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Therapeutic Area
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CARDIOVASCULAR (45)
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
ENCALERET
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ENCALERET
×
Maximum Phase:
2
First Approval:
None
UNII:
EF8081AQ6G
Molecule Type:
Small molecule
Molecular Formula:
C29H33ClFNO4
Molecular Weight:
514.04
AlogP:
6.2
PSA:
78.79
HBD:
3.0
HBA:
#RotB:
11.0
Source:
T-817
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
T-817
×
Maximum Phase:
2
First Approval:
None
UNII:
QY49O94S2W
Molecule Type:
Small molecule
Molecular Formula:
C16H21NO2S
Molecular Weight:
291.42
AlogP:
2.53
PSA:
32.7
HBD:
1.0
HBA:
#RotB:
7.0
Source:
AMELUBANT
2
Small molecule
Investigational
Unknown
Unknown
Cystic Fibrosis; Arthritis, Rheumatoid; Asthma; Pulmonary Disease, Chronic Obstructive
Leukotriene B4 receptor 1 antagonist
AMELUBANT
×
Maximum Phase:
2
First Approval:
None
UNII:
E0018IF0K4
Molecule Type:
Small molecule
Molecular Formula:
C33H34N2O5
Molecular Weight:
538.64
AlogP:
6.95
PSA:
100.87
HBD:
3.0
HBA:
#RotB:
10.0
Source:
GRC-17536
2
Small molecule
Investigational
Unknown
Unknown
Diabetic Neuropathies
Transient receptor potential cation channel subfamily A member 1 antagonist
GRC-17536
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GTX-758
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Estrogen receptor alpha agonist
GTX-758
×
Maximum Phase:
2
First Approval:
None
UNII:
406GR1485Z
Molecule Type:
Small molecule
Molecular Formula:
C19H13F2NO3
Molecular Weight:
341.31
AlogP:
4.35
PSA:
60.77
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PIPERINE
2
Small molecule
Investigational
Unknown
Unknown
Deglutition Disorders; Pain
Unknown
PIPERINE
×
Maximum Phase:
2
First Approval:
None
UNII:
U71XL721QK
Molecule Type:
Small molecule
Molecular Formula:
C17H19NO3
Molecular Weight:
285.34
AlogP:
3.0
PSA:
38.77
HBD:
0.0
HBA:
#RotB:
3.0
Source:
JNJ-37822681
2
Small molecule
Investigational
Unknown
Unknown
Schizophrenia
Dopamine D2 receptor antagonist
JNJ-37822681
×
Maximum Phase:
2
First Approval:
None
UNII:
GJB2URS7NJ
Molecule Type:
Small molecule
Molecular Formula:
C17H17F5N4
Molecular Weight:
372.34
AlogP:
3.85
PSA:
41.05
HBD:
1.0
HBA:
#RotB:
4.0
Source:
NEVANIMIBE HYDROCHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Cushing Syndrome
Unknown
NEVANIMIBE HYDROCHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
TK694ZFS57
Molecule Type:
Small molecule
Molecular Formula:
C27H40ClN3O
Molecular Weight:
458.09
AlogP:
6.63
PSA:
44.37
HBD:
2.0
HBA:
#RotB:
7.0
Source:
PELITREXOL
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Colorectal Neoplasms; Lung Neoplasms
Unknown
PELITREXOL
×
Maximum Phase:
2
First Approval:
None
UNII:
DHT6E8M4KP
Molecule Type:
Small molecule
Molecular Formula:
C20H25N5O6S
Molecular Weight:
463.52
AlogP:
0.99
PSA:
187.5
HBD:
6.0
HBA:
#RotB:
9.0
Source:
AR-12286
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AR-12286
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-986142
2
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis; Arthritis, Rheumatoid
Tyrosine-protein kinase BTK inhibitor
BMS-986142
×
Maximum Phase:
2
First Approval:
None
UNII:
PJX9GH268R
Molecule Type:
Small molecule
Molecular Formula:
C32H30F2N4O4
Molecular Weight:
572.61
AlogP:
4.4
PSA:
123.11
HBD:
3.0
HBA:
#RotB:
4.0
Source:
AMG-208
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Prostatic Neoplasms, Castration-Resistant
Hepatocyte growth factor receptor inhibitor
AMG-208
×
Maximum Phase:
2
First Approval:
