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Total: 10647
Protein
Approved
Unknown
SUBCUTANEOUS
Diabetes Mellitus, Type 1; Parkinson Disease; Acute Coronary Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 2
Glucagon-like peptide 1 receptor agonist
Small molecule
Approved
Unknown
Unknown
Hepatitis, Viral, Human; Hepatitis C; Hepatitis C, Chronic; Virus Diseases
Nonstructural protein 5A inhibitor
Small molecule
Approved
Unknown
ORAL
Amyloidosis, Familial; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Kidney Diseases; Leukemia; Leukemia, Prolymphocytic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Small Cell Lung Carcinoma; Blast Crisis; Breast Neoplasms; Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Prolymphocytic, T-Cell; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Waldenstrom Macroglobulinemia; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Multiple Myeloma; Myelodysplastic Syndromes; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms
Apoptosis regulator Bcl-2 inhibitor
Small molecule
Approved
Unknown
INTRAVENOUS; ORAL
Cytomegalovirus Infections; Infections; Virus Diseases
DNA terminase inhibitor
Protein
Approved
Unknown
ORAL
Irritable Bowel Syndrome; Constipation
Heat-stable enterotoxin receptor agonist
Antibody
Approved
Unknown
INJECTION
Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, T-Cell, Cutaneous; Melanoma; Neoplasm Metastasis; Plasmacytoma; Polycythemia Vera; Primary Myelofibrosis; Skin Neoplasms; Triple Negative Breast Neoplasms; Adenocarcinoma; Adenocarcinoma, Clear Cell; Adenocarcinoma, Follicular; Adenocarcinoma of Lung; Anus Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Large Cell; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Colorectal Neoplasms; Dysgerminoma; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Glioblastoma; Head and Neck Neoplasms; Hemangiosarcoma; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mouth Neoplasms; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Seminoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Thyroid Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Mesothelioma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms
Programmed cell death 1 ligand 1 inhibitor
Antibody
Approved
Unknown
INJECTION
Hemophilia A; Hemorrhage
Coagulation factor IX and X other
Antibody
Approved
Unknown
INJECTION
Scleroderma, Systemic; Arthritis, Rheumatoid; Asthma; Crohn Disease; Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Immune System Diseases; Psoriasis
Interleukin-17 receptor A antagonist
Protein
Approved
Unknown
Unknown
Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic
Calcium sensing receptor agonist
Small molecule
Unknown
Unknown
Unknown
Precursor Cell Lymphoblastic Leukemia-Lymphoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colonic Neoplasms; Lymphoma; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency; Breast Neoplasms; Cholangiocarcinoma; Gallbladder Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Neoplasms
PI3-kinase p110-alpha subunit inhibitor
Protein
Approved
Unknown
INTRAVENOUS
Unknown
Unknown
Small molecule
Approved
Unknown
ORAL
Lymphoma, Large-Cell, Anaplastic; Carcinoma, Non-Small-Cell Lung; Neoplasms
ALK tyrosine kinase receptor inhibitor
Small molecule
Unknown
Unknown
Unknown
Diarrhea
Tryptophan 5-hydroxylase inhibitor
Antibody
Approved
Unknown
INJECTION
Alopecia Areata; Angioedema; Conjunctivitis, Allergic; Netherton Syndrome; Peanut Hypersensitivity; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Pruritus; Respiratory Tract Diseases; Rhinitis, Allergic, Seasonal; Scleroderma, Localized; Severe Acute Respiratory Syndrome; Aspergillosis, Allergic Bronchopulmonary; Asthma; Dermatitis; Eosinophilic Esophagitis; Neurodermatitis; Pulmonary Disease, Chronic Obstructive; Sinusitis; Urticaria; Dermatitis, Atopic; Eczema; Nasal Polyps
