Display Options:
Total: 6532
Small molecule
Approved
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Diseases; Hemangiosarcoma; Brain Neoplasms; Breast Neoplasms; Neoplasms
Receptor protein-tyrosine kinase erbB-2 inhibitor
Small molecule
Approved
Unknown
Unknown
Neoplasms; Thyroid Neoplasms; Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung
Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET inhibitor
Small molecule
Approved
Unknown
Unknown
Diabetes Mellitus, Type 2; Hypercholesterolemia; Lipid Metabolism Disorders; Hyperlipidemias; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Hyperlipoproteinemia Type II
ATP-citrate synthase inhibitor
Small molecule
Approved
Unknown
Unknown
Psoriasis; Trigeminal Neuralgia; Migraine Disorders
Calcitonin gene-related peptide type 1 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Angioedemas, Hereditary
Unknown
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Carcinoma, Hepatocellular; Friedreich Ataxia; Neoplasms; Colorectal Neoplasms; Crohn Disease; Severe Acute Respiratory Syndrome; Cytomegalovirus Infections; Fever; Malaria, Falciparum; Malaria, Vivax; Schistosomiasis; Schistosomiasis haematobia; Malaria
Unknown
Small molecule
Approved
Unknown
Unknown
Pain
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
Unknown
Unknown
Alzheimer Disease
Unknown
Small molecule
Approved
Unknown
Unknown
Glioma; Leukemia, Mast-Cell; Mastocytosis, Systemic; Gastrointestinal Stromal Tumors; Neoplasms
Platelet-derived growth factor receptor alpha inhibitor
Small molecule
Approved
Unknown
Unknown
Pneumonia, Viral; Hemorrhagic Fever, Ebola; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome
Replicase polyprotein 1ab inhibitor
Small molecule
Approved
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma; Prostatic Neoplasms, Castration-Resistant; Keratosis, Actinic
Tyrosine-protein kinase SRC inhibitor
Small molecule
Approved
Unknown
Unknown
Pain; Acute Pain
Mu opioid receptor agonist
Small molecule
Approved
Unknown
Unknown
Gastrointestinal Stromal Tumors; Neoplasms
Platelet-derived growth factor receptor alpha inhibitor
Small molecule
Approved
Unknown
ORAL
Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis
Kelch-like ECH-associated protein 1 inhibitor
Small molecule
Unknown
Unknown
Unknown
Angioedemas, Hereditary
Plasma kallikrein inhibitor
Small molecule
Approved
Unknown
Unknown
Carcinoid Tumor; Endometrial Neoplasms; Glioblastoma; Leukemia; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Mesothelioma; Sarcoma; Ovarian Neoplasms; Neoplasms; Small Cell Lung Carcinoma
DNA negative modulator
Small molecule
Unknown
Unknown
Unknown
Liver Diseases; Substance-Related Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
GABA-B receptor agonist
Small molecule
Approved
Unknown
Unknown
Unknown
GABA-B receptor agonist
Small molecule
Approved
Unknown
ORAL
Substance-Related Disorders; Migraine Disorders
Serotonin 1f (5-HT1f) receptor agonist
Small molecule
Unknown
Unknown
Unknown
Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms
Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET inhibitor
Small molecule
Approved
Unknown
Unknown
Endometriosis; Leiomyoma; Pain; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms
Gonadotropin-releasing hormone receptor antagonist
Small molecule
Approved
Unknown
Unknown
Multiple Sclerosis
Sphingosine 1-phosphate receptor Edg-1 modulator
Small molecule
Approved
Unknown
Unknown
Atrophy; Muscular Atrophy, Spinal
SMN2 pre-mRNA positive modulator
Small molecule
Approved
Unknown
Unknown
Leukemia, Myeloid, Acute; Endometrial Neoplasms; Myeloproliferative Disorders; Urinary Bladder Neoplasms; Urogenital Neoplasms; Cholangiocarcinoma; Neoplasms
Fibroblast growth factor receptor 1 inhibitor
Small molecule
Approved
Unknown
Unknown
Lymphoma, Follicular; Sarcoma
Histone-lysine N-methyltransferase EZH2 inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Pituitary ACTH Hypersecretion
Cytochrome P450 11B1 inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Neuroblastoma; Trypanosomiasis, African; Chagas Disease; Leishmaniasis; Trypanosomiasis
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
GABA-B receptor agonist
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Autoimmune Diseases; HIV Infections
Envelope polyprotein GP160 inhibitor
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Glioblastoma; Liver Diseases; Carcinoma, Hepatocellular; Kidney Neoplasms; Lung Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Sarcoma; Neoplasms
Hepatocyte growth factor receptor inhibitor
Small molecule
Approved
Unknown
Unknown
Carcinoma, Squamous Cell; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Prostatic Neoplasms; Urinary Bladder Neoplasms; Mesothelioma; Lymphoma, Follicular; Sarcoma
Unknown