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Total: 10647
Small molecule
Approved
Unknown
IV (INFUSION)
Hematologic Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Myelodysplastic Syndromes; Amyloidosis, Familial; Breast Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Hairy Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, T-Cell, Peripheral; Multiple Myeloma; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Waldenstrom Macroglobulinemia; Immunoblastic Lymphadenopathy; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Neoplasms
Unknown
Small molecule
Approved
MUSCULOSKELETAL; OTHER
ORAL
Tourette Syndrome; Movement Disorders; Huntington Disease
Synaptic vesicular amine transporter inhibitor
Protein
Approved
OTHER
SINGLE-USE
Hearing Loss; Diabetes Mellitus, Type 1; Scleroderma, Diffuse; Arthritis, Juvenile; Familial Mediterranean Fever; Hepatitis, Alcoholic; Gout; Cryopyrin-Associated Periodic Syndromes; Immune System Diseases; Pericarditis
Interleukin-1 beta inhibitor
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Urinary Incontinence; Urinary Bladder, Overactive; Urinary Incontinence, Urge
Muscarinic acetylcholine receptor M2 antagonist
Small molecule
Approved
Unknown
INTRAVENOUS
Colonic Neoplasms; Rectal Neoplasms; Esophageal Neoplasms; Anemia; Colorectal Neoplasms; Osteosarcoma
Unknown
Small molecule
Approved
EYE
OPHTHALMIC
Dry Eye Syndromes; Cataract; Panuveitis; Uveitis; Inflammation; Uveitis, Anterior
Glucocorticoid receptor agonist
Small molecule
Approved
HEMATOLOGY; OTHER
ORAL
Kidney Calculi; Carcinoma; Kidney Diseases; Renal Insufficiency, Chronic; Dyspnea; Edema, Cardiac; Inappropriate ADH Syndrome; Liver Cirrhosis; Polycystic Kidney, Autosomal Dominant; Cardiovascular Diseases; Heart Failure; Hyponatremia; Polycystic Kidney Diseases
Vasopressin V2 receptor antagonist
Small molecule
Approved
Unknown
ORAL
Atrial Fibrillation; Atrial Flutter; Heart Failure; Arrhythmias, Cardiac
Unknown
Small molecule
Approved
OTHER
ORAL
Liver Diseases; Stress Disorders, Post-Traumatic; Bipolar Disorder; Psychotic Disorders; Schizophrenia
Dopamine D2 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Rhinitis, Allergic, Perennial; Conjunctivitis, Allergic; Pruritus
Histamine H1 receptor antagonist
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM
TOPICAL
Amyotrophic Lateral Sclerosis; Brain Injuries; Cough; Migraine Disorders; Pruritus; Stroke; Facial Pain; HIV Infections; Hypertension, Pulmonary; Myofascial Pain Syndromes; Nausea; Neuralgia, Postherpetic; Neuroma; Tennis Elbow; Vomiting; Angina, Stable; Breast Neoplasms; Diabetic Neuropathies; Head and Neck Neoplasms; Herpes Zoster; Osteoarthritis, Knee; Peripheral Nervous System Diseases; Arthralgia; Arthritis; Back Pain; Bursitis; Contusions; Muscle Cramp; Myalgia; Neuralgia; Osteoarthritis; Pain; Sprains and Strains; Tendinopathy
Vanilloid receptor opener
Small molecule
Approved
Unknown
Unknown
HIV Infections; Neoplasms; Schistosomiasis haematobia; Fever; Malaria, Falciparum; Malaria, Vivax; Malaria
Ferriprotoporphyrin IX inhibitor
Small molecule
Approved
Unknown
Unknown
HIV Infections; Schistosomiasis haematobia; Fever; Malaria, Falciparum; Malaria, Vivax; Malaria
Ferriprotoporphyrin IX inhibitor
Small molecule
Approved
OTHER; PEDIATRICS
ORAL
Tourette Syndrome; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Obesity; Tuberous Sclerosis; Epilepsy; Epilepsy, Complex Partial; Spasms, Infantile
Gamma-amino-N-butyrate transaminase inhibitor
Antibody
Approved
RHEUMATOLOGY
SUBCUTANEOUS
Carcinoma, Renal Cell; Breast Neoplasms; Carcinoma, Pancreatic Ductal; Macular Degeneration; Myelodysplastic Syndromes; Pulmonary Disease, Chronic Obstructive; Anemia, Sickle Cell; Aortic Aneurysm, Abdominal; Arthritis, Rheumatoid; Atrial Fibrillation; Behcet Syndrome; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dry Eye Syndromes; Hepatitis, Alcoholic; Lung Neoplasms; Melanoma; Mucocutaneous Lymph Node Syndrome; Osteoarthritis; Peripheral Arterial Disease; Polymyalgia Rheumatica; Pyoderma; Sarcoidosis, Pulmonary; Schnitzler Syndrome; Urticaria; Atherosclerosis; Carcinoma, Non-Small-Cell Lung; Fever; Gout; Pneumonia; Severe Acute Respiratory Syndrome; Still's Disease, Adult-Onset; Arthritis, Juvenile; Cryopyrin-Associated Periodic Syndromes; Familial Mediterranean Fever; Immune System Diseases; Mevalonate Kinase Deficiency
