DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Unknown Unknown Unknown Depressive Disorder; Tobacco Use Disorder Neuronal acetylcholine receptor; alpha4/beta2 agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM INTRAMUSCULAR Bulimia; Alcohol Drinking; Child Development Disorders, Pervasive; Dermatitis, Atopic; Psoriasis; Schizophrenia; Alcohol-Related Disorders; Amphetamine-Related Disorders; Breast Neoplasms; Colitis, Ulcerative; Coronavirus Infections; Crohn Disease; Cystitis, Interstitial; Depressive Disorder, Major; Diabetic Neuropathies; Dry Eye Syndromes; Fibromyalgia; Low Back Pain; Marijuana Abuse; Migraine Disorders; Obsessive-Compulsive Disorder; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Trichotillomania; Borderline Personality Disorder; Chronic Pain; Cocaine-Related Disorders; Depressive Disorder; Endometriosis; Gambling; Heroin Dependence; HIV Infections; Multiple Sclerosis; Obesity; Opioid-Related Disorders; Pain; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Tobacco Use Disorder; Alcoholism Opioid receptors; mu/kappa/delta antagonist

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM

INTRAMUSCULAR

Bulimia; Alcohol Drinking; Child Development Disorders, Pervasive; Dermatitis, Atopic; Psoriasis; Schizophrenia; Alcohol-Related Disorders; Amphetamine-Related Disorders; Breast Neoplasms; Colitis, Ulcerative; Coronavirus Infections; Crohn Disease; Cystitis, Interstitial; Depressive Disorder, Major; Diabetic Neuropathies; Dry Eye Syndromes; Fibromyalgia; Low Back Pain; Marijuana Abuse; Migraine Disorders; Obsessive-Compulsive Disorder; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Trichotillomania; Borderline Personality Disorder; Chronic Pain; Cocaine-Related Disorders; Depressive Disorder; Endometriosis; Gambling; Heroin Dependence; HIV Infections; Multiple Sclerosis; Obesity; Opioid-Related Disorders; Pain; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Tobacco Use Disorder; Alcoholism

Opioid receptors; mu/kappa/delta antagonist


Small molecule Approved OTHER INJECTION Unknown Phosphodiesterase 3A inhibitor


Small molecule Approved Unknown Unknown Lung Diseases, Obstructive Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Atherosclerosis; Renal Insufficiency, Chronic; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker


Small molecule Approved Unknown Unknown Arthralgia; Eye Diseases; Myalgia Xanthine dehydrogenase inhibitor


Small molecule Approved Unknown Unknown Constipation; Heart Arrest; Heroin Dependence; Restless Legs Syndrome; Rheumatic Diseases; Blood Coagulation Disorders; Chronic Pain; Fractures, Multiple; Hemorrhage; Mucositis; Neuralgia; Postoperative Complications; Premature Birth; Respiratory Insufficiency; Rotator Cuff Injuries; Stomatitis; Tonsillitis; Anemia, Sickle Cell; Back Pain; Dyspnea; Fractures, Bone; Kidney Calculi; Leukemia, Myeloid, Acute; Myocardial Infarction; Neonatal Abstinence Syndrome; Neoplasms; Obesity; Opioid-Related Disorders; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Pruritus; Pulmonary Disease, Chronic Obstructive; Renal Colic; Scoliosis; Sleep Apnea, Obstructive; Wounds and Injuries; Pain Unknown

Small molecule

Approved

Unknown

Constipation; Heart Arrest; Heroin Dependence; Restless Legs Syndrome; Rheumatic Diseases; Blood Coagulation Disorders; Chronic Pain; Fractures, Multiple; Hemorrhage; Mucositis; Neuralgia; Postoperative Complications; Premature Birth; Respiratory Insufficiency; Rotator Cuff Injuries; Stomatitis; Tonsillitis; Anemia, Sickle Cell; Back Pain; Dyspnea; Fractures, Bone; Kidney Calculi; Leukemia, Myeloid, Acute; Myocardial Infarction; Neonatal Abstinence Syndrome; Neoplasms; Obesity; Opioid-Related Disorders; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Pruritus; Pulmonary Disease, Chronic Obstructive; Renal Colic; Scoliosis; Sleep Apnea, Obstructive; Wounds and Injuries; Pain

