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EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
SONOLISIB
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Glioblastoma; Prostatic Neoplasms, Castration-Resistant
PI3-kinase class I inhibitor
SONOLISIB
×
Maximum Phase:
2
First Approval:
None
UNII:
987796874T
Molecule Type:
Small molecule
Molecular Formula:
C29H35NO8
Molecular Weight:
525.6
AlogP:
3.13
PSA:
119.44
HBD:
1.0
HBA:
#RotB:
8.0
Source:
MANITIMUS
2
Small molecule
Investigational
Unknown
Unknown
Graft vs Host Disease; Kidney Diseases
Unknown
MANITIMUS
×
Maximum Phase:
2
First Approval:
None
UNII:
4B135RK2KL
Molecule Type:
Small molecule
Molecular Formula:
C14H10F3N3O2
Molecular Weight:
309.25
AlogP:
3.28
PSA:
96.91
HBD:
2.0
HBA:
#RotB:
4.0
Source:
E7449
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
E7449
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BIIB-023
2
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Lupus Nephritis
Tumor necrosis factor ligand superfamily member 12 inhibitor
BIIB-023
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CENPLACEL-L
2
Cell
Investigational
Unknown
Unknown
Sarcoidosis, Pulmonary; Arthritis, Rheumatoid; Crohn Disease
Unknown
CENPLACEL-L
×
Maximum Phase:
2
First Approval:
None
UNII:
OOH12XV6XR
Molecule Type:
Cell
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HGT-1410
2
Enzyme
Investigational
Unknown
Unknown
Unknown
Unknown
HGT-1410
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OSORESNONTRINE
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Mental Disorders; Schizophrenia
Unknown
OSORESNONTRINE
×
Maximum Phase:
2
First Approval:
None
UNII:
O9OC34WOAY
Molecule Type:
Small molecule
Molecular Formula:
C16H17N5O2
Molecular Weight:
311.35
AlogP:
1.46
PSA:
85.69
HBD:
1.0
HBA:
#RotB:
3.0
Source:
VILANTEROL .ALPHA.-PHENYL CINNAMATE
2
Small molecule
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Unknown
VILANTEROL .ALPHA.-PHENYL CINNAMATE
×
Maximum Phase:
2
First Approval:
None
UNII:
DB71X3OVN2
Molecule Type:
Small molecule
Molecular Formula:
C39H45Cl2NO7
Molecular Weight:
710.7
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
NEPICASTAT
2
Small molecule
Investigational
Unknown
Unknown
Cocaine-Related Disorders; Stress Disorders, Post-Traumatic
Unknown
NEPICASTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
VPG12K4540
Molecule Type:
Small molecule
Molecular Formula:
C14H15F2N3S
Molecular Weight:
295.36
AlogP:
2.64
PSA:
43.84
HBD:
2.0
HBA:
#RotB:
2.0
Source:
CINACIGUAT
2
Small molecule
Investigational
Unknown
Unknown
Heart Failure
Soluble guanylate cyclase activator
CINACIGUAT
×
Maximum Phase:
2
First Approval:
None
UNII:
59K0Y58UAD
Molecule Type:
Small molecule
Molecular Formula:
C36H39NO5
Molecular Weight:
565.71
AlogP:
7.05
PSA:
87.07
HBD:
2.0
HBA:
#RotB:
17.0
Source:
RALMITARONT
2
Small molecule
Investigational
Unknown
Unknown
Psychotic Disorders
Unknown
RALMITARONT
×
Maximum Phase:
2
First Approval:
None
UNII:
QA8MW1Q80P
Molecule Type:
Small molecule
Molecular Formula:
C17H22N4O2
Molecular Weight:
314.39
AlogP:
2.19
PSA:
79.04
HBD:
3.0
HBA:
#RotB:
4.0
Source:
FILOREXANT
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major; Diabetic Neuropathies; Sleep Initiation and Maintenance Disorders
Orexin receptor antagonist
FILOREXANT
×
Maximum Phase:
2
