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Total: 10647
Small molecule
Approved
OTHER
ORAL
Schizophrenia; Alzheimer Disease; Anus Neoplasms; Burkitt Lymphoma; Carcinoma, Verrucous; Crohn Disease; Diffuse Intrinsic Pontine Glioma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioma; Hodgkin Disease; Hypopharyngeal Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Juvenile; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Medulloblastoma; Melanoma; Niemann-Pick Diseases; Oligodendroglioma; Oropharyngeal Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Skin Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Anemia, Sickle Cell; Astrocytoma; Brain Diseases; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Glioblastoma; Gliosarcoma; HIV Infections; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Myelodysplastic Syndromes; Neuroblastoma; Ovarian Neoplasms; Pituitary ACTH Hypersecretion; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Sezary Syndrome; Spinal Cord Neoplasms; Thrombocythemia, Essential; Thyroid Neoplasms; Urinary Bladder Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Mesothelioma; Multiple Myeloma; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Neoplasms
Histone deacetylase 1 inhibitor
Unknown
Approved
Unknown
Unknown
Psoriasis; Skin Diseases; Severe Acute Respiratory Syndrome
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER
INTRAVENOUS; ORAL
Glioblastoma; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Chagas Disease; Granulomatous Disease, Chronic; Candidiasis, Oral; Coccidioidomycosis; Leukopenia; Mycoses; Aspergillosis; Candidiasis; Neutropenia
Cytochrome P450 51 inhibitor
Small molecule
Approved
Unknown
ORAL
Alzheimer Disease; Amyotrophic Lateral Sclerosis; Restless Legs Syndrome; Supranuclear Palsy, Progressive; Parkinson Disease
Unknown
Unknown
Approved
IMMUNE SYSTEM
TOPICAL
Condylomata Acuminata; Carcinoma, Basal Cell; Prostatic Neoplasms; Virus Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Asthma; Bronchial Spasm; Bronchitis; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive
Unknown
Small molecule
Approved
Unknown
Unknown
Melanosis
Sunscreen
Combination
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Alcohol Drinking; Alzheimer Disease; Amphetamine-Related Disorders; Cocaine-Related Disorders; Friedreich Ataxia; Machado-Joseph Disease; Marijuana Abuse; Parkinson Disease; Psychotic Disorders; Substance-Related Disorders; Acute Coronary Syndrome; Alcoholism; Lung Neoplasms; Neoplasms; Schizophrenia; Smoking Cessation; Tobacco Use Disorder
Neuronal acetylcholine receptor; alpha4/beta2 partial agonist
Small molecule
Approved
OTHER; PEDIATRICS; RESPIRATORY
INHALATION; NASAL
Pulmonary Disease, Chronic Obstructive; Chronic Disease; Hypersensitivity; Severe Acute Respiratory Syndrome; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal
Glucocorticoid receptor agonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Autoimmune Diseases; HIV Infections; Infections
Human immunodeficiency virus type 1 protease inhibitor
Small molecule
Unknown
Unknown
Unknown
Hepatitis; Liver Cirrhosis; Hepatitis B, Chronic; Virus Diseases
DNA polymerase/reverse transcriptase inhibitor
Small molecule
Approved
Unknown
Unknown
Gliosarcoma; Hemorrhagic Fever, Ebola; Leukemia, Myeloid, Acute; Osteosarcoma; Adenocarcinoma; Adrenal Cortex Neoplasms; Ascites; Brain Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Lung Neoplasms; Melanoma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pheochromocytoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Sarcoma, Alveolar Soft Part; Small Cell Lung Carcinoma; Stomach Neoplasms; Thymoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; von Hippel-Lindau Disease; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Kidney Neoplasms; Prostatic Neoplasms; Urogenital Neoplasms; Neoplasms