Interleukin-1 beta inhibitor
Small molecule
Approved
Unknown
Unknown
HIV Infections; Asthma; Heart Diseases; Acute Coronary Syndrome; Anemia, Sickle Cell; Atrial Fibrillation; Coronary Disease; Myocardial Infarction; Renal Insufficiency, Chronic; ST Elevation Myocardial Infarction; Thrombosis
Unknown
Protein
Unknown
Unknown
Unknown
Amyloidosis; Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Leukemia, Prolymphocytic; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mycosis Fungoides; Plasmacytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sezary Syndrome; Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine; Graft vs Host Disease; Kidney Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Prostatic Neoplasms, Castration-Resistant; Waldenstrom Macroglobulinemia; Multiple Myeloma; Neoplasms
26S proteosome inhibitor
Small molecule
Approved
Unknown
ORAL
Diabetes Mellitus, Type 1; Glucose Intolerance; Diabetes Mellitus, Type 2; Myocardial Infarction; Polycystic Ovary Syndrome; Diabetes Mellitus
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
INJECTION
Renal Insufficiency, Chronic; Gram-Positive Bacterial Infections; Infections; Bacteremia; Pneumonia, Bacterial; Staphylococcal Skin Infections; Bacterial Infections
Unknown
Small molecule
Approved
OTHER
TOPICAL
Ectoparasitic Infestations; Lice Infestations; Otitis Externa; Pruritus
Unknown
Protein
Approved
HEMATOLOGY
INTRAVENOUS
Astrocytoma; Carcinoma, Pancreatic Ductal; Gliosarcoma; Hodgkin Disease; Inflammatory Breast Neoplasms; Leukemia; Liposarcoma; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Oligodendroglioma; Pancreatic Neoplasms; Sezary Syndrome; Triple Negative Breast Neoplasms; Adenocarcinoma, Follicular; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; HIV Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Melanoma; Multiple Myeloma; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Immunoblastic Lymphadenopathy; Lymphoma; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neoplasms
Histone deacetylase inhibitor
Small molecule
Approved
CANCER; IMMUNE SYSTEM; OTHER; UROLOGY AND KIDNEY
ORAL
Acute Coronary Syndrome; Adenocarcinoma; Breast Neoplasms, Male; Central Nervous System Neoplasms; Colonic Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Hamartoma Syndrome, Multiple; Hematologic Diseases; Leukemia; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Non-Hodgkin; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Progeria; Sarcoma, Synovial; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Adenoma, Islet Cell; Brain Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cholangiocarcinoma; Chondrosarcoma; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Endometrial Hyperplasia; Endometrial Neoplasms; Ependymoma; Epilepsy; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatitis C; Hodgkin Disease; Hyperaldosteronism; Kidney Diseases; Leukemia, Myeloid, Acute; Liver Neoplasms; Lung Neoplasms; Lymphangioleiomyomatosis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Cutaneous; Macular Degeneration; Mastocytosis, Systemic; Melanoma; Meningioma; Mesothelioma; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neurofibromatosis 1; Neurofibromatosis 2; Oligodendroglioma; Osteosarcoma; Pancreatic Neoplasms; Peutz-Jeghers Syndrome; Polycystic Kidney Diseases; Sarcoma; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Thymus Neoplasms; Thyroid Neoplasms; Tuberculosis; Urinary Bladder Neoplasms; Uterine Neoplasms; Uveitis; Waldenstrom Macroglobulinemia; Carcinoid Tumor; Carcinoma; Coronary Restenosis; Cytomegalovirus Infections; Endocardial Cushion Defects; Graft vs Host Disease; Infections; Kidney Neoplasms; Lymphoma, Large B-Cell, Diffuse; Malignant Carcinoid Syndrome; Polycystic Kidney, Autosomal Dominant; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency; Renal Insufficiency, Chronic; Skin Neoplasms; Stomach Neoplasms; Angiomyolipoma; Astrocytoma; Breast Neoplasms; Carcinoma, Renal Cell; Immune System Diseases; Neoplasms; Neuroendocrine Tumors; Tuberous Sclerosis
