Display Options:
Total: 6532
Small molecule
Approved
Unknown
ORAL
Carcinoma, Ductal; Carcinoma, Pancreatic Ductal; Glioblastoma; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Kidney Diseases; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Chordoma; Colonic Neoplasms; Endometrial Neoplasms; Liposarcoma; Lymphoma; Lymphoma, Mantle-Cell; Melanoma; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Oligodendroglioma; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Ewing; Thymus Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Sarcoma; Breast Neoplasms; Neoplasms
CDK6/cyclin D1 inhibitor
Small molecule
Approved
Unknown
Unknown
Intraabdominal Infections; Pyelonephritis; Urinary Tract Infections
Bacterial beta-lactamase TEM inhibitor
Small molecule
Unknown
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
Unknown
Unknown
Glioma; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Glioblastoma
Unknown
Small molecule
Approved
Unknown
ORAL
Cholestasis; Liver Diseases; Obesity; Barrett Esophagus; Cholangitis, Sclerosing; Diarrhea; Hepatitis, Alcoholic; Lipodystrophy, Familial Partial; Non-alcoholic Fatty Liver Disease; Cholangitis; Liver Cirrhosis, Biliary
Bile acid receptor FXR agonist
Small molecule
Approved
Unknown
INTRAVENOUS
Abscess; Glucosephosphate Dehydrogenase Deficiency; Jaundice; Methemoglobinemia; Sepsis; Alzheimer Disease; Malaria; Malaria, Falciparum; Severe Acute Respiratory Syndrome; Stress Disorders, Post-Traumatic; Tooth Diseases; Wounds and Injuries; Bipolar Disorder; Dysuria; Shock, Septic; Urinary Tract Infections
Reducing agent
Small molecule
Approved
Unknown
INTRAVENOUS; ORAL
Spinal Cord Injuries; Neuralgia, Postherpetic; Unverricht-Lundborg Syndrome; Epilepsy; Seizures
Synaptic vesicle glycoprotein 2A modulator
Small molecule
Approved
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Small Cell Lung Carcinoma; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Mesothelioma; Pancreatic Neoplasms; Retroviridae Infections; Stomach Neoplasms; Uterine Cervical Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms
PARP 1, 2 and 3 inhibitor
Small molecule
Approved
Unknown
ORAL
Amyloidosis, Familial; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Kidney Diseases; Leukemia; Leukemia, Prolymphocytic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Small Cell Lung Carcinoma; Blast Crisis; Breast Neoplasms; Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Prolymphocytic, T-Cell; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Waldenstrom Macroglobulinemia; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Multiple Myeloma; Myelodysplastic Syndromes; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms
Apoptosis regulator Bcl-2 inhibitor
Small molecule
Approved
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic; Virus Diseases
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Small molecule
Approved
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Nonstructural protein 5A inhibitor
Small molecule
Approved
Unknown
Unknown
Tourette Syndrome; Parkinson Disease; Depressive Disorder, Major; Neurodegenerative Diseases; Schizophrenia; Psychotic Disorders
Unknown
Small molecule
Approved
Unknown
VAGINAL
Diabetes Mellitus, Type 1; Sarcoma, Synovial; Crohn Disease; Depressive Disorder; Erectile Dysfunction; HIV Infections; Hot Flashes; Multiple Myeloma; Myotonic Dystrophy; Primary Ovarian Insufficiency; Stress Disorders, Post-Traumatic; Substance Withdrawal Syndrome; Addison Disease; Adrenal Insufficiency; Aging; Anorexia Nervosa; Atrophic Vaginitis; Breast Neoplasms; Genital Neoplasms, Female; Infertility; Lupus Erythematosus, Systemic; Malaria; Menopause; Sexual Dysfunction, Physiological; Skin Aging; Arthritis, Rheumatoid; Dysmenorrhea; Hypogonadism; Klinefelter Syndrome; Neoplasms; Orchitis; Osteoarthritis; Pain