Unknown
Protein
Approved
RHEUMATOLOGY
IV (INFUSION)
Behcet Syndrome; Myasthenia Gravis; Polychondritis, Relapsing; Vitiligo; Alopecia; Alopecia Areata; Diabetes Mellitus, Type 1; Graft vs Host Disease; Hypertension; Immunoglobulin G4-Related Disease; Lupus Erythematosus, Systemic; Multiple Myeloma; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Nephrotic Syndrome; Peanut Hypersensitivity; Psoriasis; Sarcoidosis; Scleroderma, Diffuse; Spondylitis, Ankylosing; Takayasu Arteritis; Uveitis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Colitis, Ulcerative; Crohn Disease; Dermatomyositis; Giant Cell Arteritis; Granulomatosis with Polyangiitis; Lupus Nephritis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Sjogren's Syndrome; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Immune System Diseases
T-lymphocyte activation antigen CD80 inhibitor
Small molecule
Approved
Unknown
Unknown
Tonsillitis; Pain; Acid-Base Imbalance; Electrolytes
pH lowering agent
Small molecule
Approved
HEMATOLOGY; OTHER
INTRAVENOUS
Lymphoma, Follicular; Anemia, Sickle Cell; Burkitt Lymphoma; Glioma; Head and Neck Neoplasms; Hematologic Neoplasms; Leukemia, Promyelocytic, Acute; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Medulloblastoma; Multiple Myeloma; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Adenocarcinoma, Follicular; Anemia, Aplastic; Blast Crisis; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hodgkin Disease; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Melanoma; Ovarian Neoplasms; Peritoneal Neoplasms; Severe Acute Respiratory Syndrome; Thalassemia; Thyroid Neoplasms; Graft vs Host Disease; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Peripheral; Myeloproliferative Disorders; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia; Anemia; Anemia, Refractory, with Excess of Blasts; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms
DNA (cytosine-5)-methyltransferase 1 inhibitor
Small molecule
Unknown
Unknown
Unknown
Staphylococcal Infections; Infections; Impetigo
70S ribosome inhibitor
Small molecule
Approved
CARDIOVASCULAR; OTHER; RESPIRATORY
ORAL
Anemia, Sickle Cell; Altitude Sickness; Asthma; Hypoplastic Left Heart Syndrome; Severe Acute Respiratory Syndrome; Idiopathic Pulmonary Fibrosis; Vascular Diseases; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension
Endothelin receptor, ET-A/ET-B antagonist
Protein
Unknown
Unknown
Unknown
Carcinoid Tumor; Acromegaly; Malignant Carcinoid Syndrome
Somatostatin receptor 2 agonist
Small molecule
Approved
OTHER
ORAL
Head and Neck Neoplasms; Paraparesis, Tropical Spastic; Hepatitis C; Leukemia, Biphenotypic, Acute; HTLV-I Infections; Liver Cirrhosis, Biliary; Multiple Sclerosis, Relapsing-Remitting; Acquired Immunodeficiency Syndrome; HIV Infections; Infections; Virus Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Heart Failure; Hypertension; Alzheimer Disease; Autistic Disorder; Hypertension, Portal; Lesch-Nyhan Syndrome; Liver Cirrhosis; Phenylketonurias; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER; UROLOGY AND KIDNEY
INTRAVENOUS
Meningitis; Appendicitis; Cholecystitis; Pancreatitis; Peritonitis; Pneumonia; Pneumonia, Ventilator-Associated; Bacterial Infections; Intraabdominal Infections; Pyelonephritis; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Protein
Approved
Unknown
Unknown
Neuroendocrine Tumors; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Diarrhea; Dumping Syndrome; Esophagitis, Peptic; Graves Ophthalmopathy; Hyperglycemia; Intestinal Diseases; Intestinal Obstruction; Acromegaly; Carcinoid Heart Disease; Carcinoid Tumor; Endocrine Gland Neoplasms; Malignant Carcinoid Syndrome; Neoplasms; Pituitary Neoplasms; Polycystic Kidney, Autosomal Dominant; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms
Unknown
Small molecule
Approved
UROLOGY AND KIDNEY
INTRAVENOUS