None
UNII:
Y2SR66P7VM
Molecule Type:
Small molecule
Molecular Formula:
C22H17N5O2
Molecular Weight:
383.41
AlogP:
3.93
PSA:
74.43
HBD:
0.0
HBA:
#RotB:
5.0
Source:
ITACITINIB ADIPATE
2
Small molecule
Investigational
Unknown
Unknown
Bronchiolitis Obliterans
Unknown
ITACITINIB ADIPATE
×
Maximum Phase:
2
First Approval:
None
UNII:
XZG407XE0Y
Molecule Type:
Small molecule
Molecular Formula:
C32H33F4N9O5
Molecular Weight:
699.67
AlogP:
3.6
PSA:
119.62
HBD:
1.0
HBA:
#RotB:
5.0
Source:
CAPESEROD
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Serotonin 4 (5-HT4) receptor partial agonist
CAPESEROD
×
Maximum Phase:
2
First Approval:
None
UNII:
8163770L8P
Molecule Type:
Small molecule
Molecular Formula:
C23H25ClN4O4
Molecular Weight:
456.93
AlogP:
3.39
PSA:
95.75
HBD:
1.0
HBA:
#RotB:
5.0
Source:
ALBACONAZOLE
2
Small molecule
Investigational
Unknown
Unknown
Tinea Pedis; Vulvovaginitis
Lanosterol 14-alpha demethylase inhibitor
ALBACONAZOLE
×
Maximum Phase:
2
First Approval:
None
UNII:
YDW24Y8IAB
Molecule Type:
Small molecule
Molecular Formula:
C20H16ClF2N5O2
Molecular Weight:
431.83
AlogP:
3.07
PSA:
85.83
HBD:
1.0
HBA:
#RotB:
5.0
Source:
CAPADENOSON
2
Small molecule
Investigational
Unknown
Unknown
Angina, Stable; Atrial Fibrillation
Adenosine A1 receptor partial agonist
CAPADENOSON
×
Maximum Phase:
2
First Approval:
None
UNII:
O519NVW73R
Molecule Type:
Small molecule
Molecular Formula:
C25H18ClN5O2S2
Molecular Weight:
520.04
AlogP:
5.51
PSA:
128.84
HBD:
2.0
HBA:
#RotB:
8.0
Source:
FUNAPIDE
2
Small molecule
Investigational
Unknown
Unknown
Erythromelalgia; Neuralgia, Postherpetic; Osteoarthritis, Knee
Unknown
FUNAPIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
A5595LHJ2L
Molecule Type:
Small molecule
Molecular Formula:
C22H14F3NO5
Molecular Weight:
429.35
AlogP:
4.25
PSA:
61.14
HBD:
0.0
HBA:
#RotB:
2.0
Source:
P276-00
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
P276-00
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BIIB021
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Neoplasms; Breast Neoplasms; Gastrointestinal Stromal Tumors
Heat shock protein HSP90 inhibitor
BIIB021
×
Maximum Phase:
2
First Approval:
None
UNII:
851B9FQ7Q0
Molecule Type:
Small molecule
Molecular Formula:
C14H15ClN6O
Molecular Weight:
318.77
AlogP:
2.13
PSA:
91.74
HBD:
1.0
HBA:
#RotB:
3.0
Source:
MILCICLIB
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular; Thymoma
Cyclin-dependent kinase 1 inhibitor
MILCICLIB
×
Maximum Phase:
2
First Approval:
None
UNII:
688000M8S8
Molecule Type:
Small molecule
Molecular Formula:
C25H32N8O
Molecular Weight:
460.59
AlogP:
2.57
PSA:
91.21
HBD:
2.0
HBA:
#RotB:
4.0
Source:
IMR-687
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
IMR-687
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAURODEOXYCHOLIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Sepsis; Dermatitis, Atopic
Unknown
TAURODEOXYCHOLIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
20668G0RPI
Molecule Type:
Small molecule
Molecular Formula:
C26H45NO6S
Molecular Weight:
499.71
AlogP:
3.4
PSA:
123.93
HBD:
4.0
HBA:
#RotB:
7.0
Source:
MK-8777
2
Small molecule
Investigational
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity; Depressive Disorder
Glutamate receptor ionotropic AMPA positive allosteric modulator
MK-8777
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ARASERTACONAZOLE
2
Small molecule
Investigational
Unknown
Unknown
Candidiasis, Vulvovaginal
Unknown
ARASERTACONAZOLE
×
Maximum Phase:
2
First Approval:
None
UNII:
PR82C5R514
Molecule Type:
Small molecule
Molecular Formula:
C20H15Cl3N2OS