Unknown


Small molecule Approved OTHER VAGINAL Bacterial Infections Bacterial dihydropteroate synthase inhibitor


Small molecule Unknown Unknown Unknown Cheilitis; Erythema; Stomatitis; Skin Diseases; Eye Diseases; Skin Ulcer Unknown


Small molecule Approved Unknown Unknown Multiple Sclerosis; Acidosis, Lactic; Heart Arrest; Huntington Disease; Respiratory Insufficiency; Heart Failure; Hyperemesis Gravidarum; Sepsis; Shock, Septic; Anemia; Brain Diseases; Kidney Failure, Chronic; Thiamine Deficiency Unknown


Small molecule Approved Unknown Unknown Osteomyelitis; Sepsis; Infections; Pyelonephritis; Urinary Tract Infections; Bacterial Infections; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated Renal dipeptidase inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Glaucoma Unknown


Small molecule Approved OTHER ORAL Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved Unknown Unknown Neoplasms; Pulmonary Alveolar Proteinosis; Atherosclerosis; Attention Deficit Disorder with Hyperactivity; Colorectal Neoplasms; Epilepsy; Heart Failure; HIV Infections; Lymphoma; Multiple Myeloma; Myocardial Infarction; Myocardial Ischemia; Psychotic Disorders; Tuberculosis, Pulmonary; Alzheimer Disease; Hand-Foot Syndrome; Movement Disorders; Non-alcoholic Fatty Liver Disease; Spasms, Infantile; Tuberculosis; Anemia; Diabetes Mellitus, Type 2; Kidney Failure, Chronic; Osteoporosis; Postoperative Nausea and Vomiting Unknown

Small molecule

Approved

Unknown

Neoplasms; Pulmonary Alveolar Proteinosis; Atherosclerosis; Attention Deficit Disorder with Hyperactivity; Colorectal Neoplasms; Epilepsy; Heart Failure; HIV Infections; Lymphoma; Multiple Myeloma; Myocardial Infarction; Myocardial Ischemia; Psychotic Disorders; Tuberculosis, Pulmonary; Alzheimer Disease; Hand-Foot Syndrome; Movement Disorders; Non-alcoholic Fatty Liver Disease; Spasms, Infantile; Tuberculosis; Anemia; Diabetes Mellitus, Type 2; Kidney Failure, Chronic; Osteoporosis; Postoperative Nausea and Vomiting

Unknown


Small molecule Approved Unknown Unknown Melanoma; Neoplasms; Cardiomyopathy, Hypertrophic; Hepatolenticular Degeneration Unknown


Small molecule Approved Unknown Unknown Endocarditis; Infections; Intraabdominal Infections; Pneumonia; Sepsis; Urinary Tract Infections Renal dipeptidase inhibitor


Small molecule Approved Unknown Unknown Osteomyelitis; Cholecystitis; Bacterial Infections Unknown


Small molecule Approved OTHER ORAL Cognitive Dysfunction; Joint Diseases; Alcoholism; Anemia, Sickle Cell; Bipolar Disorder; Essential Tremor; Multiple Sclerosis; Schizophrenia; Substance-Related Disorders; Alcohol Drinking; Amyotrophic Lateral Sclerosis; Arthritis, Psoriatic; Chronic Pain; Dementia; HIV Infections; Irritable Bowel Syndrome; Marijuana Abuse; Migraine with Aura; Migraine without Aura; Opioid-Related Disorders; Pain; Sleep Apnea, Obstructive; Stress Disorders, Post-Traumatic; Torticollis; Tourette Syndrome; Trichotillomania; Anorexia Nervosa; Osteoarthritis, Knee; Anorexia; Nausea; Neoplasms; Postoperative Nausea and Vomiting Cannabinoid CB1 receptor agonist