FK506-binding protein 1A inhibitor
Small molecule
Approved
OTHER
ORAL
Barrett Esophagus; Esophagitis, Peptic; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Peptic Ulcer; Stomach Ulcer
Potassium-transporting ATPase inhibitor
Small molecule
Unknown
Unknown
Unknown
Angina, Stable; Hypertension; Kidney Calculi; Kidney Diseases; Non-alcoholic Fatty Liver Disease; Cardiovascular Diseases; Tumor Lysis Syndrome; Gout; Hyperuricemia
Xanthine dehydrogenase inhibitor
Small molecule
Approved
Unknown
Unknown
Irritable Bowel Syndrome; Low Back Pain; Neuralgia; Fibromyalgia; Peripheral Nervous System Diseases; Depressive Disorder
Unknown
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Osteoporosis, Postmenopausal; Endometrial Hyperplasia; Menopause; Osteoporosis
Unknown
Small molecule
Approved
Unknown
Unknown
Influenza, Human; Metabolic Syndrome; Renal Insufficiency; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Hypercholesterolemia; Hyperlipidemias; Ischemic Stroke; Lipid Metabolism Disorders; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Rhinitis, Allergic, Seasonal; Conjunctivitis, Allergic; Dermatitis; Rhinitis, Allergic, Perennial
Unknown
Small molecule
Approved
Unknown
SUBLINGUAL; TRANSDERMAL
Bipolar Disorder; Psychotic Disorders; Schizophrenia
Unknown
Small molecule
Approved
Unknown
Unknown
Carcinoma, Hepatocellular; Colorectal Neoplasms; Corneal Neovascularization; Glioblastoma; Lymphoma; Psoriasis; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chondrosarcoma; Dermatofibrosarcoma; Fallopian Tube Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Gliosarcoma; Hemangiosarcoma; Kidney Neoplasms; Leiomyosarcoma; Leukemia, Myeloid, Acute; Liposarcoma; Lung Neoplasms; Lymphedema; Macular Degeneration; Melanoma; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Osteosarcoma; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma, Alveolar Soft Part; Small Cell Lung Carcinoma; Solitary Fibrous Tumors; Stomach Neoplasms; Telangiectasia, Hereditary Hemorrhagic; Thyroid Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Renal Cell; Ovarian Neoplasms; Sarcoma; Neoplasms
Unknown
Small molecule
Approved
CANCER; OTHER
INJECTION; INTRAVENOUS
Fallopian Tube Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Cutaneous; Multiple Myeloma; Mycosis Fungoides; Ovarian Neoplasms; Peritoneal Neoplasms; Sezary Syndrome; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Lung Neoplasms; Lymphoma; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Neoplasms
Dihydrofolate reductase inhibitor
Antibody
Approved
DERMATOLOGY; OTHER
INJECTION
Ichthyosis; Arthritis, Rheumatoid; Behcet Syndrome; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Giant Cell Arteritis; Graft vs Host Disease; Hematologic Neoplasms; Hidradenitis Suppurativa; Liver Cirrhosis, Biliary; Multiple Sclerosis; Pemphigoid, Bullous; Sarcoidosis; Uveitis; Colitis; Colitis, Ulcerative; Dermatomyositis; Lupus Erythematosus, Systemic; Pouchitis; Spondylitis, Ankylosing; Takayasu Arteritis; Arthritis, Psoriatic; Crohn Disease; Immune System Diseases; Psoriasis
Interleukin-12 inhibitor
Protein
Approved
IMMUNE SYSTEM
INJECTION
Angioedema; Angioedemas, Hereditary
Plasma kallikrein inhibitor
Small molecule
Approved
Unknown
Unknown
Cataract; Conjunctivitis, Bacterial; Eye Infections
Unknown
Antibody
Approved
OTHER; RHEUMATOLOGY
INJECTION
Labyrinth Diseases; Asthma; Diabetes Mellitus, Type 1; Sarcoidosis; Arthritis, Juvenile; Osteoarthritis; Spondylarthropathies; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Immune System Diseases; Spondylitis; Spondylitis, Ankylosing
TNF-alpha inhibitor