Unknown
Small molecule
Approved
Unknown
TOPICAL
Alopecia Areata; Dermatitis; Psoriasis; Scleroderma, Localized; Dermatitis, Atopic; Eczema
Phosphodiesterase 4 inhibitor
Small molecule
Approved
Unknown
Unknown
Hepatitis, Viral, Human; Hepatitis C; Hepatitis C, Chronic; Virus Diseases
Nonstructural protein 5A inhibitor
Small molecule
Approved
Unknown
Unknown
Pain; Blood Coagulation Disorders; Cognitive Dysfunction; Hemorrhage; Hypotension; Pre-Eclampsia; Cardiovascular Diseases; Nasal Obstruction; Obesity
Unknown
Small molecule
Approved
Unknown
OPHTHALMIC
Graft vs Host Disease; Conjunctivitis, Allergic; Dry Eye Syndromes; Eye Diseases
Integrin alpha-L/beta-2 (LFA-1) antagonist
Small molecule
Approved
Unknown
ORAL
Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2
Sodium/glucose cotransporter 2 inhibitor
Small molecule
Approved
Unknown
ORAL
Lymphoma, Large-Cell, Anaplastic; Carcinoma, Non-Small-Cell Lung; Neoplasms
ALK tyrosine kinase receptor inhibitor
Small molecule
Approved
Unknown
Unknown
Astrocytoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Lymphoma; Neuroblastoma; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Liposarcoma; Melanoma; Neoplasms; Neuroendocrine Tumors; Ovarian Neoplasms; Sarcoma; Teratoma; Thymus Neoplasms; Uterine Neoplasms; Breast Neoplasms
Cyclin-dependent kinase 4 inhibitor
Small molecule
Approved
Unknown
Unknown
Pancreatitis; Constipation
Mu opioid receptor antagonist
Small molecule
Approved
Unknown
Unknown
Renal Insufficiency, Chronic; Kidney Diseases; Liver Diseases; Hepatitis C; Hepatitis C, Chronic
Nonstructural protein 5A inhibitor
Small molecule
Approved
Unknown
Unknown
Tourette Syndrome; Huntington Disease; Movement Disorders
Synaptic vesicular amine transporter inhibitor
Small molecule
Approved
Unknown
ORAL
Chagas Disease; Leishmaniasis; Trypanosomiasis
Unknown
Small molecule
Approved
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Small molecule
Approved
Unknown
ORAL
Breast Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
Unknown
ORAL
Kidney Diseases; Liver Diseases; Atrial Fibrillation; Atrial Flutter; Hemorrhage; Thromboembolism; Thrombosis; Venous Thromboembolism
Coagulation factor X inhibitor
Small molecule
Unknown
Unknown
Unknown
Diarrhea
Tryptophan 5-hydroxylase inhibitor
Small molecule
Approved
Unknown
ORAL
Vaginal Discharge; Infections; Trichomonas Infections; Vaginosis, Bacterial
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Liver Diseases; Multiple System Atrophy; Parkinson Disease
Monoamine oxidase B inhibitor
Small molecule
Approved
Unknown
Unknown
Renal Insufficiency, Chronic; Kidney Diseases; Liver Diseases; Hepatitis C; Hepatitis C, Chronic
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Small molecule
Approved
Unknown
Unknown
Liver Diseases; Biliary Tract Neoplasms; Malignant Carcinoid Syndrome; Carcinoid Heart Disease; Neuroendocrine Tumors
Tryptophan 5-hydroxylase inhibitor
Small molecule
Approved
Unknown
TOPICAL
Wounds and Injuries; Impetigo
DNA gyrase inhibitor
Small molecule
Approved
Unknown
ORAL
Glioma; Urinary Bladder Neoplasms; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteosarcoma; Pancreatic Neoplasms; Rhabdoid Tumor; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Kaposi; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Genital Neoplasms, Female; Glioblastoma; Head and Neck Neoplasms; Lung Neoplasms; Lymphoma, Mantle-Cell; Melanoma; Mesothelioma; Oligodendroglioma; Prostatic Neoplasms, Castration-Resistant; Thyroid Neoplasms; Carcinoma, Non-Small-Cell Lung; Liposarcoma; Breast Neoplasms; Neoplasms
Cyclin-dependent kinase 4 inhibitor