Small molecule

Approved

OTHER

ORAL

Cognitive Dysfunction; Joint Diseases; Alcoholism; Anemia, Sickle Cell; Bipolar Disorder; Essential Tremor; Multiple Sclerosis; Schizophrenia; Substance-Related Disorders; Alcohol Drinking; Amyotrophic Lateral Sclerosis; Arthritis, Psoriatic; Chronic Pain; Dementia; HIV Infections; Irritable Bowel Syndrome; Marijuana Abuse; Migraine with Aura; Migraine without Aura; Opioid-Related Disorders; Pain; Sleep Apnea, Obstructive; Stress Disorders, Post-Traumatic; Torticollis; Tourette Syndrome; Trichotillomania; Anorexia Nervosa; Osteoarthritis, Knee; Anorexia; Nausea; Neoplasms; Postoperative Nausea and Vomiting

Cannabinoid CB1 receptor agonist


Small molecule Approved Unknown Unknown Coronary Disease; Amyloidosis, Familial; Hemorrhagic Fever, Ebola; Severe Acute Respiratory Syndrome; Tachycardia, Supraventricular; Atrial Fibrillation; Atrial Flutter; Cardiomyopathies; Death, Sudden, Cardiac; Heart Arrest; Heart Failure; Myocardial Infarction; Tachycardia, Ventricular; Ventricular Fibrillation; Arrhythmias, Cardiac Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Glaucoma, Open-Angle; Ocular Hypertension; Cardiovascular Diseases; Glaucoma Unknown


Small molecule Approved OTHER BILIARY; PERFUSION Unknown Unknown


Small molecule Approved OTHER INJECTION; ORAL Shock, Septic; Acquired Immunodeficiency Syndrome; beta-Thalassemia; Diabetes Mellitus, Type 2; Heart Failure; Muscle Cramp; Neoplasms; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Renal Insufficiency, Chronic; Spinal Cord Injuries; Acute Kidney Injury; Atrial Fibrillation; Cytomegalovirus Infections; Gastrointestinal Stromal Tumors; HIV Infections; Hyperthyroidism; Lipid Metabolism Disorders; Multiple Sclerosis; Muscular Atrophy, Spinal; Pancreatic Neoplasms; Peripheral Arterial Disease; Pyelonephritis; Sarcopenia; Brain Diseases; Kidney Failure, Chronic; Muscle Weakness Unknown

Small molecule

Approved

OTHER

INJECTION; ORAL

Shock, Septic; Acquired Immunodeficiency Syndrome; beta-Thalassemia; Diabetes Mellitus, Type 2; Heart Failure; Muscle Cramp; Neoplasms; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Renal Insufficiency, Chronic; Spinal Cord Injuries; Acute Kidney Injury; Atrial Fibrillation; Cytomegalovirus Infections; Gastrointestinal Stromal Tumors; HIV Infections; Hyperthyroidism; Lipid Metabolism Disorders; Multiple Sclerosis; Muscular Atrophy, Spinal; Pancreatic Neoplasms; Peripheral Arterial Disease; Pyelonephritis; Sarcopenia; Brain Diseases; Kidney Failure, Chronic; Muscle Weakness

Unknown


Small molecule Approved Unknown Unknown Arrhythmogenic Right Ventricular Dysplasia; Atrial Fibrillation; Arrhythmias, Cardiac Unknown


Small molecule Approved Unknown Unknown Irritable Bowel Syndrome; Blepharospasm; Charcot-Marie-Tooth Disease; Chronic Pain; Death, Sudden, Cardiac; Myocardial Infarction; Myotonic Dystrophy; Ventricular Fibrillation; Arrhythmias, Cardiac Unknown


