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Total: 10647
Small molecule
Approved
OTHER
ORAL
Unknown
Intermediate conductance calcium-activated potassium channel protein 4 opener
Small molecule
Approved
OTHER
ORAL
Cough
Slowly adapting pulmonary stretch receptor inhibitor
Small molecule
Approved
OTHER
ORAL
Diabetes Mellitus; Diabetes Mellitus, Type 2
Sulfonylurea receptor 1, Kir6.2 blocker
Small molecule
Approved
OTHER
INHALATION
Unknown
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Pneumonia; Arthritis; Bacteremia; Bacterial Infections; Endocarditis, Bacterial; Infections; Meningitis; Scarlet Fever
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
EYE; OTHER
INTRAOCULAR; INTRAVITREAL; OPHTHALMIC; ORAL; TOPICAL
Hypertension; Radius Fractures; Tooth Diseases; Adrenal Insufficiency; Aortic Coarctation; Brain Edema; Esophageal Neoplasms; Graves Disease; Head and Neck Neoplasms; Heart Failure; Lacrimal Apparatus Diseases; Lung Neoplasms; Lymphoma, T-Cell, Cutaneous; Meningeal Carcinomatosis; Osteoarthritis, Knee; Rheumatic Diseases; Rotator Cuff Injuries; Scleritis; Vitiligo; Appendicitis; Blast Crisis; Brain Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Castleman Disease; Cholangiocarcinoma; Dry Eye Syndromes; Dyspnea; Endocrine Gland Neoplasms; Endometrial Neoplasms; Fasciitis, Plantar; Glomerulonephritis; Gout; Hearing Loss; Hearing Loss, Sensorineural; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hemorrhage; Histiocytosis, Langerhans-Cell; Histiocytosis, Sinus; Intestinal Obstruction; Intracranial Hypertension; Kidney Diseases; Leptospirosis; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Plasma Cell; Leukemia, T-Cell; Lichen Planus; Liposarcoma, Myxoid; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Meningitis; Meningitis, Cryptococcal; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neck Pain; Neoplasm Metastasis; Nervous System Diseases; Pancreatic Neoplasms; POEMS Syndrome; Premature Birth; Pulmonary Fibrosis; Purpura, Schoenlein-Henoch; Purpura, Thrombotic Thrombocytopenic; Radiculopathy; Rectal Neoplasms; Red-Cell Aplasia, Pure; Respiratory Tract Diseases; Retinal Vein Occlusion; Sciatica; Stomach Neoplasms; Tonsillitis; Toxoplasmosis, Cerebral; Tuberculosis; Urinary Bladder Neoplasms; Uveitis, Intermediate; Wet Macular Degeneration; Xerostomia; Amyloidosis; Amyloidosis, Familial; Anemia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sickle Cell; Atrioventricular Block; Back Pain; Blepharitis; Bronchiolitis; Bronchopulmonary Dysplasia; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cataract; Chronic Pain; Colorectal Neoplasms; Conjunctivitis, Viral; Cysticercosis; Deafness; Deglutition Disorders; Dermatitis; Encephalitis, Herpes Simplex; Fatigue; Genital Neoplasms, Female; Glaucoma; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granuloma, Lethal Midline; Headache; HELLP Syndrome; Hernias, Diaphragmatic, Congenital; Hodgkin Disease; Hypersensitivity; Knee Injuries; Leiomyoma; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lichen Planus, Oral; Liver Cirrhosis; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Malaria; Mastoiditis; Meniere Disease; Migraine Disorders; Multiple Myeloma; Myelodysplastic Syndromes; Nausea; Nephrosis; Neuralgia; Otitis Externa; Otitis Media; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Pain; Pelvic Organ Prolapse; Plasmacytoma; Pneumonia, Viral; Postoperative Nausea and Vomiting; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Rhinitis, Allergic, Perennial; Sarcoma; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Smoldering Multiple Myeloma; Specific Language Disorder; Strabismus; Urinary Tract Infections; Uveitis, Anterior; Vaginosis, Bacterial; Vitreoretinopathy, Proliferative; Vomiting; Waldenstrom Macroglobulinemia; Wounds and Injuries; Acne Vulgaris; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Diabetic Retinopathy; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Zoster Ophthalmicus; Hypercalcemia; Infections; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Macular Edema; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
Glucocorticoid receptor agonist
Protein
Approved
OTHER
OTIC
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Unknown
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Heart Diseases; Hypercholesterolemia; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Nephrotic Syndrome; Toxemia