Adenocarcinoma; Astrocytoma; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma; Colonic Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Genital Neoplasms, Female; Glioma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Neoplasms; Oligodendroglioma; Peritoneal Neoplasms; Prostatic Neoplasms; Urethral Neoplasms; Uterine Cervical Neoplasms; Adenoma; Arthritis, Rheumatoid; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Glioblastoma; Gliosarcoma; Hodgkin Disease; Insulinoma; Ischemia; Kidney Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Peripheral Arterial Disease; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Small Cell Lung Carcinoma; Somatostatinoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Hepatoblastoma; Lymphoma; Lymphoma, Mantle-Cell; Neoplasm Metastasis; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Carcinoma, Renal Cell; Neoplasms
FK506-binding protein 1A inhibitor
Small molecule
Approved
Unknown
ORAL
Urinary Bladder Neoplasms; Carcinoma, Renal Cell; Endometrial Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Thyroid Neoplasms; Adenocarcinoma; Brain Neoplasms; Carcinoma, Ductal; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Esophageal Neoplasms; Glioma; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pituitary Neoplasms; Stomach Neoplasms; Uterine Cervical Neoplasms; Brain Diseases; Breast Neoplasms; Head and Neck Neoplasms; Sarcoma; Neoplasms
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Esophageal Neoplasms; Glioma; Multiple Sclerosis; Neoplasms; Schizophrenia; Sleep Initiation and Maintenance Disorders; Stroke; Brain Injuries; Depressive Disorder; Disorders of Excessive Somnolence; Fatigue; Obesity; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Sleep Apnea, Obstructive; Sleep Wake Disorders
Dopamine transporter inhibitor
Small molecule
Approved
Unknown
Unknown
Colonic Neoplasms; Breast Neoplasms; Chordoma; Huntington Disease; Alzheimer Disease; Cerebellar Ataxia; Giant Cell Tumors; Glioma; Graft vs Host Disease; Hypertension, Pulmonary; Leukemia, Myeloid, Acute; Melanoma; Neurilemmoma; Parkinson Disease; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Synovitis, Pigmented Villonodular; Gastrointestinal Stromal Tumors; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Sarcoma; Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Antibody
Approved
HEMATOLOGY
IV (INFUSION)
End Stage Liver Disease; Glomerulonephritis, Membranoproliferative; Graft vs Host Disease; Hemolysis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Dermatomyositis; Diabetes Mellitus; Macular Degeneration; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Thrombocytopenia; Guillain-Barre Syndrome; Hemolytic-Uremic Syndrome; Leukemia; Myasthenia Gravis; Neuromyelitis Optica; Atypical Hemolytic Uremic Syndrome; Hemoglobinuria; Hemoglobinuria, Paroxysmal; Immune System Diseases
Complement C5 inhibitor
Enzyme
Approved
OTHER
INJECTION
Empyema, Pleural; Pulmonary Embolism; ST Elevation Myocardial Infarction; Empyema; Infections; Stroke; Thrombosis
Plasminogen activator
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Hypertriglyceridemia; AIDS Dementia Complex; Arthritis, Rheumatoid; Cognitive Dysfunction; Graft vs Host Disease; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Stroke; Acquired Immunodeficiency Syndrome; Infections; Autoimmune Diseases; HIV Infections; Virus Diseases
C-C chemokine receptor type 5 antagonist
Small molecule
Approved
Unknown
Unknown
Coronary Artery Disease
Diagnostic agent
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
TRANSDERMAL
Alzheimer Disease; Fibromyalgia; Stroke; Parkinson Disease; Restless Legs Syndrome
D2-like dopamine receptor agonist
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Parkinson Disease; Scleroderma, Systemic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Bcr/Abl fusion protein