First Approval:
None
UNII:
E6BTT8VA5Z
Molecule Type:
Small molecule
Molecular Formula:
C24H25FN4O2
Molecular Weight:
420.49
AlogP:
4.31
PSA:
68.21
HBD:
0.0
HBA:
#RotB:
5.0
Source:
HMPL-453
2
Unknown
Investigational
Unknown
Unknown
Neoplasms; Bile Duct Neoplasms; Mesothelioma
Fibroblast growth factor receptor 1 inhibitor
HMPL-453
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
O-CHLOROACETYLCARBAMOYLFUMAGILLOL
2
Small molecule
Investigational
Unknown
Unknown
Pancreatic Neoplasms
Unknown
O-CHLOROACETYLCARBAMOYLFUMAGILLOL
×
Maximum Phase:
2
First Approval:
None
UNII:
X47GR46481
Molecule Type:
Small molecule
Molecular Formula:
C19H28ClNO6
Molecular Weight:
401.89
AlogP:
2.55
PSA:
89.69
HBD:
1.0
HBA:
#RotB:
6.0
Source:
DCDP
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
DCDP
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GW590735
2
Small molecule
Investigational
Unknown
Unknown
Lipid Metabolism Disorders
Peroxisome proliferator-activated receptor alpha agonist
GW590735
×
Maximum Phase:
2
First Approval:
None
UNII:
QKY617BBX5
Molecule Type:
Small molecule
Molecular Formula:
C23H21F3N2O4S
Molecular Weight:
478.49
AlogP:
5.31
PSA:
88.52
HBD:
2.0
HBA:
#RotB:
7.0
Source:
UK-390957
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
UK-390957
×
Maximum Phase:
2
First Approval:
None
UNII:
W26I0D1D6J
Molecule Type:
Small molecule
Molecular Formula:
C16H20N2O3S2
Molecular Weight:
352.48
AlogP:
2.91
PSA:
72.63
HBD:
1.0
HBA:
#RotB:
6.0
Source:
7-ETHYL-10-HYDROXYCAMPTOTHECIN
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Small Cell Lung Carcinoma
DNA topoisomerase I inhibitor
7-ETHYL-10-HYDROXYCAMPTOTHECIN
×
Maximum Phase:
2
First Approval:
None
UNII:
0H43101T0J
Molecule Type:
Small molecule
Molecular Formula:
C22H20N2O5
Molecular Weight:
392.41
AlogP:
2.35
PSA:
101.65
HBD:
2.0
HBA:
#RotB:
2.0
Source:
PATIDEGIB
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Pancreatic Neoplasms; Carcinoma, Basal Cell; Chondrosarcoma; Basal Cell Nevus Syndrome
Smoothened homolog antagonist
PATIDEGIB
×
Maximum Phase:
2
First Approval:
None
UNII:
JT96FPU35X
Molecule Type:
Small molecule
Molecular Formula:
C29H48N2O3S
Molecular Weight:
504.78
AlogP:
5.03
PSA:
67.43
HBD:
2.0
HBA:
#RotB:
2.0
Source:
IOTA-CARRAGEENAN
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
IOTA-CARRAGEENAN
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MITEMCINAL FUMARATE
2
Small molecule
Investigational
Unknown
Unknown
Gastroparesis
Motilin receptor agonist
MITEMCINAL FUMARATE
×
Maximum Phase:
2
First Approval:
None
UNII:
XU63LQ260J
Molecule Type:
Small molecule
Molecular Formula:
C44H73NO16
Molecular Weight:
872.06
AlogP:
4.53
PSA:
151.68
HBD:
2.0
HBA:
#RotB:
9.0
Source:
PREP-001
2
Unknown
Investigational
Unknown
Unknown
Asthma; Infections
Unknown
PREP-001
×
Maximum Phase:
2
First Approval:
None
UNII:
4O2Z043B1C
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BI-187004
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
11-beta-hydroxysteroid dehydrogenase 1 inhibitor
BI-187004
×
Maximum Phase:
2
First Approval:
None
UNII:
280XKM6Z2K
Molecule Type:
Small molecule
Molecular Formula:
C21H18N4O
Molecular Weight:
342.4
AlogP:
3.38
PSA:
72.78
HBD:
1.0
HBA:
#RotB:
1.0
Source:
TUVIRUMAB
2
Antibody
Investigational
Unknown
Unknown
Unknown
Major surface antigen inhibitor
TUVIRUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
31Z0AB5WNC
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INTERLEUKIN-10
2
Unknown
Investigational
Unknown
Unknown
Granulomatosis with Polyangiitis; Psoriasis
Unknown
INTERLEUKIN-10
×
Maximum Phase:
2
First Approval:
None
UNII:
9SC4O216V9
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MOL-4239
2
Small molecule
Investigational
Unknown
Unknown
Mycosis Fungoides; Psoriasis
Unknown
MOL-4239
×
Maximum Phase:
2
First Approval:
None
UNII:
PTN9LJL6PY
Molecule Type:
Small molecule
Molecular Formula:
C19H16BrN3O
Molecular Weight:
382.26
AlogP:
4.18
PSA:
65.78
HBD:
1.0
HBA:
#RotB:
5.0
Source:
ABT-384
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
11-beta-hydroxysteroid dehydrogenase 1 inhibitor
ABT-384
×
Maximum Phase:
2
First Approval:
None
UNII:
R5TH77F919
Molecule Type:
Small molecule
Molecular Formula:
C25H34F3N5O2
Molecular Weight:
493.57
AlogP:
2.8
PSA:
91.56
HBD:
2.0
HBA:
#RotB:
5.0
Source:
ELSAMITRUCIN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ELSAMITRUCIN
×
Maximum Phase:
2
First Approval:
None
UNII:
ZTV0FOB6NU
Molecule Type:
Small molecule
Molecular Formula:
C33H35NO13
Molecular Weight:
653.64
AlogP:
1.73
PSA:
213.51
HBD:
5.0
HBA:
#RotB:
5.0
Source:
EMAPUNIL
2
Small molecule
Investigational
Unknown
Unknown
Anxiety
Translocator protein agonist
EMAPUNIL
×
Maximum Phase:
2
First Approval:
None
UNII:
OG837L732J
Molecule Type:
Small molecule
Molecular Formula:
C23H23N5O2
Molecular Weight:
401.47
AlogP:
2.85
PSA:
73.02
HBD:
0.0
HBA:
#RotB:
6.0
Source:
COTININE FUMARATE
2
Small molecule
Investigational
Unknown
Unknown
Tobacco Use Disorder
Unknown
COTININE FUMARATE
×
Maximum Phase:
2
First Approval:
None
UNII:
6ZAF060BHS
Molecule Type:
Small molecule
Molecular Formula:
C24H28N4O6
Molecular Weight:
468.51
AlogP:
1.37
PSA:
33.2
HBD:
0.0
HBA:
#RotB:
1.0
Source:
MK-6913
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Estrogen receptor agonist
MK-6913
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C25H27N3O2
Molecular Weight:
401.51
AlogP:
4.94
PSA:
57.01
HBD:
0.0
HBA:
#RotB:
4.0
Source:
LYS-SAF302
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LYS-SAF302
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TRABODENOSON
2
Small molecule
Investigational
Unknown
Unknown
Glaucoma, Open-Angle; Ocular Hypertension
Adenosine A1 receptor agonist
TRABODENOSON
×
Maximum Phase:
2
First Approval:
None
UNII:
1T237110W4
Molecule Type:
Small molecule
Molecular Formula:
C15H20N6O6
Molecular Weight:
380.36
AlogP:
0.01
PSA:
157.69
HBD:
3.0
HBA:
#RotB:
6.0
Source:
PL-3994
2
Protein
Investigational
Unknown
Unknown
Asthma; Heart Failure
Atrial natriuretic peptide receptor A agonist
PL-3994
×
Maximum Phase:
2
First Approval:
None
UNII:
YI2S0GUQ2C
Molecule Type:
Protein
Molecular Formula:
C82H127N27O20S2
Molecular Weight:
1875.22
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
CTCE-9908
2
Protein
Investigational
Unknown
Unknown
Unknown
C-X-C chemokine receptor type 4 antagonist
CTCE-9908
×
Maximum Phase:
2
First Approval:
None
UNII:
NF0BX95A31
Molecule Type:
Protein
Molecular Formula:
C86H147N27O23
Molecular Weight:
1927.29
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
1
2
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199
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PSA