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
Unknown
Unknown
Nasal Obstruction
Unknown
Small molecule
Approved
OTHER
OPHTHALMIC
Unknown
Acetylcholinesterase inhibitor
Small molecule
Approved
OTHER
INJECTION; INTERSTITIAL; INTRAVENOUS
Inflammatory Breast Neoplasms; Arthritis, Rheumatoid; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Head and Neck Neoplasms; Lung Neoplasms; Lymphedema; Melanoma; Breast Neoplasms; Periodontitis; Endometrial Neoplasms; Hirschsprung Disease; Periodontal Diseases; Retinal Perforations; Stomach Neoplasms
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Glaucoma
Unknown
Small molecule
Approved
Unknown
Unknown
Psychotic Disorders
Unknown
Small molecule
Approved
Unknown
Unknown
Anxiety; Cocaine-Related Disorders; Dementia; Depressive Disorder; Schizophrenia; Parkinson Disease
Unknown
Small molecule
Approved
OTHER
ORAL
Gout
Solute carrier family 22 member 12 inhibitor
Small molecule
Approved
Unknown
Unknown
Schizophrenia; Psychotic Disorders
Unknown
Small molecule
Unknown
Unknown
Unknown
Obesity
Unknown
Small molecule
Approved
Unknown
Unknown
Bulimia Nervosa; Kidney Diseases; Liver Diseases; Substance-Related Disorders; Diabetes Mellitus; Obesity, Morbid; Obesity
Norepinephrine transporter releasing agent
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY
ORAL
Alzheimer Disease; Depression; Depressive Disorder; Depressive Disorder, Major
Monoamine oxidase inhibitor
Small molecule
Approved
OTHER
ORAL
Altitude Sickness; Uterine Cervical Neoplasms; Glaucoma; Glaucoma, Open-Angle
Carbonic anhydrase II inhibitor
Unknown
Approved
OTHER
OPHTHALMIC
Autistic Disorder
Polypeptides proteolytic enzyme
Small molecule
Approved
OTHER
ORAL
Cardiovascular Diseases; Hypertension
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
OTHER
ORAL
Cardiovascular Diseases
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
Unknown
Unknown
Macular Edema; Scleritis; Cataract; Dry Eye Syndromes; Otitis Externa; Uveitis, Anterior
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Metabolic Syndrome; Diabetes Mellitus; Lecithin Cholesterol Acyltransferase Deficiency; Kidney Diseases; Atherosclerosis; Coronary Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Kidney Calculi; Pre-Eclampsia; Angina Pectoris; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Liver Cirrhosis; Myocardial Infarction; Nephrotic Syndrome; Renal Insufficiency, Chronic; Toxemia
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
Unknown
Unknown
Chronic Pain; Pain
Unknown
Small molecule
Approved
OTHER
INJECTION; ORAL; SUBCUTANEOUS
Pregnancy; Alzheimer Disease; Endometrial Hyperplasia; HIV Infections; Pain; Primary Ovarian Insufficiency; Sleep Apnea Syndromes; Coronary Disease; Diabetes Mellitus; Endometrial Neoplasms; Heart Diseases; Hot Flashes; Hypercholesterolemia; Hypertension; Infertility; Kidney Neoplasms; Lupus Erythematosus, Systemic; Menopause; Menorrhagia; Myocardial Ischemia; Osteoporosis; Prostatic Neoplasms; Thrombosis; Turner Syndrome; Carcinoma, Renal Cell; Endometriosis; Hemorrhage; Hyperplasia; Neoplasms; Uterine Hemorrhage
Progesterone receptor agonist
Small molecule
Approved
OTHER
INJECTION; INTRAVENOUS
Neoplasms, Neuroepithelial; Anemia; Chordoma; Crohn Disease; Fallopian Tube Neoplasms; Kidney Neoplasms; Liver Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Peritoneal Neoplasms; Severe Combined Immunodeficiency; Wiskott-Aldrich Syndrome; Anemia, Sickle Cell; Breast Neoplasms, Male; Ganglioneuroblastoma; Glioma; Hematologic Diseases; Hematologic Neoplasms; Inflammatory Breast Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Osteosarcoma; Primary Myelofibrosis; Sarcoma; Brain Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Graft vs Host Disease; Leukemia; Medulloblastoma; Neuroblastoma; Neuroectodermal Tumors, Primitive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retinoblastoma; Adenocarcinoma; Carcinoma; Hodgkin Disease; Neoplasms
DNA inhibitor
Small molecule
Unknown
Unknown
Unknown
