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Total: 10647
Protein
Approved
Unknown
Unknown
Heart Failure; Joint Diseases; Mitochondrial Diseases; Angioedema; Angioedemas, Hereditary
Unknown
Small molecule
Approved
Unknown
Unknown
Osteoarthritis
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY
ORAL
Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Hypertension; Renal Insufficiency; Schizophrenia; Stomach Neoplasms; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 2
Dipeptidyl peptidase IV inhibitor
Small molecule
Approved
CANCER; OTHER; RESPIRATORY
ORAL
Breast Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Adenocarcinoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Granuloma, Plasma Cell; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Multiple Myeloma; Neurofibromatosis 2; Stomach Neoplasms; Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Lymphoma, Large B-Cell, Diffuse; Neoplasms
ALK tyrosine kinase receptor inhibitor
Protein
Approved
EYE
INJECTION
Carcinoma, Non-Small-Cell Lung; Corneal Neovascularization; Glioma; Histoplasmosis; Lymphoma; Lymphoma, Non-Hodgkin; Adenocarcinoma, Follicular; Astrocytoma; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Renal Cell; Central Serous Chorioretinopathy; Colonic Neoplasms; Endometrial Neoplasms; Gliosarcoma; Graves Ophthalmopathy; Leukemia; Multiple Myeloma; Oligodendroglioma; Pseudoxanthoma Elasticum; Rectal Neoplasms; Retinal Diseases; Small Cell Lung Carcinoma; Thyroid Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Vitreous Hemorrhage; Glaucoma; Glaucoma, Neovascular; Melanoma; Myopia, Degenerative; Retinal Vein Occlusion; Retinopathy of Prematurity; Telangiectasis; Colorectal Neoplasms; Diabetic Retinopathy; Macular Degeneration; Macular Edema; Neoplasms; Retinal Neovascularization; Wet Macular Degeneration
Placenta growth factor inhibitor
Small molecule
Approved
Unknown
Unknown
Heart Arrest
Unknown
Small molecule
Approved
OTHER
INHALATION
Asthma; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
Small molecule
Approved
OTHER
TOPICAL
Lice Infestations
Nicotinic acetylcholine receptor agonist
Small molecule
Approved
Unknown
Unknown
Otitis Media with Effusion; Alcohol Drinking; Anxiety; Arthritis, Rheumatoid; Celiac Disease; Gingivitis; Acne Vulgaris; Amyotrophic Lateral Sclerosis; Burns; Chemical and Drug Induced Liver Injury; Hidradenitis Suppurativa; Ileus; Intervertebral Disc Degeneration; Severe Acute Respiratory Syndrome; Tinea Pedis; Cardiovascular Diseases; Dental Caries; Hemorrhoids; Pain; Periodontitis; Tension-Type Headache; Tooth Diseases; Multiple Sclerosis; Short Bowel Syndrome
Unknown
Small molecule
Approved
Unknown
Unknown
Essential Hypertension; Hypertension; Cardiovascular Diseases
Unknown
Small molecule
Approved
OTHER
INTRAVENOUS
Arthritis, Rheumatoid; Heart Failure
Diagnostic agent
Antibody
Approved
DERMATOLOGY
INJECTION
Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Fallopian Tube Neoplasms; Glioma; HIV Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasm Metastasis; Nerve Sheath Neoplasms; Neuroblastoma; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroperitoneal Neoplasms; Skin Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Basal Cell Nevus Syndrome; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Colonic Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Gliosarcoma; Histiocytoma, Malignant Fibrous; Hodgkin Disease; Inflammatory Breast Neoplasms; Liposarcoma; Meningioma; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Pituitary Neoplasms; Prostatic Neoplasms; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Kaposi; Sarcoma, Synovial; Stomach Neoplasms; Thyroid Neoplasms; Urinary Bladder Neoplasms; Adenocarcinoma of Lung; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Glioblastoma; Head and Neck Neoplasms; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Mesothelioma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Small Cell Lung Carcinoma; Urogenital Neoplasms; Melanoma; Neoplasms
Cytotoxic T-lymphocyte protein 4 inhibitor
Small molecule
Approved
Unknown
Unknown
Parkinson Disease; Multiple System Atrophy; Parkinsonian Disorders
Diagnostic agent
Small molecule
Approved
DERMATOLOGY
ORAL
Glioma; Lymphoma; Skin Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Craniopharyngioma; Histiocytosis; Histiocytosis, Langerhans-Cell; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Multiple Myeloma; Thyroid Neoplasms; Melanoma; Neoplasms
Serine/threonine-protein kinase B-raf inhibitor
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Asthma; Heart Failure; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive
Unknown
Small molecule
Unknown
Unknown
Unknown
Neoplasms; Depressive Disorder, Major; Lymphoma; Nervous System Diseases; Obesity; Schizophrenia; Cognitive Dysfunction; Dementia; Dermatitis; Dermatitis, Atopic; Diabetes Mellitus, Type 2; Non-alcoholic Fatty Liver Disease; Respiratory Distress Syndrome; Asthma; Bronchiectasis; Diabetic Nephropathies; Psoriasis; Bronchitis, Chronic; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive
Phosphodiesterase 4 inhibitor
Small molecule
Approved
DERMATOLOGY; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Kidney Diseases; Alcoholism; Diabetic Neuropathies; Migraine Disorders; Epilepsy; Neuralgia, Postherpetic; Restless Legs Syndrome
Voltage-gated calcium channel modulator
Small molecule
Approved
RESPIRATORY
ORAL
Multiple Sclerosis; Alveolitis, Extrinsic Allergic; Bronchiolitis Obliterans; Burns; Cardiomyopathy, Hypertrophic; Glomerulosclerosis, Focal Segmental; Heart Failure; Leiomyoma; Liver Cirrhosis; Lung Diseases, Interstitial; Nephrotic Syndrome; Neurofibromatosis 1; Pneumoconiosis; Proteinuria; Pulmonary Fibrosis; Radiation Pneumonitis; Renal Insufficiency; Renal Insufficiency, Chronic; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Diabetic Foot; Keloid; Pneumonia; Idiopathic Pulmonary Fibrosis; Immune System Diseases
Unknown
Small molecule
Approved
IMMUNE SYSTEM
ORAL
Thrombocytopenia; Hepatitis C; Hepatitis C, Chronic; Virus Diseases
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Small molecule
Approved
Unknown
Unknown
Glioblastoma; Leukemia, Biphenotypic, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Pneumonia; Alopecia Areata; Arthritis, Rheumatoid; beta-Thalassemia; Breast Neoplasms; Bronchiolitis Obliterans; Cachexia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Hematologic Neoplasms; Hidradenitis Suppurativa; HIV Infections; Hodgkin Disease; Hypereosinophilic Syndrome; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Lichen Planus; Lupus Erythematosus, Discoid; Lymphoma; Multiple Myeloma; Necrobiosis Lipoidica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Thrombocythemia, Essential; Dermatitis, Atopic; Graft vs Host Disease; Lymphohistiocytosis, Hemophagocytic; Myeloproliferative Disorders; Pancreatic Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Severe Acute Respiratory Syndrome; Vitiligo; Neoplasms
Unknown
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Kidney Diseases; Erectile Dysfunction
Phosphodiesterase 5A inhibitor
Small molecule
Approved
Unknown
Unknown
Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms
Androgen Receptor antagonist
Protein
Approved
GASTROINTESTINAL
ORAL
Liver Diseases; Thrombocytopenia; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Infections; Virus Diseases
Hepatitis C virus serine protease, NS3/NS4A inhibitor
Small molecule
Approved
OTHER
ORAL
Hepatitis C; Insulin Resistance; Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Small molecule
Approved
Unknown
Unknown
Marijuana Abuse; Memory Disorders; Anxiety Disorders; Depressive Disorder, Major; Depressive Disorder
Unknown
Small molecule
Approved
GASTROINTESTINAL
ORAL
Clostridium Infections; Diarrhea; Infections
DNA-directed RNA polymerase inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Polycystic Ovary Syndrome; Renal Insufficiency; Diabetes Mellitus, Type 1; Obesity; Diabetic Nephropathies; Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2
Sodium/glucose cotransporter 2 inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Antibody
Unknown
Unknown
Unknown
Graft vs Host Disease; Arthritis, Rheumatoid; Emphysema; Glomerulonephritis, Membranous; Kidney Diseases; Multiple Sclerosis; Myositis; Purpura, Thrombocytopenic, Idiopathic; Scleroderma, Systemic; Sjogren's Syndrome; Vasculitis; Immune System Diseases; Lupus Erythematosus, Systemic; Lupus Nephritis
Tumor necrosis factor ligand superfamily member 13B inhibitor
Small molecule
Approved
CARDIOVASCULAR; HEMATOLOGY; OTHER
ORAL
Obesity, Morbid; Renal Insufficiency, Chronic; Acute Coronary Syndrome; Anemia, Sickle Cell; Aortic Valve Disease; Heart Diseases; Hemorrhage; Ischemia; Multiple Myeloma; Thromboembolism; Antiphospholipid Syndrome; Coronary Disease; Diabetes Mellitus, Type 2; Hematoma; Ischemic Stroke; Liver Cirrhosis; Myocardial Infarction; Neoplasms; Peripheral Arterial Disease; Renal Insufficiency; Rheumatic Heart Disease; Severe Acute Respiratory Syndrome; Stroke; Thrombocytopenia; Venous Thromboembolism; Atrial Fibrillation; Pulmonary Embolism; Thrombosis; Venous Thrombosis
Coagulation factor X inhibitor
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Amyotrophic Lateral Sclerosis; Depressive Disorder; Depressive Disorder, Major; Neuralgia, Postherpetic; Epilepsy; Seizures
KCNQ (Kv7) potassium channel opener
Small molecule
Approved
CARDIOVASCULAR; OTHER
ORAL
Hypertension; Stroke
Type-1 angiotensin II receptor antagonist
Antibody
Approved
CANCER; OTHER
INJECTION
Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Enteropathy-Associated T-Cell Lymphoma; Graft vs Host Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Mast-Cell; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Scleroderma, Diffuse; Sezary Syndrome; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Hodgkin Disease; Lymphoma, Large-Cell, Anaplastic; Neoplasms
Tubulin inhibitor
Enzyme
Approved
Unknown
Unknown
Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Asparagine hydrolytic enzyme