1.0
Source:
EPETIRIMOD
2
Small molecule
Investigational
Unknown
Unknown
Papillomavirus Infections
Unknown
EPETIRIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
9P5MH9F521
Molecule Type:
Small molecule
Molecular Formula:
C13H15N5
Molecular Weight:
241.3
AlogP:
2.22
PSA:
69.62
HBD:
1.0
HBA:
#RotB:
2.0
Source:
INDANTADOL
2
Small molecule
Investigational
Unknown
Unknown
Cough; Diabetic Neuropathies; Neuralgia; Pain
Glutamate [NMDA] receptor antagonist
INDANTADOL
×
Maximum Phase:
2
First Approval:
None
UNII:
Z3867B9SQP
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IODOCARB
2
Small molecule
Investigational
Unknown
Unknown
Fatigue Syndrome, Chronic; Pulmonary Disease, Chronic Obstructive
Unknown
IODOCARB
×
Maximum Phase:
2
First Approval:
None
UNII:
603P14DHEB
Molecule Type:
Small molecule
Molecular Formula:
C8H12INO2
Molecular Weight:
281.09
AlogP:
1.91
PSA:
38.33
HBD:
1.0
HBA:
#RotB:
4.0
Source:
ENMD-2076
2
Small molecule
Investigational
Unknown
Unknown
Hematologic Neoplasms; Multiple Myeloma; Neoplasms; Adenocarcinoma, Clear Cell; Breast Neoplasms; Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Sarcoma
Fibroblast growth factor receptor 3 inhibitor
ENMD-2076
×
Maximum Phase:
2
First Approval:
None
UNII:
J6U9WP10T7
Molecule Type:
Small molecule
Molecular Formula:
C21H25N7
Molecular Weight:
375.48
AlogP:
3.17
PSA:
72.97
HBD:
2.0
HBA:
#RotB:
5.0
Source:
AR-67
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Gliosarcoma; Myelodysplastic Syndromes
Unknown
AR-67
×
Maximum Phase:
2
First Approval:
None
UNII:
3YEA04NV6H
Molecule Type:
Small molecule
Molecular Formula:
C26H30N2O5Si
Molecular Weight:
478.62
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
VELUSETRAG
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Gastroparesis
Serotonin 4 (5-HT4) receptor agonist
VELUSETRAG
×
Maximum Phase:
2
First Approval:
None
UNII:
J4VNV64ARB
Molecule Type:
Small molecule
Molecular Formula:
C25H36N4O5S
Molecular Weight:
504.65
AlogP:
1.56
PSA:
111.95
HBD:
2.0
HBA:
#RotB:
8.0
Source:
DE-112
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
DE-112
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DARIGABAT
2
Small molecule
Investigational
Unknown
Unknown
Panic Disorder; Anxiety Disorders; Epilepsy, Reflex; Low Back Pain; Seizures
GABA-A receptor; anion channel agonist
DARIGABAT
×
Maximum Phase:
2
First Approval:
None
UNII:
O9BP19HZ3Q
Molecule Type:
Small molecule
Molecular Formula:
C22H21FN4O3S
Molecular Weight:
440.5
AlogP:
4.12
PSA:
86.97
HBD:
0.0
HBA:
#RotB:
6.0
Source:
FLUZOPARIB
2
Small molecule
Investigational
Unknown
Unknown
Liver Diseases; Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Nasopharyngeal Neoplasms; Breast Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Unknown
FLUZOPARIB
×
Maximum Phase:
2
First Approval:
None
UNII:
TWF0ML1CK8
Molecule Type:
Small molecule
Molecular Formula:
C22H16F4N6O2
Molecular Weight:
472.4
AlogP:
2.92
PSA:
96.77
HBD:
1.0
HBA:
#RotB:
3.0
Source:
IRL790
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
IRL790
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GRAPIPRANT
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Osteoarthritis
Prostanoid EP4 receptor antagonist
GRAPIPRANT
×
Maximum Phase:
2
First Approval:
None
UNII:
J9F5ZPH7NB
Molecule Type:
Small molecule
Molecular Formula:
C26H29N5O3S
Molecular Weight:
491.62
AlogP:
4.14
PSA:
105.98
HBD:
2.0
HBA:
#RotB:
7.0
Source:
EVENAMIDE
2
Small molecule
Investigational
Unknown
Unknown
Schizophrenia
Sodium channel alpha subunit blocker
EVENAMIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
ON5S6N53JS
Molecule Type:
Small molecule
Molecular Formula:
C16H26N2O2
Molecular Weight:
278.4
AlogP:
2.09
PSA:
41.57
HBD:
1.0
HBA:
#RotB:
9.0
Source:
GS-0938
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GS-0938
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CHLOROPHENYLPIPERAZINE
2
Small molecule
Investigational
Unknown
Unknown
Alcoholism; Cocaine-Related Disorders
Unknown
CHLOROPHENYLPIPERAZINE
×
Maximum Phase:
2
First Approval:
None
UNII:
REY0CNO998
Molecule Type:
Small molecule
Molecular Formula:
C10H13ClN2
Molecular Weight:
196.68
AlogP:
1.75
PSA:
15.27
HBD:
1.0
HBA:
#RotB:
1.0
Source:
ARTEROLANE
2
Small molecule
Investigational
Unknown
Unknown
Malaria, Falciparum
Unknown
ARTEROLANE
×
Maximum Phase:
2
First Approval:
None
UNII:
3N1TN351VB
Molecule Type:
Small molecule
Molecular Formula:
C29H44N2O7S
Molecular Weight:
564.75
AlogP:
3.25
PSA:
82.81
HBD:
2.0
HBA:
#RotB:
4.0
Source:
REGRELOR
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
REGRELOR
×
Maximum Phase:
2
First Approval:
None
UNII:
Q6C8TY6SW1
Molecule Type:
Small molecule
Molecular Formula:
C22H25N6O8P
Molecular Weight:
532.45
AlogP:
1.8
PSA:
179.18
HBD:
4.0
HBA:
#RotB:
8.0
Source:
E-7090
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Liver Diseases; Cholangiocarcinoma; Neoplasms
Fibroblast growth factor receptor 1 inhibitor
E-7090
×
Maximum Phase:
2
First Approval:
None
UNII:
TN7CUD1NGA
Molecule Type:
Small molecule
Molecular Formula:
C32H37N5O6
Molecular Weight:
587.68
AlogP:
4.47
PSA:
127.18
HBD:
3.0
HBA:
#RotB:
11.0
Source:
TEMPOL
2
Small molecule
Investigational
Unknown
Unknown
Anus Neoplasms; Cardiovascular Diseases; Alopecia; Glioblastoma; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome
Unknown
TEMPOL
×
Maximum Phase:
2
First Approval:
None
UNII:
U78ZX2F65X
Molecule Type:
Small molecule
Molecular Formula:
C9H18NO2
Molecular Weight:
172.25
AlogP:
1.35
PSA:
43.37
HBD:
1.0
HBA:
#RotB:
0.0
Source:
GUSACITINIB
2
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Dermatitis; Dermatitis, Atopic
Janus Kinase (JAK) inhibitor
GUSACITINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
4801QYW816
Molecule Type:
Small molecule
Molecular Formula:
C24H28N8O2
Molecular Weight:
460.54
AlogP:
2.55
PSA:
134.06
HBD:
3.0
HBA:
#RotB:
5.0
Source:
LURTOTECAN
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Small Cell Lung Carcinoma
Unknown
LURTOTECAN
×
Maximum Phase:
2
First Approval:
None
UNII:
4J1L80T08I
Molecule Type:
Small molecule
Molecular Formula:
C28H30N4O6
Molecular Weight:
518.57
AlogP:
1.6
PSA:
106.36
HBD:
1.0
HBA:
#RotB:
3.0
Source:
AKN-028
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute
Tyrosine-protein kinase receptor FLT3 inhibitor
AKN-028
×
Maximum Phase:
2
First Approval:
None
UNII:
Y66IS3CS0R
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AXOMADOL
2
Small molecule
Investigational
Unknown
Unknown
Chronic Pain; Pain; Low Back Pain
Delta opioid receptor agonist
AXOMADOL
×
Maximum Phase:
2
First Approval:
None
UNII:
9J92U4CVS0
Molecule Type:
Small molecule
Molecular Formula:
C16H25NO3
Molecular Weight:
279.38
AlogP:
1.61
PSA:
52.93
HBD:
2.0
HBA:
#RotB:
4.0
Source:
ATRELEUTON
2
Small molecule
Investigational
Unknown
Unknown
Acute Coronary Syndrome; Atherosclerosis; Coronary Disease
Arachidonate 5-lipoxygenase inhibitor
ATRELEUTON
×
Maximum Phase:
2
First Approval:
None
UNII:
U301T88E1M
Molecule Type:
Small molecule
Molecular Formula:
C16H15FN2O2S
Molecular Weight:
318.37
AlogP:
2.99
PSA:
66.56
HBD:
2.0
HBA:
#RotB:
3.0
Source:
AZTREONAM LYSINE
2
Small molecule
Investigational
Unknown
Unknown
Bronchiectasis
Unknown
AZTREONAM LYSINE
×
Maximum Phase:
2
First Approval:
None
UNII:
XNM7LT65NP
Molecule Type:
Small molecule
Molecular Formula:
C19H31N7O10S2
Molecular Weight:
581.63
AlogP:
-1.17
PSA:
201.58
HBD:
4.0
HBA:
#RotB:
7.0
Source:
TARANABANT
3
Small molecule
Investigational
Unknown
Unknown
Tobacco Use Disorder; Urinary Incontinence; Diabetes Mellitus, Type 2; Obesity
Cannabinoid CB1 receptor inverse agonist
TARANABANT
×
Maximum Phase:
3
First Approval:
None
UNII:
X9U622S114
Molecule Type:
Small molecule
Molecular Formula:
C27H25ClF3N3O2
Molecular Weight:
515.96
AlogP:
6.31
PSA:
75.01
HBD:
1.0
HBA:
#RotB:
8.0
Source:
1
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140
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Compound Name
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Molecular Formula
Molecular Weight
ALogP
PSA