Interleukin-4 receptor subunit alpha antagonist
Antibody
Approved
Unknown
INJECTION
Scleroderma, Localized; Arthritis, Juvenile; Mastocytosis, Systemic; Spondylitis, Ankylosing; Uveitis; Giant Cell Arteritis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Arthritis, Rheumatoid; Immune System Diseases
Interleukin-6 receptor alpha subunit antagonist
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Protein
Approved
Unknown
ORAL; SUBCUTANEOUS
Bone Diseases, Metabolic; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Parkinson Disease; Alzheimer Disease; Non-alcoholic Fatty Liver Disease; Obesity; Diabetes Mellitus; Diabetes Mellitus, Type 2
Glucagon-like peptide 1 receptor agonist
Small molecule
Approved
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Antibody
Approved
Unknown
INJECTION
Lymphoma, Non-Hodgkin; Encephalitis, Japanese; Arthritis, Rheumatoid; Lupus Erythematosus, Systemic; Immune System Diseases; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting
B-lymphocyte antigen CD20 binding agent
Small molecule
Approved
Unknown
ORAL
Glioma; Urinary Bladder Neoplasms; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteosarcoma; Pancreatic Neoplasms; Rhabdoid Tumor; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Kaposi; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Genital Neoplasms, Female; Glioblastoma; Head and Neck Neoplasms; Lung Neoplasms; Lymphoma, Mantle-Cell; Melanoma; Mesothelioma; Oligodendroglioma; Prostatic Neoplasms, Castration-Resistant; Thyroid Neoplasms; Carcinoma, Non-Small-Cell Lung; Liposarcoma; Breast Neoplasms; Neoplasms
Cyclin-dependent kinase 4 inhibitor
Small molecule
Approved
Unknown
ORAL
Breast Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
Unknown
Unknown
Astrocytoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Lymphoma; Neuroblastoma; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Liposarcoma; Melanoma; Neoplasms; Neuroendocrine Tumors; Ovarian Neoplasms; Sarcoma; Teratoma; Thymus Neoplasms; Uterine Neoplasms; Breast Neoplasms
Cyclin-dependent kinase 4 inhibitor
Small molecule
Approved
Unknown
Unknown
Liver Diseases; Pneumonia; Gonorrhea; Infections; Pneumonia, Bacterial; Bacterial Infections
Unknown
Protein
Approved
Unknown
INTRAVENOUS
Shock, Septic
Type-1 angiotensin II receptor agonist
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Liver Diseases; Multiple System Atrophy; Parkinson Disease
Monoamine oxidase B inhibitor
Small molecule
Approved
Unknown
ORAL
Vaginal Discharge; Infections; Trichomonas Infections; Vaginosis, Bacterial
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Tourette Syndrome; Huntington Disease; Movement Disorders
Synaptic vesicular amine transporter inhibitor
Antibody
Approved
Unknown
INJECTION
Dermatitis, Atopic; Hematologic Diseases; Sinusitis; Urticaria; Eosinophilic Esophagitis; Hypereosinophilic Syndrome; Nasal Polyps; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Asthma; Lung Diseases, Obstructive
Interleukin-5 receptor subunit alpha inhibitor
Small molecule
Approved
Unknown
Unknown
Pancreatitis; Constipation
Mu opioid receptor antagonist
Protein
Approved
Unknown
Unknown
Hypotension, Orthostatic; Renal Insufficiency; Hypertension; Shock, Septic; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Renal Insufficiency, Chronic; Kidney Diseases; Liver Diseases; Hepatitis C; Hepatitis C, Chronic
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Small molecule
Approved
Unknown
ORAL
Kidney Diseases; Liver Diseases; Atrial Fibrillation; Atrial Flutter; Hemorrhage; Thromboembolism; Thrombosis; Venous Thromboembolism
Coagulation factor X inhibitor
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
TOPICAL
Wounds and Injuries; Impetigo
DNA gyrase inhibitor
Small molecule
Approved
Unknown
Unknown
Bacterial Infections; Renal Insufficiency; Urinary Tract Infections
Carbepenem-hydrolyzing beta-lactamase KPC inhibitor