Molecular Weight:
437.78
AlogP:
7.02
PSA:
27.05
HBD:
0.0
HBA:
#RotB:
6.0
Source:
RAVIDASVIR
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Nonstructural protein 5A inhibitor
RAVIDASVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
AL3G001BI8
Molecule Type:
Small molecule
Molecular Formula:
C42H50N8O6
Molecular Weight:
762.91
AlogP:
6.86
PSA:
174.64
HBD:
4.0
HBA:
#RotB:
10.0
Source:
PRADIGASTAT SODIUM
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
PRADIGASTAT SODIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
X0EWE8TT2H
Molecule Type:
Small molecule
Molecular Formula:
C25H23F3N3NaO2
Molecular Weight:
477.46
AlogP:
6.65
PSA:
75.11
HBD:
2.0
HBA:
#RotB:
6.0
Source:
VIPADENANT
2
Small molecule
Investigational
Unknown
Unknown
Parkinson Disease
Adenosine A2a receptor antagonist
VIPADENANT
×
Maximum Phase:
2
First Approval:
None
UNII:
LDR3USH1NJ
Molecule Type:
Small molecule
Molecular Formula:
C16H15N7O
Molecular Weight:
321.34
AlogP:
2.0
PSA:
121.67
HBD:
2.0
HBA:
#RotB:
3.0
Source:
CDC-801
2
Small molecule
Investigational
Unknown
Unknown
Leukemia; Myelodysplastic Syndromes
Unknown
CDC-801
×
Maximum Phase:
2
First Approval:
None
UNII:
95HB56U8P8
Molecule Type:
Small molecule
Molecular Formula:
C23H24N2O5
Molecular Weight:
408.45
AlogP:
3.23
PSA:
98.93
HBD:
1.0
HBA:
#RotB:
7.0
Source:
SCYLLITOL
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Bipolar Disorder; Down Syndrome
Unknown
SCYLLITOL
×
Maximum Phase:
2
First Approval:
None
UNII:
1VS4X81277
Molecule Type:
Small molecule
Molecular Formula:
C6H12O6
Molecular Weight:
180.16
AlogP:
-3.83
PSA:
121.38
HBD:
6.0
HBA:
#RotB:
0.0
Source:
AXELOPRAN
2
Small molecule
Investigational
Unknown
Unknown
Constipation
Mu opioid receptor antagonist
AXELOPRAN
×
Maximum Phase:
2
First Approval:
None
UNII:
85U7ROB149
Molecule Type:
Small molecule
Molecular Formula:
C26H39N3O4
Molecular Weight:
457.62
AlogP:
2.26
PSA:
107.1
HBD:
3.0
HBA:
#RotB:
9.0
Source:
AFN-1252
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Enoyl-[acyl-carrier-protein] reductase [NADH] inhibitor
AFN-1252
×
Maximum Phase:
2
First Approval:
None
UNII:
T3O718IKKM
Molecule Type:
Small molecule
Molecular Formula:
C22H21N3O3
Molecular Weight:
375.43
AlogP:
3.69
PSA:
75.44
HBD:
1.0
HBA:
#RotB:
4.0
Source:
NCX 1000
2
Small molecule
Investigational
Unknown
Unknown
Hypertension, Portal
Unknown
NCX 1000
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C38H55NO10
Molecular Weight:
685.86
AlogP:
6.55
PSA:
154.66
HBD:
2.0
HBA:
#RotB:
14.0
Source:
FIMEPINOSTAT
2
Small molecule
Investigational
Unknown
Unknown
Lymphoma; Thyroid Neoplasms
Histone deacetylase inhibitor
FIMEPINOSTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
3S9RX35S5X
Molecule Type:
Small molecule
Molecular Formula:
C23H24N8O4S
Molecular Weight:
508.56
AlogP:
2.14
PSA:
138.72
HBD:
2.0
HBA:
#RotB:
7.0
Source:
FOSRAVUCONAZOLE
2
Small molecule
Investigational
Unknown
Unknown
Mycetoma
Cytochrome P450 51 inhibitor
FOSRAVUCONAZOLE
×
Maximum Phase:
2
First Approval:
None
UNII:
L4Q6O5430L
Molecule Type:
Small molecule
Molecular Formula:
C23H20F2N5O5PS
Molecular Weight:
547.48
AlogP:
4.33
PSA:
143.38
HBD:
2.0
HBA:
#RotB:
10.0
Source:
NOLPITANTIUM
2
Small molecule
Investigational
Unknown
Unknown
Colitis, Ulcerative
Unknown
NOLPITANTIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
NR72W2V70N
Molecule Type:
Small molecule
Molecular Formula:
C37H45Cl2N2O2+
Molecular Weight:
620.69
AlogP:
8.23
PSA:
29.54
HBD:
0.0
HBA:
#RotB:
9.0
Source:
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Molecular Formula
Molecular Weight
ALogP
PSA