Small molecule Approved OTHER INJECTION Osteomyelitis; Cystic Fibrosis; Esophageal Achalasia; Meningitis, Bacterial; Enterobacteriaceae Infections; Skin Diseases; Staphylococcal Skin Infections; Bacterial Infections; Infections; Intraabdominal Infections; Parametritis; Peritonitis; Pneumonia; Pyelonephritis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Small molecule Unknown Unknown Unknown Amyloidosis, Familial; Atrial Fibrillation; Chagas Cardiomyopathy; Heart Failure; Arrhythmias, Cardiac; Tachycardia, Ventricular; Ventricular Fibrillation HERG blocker

Small molecule

Approved

Unknown

Barrett Esophagus; Erectile Dysfunction; Ischemia; Renal Insufficiency, Chronic; Cerebral Hemorrhage; Diabetes Mellitus, Type 1; Essential Hypertension; Glomerulonephritis, IGA; Heart Diseases; Melanoma; Pseudohypoaldosteronism; Stroke; Cardiomyopathies; Cardiotoxicity; Chagas Cardiomyopathy; Heart Failure; Hypertension; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Multiple Myeloma; Myocardial Ischemia; Neoplasms; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Cardiovascular Diseases

Unknown


Small molecule Approved OTHER TOPICAL Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved Unknown Unknown Anemia, Sickle Cell; Amyotrophic Lateral Sclerosis; Anemia, Neonatal; Heart Failure; Huntington Disease; Multiple Sclerosis; Anemia; Anemia, Iron-Deficiency; Diabetes Mellitus, Type 2; Kidney Failure, Chronic Unknown


Protein Approved OTHER INJECTION Hyperglycemia; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Hypertension Insulin receptor agonist


Small molecule Approved Unknown Unknown Cough Opioid receptors; mu/kappa/delta agonist

Small molecule

Approved

Unknown

INTRAVENOUS

Carcinoma, Basal Cell; Postpartum Hemorrhage; Urinary Tract Infections; Acne Vulgaris; Ascorbic Acid Deficiency; Asthma; Astrocytoma; Autistic Disorder; Breast Neoplasms; Burns; Carcinoma, Pancreatic Ductal; Colonic Neoplasms; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Gliosarcoma; Hypertension; Hypoxia; Neoplasms; Oligodendroglioma; Osteoarthritis; Polycythemia Vera; Primary Myelofibrosis; Pulmonary Alveolar Proteinosis; Sarcoma; Temporomandibular Joint Disorders; Thrombocythemia, Essential; Urinary Bladder Neoplasms; Acute Lung Injury; beta-Thalassemia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carotid Artery Diseases; Charcot-Marie-Tooth Disease; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsy; Fatigue; Glioblastoma; Heart Arrest; Heart Diseases; Heart Failure; Hodgkin Disease; Inflammation; Intracranial Arteriosclerosis; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma, Non-Hodgkin; Multiple Myeloma; Muscular Diseases; Myelodysplastic Syndromes; Myocardial Infarction; Ovarian Neoplasms; Pancreatic Neoplasms; Pre-Eclampsia; Prostatic Neoplasms; Rectal Neoplasms; Renal Insufficiency, Chronic; Shock; Stomatitis; Tobacco Use Disorder; Uterine Cervical Neoplasms; Virus Diseases; Wounds and Injuries; Anorexia; Atrial Fibrillation; Atrial Flutter; Cataract; Colorectal Neoplasms; Complex Regional Pain Syndromes; Diabetes Mellitus; Glioma; Leiomyoma; Macular Degeneration; Menopause; Myocardial Ischemia; Pain; Respiratory Distress Syndrome; Respiratory Tract Infections; Schizophrenia; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Stomach Neoplasms; Anemia; Anemia, Iron-Deficiency; Eye Diseases; Kidney Failure, Chronic; Pneumonia; Scurvy

Supplement