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Total: 6532
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
Small molecule
Investigational
Unknown
Unknown
Anemia, Sickle Cell; Bronchopulmonary Dysplasia; Diabetes Mellitus, Type 2; Endocardial Cushion Defects; Heart Septal Defects, Atrial; Heart Septal Defects, Ventricular; Hypertension; MELAS Syndrome; Asthma; Intermittent Claudication; Neoplasms; Peripheral Arterial Disease; Respiratory Insufficiency; Acute Lung Injury; Postpoliomyelitis Syndrome
Unknown
Small molecule
Investigational
Unknown
Unknown
Kidney Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Carcinoma, Transitional Cell; Endometrial Neoplasms; Neoplasms; Neuroendocrine Tumors; Severe Acute Respiratory Syndrome; Infections
PI3-kinase class I inhibitor
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus; Diabetes Mellitus, Type 2
Unknown
Small molecule
Investigational
Unknown
Unknown
Leukemia
P-glycoprotein 1 inhibitor
Small molecule
Investigational
Unknown
Unknown
Adrenal Cortex Neoplasms; Astrocytoma; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Colorectal Neoplasms; Ependymoma; Glioblastoma; Glioma; Head and Neck Neoplasms; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Melanoma; Meningioma; Mesothelioma; Multiple Myeloma; Neoplasms; Neuroblastoma; Neuroectodermal Tumors, Primitive; Oligodendroglioma; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdoid Tumor; Sarcoma; Small Cell Lung Carcinoma; Stomach Neoplasms; Urinary Bladder Neoplasms; Waldenstrom Macroglobulinemia
Unknown
Small molecule
Investigational
Unknown
Unknown
Constipation
Unknown
Small molecule
Investigational
Unknown
Unknown
Geographic Atrophy; Macular Degeneration; Stargardt Disease
Retinoid isomerohydrolase inhibitor
Small molecule
Investigational
Unknown
Unknown
Low Back Pain
Unknown
Small molecule
Investigational
Unknown
Unknown
Substance-Related Disorders; Anxiety; Dementia; Depressive Disorder; Schizophrenia
Unknown
Small molecule
Investigational
Unknown
Unknown
Unknown
Estrogen receptor modulator
Small molecule
Investigational
Unknown
Unknown
Gallbladder Neoplasms; Glioblastoma; Gliosarcoma; Oligodendroglioma; Pancreatic Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Urogenital Neoplasms; Brain Neoplasms; Neoplasm Metastasis
Ribonucleoside-diphosphate reductase RR1 inhibitor
Small molecule
Investigational
Unknown
Unknown
Dry Eye Syndromes; Gastritis
Unknown
Small molecule
Investigational
Unknown
Unknown
Burkitt Lymphoma; Chondrosarcoma; Colorectal Neoplasms; Head and Neck Neoplasms; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Prolymphocytic; Lung Neoplasms; Lymphoma; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Mycosis Fungoides; Osteosarcoma; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Sezary Syndrome; Stomach Neoplasms; Urinary Bladder Neoplasms; Waldenstrom Macroglobulinemia; Breast Neoplasms; Carcinoma, Medullary; Hodgkin Disease; Kidney Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Melanoma; Myeloproliferative Disorders; Neoplasms; Prostatic Neoplasms; Thyroid Neoplasms; Multiple Myeloma
Heat shock protein HSP90 inhibitor
Small molecule
Investigational
Unknown
Unknown
Angelman Syndrome; Depressive Disorder, Major; Fragile X Syndrome; Sleep Initiation and Maintenance Disorders
GABA-A receptor; agonist GABA site agonist
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
Small molecule
Investigational
Unknown
Unknown
Pneumonia; Pneumonia, Bacterial; Infections; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Investigational
Unknown
Unknown
Central Nervous System Neoplasms
Unknown
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Prostatic Hyperplasia
Unknown
Small molecule
Investigational
Unknown
Unknown
Andersen Syndrome; Hypertension; Arrhythmias, Cardiac
Unknown
Small molecule
Investigational
Unknown
Unknown
Colorectal Neoplasms; Fallopian Tube Neoplasms; Glioma; Kidney Diseases; Kidney Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Hodgkin Disease; Leukemia, Myeloid, Acute; Lymphoma; Melanoma; Myelodysplastic Syndromes; Neuroendocrine Tumors; Rectal Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Neoplasms
Histone deacetylase inhibitor
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major; Epilepsy, Temporal Lobe; Anxiety
Serotonin 1a (5-HT1a) receptor agonist
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
Small molecule
Investigational
Unknown
Unknown
Constipation; Heavy Metal Poisoning; Blepharitis; Dry Eye Syndromes
Unknown
Small molecule
Investigational
Unknown
Unknown
Unknown
Progesterone receptor agonist
Small molecule
Investigational
Unknown
Unknown
Acanthamoeba Keratitis; Eye Infections
Unknown
Small molecule
Investigational
Unknown
Unknown
Central Nervous System Neoplasms; Leukemia; Lymphoma; Myelodysplastic Syndromes; Neoplasms; Breast Neoplasms; Fallopian Tube Neoplasms; Liver Neoplasms; Lung Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Uterine Cervical Neoplasms; Pancreatic Neoplasms
Unknown
Small molecule
Investigational
Unknown
Unknown
Rhinitis, Allergic, Seasonal
Prostanoid DP receptor antagonist
Small molecule
Investigational
Unknown
Unknown
Eosinophilic Esophagitis
Unknown
Small molecule
Investigational
Unknown
Unknown
Pilonidal Sinus; Wounds and Injuries
Unknown
Small molecule
Investigational
Unknown
Unknown
Ischemic Stroke
Unknown
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis; Osteoarthritis, Knee; Osteoarthritis, Hip; Rheumatic Diseases
Carbonic anhydrase II inhibitor
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
Small molecule
Investigational
Unknown
Unknown
Cystic Fibrosis; Lupus Erythematosus, Systemic; Dermatomyositis; Scleroderma, Diffuse
Unknown
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Colorectal Neoplasms; Glioblastoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Thrombocythemia, Essential; Neoplasms; Polycythemia Vera; Leukemia, Myeloid, Acute
Tumour suppressor p53/oncoprotein Mdm2 inhibitor