Hematologic Neoplasms; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Plasmacytoma; Rotator Cuff Injuries; Spinal Stenosis; Ischemia; Peripheral Arterial Disease; Joint Diseases; Acne Vulgaris; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Brain Edema; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Corneal Injuries; Crohn Disease; Dermatitis; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Simplex; Herpes Zoster Ophthalmicus; Hypercalcemia; Inflammation; Iridocyclitis; Iritis; Keratitis; Laryngeal Edema; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Macular Edema; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Transfusion Reaction; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
INJECTION; ORAL
Lymphoma, B-Cell, Marginal Zone; Anemia; Breast Carcinoma In Situ; Carcinoma, Medullary; Carcinoma, Pancreatic Ductal; Chordoma; Desmoplastic Small Round Cell Tumor; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Glomerulosclerosis, Focal Segmental; Head and Neck Neoplasms; Hepatoblastoma; HIV Infections; Leukemia, Plasma Cell; Liposarcoma; Lymphoma, B-Cell; Mesothelioma; Muscular Diseases; Myasthenia Gravis; Mycosis Fungoides; Nasopharyngeal Neoplasms; Nausea; Neoplasm Metastasis; Osteogenesis Imperfecta; Renal Insufficiency; Sarcoma, Synovial; Sezary Syndrome; Stiff-Person Syndrome; Thymoma; Urinary Bladder Neoplasms; Acquired Immunodeficiency Syndrome; Anemia, Sickle Cell; Arthritis, Rheumatoid; Blast Crisis; Breast Neoplasms, Male; Carcinoma, Merkel Cell; Castleman Disease; Colorectal Neoplasms; Crohn Disease; Endometrial Neoplasms; Epidermolysis Bullosa; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Gliosarcoma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Histiocytosis, Langerhans-Cell; Immune System Diseases; Immunologic Deficiency Syndromes; Leukemia, Lymphoid; Leukemia, Myelomonocytic, Juvenile; Leukemia, Prolymphocytic; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Liver Neoplasms; Lupus Erythematosus, Systemic; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Mouth Neoplasms; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive, Peripheral; Neuroendocrine Tumors; Neuromyelitis Optica; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Osteosarcoma; Pancreatic Neoplasms; Peritoneal Neoplasms; Plasmacytoma; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Purpura, Thrombocytopenic, Idiopathic; Rectal Neoplasms; Sandhoff Disease; Sarcoidosis; Skin Neoplasms; Squamous Intraepithelial Lesions; Takayasu Arteritis; Tay-Sachs Disease; Thalassemia; Thyroid Neoplasms; Tuberculosis; Uterine Cervical Neoplasms; Vasculitis; Wolman Disease; Adenocarcinoma; Amyloidosis; Amyloidosis, Familial; Anemia, Aplastic; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Behcet Syndrome; Bone Marrow Failure Disorders; Brain Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Condylomata Acuminata; Ependymoma; Ganglioneuroblastoma; Gestational Trophoblastic Disease; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Idiopathic Pulmonary Fibrosis; Immunoblastic Lymphadenopathy; Infertility; Inflammatory Breast Neoplasms; Kidney Diseases; Kidney Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lung Neoplasms; Lupus Nephritis; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Medulloblastoma; Melanoma; Menopause; Mesenchymoma; Microscopic Polyangiitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neuroectodermal Tumors, Primitive; Neutropenia; Ovarian Neoplasms; Pemphigus; Postoperative Nausea and Vomiting; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pulmonary Fibrosis; Red-Cell Aplasia, Pure; Renal Insufficiency, Chronic; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Sarcoma, Ewing; Scleritis; Scleroderma, Localized; Scleroderma, Systemic; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thrombocytopenia; Triple Negative Breast Neoplasms; Waldenstrom Macroglobulinemia; Wilms Tumor; Breast Neoplasms; Hodgkin Disease; Lymphoma; Multiple Myeloma; Neoplasms; Nephrotic Syndrome
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Dysthymic Disorder; Somatoform Disorders; Anxiety; Chest Pain; Death, Sudden, Cardiac; Dementia; Digestive System Diseases; Gastroesophageal Reflux; Low Back Pain; Myocardial Infarction; Schizophrenia; Ventricular Fibrillation; Depressive Disorder
Unknown
Small molecule
Unknown
Unknown
Unknown
Low Back Pain; Neuralgia; Chronic Pain; Gout; Optic Neuritis; Shoulder Impingement Syndrome; Tennis Elbow; Pain; Anemia; Arthritis, Rheumatoid; Asthma; Brain Neoplasms; Bursitis; Communicable Diseases; Dermatitis; Leukemia; Lymphoma; Nephrotic Syndrome; Osteoarthritis; Serum Sickness; Uveitis
Glucocorticoid receptor agonist